Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6ZVX9

- PAQR9_HUMAN

UniProt

Q6ZVX9 - PAQR9_HUMAN

Protein

Progestin and adipoQ receptor family member 9

Gene

PAQR9

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. receptor activity Source: RefGenome

    Keywords - Molecular functioni

    Receptor

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Progestin and adipoQ receptor family member 9
    Alternative name(s):
    Progestin and adipoQ receptor family member IX
    Gene namesi
    Name:PAQR9
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:30131. PAQR9.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134880790.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 377377Progestin and adipoQ receptor family member 9PRO_0000218852Add
    BLAST

    Proteomic databases

    PaxDbiQ6ZVX9.
    PRIDEiQ6ZVX9.

    Expressioni

    Tissue specificityi

    Expression levels vary widely in a range of tissues.1 Publication

    Gene expression databases

    ArrayExpressiQ6ZVX9.
    BgeeiQ6ZVX9.
    CleanExiHS_PAQR9.
    GenevestigatoriQ6ZVX9.

    Organism-specific databases

    HPAiHPA052798.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000341564.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6ZVX9.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 8686CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini108 – 1169ExtracellularSequence Analysis
    Topological domaini138 – 16225CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini184 – 20522ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini227 – 24317CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini265 – 30137ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini323 – 34321CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini365 – 37713ExtracellularSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei87 – 10721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei117 – 13721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei163 – 18321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei206 – 22621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei244 – 26421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei302 – 32221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei344 – 36421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ADIPOR family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG241923.
    HOGENOMiHOG000115439.
    HOVERGENiHBG053506.
    InParanoidiQ6ZVX9.
    OMAiMTPYVQQ.
    PhylomeDBiQ6ZVX9.
    TreeFamiTF319738.

    Family and domain databases

    InterProiIPR004254. HlyIII-related.
    [Graphical view]
    PANTHERiPTHR20855. PTHR20855. 1 hit.
    PfamiPF03006. HlyIII. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6ZVX9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRRLQPRGA GTKGPPAPAP AASGAARNSH SAASRDPPAS AKPLLRWDEV    50
    PDDFVECFIL SGYRRLPCTA QECLASVLKP TNETLNFWTH FIPLLLFLSK 100
    FCRLFFLSGG DVPFHHPWLL PLWCYASGVL LTFAMSCTAH VFSCLSLRLR 150
    AAFFYLDYAS ISYYGFGSTV AYYYYLLPGL SLLDARVMTP YLQQRLGWHV 200
    DCTRLIAAYR ALVLPVAFVL AVACTVACCK SRTDWCTYPF ALRTFVFVMP 250
    LSMACPIMLE SWLFDLRGEN PTLFVHFYRR YFWLVVAAFF NVSKIPERIQ 300
    PGLFDIIGHS HQLFHIFTFL SIYDQVYYVE EGLRQFLQAP PAAPTFSGTV 350
    GYMLLLVVCL GLVIRKFLNS SEFCSKK 377
    Length:377
    Mass (Da):42,692
    Last modified:July 5, 2004 - v1
    Checksum:iC1708C12C5C5A7C5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY424287 mRNA. Translation: AAR08375.1.
    AK123932 mRNA. Translation: BAC85729.1.
    BC118666 mRNA. Translation: AAI18667.1.
    BC122527 mRNA. Translation: AAI22528.1.
    CCDSiCCDS3128.1.
    RefSeqiNP_940906.1. NM_198504.2.
    UniGeneiHs.408385.
    Hs.656111.

    Genome annotation databases

    EnsembliENST00000340634; ENSP00000341564; ENSG00000188582.
    GeneIDi344838.
    KEGGihsa:344838.
    UCSCiuc003evg.3. human.

    Polymorphism databases

    DMDMi51701778.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY424287 mRNA. Translation: AAR08375.1 .
    AK123932 mRNA. Translation: BAC85729.1 .
    BC118666 mRNA. Translation: AAI18667.1 .
    BC122527 mRNA. Translation: AAI22528.1 .
    CCDSi CCDS3128.1.
    RefSeqi NP_940906.1. NM_198504.2.
    UniGenei Hs.408385.
    Hs.656111.

    3D structure databases

    ProteinModelPortali Q6ZVX9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000341564.

    Polymorphism databases

    DMDMi 51701778.

    Proteomic databases

    PaxDbi Q6ZVX9.
    PRIDEi Q6ZVX9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000340634 ; ENSP00000341564 ; ENSG00000188582 .
    GeneIDi 344838.
    KEGGi hsa:344838.
    UCSCi uc003evg.3. human.

    Organism-specific databases

    CTDi 344838.
    GeneCardsi GC03M142668.
    HGNCi HGNC:30131. PAQR9.
    HPAi HPA052798.
    MIMi 614580. gene.
    neXtProti NX_Q6ZVX9.
    PharmGKBi PA134880790.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG241923.
    HOGENOMi HOG000115439.
    HOVERGENi HBG053506.
    InParanoidi Q6ZVX9.
    OMAi MTPYVQQ.
    PhylomeDBi Q6ZVX9.
    TreeFami TF319738.

    Miscellaneous databases

    GenomeRNAii 344838.
    NextBioi 98775.
    PROi Q6ZVX9.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q6ZVX9.
    Bgeei Q6ZVX9.
    CleanExi HS_PAQR9.
    Genevestigatori Q6ZVX9.

    Family and domain databases

    InterProi IPR004254. HlyIII-related.
    [Graphical view ]
    PANTHERi PTHR20855. PTHR20855. 1 hit.
    Pfami PF03006. HlyIII. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif."
      Tang Y.T., Hu T., Arterburn M., Boyle B., Bright J.M., Emtage P.C., Funk W.D.
      J. Mol. Evol. 61:372-380(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Pericardium.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiPAQR9_HUMAN
    AccessioniPrimary (citable) accession number: Q6ZVX9
    Secondary accession number(s): Q147T6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 31, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3