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Protein

60S ribosomal protein L10

Gene

Rpl10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L10
Alternative name(s):
Protein QM homolog
Gene namesi
Name:Rpl10
Synonyms:Qm
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componentsi: Chromosome 9, Chromosome X

Organism-specific databases

MGIiMGI:105943. Rpl10.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: MGI
  • cytosolic large ribosomal subunit Source: MGI
  • endoplasmic reticulum Source: MGI
  • membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 21421360S ribosomal protein L10PRO_0000147107Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei32 – 321Citrulline1 Publication
Cross-linki188 – 188Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Post-translational modificationi

Citrullinated by PADI4.1 Publication

Keywords - PTMi

Citrullination, Isopeptide bond, Ubl conjugation

Proteomic databases

EPDiQ6ZWV3.
MaxQBiQ6ZWV3.
PaxDbiQ6ZWV3.
PeptideAtlasiQ6ZWV3.
PRIDEiQ6ZWV3.
TopDownProteomicsiQ6ZWV3.

PTM databases

iPTMnetiQ6ZWV3.
PhosphoSiteiQ6ZWV3.
SwissPalmiQ6ZWV3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000008682.
CleanExiMM_RPL10.
ExpressionAtlasiQ6ZWV3. baseline and differential.
GenevisibleiQ6ZWV3. MM.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S) (By similarity).By similarity

Protein-protein interaction databases

BioGridi226050. 3 interactions.
IntActiQ6ZWV3. 4 interactions.
MINTiMINT-1837923.
STRINGi10090.ENSMUSP00000125806.

Structurei

3D structure databases

ProteinModelPortaliQ6ZWV3.
SMRiQ6ZWV3. Positions 3-207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L10e family.Curated

Phylogenomic databases

eggNOGiKOG0857. Eukaryota.
COG0197. LUCA.
GeneTreeiENSGT00390000003897.
HOVERGENiHBG002287.
InParanoidiQ6ZWV3.
KOiK02866.
OMAiEHKMATG.
OrthoDBiEOG091G0H9M.
PhylomeDBiQ6ZWV3.
TreeFamiTF300082.

Family and domain databases

CDDicd01433. Ribosomal_L16_L10e. 1 hit.
Gene3Di3.90.1170.10. 1 hit.
InterProiIPR001197. Ribosomal_L10e.
IPR016180. Ribosomal_L10e/L16.
IPR018255. Ribosomal_L10e_CS.
[Graphical view]
PfamiPF00252. Ribosomal_L16. 1 hit.
[Graphical view]
PIRSFiPIRSF005590. Ribosomal_L10. 1 hit.
SUPFAMiSSF54686. SSF54686. 1 hit.
TIGRFAMsiTIGR00279. uL16_euk_arch. 1 hit.
PROSITEiPS01257. RIBOSOMAL_L10E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6ZWV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG
60 70 80 90 100
HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN
110 120 130 140 150
KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVIE
160 170 180 190 200
ALRRAKFKFP GRQKIHISKK WGFTKFNADE FEDMVAEKRL IPDGCGVKYI
210
PNRGPLDKWR ALHS
Length:214
Mass (Da):24,604
Last modified:January 23, 2007 - v3
Checksum:i0860CECC91DF74FE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti150 – 1501E → G in AAH86917 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M93980 mRNA. Translation: AAA16894.1.
X75312 mRNA. Translation: CAA53061.1.
AK011022 mRNA. Translation: BAB27339.1.
AK012561 mRNA. Translation: BAB28316.1.
AK014054 mRNA. Translation: BAB29134.1.
AK088777 mRNA. Translation: BAC40566.1.
AK144831 mRNA. Translation: BAE26087.1.
AK146217 mRNA. Translation: BAE26985.1.
AK151416 mRNA. Translation: BAE30381.1.
AK151655 mRNA. Translation: BAE30584.1.
AK151736 mRNA. Translation: BAE30650.1.
AK152123 mRNA. Translation: BAE30965.1.
AK152854 mRNA. Translation: BAE31547.1.
AK153345 mRNA. Translation: BAE31921.1.
AK160618 mRNA. Translation: BAE35918.1.
AK166610 mRNA. Translation: BAE38892.1.
AK167239 mRNA. Translation: BAE39361.1.
AK167966 mRNA. Translation: BAE39963.1.
AK168854 mRNA. Translation: BAE40675.1.
CH466519 Genomic DNA. Translation: EDL27744.1.
CH466650 Genomic DNA. Translation: EDL29836.1.
BC024901 mRNA. Translation: AAH24901.1.
BC048872 mRNA. Translation: AAH48872.1.
BC082293 mRNA. Translation: AAH82293.1.
BC083327 mRNA. Translation: AAH83327.1.
BC086917 mRNA. Translation: AAH86917.1.
BC092383 mRNA. Translation: AAH92383.1.
BC098204 mRNA. Translation: AAH98204.1.
BC099437 mRNA. Translation: AAH99437.1.
CCDSiCCDS41019.1.
PIRiJC2013.
RefSeqiNP_443067.1. NM_052835.3.
UniGeneiMm.100113.
Mm.315052.
Mm.352201.
Mm.472707.

Genome annotation databases

EnsembliENSMUST00000008826; ENSMUSP00000008826; ENSMUSG00000008682.
ENSMUST00000074085; ENSMUSP00000082055; ENSMUSG00000008682.
ENSMUST00000076364; ENSMUSP00000125806; ENSMUSG00000058443.
GeneIDi110954.
KEGGimmu:110954.
UCSCiuc009toc.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M93980 mRNA. Translation: AAA16894.1.
X75312 mRNA. Translation: CAA53061.1.
AK011022 mRNA. Translation: BAB27339.1.
AK012561 mRNA. Translation: BAB28316.1.
AK014054 mRNA. Translation: BAB29134.1.
AK088777 mRNA. Translation: BAC40566.1.
AK144831 mRNA. Translation: BAE26087.1.
AK146217 mRNA. Translation: BAE26985.1.
AK151416 mRNA. Translation: BAE30381.1.
AK151655 mRNA. Translation: BAE30584.1.
AK151736 mRNA. Translation: BAE30650.1.
AK152123 mRNA. Translation: BAE30965.1.
AK152854 mRNA. Translation: BAE31547.1.
AK153345 mRNA. Translation: BAE31921.1.
AK160618 mRNA. Translation: BAE35918.1.
AK166610 mRNA. Translation: BAE38892.1.
AK167239 mRNA. Translation: BAE39361.1.
AK167966 mRNA. Translation: BAE39963.1.
AK168854 mRNA. Translation: BAE40675.1.
CH466519 Genomic DNA. Translation: EDL27744.1.
CH466650 Genomic DNA. Translation: EDL29836.1.
BC024901 mRNA. Translation: AAH24901.1.
BC048872 mRNA. Translation: AAH48872.1.
BC082293 mRNA. Translation: AAH82293.1.
BC083327 mRNA. Translation: AAH83327.1.
BC086917 mRNA. Translation: AAH86917.1.
BC092383 mRNA. Translation: AAH92383.1.
BC098204 mRNA. Translation: AAH98204.1.
BC099437 mRNA. Translation: AAH99437.1.
CCDSiCCDS41019.1.
PIRiJC2013.
RefSeqiNP_443067.1. NM_052835.3.
UniGeneiMm.100113.
Mm.315052.
Mm.352201.
Mm.472707.

3D structure databases

ProteinModelPortaliQ6ZWV3.
SMRiQ6ZWV3. Positions 3-207.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi226050. 3 interactions.
IntActiQ6ZWV3. 4 interactions.
MINTiMINT-1837923.
STRINGi10090.ENSMUSP00000125806.

PTM databases

iPTMnetiQ6ZWV3.
PhosphoSiteiQ6ZWV3.
SwissPalmiQ6ZWV3.

Proteomic databases

EPDiQ6ZWV3.
MaxQBiQ6ZWV3.
PaxDbiQ6ZWV3.
PeptideAtlasiQ6ZWV3.
PRIDEiQ6ZWV3.
TopDownProteomicsiQ6ZWV3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000008826; ENSMUSP00000008826; ENSMUSG00000008682.
ENSMUST00000074085; ENSMUSP00000082055; ENSMUSG00000008682.
ENSMUST00000076364; ENSMUSP00000125806; ENSMUSG00000058443.
GeneIDi110954.
KEGGimmu:110954.
UCSCiuc009toc.2. mouse.

Organism-specific databases

CTDi6134.
MGIiMGI:105943. Rpl10.

Phylogenomic databases

eggNOGiKOG0857. Eukaryota.
COG0197. LUCA.
GeneTreeiENSGT00390000003897.
HOVERGENiHBG002287.
InParanoidiQ6ZWV3.
KOiK02866.
OMAiEHKMATG.
OrthoDBiEOG091G0H9M.
PhylomeDBiQ6ZWV3.
TreeFamiTF300082.

Miscellaneous databases

PROiQ6ZWV3.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000008682.
CleanExiMM_RPL10.
ExpressionAtlasiQ6ZWV3. baseline and differential.
GenevisibleiQ6ZWV3. MM.

Family and domain databases

CDDicd01433. Ribosomal_L16_L10e. 1 hit.
Gene3Di3.90.1170.10. 1 hit.
InterProiIPR001197. Ribosomal_L10e.
IPR016180. Ribosomal_L10e/L16.
IPR018255. Ribosomal_L10e_CS.
[Graphical view]
PfamiPF00252. Ribosomal_L16. 1 hit.
[Graphical view]
PIRSFiPIRSF005590. Ribosomal_L10. 1 hit.
SUPFAMiSSF54686. SSF54686. 1 hit.
TIGRFAMsiTIGR00279. uL16_euk_arch. 1 hit.
PROSITEiPS01257. RIBOSOMAL_L10E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL10_MOUSE
AccessioniPrimary (citable) accession number: Q6ZWV3
Secondary accession number(s): P45634, Q569M8, Q5M9K8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 119 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.