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Protein

Myb/SANT-like DNA-binding domain-containing protein 1

Gene

MSANTD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Myb/SANT-like DNA-binding domain-containing protein 1
Gene namesi
Name:MSANTD1
Synonyms:C4orf44
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:33741. MSANTD1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162379942.

Polymorphism and mutation databases

BioMutaiMSANTD1.
DMDMi284018071.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 278278Myb/SANT-like DNA-binding domain-containing protein 1PRO_0000321819Add
BLAST

Proteomic databases

PaxDbiQ6ZTZ1.
PRIDEiQ6ZTZ1.

PTM databases

iPTMnetiQ6ZTZ1.
PhosphoSiteiQ6ZTZ1.

Expressioni

Gene expression databases

BgeeiQ6ZTZ1.
CleanExiHS_C4orf44.
ExpressionAtlasiQ6ZTZ1. baseline and differential.
GenevisibleiQ6ZTZ1. HS.

Organism-specific databases

HPAiHPA055038.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000411584.

Structurei

3D structure databases

ProteinModelPortaliQ6ZTZ1.
SMRiQ6ZTZ1. Positions 40-127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini44 – 12986Myb-likeAdd
BLAST

Sequence similaritiesi

Contains 1 Myb-like domain.Curated

Phylogenomic databases

eggNOGiKOG4282. Eukaryota.
ENOG410YYXY. LUCA.
GeneTreeiENSGT00390000002245.
HOGENOMiHOG000111471.
HOVERGENiHBG065074.
InParanoidiQ6ZTZ1.
PhylomeDBiQ6ZTZ1.
TreeFamiTF331923.

Family and domain databases

InterProiIPR026095. Myb/SANT-like_DNA-bd_dom_prot.
[Graphical view]
PANTHERiPTHR22666. PTHR22666. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6ZTZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRGAGPGPS LSALSHPTGA SGMAAAEGPG YLVSPQAEKH RRARNWTDAE
60 70 80 90 100
MRGLMLVWEE FFDELKQTKR NAKVYEKMAS KLFEMTGERR LGEEIKIKIT
110 120 130 140 150
NMTFQYRKLK CMTDSESAPP DWPYYLAIDG ILAKVPESCD GKLPDSQPPG
160 170 180 190 200
PSTSQTEASL SPPAKSTPLY FPYNQCSYEG RFEDDRSDSS SSLLSLKFRS
210 220 230 240 250
EERPVKKRKV QSCHLQKKQL RLLEAMVEEQ RRLSRAVEET CREVRRVLDQ
260 270
QHILQVQSLQ LQERMMSLLE RIITKSSV
Length:278
Mass (Da):31,632
Last modified:January 19, 2010 - v2
Checksum:i9A522BBEFF0ADB6E
GO

Sequence cautioni

The sequence BAC86436.1 differs from that shown.Probable cloning artifact.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti64 – 641E → G in BAC86436 (PubMed:14702039).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL390059 Genomic DNA. No translation available.
AK126094 mRNA. Translation: BAC86436.1. Sequence problems.
CCDSiCCDS47003.1.
RefSeqiNP_001036155.1. NM_001042690.1.
UniGeneiHs.442291.

Genome annotation databases

EnsembliENST00000438480; ENSP00000411584; ENSG00000188981.
GeneIDi345222.
KEGGihsa:345222.
UCSCiuc003ggs.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL390059 Genomic DNA. No translation available.
AK126094 mRNA. Translation: BAC86436.1. Sequence problems.
CCDSiCCDS47003.1.
RefSeqiNP_001036155.1. NM_001042690.1.
UniGeneiHs.442291.

3D structure databases

ProteinModelPortaliQ6ZTZ1.
SMRiQ6ZTZ1. Positions 40-127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000411584.

PTM databases

iPTMnetiQ6ZTZ1.
PhosphoSiteiQ6ZTZ1.

Polymorphism and mutation databases

BioMutaiMSANTD1.
DMDMi284018071.

Proteomic databases

PaxDbiQ6ZTZ1.
PRIDEiQ6ZTZ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000438480; ENSP00000411584; ENSG00000188981.
GeneIDi345222.
KEGGihsa:345222.
UCSCiuc003ggs.4. human.

Organism-specific databases

CTDi345222.
GeneCardsiMSANTD1.
HGNCiHGNC:33741. MSANTD1.
HPAiHPA055038.
neXtProtiNX_Q6ZTZ1.
PharmGKBiPA162379942.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4282. Eukaryota.
ENOG410YYXY. LUCA.
GeneTreeiENSGT00390000002245.
HOGENOMiHOG000111471.
HOVERGENiHBG065074.
InParanoidiQ6ZTZ1.
PhylomeDBiQ6ZTZ1.
TreeFamiTF331923.

Miscellaneous databases

GenomeRNAii345222.
NextBioi98834.
PROiQ6ZTZ1.

Gene expression databases

BgeeiQ6ZTZ1.
CleanExiHS_C4orf44.
ExpressionAtlasiQ6ZTZ1. baseline and differential.
GenevisibleiQ6ZTZ1. HS.

Family and domain databases

InterProiIPR026095. Myb/SANT-like_DNA-bd_dom_prot.
[Graphical view]
PANTHERiPTHR22666. PTHR22666. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-243.
    Tissue: Testis.

Entry informationi

Entry nameiMSD1_HUMAN
AccessioniPrimary (citable) accession number: Q6ZTZ1
Secondary accession number(s): C9J6V0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 19, 2010
Last modified: March 16, 2016
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.