Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S12

Gene

Rps12-ps3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal proteinUniRule annotationImported

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-72649. Translation initiation complex formation.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-MMU-72702. Ribosomal scanning and start codon recognition.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S12UniRule annotation
Gene namesi
Name:Rps12-ps3Imported
Synonyms:Rps12Imported
ORF Names:mCG_132913Imported, mCG_6749Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componentsi: Chromosome 10, Chromosome 19

Organism-specific databases

MGIiMGI:98105. Rps12.
MGI:3704503. Rps12-ps3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

TopDownProteomicsiQ6ZWZ6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000061983.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100481.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 110Ribosomal_L7AeInterPro annotationAdd BLAST94

Sequence similaritiesi

Belongs to the ribosomal protein S12e family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3406. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000018318.
HOVERGENiHBG001720.
KOiK02951.
OMAiNCDEPTY.
OrthoDBiEOG091G0UB5.
TreeFamiTF300196.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR000530. Ribosomal_S12e.
[Graphical view]
PANTHERiPTHR11843. PTHR11843. 1 hit.
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
PRINTSiPR00972. RIBSOMALS12E.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiPS01189. RIBOSOMAL_S12E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZWZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEGIAAGG VMDVNTALQE VLKTALIHDG LARGIREAAK ALDKRQAHLC
60 70 80 90 100
VLASNCDEPM YVKLVEALCA EHQINLIKVD DNKKLGEWVG LCKIDREGKP
110 120 130
RKVVGCSCVV VKDYGKESQA KDVIEEYFKC KK
Length:132
Mass (Da):14,515
Last modified:July 5, 2004 - v1
Checksum:i45AD1274D55FFA25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139040 Genomic DNA. No translation available.
AC160147 Genomic DNA. No translation available.
BC002079 mRNA. Translation: AAH02079.1.
BC089338 mRNA. Translation: AAH89338.1.
BC089339 mRNA. Translation: AAH89339.1.
BC090257 mRNA. Translation: AAH90257.1.
BC092044 mRNA. Translation: AAH92044.1.
BC096653 mRNA. Translation: AAH96653.1.
BC099377 mRNA. Translation: AAH99377.1.
AK002848 mRNA. Translation: BAB22404.1.
AK008057 mRNA. Translation: BAB25433.1.
AK032757 mRNA. Translation: BAC28009.1.
AK166923 mRNA. Translation: BAE39118.1.
AK166992 mRNA. Translation: BAE39171.1.
AK168324 mRNA. Translation: BAE40263.1.
AK169215 mRNA. Translation: BAE40986.1.
CH466540 Genomic DNA. Translation: EDL04768.1.
CH466525 Genomic DNA. Translation: EDL11714.1.
RefSeqiNP_035425.2. NM_011295.6.
UniGeneiMm.371846.
Mm.386780.
Mm.440324.
Mm.442130.
Mm.490389.

Genome annotation databases

EnsembliENSMUST00000073926; ENSMUSP00000073581; ENSMUSG00000061983.
ENSMUST00000086764; ENSMUSP00000083973; ENSMUSG00000067038.
GeneIDi20042.
KEGGimmu:20042.
UCSCiuc007epx.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139040 Genomic DNA. No translation available.
AC160147 Genomic DNA. No translation available.
BC002079 mRNA. Translation: AAH02079.1.
BC089338 mRNA. Translation: AAH89338.1.
BC089339 mRNA. Translation: AAH89339.1.
BC090257 mRNA. Translation: AAH90257.1.
BC092044 mRNA. Translation: AAH92044.1.
BC096653 mRNA. Translation: AAH96653.1.
BC099377 mRNA. Translation: AAH99377.1.
AK002848 mRNA. Translation: BAB22404.1.
AK008057 mRNA. Translation: BAB25433.1.
AK032757 mRNA. Translation: BAC28009.1.
AK166923 mRNA. Translation: BAE39118.1.
AK166992 mRNA. Translation: BAE39171.1.
AK168324 mRNA. Translation: BAE40263.1.
AK169215 mRNA. Translation: BAE40986.1.
CH466540 Genomic DNA. Translation: EDL04768.1.
CH466525 Genomic DNA. Translation: EDL11714.1.
RefSeqiNP_035425.2. NM_011295.6.
UniGeneiMm.371846.
Mm.386780.
Mm.440324.
Mm.442130.
Mm.490389.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100481.

Proteomic databases

TopDownProteomicsiQ6ZWZ6.

Protocols and materials databases

DNASUi20042.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000073926; ENSMUSP00000073581; ENSMUSG00000061983.
ENSMUST00000086764; ENSMUSP00000083973; ENSMUSG00000067038.
GeneIDi20042.
KEGGimmu:20042.
UCSCiuc007epx.2. mouse.

Organism-specific databases

CTDi6206.
MGIiMGI:98105. Rps12.
MGI:3704503. Rps12-ps3.

Phylogenomic databases

eggNOGiKOG3406. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000018318.
HOVERGENiHBG001720.
KOiK02951.
OMAiNCDEPTY.
OrthoDBiEOG091G0UB5.
TreeFamiTF300196.

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-72649. Translation initiation complex formation.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-MMU-72702. Ribosomal scanning and start codon recognition.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000061983.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR000530. Ribosomal_S12e.
[Graphical view]
PANTHERiPTHR11843. PTHR11843. 1 hit.
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
PRINTSiPR00972. RIBSOMALS12E.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiPS01189. RIBOSOMAL_S12E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6ZWZ6_MOUSE
AccessioniPrimary (citable) accession number: Q6ZWZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.