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Protein

40S ribosomal protein S12

Gene

Rps12

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationImported

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-72649. Translation initiation complex formation.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-MMU-72702. Ribosomal scanning and start codon recognition.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S12UniRule annotation
Gene namesi
Name:Rps12Imported
Synonyms:Rps12-ps3Imported
ORF Names:mCG_132913Imported, mCG_6749Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:98105. Rps12.
MGI:3704503. Rps12-ps3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

TopDownProteomicsiQ6ZWZ6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000061983.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 110Ribosomal_L7AeInterPro annotationAdd BLAST94

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eS12 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3406. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00390000018318.
HOVERGENiHBG001720.
KOiK02951.
OMAiGLRECAK.
OrthoDBiEOG091G0UB5.
TreeFamiTF300196.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiView protein in InterPro
IPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR000530. Ribosomal_S12e.
PANTHERiPTHR11843. PTHR11843. 1 hit.
PfamiView protein in Pfam
PF01248. Ribosomal_L7Ae. 1 hit.
PRINTSiPR00972. RIBSOMALS12E.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiView protein in PROSITE
PS01189. RIBOSOMAL_S12E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6ZWZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEGIAAGG VMDVNTALQE VLKTALIHDG LARGIREAAK ALDKRQAHLC
60 70 80 90 100
VLASNCDEPM YVKLVEALCA EHQINLIKVD DNKKLGEWVG LCKIDREGKP
110 120 130
RKVVGCSCVV VKDYGKESQA KDVIEEYFKC KK
Length:132
Mass (Da):14,515
Last modified:July 5, 2004 - v1
Checksum:i45AD1274D55FFA25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139040 Genomic DNA. No translation available.
AC160147 Genomic DNA. No translation available.
BC002079 mRNA. Translation: AAH02079.1.
BC089338 mRNA. Translation: AAH89338.1.
BC089339 mRNA. Translation: AAH89339.1.
BC090257 mRNA. Translation: AAH90257.1.
BC092044 mRNA. Translation: AAH92044.1.
BC096653 mRNA. Translation: AAH96653.1.
BC099377 mRNA. Translation: AAH99377.1.
AK002848 mRNA. Translation: BAB22404.1.
AK008057 mRNA. Translation: BAB25433.1.
AK032757 mRNA. Translation: BAC28009.1.
AK166923 mRNA. Translation: BAE39118.1.
AK166992 mRNA. Translation: BAE39171.1.
AK168324 mRNA. Translation: BAE40263.1.
AK169215 mRNA. Translation: BAE40986.1.
CH466540 Genomic DNA. Translation: EDL04768.1.
CH466525 Genomic DNA. Translation: EDL11714.1.
RefSeqiNP_035425.2. NM_011295.6.
UniGeneiMm.371846.
Mm.386780.
Mm.440324.
Mm.442130.
Mm.490389.

Genome annotation databases

EnsembliENSMUST00000086764; ENSMUSP00000083973; ENSMUSG00000067038.
ENSMUST00000218107; ENSMUSP00000151305; ENSMUSG00000061983.
ENSMUST00000220070; ENSMUSP00000151271; ENSMUSG00000061983.
GeneIDi20042.
KEGGimmu:20042.
UCSCiuc007epx.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ6ZWZ6_MOUSE
AccessioniPrimary (citable) accession number: Q6ZWZ6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported