Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6ZUM4

- RHG27_HUMAN

UniProt

Q6ZUM4 - RHG27_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Rho GTPase-activating protein 27

Gene

ARHGAP27

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).By similarity

GO - Molecular functioni

  1. Rac GTPase activator activity Source: HGNC
  2. SH3 domain binding Source: HGNC

GO - Biological processi

  1. positive regulation of Cdc42 GTPase activity Source: HGNC
  2. positive regulation of Rac GTPase activity Source: GOC
  3. receptor-mediated endocytosis Source: HGNC
  4. signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GTPase activation

Keywords - Biological processi

Endocytosis

Enzyme and pathway databases

SignaLinkiQ6ZUM4.

Names & Taxonomyi

Protein namesi
Recommended name:
Rho GTPase-activating protein 27
Alternative name(s):
CIN85-associated multi-domain-containing Rho GTPase-activating protein 1
Rho-type GTPase-activating protein 27
SH3 domain-containing protein 20
Gene namesi
Name:ARHGAP27
Synonyms:CAMGAP1, SH3D20
ORF Names:PP905
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:31813. ARHGAP27.

Subcellular locationi

Cytoplasm By similarity. Membrane By similarity; Peripheral membrane protein By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. intracellular Source: HGNC
  3. membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134873327.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 889889Rho GTPase-activating protein 27PRO_0000317578Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei216 – 2161PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ6ZUM4.
PaxDbiQ6ZUM4.
PRIDEiQ6ZUM4.

PTM databases

PhosphoSiteiQ6ZUM4.

Expressioni

Tissue specificityi

Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer.1 Publication

Gene expression databases

BgeeiQ6ZUM4.
CleanExiHS_ARHGAP27.
ExpressionAtlasiQ6ZUM4. baseline and differential.
GenevestigatoriQ6ZUM4.

Organism-specific databases

HPAiHPA023919.

Interactioni

Subunit structurei

Interacts with SH3KBP1/CIN85.By similarity

Protein-protein interaction databases

BioGridi128369. 4 interactions.
IntActiQ6ZUM4. 1 interaction.
MINTiMINT-5006179.
STRINGi9606.ENSP00000366121.

Structurei

Secondary structure

1
889
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi499 – 51012Combined sources
Beta strandi521 – 5288Combined sources
Beta strandi531 – 5366Combined sources
Helixi549 – 5524Combined sources
Beta strandi554 – 5607Combined sources
Beta strandi565 – 5684Combined sources
Helixi571 – 5733Combined sources
Beta strandi575 – 5839Combined sources
Beta strandi589 – 5935Combined sources
Helixi597 – 61115Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3PP2X-ray1.42A/B491-613[»]
ProteinModelPortaliQ6ZUM4.
SMRiQ6ZUM4. Positions 10-67, 498-612, 678-886.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 6962SH3PROSITE-ProRule annotationAdd
BLAST
Domaini246 – 28035WW 1PROSITE-ProRule annotationAdd
BLAST
Domaini299 – 33335WW 2PROSITE-ProRule annotationAdd
BLAST
Domaini411 – 44434WW 3PROSITE-ProRule annotationAdd
BLAST
Domaini496 – 612117PHPROSITE-ProRule annotationAdd
BLAST
Domaini697 – 886190Rho-GAPPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 PH domain.PROSITE-ProRule annotation
Contains 1 Rho-GAP domain.PROSITE-ProRule annotation
Contains 1 SH3 domain.PROSITE-ProRule annotation
Contains 3 WW domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, SH3 domain

Phylogenomic databases

eggNOGiNOG279563.
GeneTreeiENSGT00760000118882.
HOVERGENiHBG005328.
InParanoidiQ6ZUM4.
OMAiTPEYTVD.
PhylomeDBiQ6ZUM4.
TreeFamiTF329345.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR011047. Quinonprotein_ADH-like_supfam.
IPR015767. Rho_GTPase_act.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR001452. SH3_domain.
IPR001202. WW_dom.
[Graphical view]
PANTHERiPTHR23181. PTHR23181. 1 hit.
PfamiPF00169. PH. 1 hit.
PF00620. RhoGAP. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00324. RhoGAP. 1 hit.
SM00326. SH3. 1 hit.
SM00456. WW. 3 hits.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
SSF50044. SSF50044. 1 hit.
SSF50998. SSF50998. 1 hit.
SSF51045. SSF51045. 2 hits.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS50238. RHOGAP. 1 hit.
PS50002. SH3. 1 hit.
PS50020. WW_DOMAIN_2. 3 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6ZUM4-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAADVVGDVY VLVEHPFEYT GKDGRRVAIR PNERYRLLRR STEHWWHVRR
60 70 80 90 100
EPGGRPFYLP AQYVRELPAL GNPAAAAPPG PHPSPAAPEP LAYDYRFVSA
110 120 130 140 150
AATAGPDGAP EESGGRASSL CGPAQRGAAT QRSSLAPGLP ACLYLRPAAP
160 170 180 190 200
VRPAQSLNDL ACAAVSPPAG LLGSSGSFKA CSVAGSWVCP RPLARSDSEN
210 220 230 240 250
VYEVIQDLHV PPPEESAEQV DDPPEPVYAN IERQPRATSP GAAAAPLPSP
260 270 280 290 300
VWETHTDAGT GRPYYYNPDT GVTTWESPFE AAEGAASPAT SPASVDSHVS
310 320 330 340 350
LETEWGQYWD EESRRVFFYN PLTGETAWED EAENEPEEEL EMQPGLSPGS
360 370 380 390 400
PGDPRPPTPE TDYPESLTSY PEEDYSPVGS FGEPGPTSPL TTPPGWSCHV
410 420 430 440 450
SQDKQMLYTN HFTQEQWVRL EDPHGKPYFY NPEDSSVRWE LPQVPVPAPR
460 470 480 490 500
SIHKSSQDGD TPAQASPPEE KVPAELDEVG SWEEVSPATA AVRTKTLDKA
510 520 530 540 550
GVLHRTKTAD KGKRLRKKHW SASWTVLEGG VLTFFKDSKT SAAGGLRQPS
560 570 580 590 600
KFSTPEYTVE LRGATLSWAP KDKSSRKNVL ELRSRDGSEY LIQHDSEAII
610 620 630 640 650
STWHKAIAQG IQELSAELPP EESESSRVDF GSSERLGSWQ EKEEDARPNA
660 670 680 690 700
AAPALGPVGL ESDLSKVRHK LRKFLQRRPT LQSLREKGYI KDQVFGCALA
710 720 730 740 750
ALCERERSRV PRFVQQCIRA VEARGLDIDG LYRISGNLAT IQKLRYKVDH
760 770 780 790 800
DERLDLDDGR WEDVHVITGA LKLFFRELPE PLFPFSHFRQ FIAAIKLQDQ
810 820 830 840 850
ARRSRCVRDL VRSLPAPNHD TLRMLFQHLC RVIEHGEQNR MSVQSVAIVF
860 870 880
GPTLLRPEVE ETSMPMTMVF QNQVVELILQ QCADIFPPH
Length:889
Mass (Da):98,396
Last modified:July 13, 2010 - v3
Checksum:iE341CCC4D012DA4C
GO
Isoform 2 (identifier: Q6ZUM4-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-341: Missing.

Note: No experimental confirmation available.

Show »
Length:548
Mass (Da):61,733
Checksum:i4E0EE2190C9F20E8
GO
Isoform 3 (identifier: Q6ZUM4-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     416-442: Missing.

Note: No experimental confirmation available.

Show »
Length:862
Mass (Da):95,068
Checksum:iF207CD53BDAE7EAD
GO
Isoform 4 (identifier: Q6ZUM4-4) [UniParc]FASTAAdd to Basket

Also known as: SH3D20

The sequence of this isoform differs from the canonical sequence as follows:
     221-263: DDPPEPVYAN...THTDAGTGRP → PPRALGRGGG...RRPPLSEDFG
     264-889: Missing.

Show »
Length:263
Mass (Da):28,192
Checksum:i5731E04A9F89B4D4
GO

Sequence cautioni

The sequence AAI01389.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAI01390.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAI01391.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti41 – 411S → N in AAG23796. (PubMed:15498874)Curated
Sequence conflicti162 – 1621C → R in BAF83339. (PubMed:14702039)Curated
Sequence conflicti213 – 2131P → R in AAH67345. (PubMed:15489334)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti889 – 8891H → Q.1 Publication
Corresponds to variant rs34793644 [ dbSNP | Ensembl ].
VAR_038551

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 341341Missing in isoform 2. 1 PublicationVSP_031053Add
BLAST
Alternative sequencei221 – 26343DDPPE…GTGRP → PPRALGRGGGWRARDRARTE PGRKETRSAQRRARRPPLSE DFG in isoform 4. 2 PublicationsVSP_031054Add
BLAST
Alternative sequencei264 – 889626Missing in isoform 4. 2 PublicationsVSP_031055Add
BLAST
Alternative sequencei416 – 44227Missing in isoform 3. 1 PublicationVSP_031056Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF258593 mRNA. Translation: AAG23796.1.
AK125535 mRNA. Translation: BAC86196.1.
AK290650 mRNA. Translation: BAF83339.1.
AC003070 Genomic DNA. No translation available.
AC091132 Genomic DNA. No translation available.
BC067345 mRNA. Translation: AAH67345.1.
BC101388 mRNA. Translation: AAI01389.1. Different initiation.
BC101389 mRNA. Translation: AAI01390.1. Different initiation.
BC101390 mRNA. Translation: AAI01391.1. Different initiation.
BC101391 mRNA. Translation: AAI01392.3.
CCDSiCCDS11498.1. [Q6ZUM4-2]
CCDS32670.1. [Q6ZUM4-4]
CCDS74082.1. [Q6ZUM4-1]
RefSeqiNP_001269219.1. NM_001282290.1. [Q6ZUM4-1]
NP_777579.2. NM_174919.3. [Q6ZUM4-4]
NP_954976.1. NM_199282.2. [Q6ZUM4-2]
XP_006721808.1. XM_006721745.1. [Q6ZUM4-1]
XP_006721809.1. XM_006721746.1. [Q6ZUM4-1]
XP_006725671.1. XM_006725608.1. [Q6ZUM4-1]
XP_006725672.1. XM_006725609.1. [Q6ZUM4-1]
UniGeneiHs.205326.

Genome annotation databases

EnsembliENST00000290470; ENSP00000290470; ENSG00000159314. [Q6ZUM4-4]
ENST00000376922; ENSP00000366121; ENSG00000159314. [Q6ZUM4-2]
ENST00000428638; ENSP00000403323; ENSG00000159314. [Q6ZUM4-1]
ENST00000528273; ENSP00000436137; ENSG00000159314. [Q6ZUM4-4]
ENST00000528384; ENSP00000431591; ENSG00000159314.
ENST00000610792; ENSP00000477741; ENSG00000276907. [Q6ZUM4-1]
ENST00000611188; ENSP00000481302; ENSG00000276907. [Q6ZUM4-4]
ENST00000616021; ENSP00000478738; ENSG00000276907. [Q6ZUM4-2]
GeneIDi201176.
KEGGihsa:201176.
UCSCiuc002iix.3. human. [Q6ZUM4-1]
uc010dal.3. human. [Q6ZUM4-4]

Polymorphism databases

DMDMi300669680.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF258593 mRNA. Translation: AAG23796.1 .
AK125535 mRNA. Translation: BAC86196.1 .
AK290650 mRNA. Translation: BAF83339.1 .
AC003070 Genomic DNA. No translation available.
AC091132 Genomic DNA. No translation available.
BC067345 mRNA. Translation: AAH67345.1 .
BC101388 mRNA. Translation: AAI01389.1 . Different initiation.
BC101389 mRNA. Translation: AAI01390.1 . Different initiation.
BC101390 mRNA. Translation: AAI01391.1 . Different initiation.
BC101391 mRNA. Translation: AAI01392.3 .
CCDSi CCDS11498.1. [Q6ZUM4-2 ]
CCDS32670.1. [Q6ZUM4-4 ]
CCDS74082.1. [Q6ZUM4-1 ]
RefSeqi NP_001269219.1. NM_001282290.1. [Q6ZUM4-1 ]
NP_777579.2. NM_174919.3. [Q6ZUM4-4 ]
NP_954976.1. NM_199282.2. [Q6ZUM4-2 ]
XP_006721808.1. XM_006721745.1. [Q6ZUM4-1 ]
XP_006721809.1. XM_006721746.1. [Q6ZUM4-1 ]
XP_006725671.1. XM_006725608.1. [Q6ZUM4-1 ]
XP_006725672.1. XM_006725609.1. [Q6ZUM4-1 ]
UniGenei Hs.205326.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3PP2 X-ray 1.42 A/B 491-613 [» ]
ProteinModelPortali Q6ZUM4.
SMRi Q6ZUM4. Positions 10-67, 498-612, 678-886.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 128369. 4 interactions.
IntActi Q6ZUM4. 1 interaction.
MINTi MINT-5006179.
STRINGi 9606.ENSP00000366121.

PTM databases

PhosphoSitei Q6ZUM4.

Polymorphism databases

DMDMi 300669680.

Proteomic databases

MaxQBi Q6ZUM4.
PaxDbi Q6ZUM4.
PRIDEi Q6ZUM4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000290470 ; ENSP00000290470 ; ENSG00000159314 . [Q6ZUM4-4 ]
ENST00000376922 ; ENSP00000366121 ; ENSG00000159314 . [Q6ZUM4-2 ]
ENST00000428638 ; ENSP00000403323 ; ENSG00000159314 . [Q6ZUM4-1 ]
ENST00000528273 ; ENSP00000436137 ; ENSG00000159314 . [Q6ZUM4-4 ]
ENST00000528384 ; ENSP00000431591 ; ENSG00000159314 .
ENST00000610792 ; ENSP00000477741 ; ENSG00000276907 . [Q6ZUM4-1 ]
ENST00000611188 ; ENSP00000481302 ; ENSG00000276907 . [Q6ZUM4-4 ]
ENST00000616021 ; ENSP00000478738 ; ENSG00000276907 . [Q6ZUM4-2 ]
GeneIDi 201176.
KEGGi hsa:201176.
UCSCi uc002iix.3. human. [Q6ZUM4-1 ]
uc010dal.3. human. [Q6ZUM4-4 ]

Organism-specific databases

CTDi 201176.
GeneCardsi GC17M043538.
HGNCi HGNC:31813. ARHGAP27.
HPAi HPA023919.
MIMi 610591. gene.
neXtProti NX_Q6ZUM4.
PharmGKBi PA134873327.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG279563.
GeneTreei ENSGT00760000118882.
HOVERGENi HBG005328.
InParanoidi Q6ZUM4.
OMAi TPEYTVD.
PhylomeDBi Q6ZUM4.
TreeFami TF329345.

Enzyme and pathway databases

SignaLinki Q6ZUM4.

Miscellaneous databases

GenomeRNAii 201176.
NextBioi 90073.
PROi Q6ZUM4.
SOURCEi Search...

Gene expression databases

Bgeei Q6ZUM4.
CleanExi HS_ARHGAP27.
ExpressionAtlasi Q6ZUM4. baseline and differential.
Genevestigatori Q6ZUM4.

Family and domain databases

Gene3Di 1.10.555.10. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR011047. Quinonprotein_ADH-like_supfam.
IPR015767. Rho_GTPase_act.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR001452. SH3_domain.
IPR001202. WW_dom.
[Graphical view ]
PANTHERi PTHR23181. PTHR23181. 1 hit.
Pfami PF00169. PH. 1 hit.
PF00620. RhoGAP. 1 hit.
PF00397. WW. 1 hit.
[Graphical view ]
SMARTi SM00233. PH. 1 hit.
SM00324. RhoGAP. 1 hit.
SM00326. SH3. 1 hit.
SM00456. WW. 3 hits.
[Graphical view ]
SUPFAMi SSF48350. SSF48350. 1 hit.
SSF50044. SSF50044. 1 hit.
SSF50998. SSF50998. 1 hit.
SSF51045. SSF51045. 2 hits.
PROSITEi PS50003. PH_DOMAIN. 1 hit.
PS50238. RHOGAP. 1 hit.
PS50002. SH3. 1 hit.
PS50020. WW_DOMAIN_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Large-scale cDNA transfection screening for genes related to cancer development and progression."
    Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X.
    , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J.
    Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Embryo and Prostate.
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 270-889 (ISOFORMS 1 AND 3), VARIANT GLN-889.
    Tissue: Pancreas.
  5. "Identification and characterization of ARHGAP27 gene in silico."
    Katoh Y., Katoh M.
    Int. J. Mol. Med. 14:943-947(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION, TISSUE SPECIFICITY.

Entry informationi

Entry nameiRHG27_HUMAN
AccessioniPrimary (citable) accession number: Q6ZUM4
Secondary accession number(s): A4FU35
, A8K3N5, C9JTF3, Q494U0, Q6NWZ8, Q8WY58
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 13, 2010
Last modified: November 26, 2014
This is version 106 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3