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Protein

Putative protein SEM1, isoform 2

Gene

SEM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein SEM1, isoform 2Combined sources
Gene namesi
Name:SEM1Imported
Synonyms:C7orf76
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000127922.9.
HGNCiHGNC:10845. SEM1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000127922.

Polymorphism and mutation databases

BioMutaiC7orf76.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003190351 – 128Putative protein SEM1, isoform 2Add BLAST128

Proteomic databases

PaxDbiQ6ZVN7.
PRIDEiQ6ZVN7.

Expressioni

Gene expression databases

BgeeiENSG00000127922.
ExpressionAtlasiQ6ZVN7. baseline and differential.

Organism-specific databases

HPAiHPA020429.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000349114.

Structurei

3D structure databases

ProteinModelPortaliQ6ZVN7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410JIWW. Eukaryota.
ENOG41115YD. LUCA.
GeneTreeiENSGT00390000002695.
HOGENOMiHOG000155551.
HOVERGENiHBG106733.
InParanoidiQ6ZVN7.
KOiK10881.
OrthoDBiEOG091G0X0S.
PhylomeDBiQ6ZVN7.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative promoter usage. AlignAdd to basket

Isoform 2 (identifier: Q6ZVN7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MYCQDSNICA VFAVQGGKVG RKHGIKRGRR PSIRSPAQRA RGPWIHESKH
60 70 80 90 100
PAFAKQQINL EMPNSRATTE LAWVCSSTSR KKKWARSLTL STAPLSPPPS
110 120
LVHCEDCSCL PGCHSGDLYN LAPAERTC
Length:128
Mass (Da):14,085
Last modified:February 26, 2008 - v2
Checksum:i168AB7945F5ADAB8
GO
Isoform 1 (identifier: P60896-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P60896.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:70
Mass (Da):8,278
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti86R → G in BAC85824 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124274 mRNA. Translation: BAC85824.1.
AC092031 Genomic DNA. No translation available.
RefSeqiNP_001188379.1. NM_001201450.1. [Q6ZVN7-1]
NP_001188380.1. NM_001201451.1.
UniGeneiHs.489201.
Hs.729869.
Hs.734935.

Genome annotation databases

EnsembliENST00000356686; ENSP00000349114; ENSG00000127922. [Q6ZVN7-1]
GeneIDi7979.
KEGGihsa:7979.
UCSCiuc064fom.1. human. [Q6ZVN7-1]

Keywords - Coding sequence diversityi

Alternative promoter usage

Similar proteinsi

Entry informationi

Entry nameiSEML_HUMAN
AccessioniPrimary (citable) accession number: Q6ZVN7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: October 25, 2017
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM