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Protein

Putative protein SEM1, isoform 2

Gene

SEM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein SEM1, isoform 2Combined sources
Gene namesi
Name:SEM1Imported
Synonyms:C7orf76
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000127922.9
HGNCiHGNC:10845 SEM1
neXtProtiNX_Q6ZVN7

Pathology & Biotechi

Organism-specific databases

MalaCardsiSEM1
OpenTargetsiENSG00000127922

Polymorphism and mutation databases

BioMutaiC7orf76

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003190351 – 128Putative protein SEM1, isoform 2Add BLAST128

Proteomic databases

PaxDbiQ6ZVN7
PRIDEiQ6ZVN7

Expressioni

Gene expression databases

BgeeiENSG00000127922
ExpressionAtlasiQ6ZVN7 baseline and differential

Organism-specific databases

HPAiHPA020429

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000349114

Structurei

3D structure databases

ProteinModelPortaliQ6ZVN7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410JIWW Eukaryota
ENOG41115YD LUCA
GeneTreeiENSGT00390000002695
HOGENOMiHOG000155551
HOVERGENiHBG106733
InParanoidiQ6ZVN7
KOiK10881
OrthoDBiEOG091G0X0S
PhylomeDBiQ6ZVN7

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative promoter usage. AlignAdd to basket

Isoform 2 (identifier: Q6ZVN7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MYCQDSNICA VFAVQGGKVG RKHGIKRGRR PSIRSPAQRA RGPWIHESKH
60 70 80 90 100
PAFAKQQINL EMPNSRATTE LAWVCSSTSR KKKWARSLTL STAPLSPPPS
110 120
LVHCEDCSCL PGCHSGDLYN LAPAERTC
Length:128
Mass (Da):14,085
Last modified:February 26, 2008 - v2
Checksum:i168AB7945F5ADAB8
GO
Isoform 1 (identifier: P60896-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P60896.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:70
Mass (Da):8,278
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti86R → G in BAC85824 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK124274 mRNA Translation: BAC85824.1
AC092031 Genomic DNA No translation available.
RefSeqiNP_001188379.1, NM_001201450.1 [Q6ZVN7-1]
NP_001188380.1, NM_001201451.1
UniGeneiHs.489201
Hs.729869
Hs.734935

Genome annotation databases

EnsembliENST00000356686; ENSP00000349114; ENSG00000127922 [Q6ZVN7-1]
GeneIDi7979
KEGGihsa:7979
UCSCiuc064fom.1 human [Q6ZVN7-1]

Keywords - Coding sequence diversityi

Alternative promoter usage

Similar proteinsi

Entry informationi

Entry nameiSEML_HUMAN
AccessioniPrimary (citable) accession number: Q6ZVN7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: May 23, 2018
This is version 79 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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