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Protein

40S ribosomal protein S27

Gene

Rps27

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the small ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 18S rRNAs (By similarity).By similarity

Cofactori

Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri38 – 60C4-typeSequence analysisAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase
R-MMU-72649 Translation initiation complex formation
R-MMU-72689 Formation of a pool of free 40S subunits
R-MMU-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-MMU-72702 Ribosomal scanning and start codon recognition
R-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S27
Gene namesi
Name:Rps27Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componentsi: Chromosome 3, Chromosome 9

Organism-specific databases

MGIiMGI:1888676 Rps27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001490521 – 8440S ribosomal protein S27Add BLAST84

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei11PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ6ZWU9
MaxQBiQ6ZWU9
PaxDbiQ6ZWU9
PeptideAtlasiQ6ZWU9
PRIDEiQ6ZWU9
TopDownProteomicsiQ6ZWU9

PTM databases

iPTMnetiQ6ZWU9
PhosphoSitePlusiQ6ZWU9
SwissPalmiQ6ZWU9

Expressioni

Gene expression databases

BgeeiENSMUSG00000050621
CleanExiMM_RPS27
ExpressionAtlasiQ6ZWU9 baseline and differential
GenevisibleiQ6ZWU9 MM

Interactioni

Subunit structurei

Component of the small ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi208248, 3 interactors
IntActiQ6ZWU9, 2 interactors
MINTiQ6ZWU9
STRINGi10090.ENSMUSP00000132102

Structurei

3D structure databases

ProteinModelPortaliQ6ZWU9
SMRiQ6ZWU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri38 – 60C4-typeSequence analysisAdd BLAST23

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG1779 Eukaryota
COG2051 LUCA
GeneTreeiENSGT00390000013514
HOVERGENiHBG000252
InParanoidiQ6ZWU9
KOiK02978
OMAiQEGCSFR
OrthoDBiEOG091G157G
PhylomeDBiQ6ZWU9
TreeFamiTF300265

Family and domain databases

HAMAPiMF_00371 Ribosomal_S27e, 1 hit
InterProiView protein in InterPro
IPR000592 Ribosomal_S27e
IPR011332 Ribosomal_zn-bd
PANTHERiPTHR11594 PTHR11594, 1 hit
PfamiView protein in Pfam
PF01667 Ribosomal_S27e, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004466 Ribosomal_S27e, 1 hit
SUPFAMiSSF57829 SSF57829, 1 hit
PROSITEiView protein in PROSITE
PS01168 RIBOSOMAL_S27E, 1 hit

Sequencei

Sequence statusi: Complete.

Q6ZWU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLAKDLLHP SPEEEKRKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA
60 70 80
QTVVLCVGCS TVLCQPTGGK ARLTEGCSFR RKQH
Length:84
Mass (Da):9,461
Last modified:January 23, 2007 - v3
Checksum:i242C4466AC8A8900
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014294 mRNA Translation: BAB29250.1
AK088320 mRNA Translation: BAC40279.1
AK166551 mRNA Translation: BAE38849.1
BC048352 mRNA Translation: AAH48352.1
BC055693 mRNA Translation: AAH55693.1
CCDSiCCDS50970.1
RefSeqiNP_001177187.1, NM_001190258.1
NP_081291.1, NM_027015.4
UniGeneiMm.270283
Mm.371611

Genome annotation databases

EnsembliENSMUST00000053150; ENSMUSP00000060523; ENSMUSG00000050621
ENSMUST00000170122; ENSMUSP00000132102; ENSMUSG00000090733
GeneIDi100043813
57294
KEGGimmu:100043813
mmu:57294
UCSCiuc008qbl.2 mouse

Similar proteinsi

Entry informationi

Entry nameiRS27_MOUSE
AccessioniPrimary (citable) accession number: Q6ZWU9
Secondary accession number(s): Q3TLE3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 131 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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