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Protein

60S ribosomal protein L35

Gene

Rpl35

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_279505. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_292264. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_302277. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_308559. Formation of a pool of free 40S subunits.
REACT_311765. Peptide chain elongation.
REACT_319670. Eukaryotic Translation Termination.
REACT_331340. SRP-dependent cotranslational protein targeting to membrane.
REACT_340387. L13a-mediated translational silencing of Ceruloplasmin expression.

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L35
Gene namesi
Name:Rpl35
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componentsi: Chromosome 1, Chromosome 2

Organism-specific databases

MGIiMGI:1913739. Rpl35.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 12312260S ribosomal protein L35PRO_0000320063Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei19 – 191N6-acetyllysineBy similarity
Modified residuei43 – 431N6-acetyllysineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ6ZWV7.
PaxDbiQ6ZWV7.
PRIDEiQ6ZWV7.

PTM databases

PhosphoSiteiQ6ZWV7.

Expressioni

Gene expression databases

BgeeiQ6ZWV7.
CleanExiMM_RPL35.
GenevisibleiQ6ZWV7. MM.

Interactioni

Protein-protein interaction databases

BioGridi211511. 2 interactions.
IntActiQ6ZWV7. 5 interactions.
MINTiMINT-1862907.
STRINGi10090.ENSMUSP00000099843.

Structurei

3D structure databases

ProteinModelPortaliQ6ZWV7.
SMRiQ6ZWV7. Positions 2-66.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L29P family.Curated

Phylogenomic databases

eggNOGiCOG0255.
GeneTreeiENSGT00390000016384.
HOGENOMiHOG000207749.
HOVERGENiHBG000862.
InParanoidiQ6ZWV7.
KOiK02918.
OMAiIAFPQRK.
OrthoDBiEOG7TBC4G.
PhylomeDBiQ6ZWV7.
TreeFamiTF314951.

Family and domain databases

Gene3Di1.10.287.310. 1 hit.
HAMAPiMF_00374. Ribosomal_L29.
InterProiIPR001854. Ribosomal_L29.
IPR018254. Ribosomal_L29_CS.
[Graphical view]
PfamiPF00831. Ribosomal_L29. 1 hit.
[Graphical view]
SUPFAMiSSF46561. SSF46561. 1 hit.
TIGRFAMsiTIGR00012. L29. 1 hit.
PROSITEiPS00579. RIBOSOMAL_L29. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6ZWV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKIKARDLR GKKKEELLKQ LDDLKVELSQ LRVAKVTGGA ASKLSKIRVV
60 70 80 90 100
RKSIARVLTV INQTQKENLR KFYKGKKYKP LDLRPKKTRA MRRRLTKHEE
110 120
KLKTKKQQRK ERLYPLRKYA VKA
Length:123
Mass (Da):14,553
Last modified:July 5, 2004 - v1
Checksum:i67B76951361674EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK010639 mRNA. Translation: BAB27082.1.
AK012335 mRNA. Translation: BAB28169.1.
AK151707 mRNA. Translation: BAE30629.1.
AK169650 mRNA. Translation: BAE41274.1.
AL844588 Genomic DNA. Translation: CAM46062.1.
BC094634 mRNA. Translation: AAH94634.1.
BC125652 mRNA. Translation: AAI25653.1.
BC125656 mRNA. Translation: AAI25657.1.
CCDSiCCDS16015.1.
RefSeqiNP_079868.1. NM_025592.3.
UniGeneiMm.345333.

Genome annotation databases

EnsembliENSMUST00000080861; ENSMUSP00000079672; ENSMUSG00000062997.
ENSMUST00000102782; ENSMUSP00000099843; ENSMUSG00000078193.
GeneIDi66489.
KEGGimmu:66489.
UCSCiuc008jnz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK010639 mRNA. Translation: BAB27082.1.
AK012335 mRNA. Translation: BAB28169.1.
AK151707 mRNA. Translation: BAE30629.1.
AK169650 mRNA. Translation: BAE41274.1.
AL844588 Genomic DNA. Translation: CAM46062.1.
BC094634 mRNA. Translation: AAH94634.1.
BC125652 mRNA. Translation: AAI25653.1.
BC125656 mRNA. Translation: AAI25657.1.
CCDSiCCDS16015.1.
RefSeqiNP_079868.1. NM_025592.3.
UniGeneiMm.345333.

3D structure databases

ProteinModelPortaliQ6ZWV7.
SMRiQ6ZWV7. Positions 2-66.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi211511. 2 interactions.
IntActiQ6ZWV7. 5 interactions.
MINTiMINT-1862907.
STRINGi10090.ENSMUSP00000099843.

PTM databases

PhosphoSiteiQ6ZWV7.

Proteomic databases

MaxQBiQ6ZWV7.
PaxDbiQ6ZWV7.
PRIDEiQ6ZWV7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000080861; ENSMUSP00000079672; ENSMUSG00000062997.
ENSMUST00000102782; ENSMUSP00000099843; ENSMUSG00000078193.
GeneIDi66489.
KEGGimmu:66489.
UCSCiuc008jnz.1. mouse.

Organism-specific databases

CTDi11224.
MGIiMGI:1913739. Rpl35.

Phylogenomic databases

eggNOGiCOG0255.
GeneTreeiENSGT00390000016384.
HOGENOMiHOG000207749.
HOVERGENiHBG000862.
InParanoidiQ6ZWV7.
KOiK02918.
OMAiIAFPQRK.
OrthoDBiEOG7TBC4G.
PhylomeDBiQ6ZWV7.
TreeFamiTF314951.

Enzyme and pathway databases

ReactomeiREACT_279505. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_292264. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_302277. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_308559. Formation of a pool of free 40S subunits.
REACT_311765. Peptide chain elongation.
REACT_319670. Eukaryotic Translation Termination.
REACT_331340. SRP-dependent cotranslational protein targeting to membrane.
REACT_340387. L13a-mediated translational silencing of Ceruloplasmin expression.

Miscellaneous databases

NextBioi321836.
PROiQ6ZWV7.
SOURCEiSearch...

Gene expression databases

BgeeiQ6ZWV7.
CleanExiMM_RPL35.
GenevisibleiQ6ZWV7. MM.

Family and domain databases

Gene3Di1.10.287.310. 1 hit.
HAMAPiMF_00374. Ribosomal_L29.
InterProiIPR001854. Ribosomal_L29.
IPR018254. Ribosomal_L29_CS.
[Graphical view]
PfamiPF00831. Ribosomal_L29. 1 hit.
[Graphical view]
SUPFAMiSSF46561. SSF46561. 1 hit.
TIGRFAMsiTIGR00012. L29. 1 hit.
PROSITEiPS00579. RIBOSOMAL_L29. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Bone marrow and Thymus.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Brain and Mammary gland.

Entry informationi

Entry nameiRL35_MOUSE
AccessioniPrimary (citable) accession number: Q6ZWV7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 5, 2004
Last modified: July 22, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.