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Q6ZWR6 (SYNE1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nesprin-1
Alternative name(s):
Enaptin
Myocyte nuclear envelope protein 1
Short name=Myne-1
Nuclear envelope spectrin repeat protein 1
Synaptic nuclear envelope protein 1
Short name=Syne-1
Gene names
Name:Syne1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length8799 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. May be involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm By similarity. Required for centrosome migration to the apical cell surface during early ciliogenesis. Ref.7

Subunit structure

Dimer. Core component of the LINC complex which is composed of inner nuclear membrane SUN domain-containing proteins coupled to outer nuclear membrane KASH domain-containing nesprins. SUN domain-containing proteins interact with A-type lamins of the nuclear lamina, while at the other end of the complex, nesprins interact with unique cytoskeletal components. Interacts with SYNE3. May interact with MUSK. Interacts with EMD and LMNA in vitro By similarity. Interacts with F-actin via its N-terminal domain. Ref.1 Ref.9

Subcellular location

Nucleus outer membrane; Single-pass type IV membrane protein; Cytoplasmic side Potential. Nucleus. Nucleus envelope. Cytoplasmcytoskeleton. Cytoplasmmyofibrilsarcomere By similarity. Note: The largest part of the protein is cytoplasmic, while its C-terminal part is associated with the nuclear envelope, most probably the outer nuclear membrane. In skeletal and smooth muscles, a significant amount is found in the sarcomeres By similarity. Ref.1 Ref.2 Ref.5 Ref.8

Tissue specificity

Expressed in C2F3 and CH310T1/2 cells, brain and skeletal muscle (at protein level). Ref.2 Ref.9

Domain

The KASH domain, which contains a transmembrane domain, mediates the nuclear envelope targeting and is involved in the binding to SUN1 and SUN2 through recognition of their SUN domains By similarity.

Sequence similarities

Belongs to the nesprin family.

Contains 1 actin-binding domain.

Contains 2 CH (calponin-homology) domains.

Contains 9 HAT repeats.

Contains 1 KASH domain.

Contains 44 spectrin repeats.

Contains 11 TPR repeats.

Sequence caution

The sequence AAG24393.1 differs from that shown. Reason: Frameshift at positions 6810, 7656 and 7658.

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q6ZWR6-1)

Also known as: Nesprin-1 Giant; Enaptin;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q6ZWR6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-7828: Missing.
     7829-7878: IAVAQENKIQ...WQHLLDLMAA → MVVAEDLHGPRMAEDSSVDADLPDCDCDVS
     8218-8219: Missing.
     8328-8328: S → SDVVIPENPEAYVKLTENAIRNTS
Isoform 3 (identifier: Q6ZWR6-3)

Also known as: Syne-1A;

The sequence of this isoform differs from the canonical sequence as follows:
     1-7828: Missing.
     7829-7878: IAVAQENKIQ...WQHLLDLMAA → MVVAEDLHGPRMAEDSSVDADLPDCDCDVS
     8218-8219: Missing.
Isoform 4 (identifier: Q6ZWR6-4)

Also known as: Syne-1B;

The sequence of this isoform differs from the canonical sequence as follows:
     8218-8219: Missing.
Note: Incomplete sequence.
Isoform 5 (identifier: Q6ZWR6-5)

Also known as: Enaptin-165;

The sequence of this isoform differs from the canonical sequence as follows:
     103-103: K → KSMYRGSP
     297-313: Missing.
     1435-1441: DIKTMEM → EYVLHHF
     1442-8799: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 87998799Nesprin-1
PRO_0000392209

Regions

Topological domain1 – 87488748Cytoplasmic Potential
Transmembrane8749 – 876921Helical; Anchor for type IV membrane protein; Potential
Topological domain8770 – 879930Perinuclear space Potential
Domain1 – 289289Actin-binding
Domain27 – 134108CH 1
Domain178 – 283106CH 2
Repeat592 – 62433HAT 1
Repeat915 – 94935TPR 1
Repeat1015 – 104834TPR 2
Repeat1103 – 113533HAT 2
Repeat1127 – 1229103Spectrin 1
Repeat1423 – 145533HAT 3
Repeat1447 – 1546100Spectrin 2
Repeat1538 – 157235TPR 3
Repeat1553 – 164997Spectrin 3
Repeat1656 – 1759104Spectrin 4
Repeat2087 – 2191105Spectrin 5
Repeat2305 – 240298Spectrin 6
Repeat2407 – 2509103Spectrin 7
Repeat2516 – 2618103Spectrin 8
Repeat2703 – 274240HAT 4
Repeat2841 – 2982142Spectrin 9
Repeat2947 – 298034TPR 4
Repeat3065 – 3167103Spectrin 10
Repeat3174 – 3274101Spectrin 11
Repeat3281 – 3383103Spectrin 12
Repeat3390 – 348697Spectrin 13
Repeat3479 – 351234TPR 5
Repeat3490 – 3593104Spectrin 14
Repeat3817 – 3916100Spectrin 15
Repeat3923 – 4030108Spectrin 16
Repeat4138 – 423699Spectrin 17
Repeat4345 – 4447103Spectrin 18
Repeat4454 – 4556103Spectrin 19
Repeat4563 – 4665103Spectrin 20
Repeat4580 – 461334TPR 6
Repeat4672 – 4772101Spectrin 21
Repeat4885 – 4987103Spectrin 22
Repeat4994 – 5095102Spectrin 23
Repeat5078 – 511033HAT 5
Repeat5102 – 5205104Spectrin 24
Repeat5212 – 5317106Spectrin 25
Repeat5426 – 552196Spectrin 26
Repeat5514 – 554734TPR 7
Repeat5528 – 562699Spectrin 27
Repeat5736 – 576934TPR 8
Repeat5747 – 5867121Spectrin 28
Repeat5961 – 599434TPR 9
Repeat5975 – 6078104Spectrin 29
Repeat6702 – 679493Spectrin 30
Repeat6777 – 680933HAT 6
Repeat6801 – 6906106Spectrin 31
Repeat6917 – 7021105Spectrin 32
Repeat7004 – 703633HAT 7
Repeat7028 – 7129102Spectrin 33
Repeat7136 – 7238103Spectrin 34
Repeat7214 – 725340HAT 8
Repeat7358 – 745598Spectrin 35
Repeat7462 – 7562101Spectrin 36
Repeat7569 – 7672104Spectrin 37
Repeat7679 – 7779101Spectrin 38
Repeat7786 – 788499Spectrin 39
Repeat7891 – 7998108Spectrin 40
Repeat7978 – 801033HAT 9
Repeat8005 – 8107103Spectrin 41
Repeat8025 – 805834TPR 10
Repeat8114 – 8214101Spectrin 42
Repeat8131 – 816535TPR 11
Repeat8445 – 8548104Spectrin 43
Repeat8555 – 8659105Spectrin 44
Domain8740 – 879960KASH
Compositional bias8665 – 873167Ser-rich

Amino acid modifications

Modified residue82271Phosphoserine By similarity
Modified residue82781Phosphothreonine By similarity
Modified residue82811Phosphoserine By similarity
Modified residue82841Phosphoserine By similarity
Modified residue83081Phosphoserine Ref.6

Natural variations

Alternative sequence1 – 78287828Missing in isoform 2 and isoform 3.
VSP_038791
Alternative sequence1031K → KSMYRGSP in isoform 5.
VSP_038792
Alternative sequence297 – 31317Missing in isoform 5.
VSP_038793
Alternative sequence1435 – 14417DIKTMEM → EYVLHHF in isoform 5.
VSP_038794
Alternative sequence1442 – 87997358Missing in isoform 5.
VSP_038795
Alternative sequence7829 – 787850IAVAQ…DLMAA → MVVAEDLHGPRMAEDSSVDA DLPDCDCDVS in isoform 2 and isoform 3.
VSP_038796
Alternative sequence8218 – 82192Missing in isoform 2, isoform 3 and isoform 4.
VSP_038797
Alternative sequence83281S → SDVVIPENPEAYVKLTENAI RNTS in isoform 2.
VSP_038798

Experimental info

Sequence conflict10861G → W in AAN03487. Ref.2
Sequence conflict11501I → T in AAN03487. Ref.2
Sequence conflict71871E → G in AAG24393. Ref.1
Sequence conflict78761M → I in AAG24393. Ref.1
Sequence conflict82661P → L in AAG24392. Ref.1
Sequence conflict82661P → L in AAG24393. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (Nesprin-1 Giant) (Enaptin) [UniParc].

Last modified March 23, 2010. Version 2.
Checksum: 2A457DC081969CF0

FASTA8,7991,009,926
        10         20         30         40         50         60 
MATSRASSRS HRDITNVMQR LQDEQEIVQK RTFTKWINSH LAKRKPPMVV DDLFEDMKDG 

        70         80         90        100        110        120 
IKLLALLEVL SGQKLPCEQG HRVKRIHAVA NIGTALKFLE GRKIKLVNIN ATDIADGRPS 

       130        140        150        160        170        180 
IVLGLMWTII LYFQIEELTS NLPQLQSLSS SASSVDSMVS TETASPPSKR KVAAKIQGNA 

       190        200        210        220        230        240 
KKTLLKWVQH TAGKQMGIEV KDFGKSWRTG LAFHSVIHAI QPELVDLEKV KTRSNRENLE 

       250        260        270        280        290        300 
DAFTIAETQL GIPRLLDPED VDVDKPDEKS IMTYVAQFLT QYPDIHGAGC DGQEDDVVFV 

       310        320        330        340        350        360 
GFTNNIALLL GFQRDDRLIL KETKVWIEQF ERDFTRAQMT ESSLQDKYQA FKHFRVQYEM 

       370        380        390        400        410        420 
KRKQVEHIIQ PLQRDGKLTL DQALVKQCWE RVSSRLFDWH IQLDKSLPAP LGTIGAWLYR 

       430        440        450        460        470        480 
AEVALREEIT IQQVHEETAN TIQRKLEQHK DLLQNTDAHK RAFHEIYQTR SVNGIPMPPD 

       490        500        510        520        530        540 
QLEDMAERFH FVSSTSELHL MKMEFLELKY RLLSLLVLAE SKLKSWIIKY GRRESVELLL 

       550        560        570        580        590        600 
QSYISFIENS KFFEQYEVTY QILKQTADIY VKAEGSVEEA ENVMKFMSEA TAQWRNLSVE 

       610        620        630        640        650        660 
VRSVRSMLEE VISNWDRYGD TVASLQAWLE DAEKMLSQSE HAKKDFFRNL PHWIQQHTAM 

       670        680        690        700        710        720 
NDAGNFLIET CDEIVSRDLK QQLLLLNGRW RELFMEVKQY ARADEMDRMK KEYIDVTTTL 

       730        740        750        760        770        780 
FGFATEAHRK LSEPLEVSFI NVKLLIQDLE DLEKRVPVMD AQYKMIAKKA HLFAKESPQE 

       790        800        810        820        830        840 
EANEMLTTMS KLKEQLSKVK ECCSPLLYEA QQLTVPLEEL ETQITSFYDS LGKINEILSV 

       850        860        870        880        890        900 
LEQEAQSSTL FKQKHQELLA SQENCKKSLT LIEKGSQSVQ KLVTSSQARK PWDHTKLQKQ 

       910        920        930        940        950        960 
IADVHHAFQS MIKKTGDWKK HVEANSRLMK KFEESRAELE KVLRVAQEGL EEKGDPEELL 

       970        980        990       1000       1010       1020 
RRHTEFFSQL DQRVLNAFLK ACDELTDILP EQEQQGLQEA VRKLHKQWKD LQGEAPYHLL 

      1030       1040       1050       1060       1070       1080 
HLKIAVEKDR FSAAVEECRA ELEQETKLAP QEGSEKIIKE HRVFFSDKGP HHLCEKRLQL 

      1090       1100       1110       1120       1130       1140 
IEELCGKLPV QDPVRDTCGA CHTALKELKA SIDNTYTMLV DDPDKWKDYT SRFSEFSSWV 

      1150       1160       1170       1180       1190       1200 
SAKKACLKKI KDEPIDTGNH DEVKHMVDEI RNDITKKGES LSWLKSRLKY LIDISSENEA 

      1210       1220       1230       1240       1250       1260 
QKRGDELAEL SSSFKALVAL LSEVEKLLSN FGECVQYKEI VKSSLEGLIS GPQESKEEAE 

      1270       1280       1290       1300       1310       1320 
MILDSKNLLE AQQLLLHHQQ KTKMISAKKR DLQEQMEQAQ QGGQAGPGQE ELRKLESTLT 

      1330       1340       1350       1360       1370       1380 
GLEQSRERQE RRIQVSLRKW ERFETNKETV VRYLFQTGSS HERFLSFSSL ESLSSELEQT 

      1390       1400       1410       1420       1430       1440 
KEFSKRTESI ATQAENLVKE AAELPLGPRN KRVLQRQAKS IKEQVTTLED TLEEDIKTME 

      1450       1460       1470       1480       1490       1500 
MVKSKWDHFG SNFETLSIWI LEKENELSSL EASASAADVQ ISQIKVTIQE IESKIDSIVG 

      1510       1520       1530       1540       1550       1560 
LEEEAQSFAQ FVTTGESARI KAKLTQIRRY WEELQEHARG LEGTILGHLS QQQKFEENLR 

      1570       1580       1590       1600       1610       1620 
KIRQSVSEFA ERLADPIKIC SSAAETYKVL QEHMDLCQAV ESLSSTVTMF SASAQKAVNR 

      1630       1640       1650       1660       1670       1680 
ESCTQEAAAL QQQYEEILHK AKEMQTALED LLARWQRLEK GLSPFLTWLE RCEAIASSPE 

      1690       1700       1710       1720       1730       1740 
KDISADRGKV ESELQLIQAL QNEVVSQASL YSNLLQLKEA LFSVASKEDV AVMKLQLEQL 

      1750       1760       1770       1780       1790       1800 
DERWGDLPQI ISKRMHFLQS VLAEHKQFDE LLFSFSVWIK QFLGELQRTS EINLRDHQVA 

      1810       1820       1830       1840       1850       1860 
LTRHKDHAAE IEKKRGEITH LQGHLSQLRS LGRAQDLHPL QSKVDDCFQL FEEASQVVER 

      1870       1880       1890       1900       1910       1920 
RKLALAQLAE FLQSHACMST LLYQLRQTVE ATKSMSKKQS DSLKTDLHSA IQDVKTLESS 

      1930       1940       1950       1960       1970       1980 
AISLDGTLTK AQCHLKSASP EERTSCRATT DQLSLEVERI QNLLGTKQSE ADALVALKEA 

      1990       2000       2010       2020       2030       2040 
FREQKEELLR SIEDIEERMD RERLKVPTRQ ALQHRLRVFN QLEDELNSHE HELCWLKDKA 

      2050       2060       2070       2080       2090       2100 
KQIAQKDVAF APEVDREING LEATWDDTRR QIHENQGQCC GLIDLVREYQ SLKSTVCNVL 

      2110       2120       2130       2140       2150       2160 
EDASNVVVMR ATIKDQGDLK WAFSKHETSR NEMNSKQKEL DSFTSKGKHL LSELKKIHSG 

      2170       2180       2190       2200       2210       2220 
DFSLVKTDME STLDKWLDVS ERIEENMDML RVSLSIWDDV LSRKDEIEGW SNSSLPKLAE 

      2230       2240       2250       2260       2270       2280 
NISNLNNSLR AEELLKELES EVKIKALKLE DLHSKINNLK ELTKNPETPT ELQFIEADLR 

      2290       2300       2310       2320       2330       2340 
QKLEHAKEIT EEARGTLKDF TAQRTQVERF VKDITAWLIN VEESLTRCAQ TETCEGLKKA 

      2350       2360       2370       2380       2390       2400 
KDIRKELQSQ QNSITSTQEE LNSLCRKHHS VELESLGRAM TGLIKKHEAT SQLCSQTQAR 

      2410       2420       2430       2440       2450       2460 
IQDSLEKHFS GSMKEFQEWF LGAKAAARES SNLTGDSQIL EARLHNLQGV LDSLSDGQSK 

      2470       2480       2490       2500       2510       2520 
LDVVTQEGQT LYAHLPKQIV SSIQEQITKA NEEFQAFLKQ CLKEKQALQD CVSELGSFED 

      2530       2540       2550       2560       2570       2580 
QHRKLNLWIH EMEERLKTEN LGESKHHISE KKNEVRKVEM FLGELLAARE SLDKLSQRGQ 

      2590       2600       2610       2620       2630       2640 
LLSEESHSAG KGGCRSTQLL TSYQSLLRVT KEKLRSCQLA LKEHEALEEA TQSMWARVKD 

      2650       2660       2670       2680       2690       2700 
VQDRLACAES TLGNKETLEG RLSQIQDILL MKGEGEVKLN LAIGKGDQAL RSSNKEGQQA 

      2710       2720       2730       2740       2750       2760 
IQDQLEMLKK AWAEAMNSAV HAQSTLESVI DQWNDYLEKK SQLEQWMESV DQRLEHPLQL 

      2770       2780       2790       2800       2810       2820 
QPGLKEKFSL LDHFQSIVSE AEDHTGALQQ LAAKSRELYQ KTQDESFKEA GQEELRTQFQ 

      2830       2840       2850       2860       2870       2880 
DIMTVAKEKM RTVEDLVKDH LMYLDAVQEF ADWLHSAKEE LHRWSDTSGD PSATQKKLLK 

      2890       2900       2910       2920       2930       2940 
IKELIDSREI GAGRLSRVES LAPAVKQNTA ASGCELLNSE MQALRADWRQ WEDCLFQTQS 

      2950       2960       2970       2980       2990       3000 
SLESLVSEMA LSEQEFFGQV TQLEQALEQF CTLLKTWAQQ LTLLEGKNSD EEILECWHKG 

      3010       3020       3030       3040       3050       3060 
REILDALQKA EPMTEDLKSQ LNELCRFSRD LSPYSEKVSG LIKEYNCLCL QASKGCQNKE 

      3070       3080       3090       3100       3110       3120 
QILQERFQKA SRGFQQWLVN AKITTAKCFD LPQNLSEVSS SLQKIQEFLS ESENGQHKLN 

      3130       3140       3150       3160       3170       3180 
TMLFKGELLS SLLTEEKAQA VQAKVLTAKE EWKSFHANLH QKESALENLK IQMKDFEVSA 

      3190       3200       3210       3220       3230       3240 
ELVQNWLSKT ERLVQESSNR LYDLPAKRRE QQKLQSVLEE IQCYEPQLHR LKEKARQLWE 

      3250       3260       3270       3280       3290       3300 
GQAASKSFVH RVSQLSSQYL ALSNVTKEKV SRLDRIIAEH NRFSQGVKEL QDWMSDAVHM 

      3310       3320       3330       3340       3350       3360 
LDSYCLPTSD KSVLDSRMLK LEALLSVRQE KEIQMKMVVT RGEYVLQSTS LEGSAAVQQQ 

      3370       3380       3390       3400       3410       3420 
LQAVKDMWES LLSAAIRCKS QLEGALSKWT SYQDDVRQFS SWMDSVEVSL TESEKQHTEL 

      3430       3440       3450       3460       3470       3480 
REKITALGKA KLLNEEVLSH SSLLETIEVK RAAMTEHYVT QLELQDLQER HQALKEKAKE 

      3490       3500       3510       3520       3530       3540 
AVTKLEKLVR LHQEYQRDLK AFESWLEQEQ EKLDRCSVHE GDTNAHETML RDLQELQVRC 

      3550       3560       3570       3580       3590       3600 
AEGQALLNSV LHTREDVIPS GLPQAEDRVL ESLRQDWQVY QHRLAEARMQ LNNVVNKLRL 

      3610       3620       3630       3640       3650       3660 
MEQKFQQADE WLKRMEEKIN FRSECQSSRS DKEIQLLQLK KWHEDLSAHR DEVEEVGTRA 

      3670       3680       3690       3700       3710       3720 
QGILDETHIS SRMGCQATQL TSRYQALLLQ VLEQIKFFEE ELQCLEETES SLSSYSDWYG 

      3730       3740       3750       3760       3770       3780 
STHKNFKNVA TKIDKVDESM MGKKLKTLEV LLKDMEKGHS LLKSAREKGE RAMKFLAEHE 

      3790       3800       3810       3820       3830       3840 
AEALRKEIHT YMEQLKNLTS TVRKECMSLE KGLHLAKEFS DKYKVLAQWM AEYQEILCTP 

      3850       3860       3870       3880       3890       3900 
EEPKMELYEK KAQLSKYKSL QQMVLSHEPS VTSVQEKSEA LLELVQDQSL KDKIQKLQSD 

      3910       3920       3930       3940       3950       3960 
FQDLCSRAKE RVFSLEAKVK DHEDYNTELQ EVEKWLLQMS GRLVAPDLLE MSSLETITQQ 

      3970       3980       3990       4000       4010       4020 
LAHHKAMMEE IAGFEDRLDN LKAKGDTLIG QCPEHLQAKQ KQTVQAHLQG TKDSYSAICS 

      4030       4040       4050       4060       4070       4080 
TAQRVYRSLE YELQKHVSSQ DTLQQCQAWI SAVQPDLKPS PQPPLSRAEA VKQVKHFRAL 

      4090       4100       4110       4120       4130       4140 
QEQARTYLDL LCSMCDLSNS SVKNTAKDIQ QTEQLIEQRL VQAQNLTQGW EEIKSLKAEL 

      4150       4160       4170       4180       4190       4200 
WIYLQDADQQ LQNMKRRHTE LEINIAQNMV MQVKDFIKQL QCKQVSVSTI VEKVDKLTKN 

      4210       4220       4230       4240       4250       4260 
QESPEHKEIT HLNDQWQDLC LQSDKLCAQR EQDLQRTSSY HDHMRVVEAF LEKFTTEWDS 

      4270       4280       4290       4300       4310       4320 
LARSNAESTA IHLEALKKLA LALQEEMYAI DDLKDCKQKL IEQLGLDDRE LVREQTSHLE 

      4330       4340       4350       4360       4370       4380 
QRWFQLQDLV KRKIQVSVTN LEELNVIQSR FQELMEWAEE QQPNIVEALK QSPPPGMAQH 

      4390       4400       4410       4420       4430       4440 
LLMDHLAICS ELEAKQVLLK SLMKDADRVM ADLGLNERKV IQKALSEAQK HVSCLSDLVG 

      4450       4460       4470       4480       4490       4500 
QRRKYLNKAL SEKTQFLMAV FQATSQIQQH ERKIVFREYI CLLPDDVSKQ VKTCKTAQAS 

      4510       4520       4530       4540       4550       4560 
LKTYQNEVTG LCAQGRELMK GITKQEQEEV LGKLQELQTV YDTVLQKCSH RLQELEKSLV 

      4570       4580       4590       4600       4610       4620 
SRKHFKEDFD KACHWLKQAD IVTFPEINLM NEKTELHAQL DKYQSILEQS PEYENLLLTL 

      4630       4640       4650       4660       4670       4680 
QTTGQAMLPS LNEVDHSYLS EKLSALPQQF NVIVALAKDK FYKTQEAILA RKEYTSLIEL 

      4690       4700       4710       4720       4730       4740 
TTQSLGDLED QFLKMRKMPS DLIVEESVSL QQSCSALLGE VVALGEAVNE LNQKKESFRS 

      4750       4760       4770       4780       4790       4800 
TGQPWQPEKM LQLATLYHRL KRQAEQRVSF LEDTTSVYKE HAQMCRQLES QLEVVKREQA 

      4810       4820       4830       4840       4850       4860 
KVNEETLPAE EKLKVYHSLA GSLQDSGILL KRVATHLEDL SPHLDPTAYE KAKSQVQSWQ 

      4870       4880       4890       4900       4910       4920 
EELKQMTSDV GELVTECESR MVQSIDFQTE MSRSLDWLRR VKAELSGPVC LDLSLQDIQE 

      4930       4940       4950       4960       4970       4980 
EIRKIQIHQE EVLSSLRIMS ALSHKEQEKF TKAKELISAD LEHTLAELQE LDGDVQEALR 

      4990       5000       5010       5020       5030       5040 
TRQATLTEIY SRCQRYYQVF QAANDWLDDA QEMLQLAGNG LDVESAEENL RSHMEFFKTE 

      5050       5060       5070       5080       5090       5100 
GQFHSNMEEL RGLVARLDPL IKATGKEELA QKMASLEKRS QGIIQESHTQ RDLLQRCMVQ 

      5110       5120       5130       5140       5150       5160 
WQEYQKAREG VIELMNDAEK KLSEFAVLKT SSIHEAEEKL SKHKALVSVV DSFHEKIVAL 

      5170       5180       5190       5200       5210       5220 
EEKASQLEQT GNDTSKATLS RSMTTVWQRW TRLRAVAQDQ EKILEDAVDE WKRLSAKVKE 

      5230       5240       5250       5260       5270       5280 
TTEVINQLQG RLPGSSTEKA SKAELMTLLE SHDTYLMDLE SQQLTLGVLQ QRALSMLQDR 

      5290       5300       5310       5320       5330       5340 
AFPGTEEEVP ILRAITALQD QCLNMQEKVK NHGKLVKQEL QEREAVETRI NSVKSWVQET 

      5350       5360       5370       5380       5390       5400 
KDYLGNPTIE IDTQLEELKR LLAEATSHQE SIEKIAEEQK NKYLGLYTVL PSEISLQLAE 

      5410       5420       5430       5440       5450       5460 
VALDLKIHDQ IQEKVQEIEE GKAMSQEFSC KIQKVTKDLT TILTKLKAKT DDLVHAKAEH 

      5470       5480       5490       5500       5510       5520 
KMLGEELDGC NSKLMELDAA IQTFSERHSQ LGQPLAKKIG KLTELHQQTI RQAENRLSKL 

      5530       5540       5550       5560       5570       5580 
NQALSHMEEY NEMLETVRKW IEKAKVLVHG NIAWNSASQL QEQYILHQTL LEESGEIDSD 

      5590       5600       5610       5620       5630       5640 
LEAMAEKVQH LANVYCTGKL SQQVTQFGRE MEELRQAIRV RLRNLQDAAK DMKKFEGELR 

      5650       5660       5670       5680       5690       5700 
NLQVALEQAQ TILTSPEVGR RSLKEQLCHR QHLLSEMESL KPKMQAVQLC QSALRIPEDV 

      5710       5720       5730       5740       5750       5760 
VASLPLCHAA LRLQEEASQL QHTAIQQCNI MQAKKHSLIF PPKEAVVQYE QYKQEMKHLQ 

      5770       5780       5790       5800       5810       5820 
QLIEEAHREI EDKPVATSNI QELQAQISLH EELAQKIKGY QEQIDSLNSK CKMLTMKAKH 

      5830       5840       5850       5860       5870       5880 
ATMLLTVTEV EGLAEGTEDL DRELHPTPSA HPSVVMMTAG RCHTLLSPVT EESGEEGTNS 

      5890       5900       5910       5920       5930       5940 
EISSPPACRS PSPVANTEAA VNQDIAYYQA LSAEGLQTDA ARIPPSAAVS QELYEPGLEP 

      5950       5960       5970       5980       5990       6000 
SATAKLGDLQ RSWETLKNVI SEKQRTLYEV LERQQKYQDS LQSISTKMEA MEMKLGESLE 

      6010       6020       6030       6040       6050       6060 
PSRSPESQMA EHQALMDEVQ MLQDEINGLQ VSLAEELVAE SQESDPAEQL ALQSTLTVLA 

      6070       6080       6090       6100       6110       6120 
ERMSTIRMKA AGKRQLLEEK LSDQLEEQRQ EQALQRYRCE ADELDHWLLN TKATLDVALG 

      6130       6140       6150       6160       6170       6180 
TSQEPMDMDA QLVDCQNMLV EIEQKVVALS QLSVHNENLL LEGKAHTKEE AEQLAVKLRL 

      6190       6200       6210       6220       6230       6240 
LKGSLGELQR ALHDRQLDMQ GVTQEKEEND VDFTDTQSPG VQEWLAQART TRTHQRQSSL 

      6250       6260       6270       6280       6290       6300 
QQQKEFEQEL AEQKSLLRSV ASRGEEILTQ HSTAEGSGGL GEKPDVLSQE LGIAEDQMRV 

      6310       6320       6330       6340       6350       6360 
KWESLHQEFS AKQKLLQNIL EQEQEQVLYS SPNRLLSGVL PFRGEAQTQD KTSVTSLLDG 

      6370       6380       6390       6400       6410       6420 
LSQAFGEASS QSGGTDRQSI HLEQKLYDGV SATSTWLNDV EERLFVATAP LPEETEACLF 

      6430       6440       6450       6460       6470       6480 
NQEALAKDIK EMSEEMDKNK NLFSQAFPED SDNRDVIEDT LGCLLGRLSL LDSVVDQRCH 

      6490       6500       6510       6520       6530       6540 
QMKERLQQIL RFQNDLKVLF TSLADSKYII LQKLANVFEQ PIVEQMQAIQ QAEEGLRDLE 

      6550       6560       6570       6580       6590       6600 
GGISELKRWA DKLQVEQSAV QELSKLQDMY DELLMTVSSR RSSLHQNLAL KSQYDKALQD 

      6610       6620       6630       6640       6650       6660 
LVDLLDTGQE KMTGDQKIIV CSKEEIQQLL GKHKEYFQGL ESHMILTEIL FRKIVGFAAV 

      6670       6680       6690       6700       6710       6720 
KETQFHTDCM AQASAVLKQA HKRGVELEYI LEMWSHLDEN RQELSRQLEV IENSIPSVGL 

      6730       6740       6750       6760       6770       6780 
VEESEDRLVE RTNLYQHLKS SLNEYQPKLY QALDDGKRLL MSVSCSELES QLNQLGEHWL 

      6790       6800       6810       6820       6830       6840 
SNTNKVSKEL HRLETILKHW TRYQSEAAAL NHWLQCAKDR LAFWTQQSVT VPQELEMVRD 

      6850       6860       6870       6880       6890       6900 
HLSAFLEFSK EVDAKSALKS SVTSTGNQLL RLKKVDTAAL RAELSRMDSQ WTDLLTGIPV 

      6910       6920       6930       6940       6950       6960 
VQEKLHQLQM DKLPSRHAIS EVMSWISLME SVILKDEEDI RNAIGYKAIH EYLQKYKGFK 

      6970       6980       6990       7000       7010       7020 
IDLNCKQLTA DFVNQSVLQI SSQDVESKRS DKTDFAEQLG AMNKSWQLLQ GRVGEKIQML 

      7030       7040       7050       7060       7070       7080 
EGLLESWSEY ENSVQSLKAW FANQERKLKE QHLLGDRNSV ENALKDCQEL EDLIKAKEKE 

      7090       7100       7110       7120       7130       7140 
VEKIEQNGLA LIQNKREEVS GSVMSTLQEL RQTWISLDRT VEQLKIQLTS ALGQWSNHKA 

      7150       7160       7170       7180       7190       7200 
ACDEINGHLM EARYSLSRFR LLTGSSEAVQ VQVDNLQNLH DELEKQEGGL QKFGSITNQL 

      7210       7220       7230       7240       7250       7260 
LKECHPPVAE TLSSTLQEVN MRWNNLLEEI AEQLHSSKAL LQLWQRYKDY SKQCASAIQR 

      7270       7280       7290       7300       7310       7320 
QEEQTSVLLK AATNKDIADD EVTKWIQDCN DLLKGLETVK DSLFILRELG EQLGQQVDVS 

      7330       7340       7350       7360       7370       7380 
AAAAIQCEQL CFSQRLGALE QALCKQQAVL QAGVVDYETF AKSLEALEVW MVEAEGILQG 

      7390       7400       7410       7420       7430       7440 
QDPTHSSDLS TIQERMEELK GQMLKFSSLA PDLDRLNELG YRLPLNDKEI KRMQNLNRHW 

      7450       7460       7470       7480       7490       7500 
SLTSSQTTER FSKLQSFLLQ HQTFLEKCET WMEFLVQTEH KLAVEISGNY QHLLEQQRAH 

      7510       7520       7530       7540       7550       7560 
ELFQAEMFSR QQILHSIIVD GQNLLEQGQV DDREEFSLKL TLLSNQWQGV IRRAQQRRGI 

      7570       7580       7590       7600       7610       7620 
IDSQIRQWQR YREMAEKLRK WLAEVSHLPL SGLGNIPVPL QQVRMLFDEV QFKEKVFLRQ 

      7630       7640       7650       7660       7670       7680 
QGSYILTVEA GKQLLLSADS GAEAALQAEL TDIQEKWKAA SMHLEEQKKK LAFLLKDWEK 

      7690       7700       7710       7720       7730       7740 
CERGIANSLE KLRMFKKRLS QPLPDHHEEL HAEQMRCKEL ENAVGRWTDD LTELMLVRDA 

      7750       7760       7770       7780       7790       7800 
LAVYLSAEDI SMLKERVELL QRQWEELCHQ VSLRRQQVSE RLNEWAVFSE KNKELCEWLT 

      7810       7820       7830       7840       7850       7860 
QMESKVSQNG DILIEEMIEK LKKDYQEEIA VAQENKIQLQ EMGERLAKAS HESKASEIQY 

      7870       7880       7890       7900       7910       7920 
KLSRVKDRWQ HLLDLMAARV KKLKETLVAV QQLDKNMGSL RTWLAHMESE LAKPIVYDSC 

      7930       7940       7950       7960       7970       7980 
NSEEIQRKLN EQQELQRDIE KHSTGVASVL NLCEVLLHDC DACATDAECD SIQQATRNLD 

      7990       8000       8010       8020       8030       8040 
RRWRNICAMS MERRLKIEET WRLWQKFLDD YSRFEDWLEV SERTAAFPSS SGVLYTVAKE 

      8050       8060       8070       8080       8090       8100 
ELKKFEAFQR QVHESLTQLE LINKQYRRLA RENRTDSACS LRQMVHGGNQ RWDDLQKRVT 

      8110       8120       8130       8140       8150       8160 
SILRRLKHFI SQREEFETAR DSILVWLTEM DLQLTNIEHF SECDVQAKIK QLKAFQQEIS 

      8170       8180       8190       8200       8210       8220 
LNHNKIEQII AQGEQLIEKS EPLDAAVIEE ELDELRRYCQ EVFGRVERYH KKLIRLPVRL 

      8230       8240       8250       8260       8270       8280 
PDDHDLSDRE LDLEDSTALS DLRWQDPSAD GMPSPQPSSN PSLSLPQPLR SERSGRDTPA 

      8290       8300       8310       8320       8330       8340 
SVDSIPLEWD HDYDLSRDLE SASRTLPSED EEGEEDKEFY LRGAVGLSGD PSSLESQMRQ 

      8350       8360       8370       8380       8390       8400 
LDKALDDSRF QIQQTANILR SKTPTGPDLD TSYKGYMKLL GECSGSIDSV RRLEHKLAEE 

      8410       8420       8430       8440       8450       8460 
ESFPGFVNLN STETQTAGVI DRWELLQAQA MSKELRMKQN LQKWQQFNSD LNNIWAWLGE 

      8470       8480       8490       8500       8510       8520 
TEEELDRLQH LALSTDIHTI ESHIKKLKEL QKAVDHRKAI ILSINLCSSE FTQADSKESH 

      8530       8540       8550       8560       8570       8580 
DLQDRLSQMN GRWDRVCSLL EDWRGLLQDA LMQCQEFHEM SHALLLMLEN IDRRKNEIVP 

      8590       8600       8610       8620       8630       8640 
IDSTLDPETL QDHHKQLMQI KQELLKSQLR VASLQDMSRQ LLVNAEGSDC LEAKEKVHVI 

      8650       8660       8670       8680       8690       8700 
GNRLKLLLKE VSHHIKDLEK LLDMSSSQQD LSSWSSADEL DTSGSVSPTS GRSTPNRQKS 

      8710       8720       8730       8740       8750       8760 
PRGKCSLSQP GPSVSSPKSR STRDGSDSSR SDPRPERVGR AFLFRILRAA LPFQLLLLLL 

      8770       8780       8790 
IGLTCLVPMS EKDYSCALSN NFARSFHPML RYTNGPPPL 

« Hide

Isoform 2 [UniParc].

Checksum: 6ED3F1A381AACC9A
Show »

FASTA972111,334
Isoform 3 (Syne-1A) [UniParc].

Checksum: 40ABE338F614825E
Show »

FASTA949108,779
Isoform 4 (Syne-1B) [UniParc].

Checksum: 08970A024A161721
Show »

FASTA8,7971,009,670
Isoform 5 (Enaptin-165) [UniParc].

Checksum: 0D4C7DA8ADAE612F
Show »

FASTA1,431165,244

References

« Hide 'large scale' references
[1]"Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction."
Apel E.D., Lewis R.M., Grady R.M., Sanes J.R.
J. Biol. Chem. 275:31986-31995(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [MRNA] OF 6808-8799 (ISOFORM 4), INTERACTION WITH MUSK, SUBCELLULAR LOCATION.
[2]"Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton."
Padmakumar V.C., Abraham S., Braune S., Noegel A.A., Tunggal B., Karakesisoglou I., Korenbaum E.
Exp. Cell Res. 295:330-339(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5), TISSUE SPECIFICITY, ACTIN-BINDING, SUBCELLULAR LOCATION.
Strain: BALB/c.
Tissue: Brain.
[3]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Strain: C57BL/6J.
Tissue: Vagina.
[4]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[5]"Nuclear membrane proteins with potential disease links found by subtractive proteomics."
Schirmer E.C., Florens L., Guan T., Yates J.R. III, Gerace L.
Science 301:1380-1382(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
[6]"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-8308, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Brain.
[7]"Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton."
Dawe H.R., Adams M., Wheway G., Szymanska K., Logan C.V., Noegel A.A., Gull K., Johnson C.A.
J. Cell Sci. 122:2716-2726(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[8]"SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice."
Lei K., Zhang X., Ding X., Guo X., Chen M., Zhu B., Xu T., Zhuang Y., Xu R., Han M.
Proc. Natl. Acad. Sci. U.S.A. 106:10207-10212(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
[9]"Cytoskeletal interactions at the nuclear envelope mediated by nesprins."
Taranum S., Sur I., Muller R., Lu W., Rashmi R.N., Munck M., Neumann S., Karakesisoglou I., Noegel A.A.
Int. J. Cell Biol. 2012:736524-736524(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: SELF-ASSOCIATION, INTERACTION WITH SYNE3, TISSUE SPECIFICITY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF281869 mRNA. Translation: AAG24392.1.
AF281870 mRNA. Translation: AAG24393.1. Frameshift.
AF535143 mRNA. Translation: AAN03487.1.
AK036828 mRNA. Translation: BAC29595.1.
AC156392 Genomic DNA. No translation available.
AC156393 Genomic DNA. No translation available.
AC157020 Genomic DNA. No translation available.
AC159748 Genomic DNA. No translation available.
AC161829 Genomic DNA. No translation available.
AC162381 Genomic DNA. No translation available.
AC162385 Genomic DNA. No translation available.
CCDSCCDS56679.1. [Q6ZWR6-3]
CCDS56680.1. [Q6ZWR6-5]
RefSeqNP_001073154.1. NM_001079686.1.
UniGeneMm.331626.

3D structure databases

ProteinModelPortalQ6ZWR6.
SMRQ6ZWR6. Positions 23-283, 997-1042.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid211015. 1 interaction.
STRING10090.ENSMUSP00000051825.

PTM databases

PhosphoSiteQ6ZWR6.

Proteomic databases

MaxQBQ6ZWR6.
PaxDbQ6ZWR6.
PRIDEQ6ZWR6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000041639; ENSMUSP00000039440; ENSMUSG00000096054. [Q6ZWR6-5]
ENSMUST00000095899; ENSMUSP00000093587; ENSMUSG00000019769. [Q6ZWR6-3]
GeneID64009.
KEGGmmu:64009.
UCSCuc007egn.1. mouse. [Q6ZWR6-5]
uc007egt.2. mouse. [Q6ZWR6-2]

Organism-specific databases

CTD23345.
MGIMGI:1927152. Syne1.

Phylogenomic databases

eggNOGCOG5069.
GeneTreeENSGT00750000117361.
HOGENOMHOG000120125.
HOVERGENHBG106534.
InParanoidQ9ERT7.
OMACATESEC.
OrthoDBEOG72JWF7.
PhylomeDBQ6ZWR6.
TreeFamTF317709.
TF337116.

Enzyme and pathway databases

ReactomeREACT_188804. Cell Cycle.
REACT_200794. Mus musculus biological processes.

Gene expression databases

ArrayExpressQ6ZWR6.
BgeeQ6ZWR6.
GenevestigatorQ6ZWR6.

Family and domain databases

Gene3D1.10.418.10. 2 hits.
InterProIPR001589. Actinin_actin-bd_CS.
IPR001715. CH-domain.
IPR012315. KASH.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
[Graphical view]
PfamPF00307. CH. 2 hits.
PF10541. KASH. 1 hit.
PF00435. Spectrin. 10 hits.
[Graphical view]
SMARTSM00033. CH. 2 hits.
SM00150. SPEC. 42 hits.
[Graphical view]
SUPFAMSSF47576. SSF47576. 2 hits.
PROSITEPS00019. ACTININ_1. 1 hit.
PS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.
PS51049. KASH. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSSYNE1. mouse.
NextBio319851.
PROQ6ZWR6.
SOURCESearch...

Entry information

Entry nameSYNE1_MOUSE
AccessionPrimary (citable) accession number: Q6ZWR6
Secondary accession number(s): Q8K3T7, Q9ERT7, Q9ERT8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: March 23, 2010
Last modified: July 9, 2014
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot