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Protein

Uncharacterized protein C3orf62

Gene

C3orf62

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-31223-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C3orf62
Gene namesi
Name:C3orf62
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:24771. C3orf62.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188315.
PharmGKBiPA143485337.

Polymorphism and mutation databases

BioMutaiC3orf62.
DMDMi74738329.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002393051 – 267Uncharacterized protein C3orf62Add BLAST267

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei210PhosphoserineBy similarity1
Modified residuei224PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6ZUJ4.
PeptideAtlasiQ6ZUJ4.
PRIDEiQ6ZUJ4.

PTM databases

PhosphoSitePlusiQ6ZUJ4.

Expressioni

Gene expression databases

BgeeiENSG00000188315.
CleanExiHS_C3orf62.
ExpressionAtlasiQ6ZUJ4. baseline and differential.
GenevisibleiQ6ZUJ4. HS.

Organism-specific databases

HPAiHPA043328.
HPA053340.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HAUS1Q96CS23EBI-2837036,EBI-2514791
ING5Q8WYH83EBI-2837036,EBI-488533
MRFAP1Q9Y6053EBI-2837036,EBI-995714
MRFAP1L1Q96HT83EBI-2837036,EBI-748896
TXNDC9O145303EBI-2837036,EBI-707554

Protein-protein interaction databases

BioGridi131974. 11 interactors.
IntActiQ6ZUJ4. 7 interactors.
STRINGi9606.ENSP00000341139.

Structurei

3D structure databases

ProteinModelPortaliQ6ZUJ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IE85. Eukaryota.
ENOG410YJB0. LUCA.
GeneTreeiENSGT00390000000252.
HOGENOMiHOG000294156.
HOVERGENiHBG081022.
InParanoidiQ6ZUJ4.
OMAiHNIVETV.
OrthoDBiEOG091G0J4A.
PhylomeDBiQ6ZUJ4.
TreeFamiTF336411.

Family and domain databases

InterProiIPR031670. DUF4712.
[Graphical view]
PfamiPF15830. DUF4712. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZUJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHYIKTWSLL GEMSEKLRRC RKELTAAIDR AFEGVSYSQE CTGQQRLELS
60 70 80 90 100
AAPLSFSLPV HRLLCRRHPL AACSSAAPFA AVPCAPENEN PAFATNHAPV
110 120 130 140 150
NAKPHALCPE RKPLTSKENV LMHSSILAPE RESWRTAGEG ENWRKENLRK
160 170 180 190 200
DMERDLKADS NMPLNNSSQE VTKDLLDMID HTSIRTIEEL AGKIEFENEL
210 220 230 240 250
NHMCGHCQDS PFKEEAWALL MDKSPQKATD ADPGSLKQAF DDHNIVETVL
260
DLEEDYNVMT SFKYQIE
Length:267
Mass (Da):30,194
Last modified:July 5, 2004 - v1
Checksum:iDE0F03026BA268F0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti71A → S in AAH61697 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_050724110E → K.Corresponds to variant rs13077498dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125642 mRNA. Translation: BAC86231.1.
BC023586 mRNA. Translation: AAH23586.1.
BC053629 mRNA. Translation: AAH53629.2.
BC061697 mRNA. Translation: AAH61697.2.
CCDSiCCDS2792.1.
RefSeqiNP_940964.1. NM_198562.2.
UniGeneiHs.403828.

Genome annotation databases

EnsembliENST00000343010; ENSP00000341139; ENSG00000188315.
GeneIDi375341.
KEGGihsa:375341.
UCSCiuc003cwn.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125642 mRNA. Translation: BAC86231.1.
BC023586 mRNA. Translation: AAH23586.1.
BC053629 mRNA. Translation: AAH53629.2.
BC061697 mRNA. Translation: AAH61697.2.
CCDSiCCDS2792.1.
RefSeqiNP_940964.1. NM_198562.2.
UniGeneiHs.403828.

3D structure databases

ProteinModelPortaliQ6ZUJ4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi131974. 11 interactors.
IntActiQ6ZUJ4. 7 interactors.
STRINGi9606.ENSP00000341139.

PTM databases

PhosphoSitePlusiQ6ZUJ4.

Polymorphism and mutation databases

BioMutaiC3orf62.
DMDMi74738329.

Proteomic databases

PaxDbiQ6ZUJ4.
PeptideAtlasiQ6ZUJ4.
PRIDEiQ6ZUJ4.

Protocols and materials databases

DNASUi375341.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000343010; ENSP00000341139; ENSG00000188315.
GeneIDi375341.
KEGGihsa:375341.
UCSCiuc003cwn.3. human.

Organism-specific databases

CTDi375341.
GeneCardsiC3orf62.
HGNCiHGNC:24771. C3orf62.
HPAiHPA043328.
HPA053340.
neXtProtiNX_Q6ZUJ4.
OpenTargetsiENSG00000188315.
PharmGKBiPA143485337.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IE85. Eukaryota.
ENOG410YJB0. LUCA.
GeneTreeiENSGT00390000000252.
HOGENOMiHOG000294156.
HOVERGENiHBG081022.
InParanoidiQ6ZUJ4.
OMAiHNIVETV.
OrthoDBiEOG091G0J4A.
PhylomeDBiQ6ZUJ4.
TreeFamiTF336411.

Enzyme and pathway databases

BioCyciZFISH:G66-31223-MONOMER.

Miscellaneous databases

ChiTaRSiC3orf62. human.
GenomeRNAii375341.
PROiQ6ZUJ4.

Gene expression databases

BgeeiENSG00000188315.
CleanExiHS_C3orf62.
ExpressionAtlasiQ6ZUJ4. baseline and differential.
GenevisibleiQ6ZUJ4. HS.

Family and domain databases

InterProiIPR031670. DUF4712.
[Graphical view]
PfamiPF15830. DUF4712. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCC062_HUMAN
AccessioniPrimary (citable) accession number: Q6ZUJ4
Secondary accession number(s): Q6P7E9, Q7Z3X6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.