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Q6ZVX9

- PAQR9_HUMAN

UniProt

Q6ZVX9 - PAQR9_HUMAN

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Protein

Progestin and adipoQ receptor family member 9

Gene
PAQR9
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. receptor activity Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Names & Taxonomyi

Protein namesi
Recommended name:
Progestin and adipoQ receptor family member 9
Alternative name(s):
Progestin and adipoQ receptor family member IX
Gene namesi
Name:PAQR9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:30131. PAQR9.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 8686Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei87 – 10721Helical; Reviewed predictionAdd
BLAST
Topological domaini108 – 1169Extracellular Reviewed prediction
Transmembranei117 – 13721Helical; Reviewed predictionAdd
BLAST
Topological domaini138 – 16225Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei163 – 18321Helical; Reviewed predictionAdd
BLAST
Topological domaini184 – 20522Extracellular Reviewed predictionAdd
BLAST
Transmembranei206 – 22621Helical; Reviewed predictionAdd
BLAST
Topological domaini227 – 24317Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei244 – 26421Helical; Reviewed predictionAdd
BLAST
Topological domaini265 – 30137Extracellular Reviewed predictionAdd
BLAST
Transmembranei302 – 32221Helical; Reviewed predictionAdd
BLAST
Topological domaini323 – 34321Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei344 – 36421Helical; Reviewed predictionAdd
BLAST
Topological domaini365 – 37713Extracellular Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134880790.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377Progestin and adipoQ receptor family member 9PRO_0000218852Add
BLAST

Proteomic databases

PaxDbiQ6ZVX9.
PRIDEiQ6ZVX9.

Expressioni

Tissue specificityi

Expression levels vary widely in a range of tissues.1 Publication

Gene expression databases

ArrayExpressiQ6ZVX9.
BgeeiQ6ZVX9.
CleanExiHS_PAQR9.
GenevestigatoriQ6ZVX9.

Organism-specific databases

HPAiHPA052798.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000341564.

Structurei

3D structure databases

ProteinModelPortaliQ6ZVX9.

Family & Domainsi

Sequence similaritiesi

Belongs to the ADIPOR family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG241923.
HOGENOMiHOG000115439.
HOVERGENiHBG053506.
InParanoidiQ6ZVX9.
OMAiMTPYVQQ.
PhylomeDBiQ6ZVX9.
TreeFamiTF319738.

Family and domain databases

InterProiIPR004254. HlyIII-related.
[Graphical view]
PANTHERiPTHR20855. PTHR20855. 1 hit.
PfamiPF03006. HlyIII. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZVX9-1 [UniParc]FASTAAdd to Basket

« Hide

MPRRLQPRGA GTKGPPAPAP AASGAARNSH SAASRDPPAS AKPLLRWDEV    50
PDDFVECFIL SGYRRLPCTA QECLASVLKP TNETLNFWTH FIPLLLFLSK 100
FCRLFFLSGG DVPFHHPWLL PLWCYASGVL LTFAMSCTAH VFSCLSLRLR 150
AAFFYLDYAS ISYYGFGSTV AYYYYLLPGL SLLDARVMTP YLQQRLGWHV 200
DCTRLIAAYR ALVLPVAFVL AVACTVACCK SRTDWCTYPF ALRTFVFVMP 250
LSMACPIMLE SWLFDLRGEN PTLFVHFYRR YFWLVVAAFF NVSKIPERIQ 300
PGLFDIIGHS HQLFHIFTFL SIYDQVYYVE EGLRQFLQAP PAAPTFSGTV 350
GYMLLLVVCL GLVIRKFLNS SEFCSKK 377
Length:377
Mass (Da):42,692
Last modified:July 5, 2004 - v1
Checksum:iC1708C12C5C5A7C5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY424287 mRNA. Translation: AAR08375.1.
AK123932 mRNA. Translation: BAC85729.1.
BC118666 mRNA. Translation: AAI18667.1.
BC122527 mRNA. Translation: AAI22528.1.
CCDSiCCDS3128.1.
RefSeqiNP_940906.1. NM_198504.2.
UniGeneiHs.408385.
Hs.656111.

Genome annotation databases

EnsembliENST00000340634; ENSP00000341564; ENSG00000188582.
GeneIDi344838.
KEGGihsa:344838.
UCSCiuc003evg.3. human.

Polymorphism databases

DMDMi51701778.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY424287 mRNA. Translation: AAR08375.1 .
AK123932 mRNA. Translation: BAC85729.1 .
BC118666 mRNA. Translation: AAI18667.1 .
BC122527 mRNA. Translation: AAI22528.1 .
CCDSi CCDS3128.1.
RefSeqi NP_940906.1. NM_198504.2.
UniGenei Hs.408385.
Hs.656111.

3D structure databases

ProteinModelPortali Q6ZVX9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000341564.

Polymorphism databases

DMDMi 51701778.

Proteomic databases

PaxDbi Q6ZVX9.
PRIDEi Q6ZVX9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000340634 ; ENSP00000341564 ; ENSG00000188582 .
GeneIDi 344838.
KEGGi hsa:344838.
UCSCi uc003evg.3. human.

Organism-specific databases

CTDi 344838.
GeneCardsi GC03M142668.
HGNCi HGNC:30131. PAQR9.
HPAi HPA052798.
MIMi 614580. gene.
neXtProti NX_Q6ZVX9.
PharmGKBi PA134880790.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG241923.
HOGENOMi HOG000115439.
HOVERGENi HBG053506.
InParanoidi Q6ZVX9.
OMAi MTPYVQQ.
PhylomeDBi Q6ZVX9.
TreeFami TF319738.

Miscellaneous databases

GenomeRNAii 344838.
NextBioi 98775.
PROi Q6ZVX9.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q6ZVX9.
Bgeei Q6ZVX9.
CleanExi HS_PAQR9.
Genevestigatori Q6ZVX9.

Family and domain databases

InterProi IPR004254. HlyIII-related.
[Graphical view ]
PANTHERi PTHR20855. PTHR20855. 1 hit.
Pfami PF03006. HlyIII. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif."
    Tang Y.T., Hu T., Arterburn M., Boyle B., Bright J.M., Emtage P.C., Funk W.D.
    J. Mol. Evol. 61:372-380(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Pericardium.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiPAQR9_HUMAN
AccessioniPrimary (citable) accession number: Q6ZVX9
Secondary accession number(s): Q147T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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