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Protein
Submitted name:

Nesprin-1

Gene

Syne1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Nesprin-1Imported
Gene namesi
Name:Syne1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1927152. Syne1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiQ6ZWR5.
PRIDEiQ6ZWR5.

Expressioni

Gene expression databases

GenevisibleiQ6ZWR5. MM.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 134Calponin-homology (CH)InterPro annotationAdd BLAST108
Domaini178 – 283Calponin-homology (CH)InterPro annotationAdd BLAST106

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0516. Eukaryota.
COG5069. LUCA.
GeneTreeiENSGT00760000118813.

Family and domain databases

CDDicd00014. CH. 2 hits.
Gene3Di1.10.418.10. 2 hits.
InterProiView protein in InterPro
IPR001589. Actinin_actin-bd_CS.
IPR001715. CH-domain.
IPR030265. SYNE1.
PANTHERiPTHR11915:SF362. PTHR11915:SF362. 1 hit.
PfamiView protein in Pfam
PF00307. CH. 2 hits.
SMARTiView protein in SMART
SM00033. CH. 2 hits.
SUPFAMiSSF47576. SSF47576. 2 hits.
PROSITEiView protein in PROSITE
PS00019. ACTININ_1. 1 hit.
PS00020. ACTININ_2. 1 hit.
PS50021. CH. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q6ZWR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATSRASSRS HRDITNVMQR LQDEQEIVQK RTFTKWINSH LAKRKPPMVV
60 70 80 90 100
DDLFEDMKDG IKLLALLEVL SGQKLPCEQG HRVKRIHAVA NIGTALKFLE
110 120 130 140 150
GRKIKLVNIN ATDIADGRPS IVLGLMWTII LYFQIEELTS NLPQLQSLSS
160 170 180 190 200
SASSVDSMVS TETASPPSKR KVAAKIQGNA KKTLLKWVQH TAGKQMGIEV
210 220 230 240 250
KDFGKSWRTG LAFHSVIHAI QPELVDLEKV KTRSNRENLE DAFTIAETQL
260 270 280 290 300
GIPRLLDPED VDVDKPDEKS IMTYVAQFLT QYPDIHGAGC DGQEDDRDDR
310 320 330 340 350
LILKETKVWI EQFERDFTRA QMTESSLQDK YQAFKHFRVQ YEMKRKQVEH
360 370 380 390 400
IIQPLQRDGK LTLDQALVKQ CWERVSSRLF DWHIQLDKSL PAPLGTIGAW
410 420 430 440 450
LYRAEVALRE EITIQQVHEE TANTIQRKLE QHKDLLQNTD AHKRAFHEIY
460 470 480 490 500
QTRSVNGIPM PPDQLEDMAE RFHFVSSTSE LHLMKMEFLE LKYRLLSLLV
510 520 530 540 550
LAESKLKSWI IKYGRRESVE LLLQSYISFI ENSKFFEQYE VTYQILKQTA
560 570 580 590 600
DIYVKAEGSV EEAENVMKFM SEATAQWRNL SVEVRSVRSM LEEVISNWDR
610
YGDTVASLQA WLEDA
Length:615
Mass (Da):70,947
Last modified:July 19, 2004 - v1
Checksum:i10B1DA9E49B66AB9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei615Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC156392 Genomic DNA. No translation available.
AC156393 Genomic DNA. No translation available.
AC157020 Genomic DNA. No translation available.
AC159748 Genomic DNA. No translation available.
AC161829 Genomic DNA. No translation available.
AC162381 Genomic DNA. No translation available.
AC162385 Genomic DNA. No translation available.
AK039486 mRNA. Translation: BAC30365.1.
RefSeqiNP_700448.2. NM_153399.2.
UniGeneiMm.331626.

Genome annotation databases

EnsembliENSMUST00000214945; ENSMUSP00000149011; ENSMUSG00000096054.
GeneIDi64009.
UCSCiuc007egm.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ6ZWR5_MOUSE
AccessioniPrimary (citable) accession number: Q6ZWR5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: September 27, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported