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Protein

Protein FAM92B

Gene

FAM92B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM92B
Gene namesi
Name:FAM92B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:24781. FAM92B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142671826.

Polymorphism and mutation databases

BioMutaiFAM92B.
DMDMi74738328.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304Protein FAM92BPRO_0000333004Add
BLAST

Proteomic databases

MaxQBiQ6ZTR7.
PaxDbiQ6ZTR7.
PeptideAtlasiQ6ZTR7.
PRIDEiQ6ZTR7.

PTM databases

iPTMnetiQ6ZTR7.
PhosphoSiteiQ6ZTR7.

Expressioni

Gene expression databases

BgeeiENSG00000153789.
CleanExiHS_FAM92B.
ExpressionAtlasiQ6ZTR7. baseline and differential.

Organism-specific databases

HPAiHPA041022.

Interactioni

Protein-protein interaction databases

IntActiQ6ZTR7. 1 interaction.
STRINGi9606.ENSP00000443411.

Structurei

3D structure databases

ProteinModelPortaliQ6ZTR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM92 family.Curated

Phylogenomic databases

eggNOGiENOG410IFRR. Eukaryota.
ENOG410YE7H. LUCA.
GeneTreeiENSGT00390000010285.
HOGENOMiHOG000060253.
HOVERGENiHBG107895.
InParanoidiQ6ZTR7.
OMAiRTTHQLE.
PhylomeDBiQ6ZTR7.
TreeFamiTF324316.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR009602. FAM92.
[Graphical view]
PANTHERiPTHR21223. PTHR21223. 1 hit.
PfamiPF06730. FAM92. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZTR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIVFSRDSQ VRVMENTVAN TEKYFGQFCS LLAAYTRKTA RLRDKADQLV
60 70 80 90 100
KQLIDFANSE NPELRATMRG FAEDLAKVQD YRQAQVERLE TKVVNPLKLY
110 120 130 140 150
GAQIKQTRAE IKKFKHVQNH EIKQLEKLEK LRQKSPSDQQ MISQAETRVQ
160 170 180 190 200
RAAVDSSRTT LQLEETVDGF QRQKLKDLQK FFCDFVTIEM VFHAKAVEVY
210 220 230 240 250
SSAFQTLEKY DLERDLLDFR AKMQGVYGHY DTRLLANTSP PPSVLQSLAS
260 270 280 290 300
QGTLQVQLSR ANEDPEHPHA NHGRFSLCEW VVKGQPAHCV CGQGGHLMLP

GHSL
Length:304
Mass (Da):34,785
Last modified:July 5, 2004 - v1
Checksum:i906F945DECF6928A
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti22 – 221E → K.
Corresponds to variant rs9934891 [ dbSNP | Ensembl ].
VAR_043035

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126284 mRNA. Translation: BAC86515.1.
BC093665 mRNA. Translation: AAH93665.1.
BC111944 mRNA. Translation: AAI11945.1.
CCDSiCCDS32500.1.
RefSeqiNP_940893.1. NM_198491.2.
XP_011521365.1. XM_011523063.1.
UniGeneiHs.125713.

Genome annotation databases

EnsembliENST00000539556; ENSP00000443411; ENSG00000153789.
GeneIDi339145.
KEGGihsa:339145.
UCSCiuc059xyr.1. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126284 mRNA. Translation: BAC86515.1.
BC093665 mRNA. Translation: AAH93665.1.
BC111944 mRNA. Translation: AAI11945.1.
CCDSiCCDS32500.1.
RefSeqiNP_940893.1. NM_198491.2.
XP_011521365.1. XM_011523063.1.
UniGeneiHs.125713.

3D structure databases

ProteinModelPortaliQ6ZTR7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6ZTR7. 1 interaction.
STRINGi9606.ENSP00000443411.

PTM databases

iPTMnetiQ6ZTR7.
PhosphoSiteiQ6ZTR7.

Polymorphism and mutation databases

BioMutaiFAM92B.
DMDMi74738328.

Proteomic databases

MaxQBiQ6ZTR7.
PaxDbiQ6ZTR7.
PeptideAtlasiQ6ZTR7.
PRIDEiQ6ZTR7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000539556; ENSP00000443411; ENSG00000153789.
GeneIDi339145.
KEGGihsa:339145.
UCSCiuc059xyr.1. human.

Organism-specific databases

CTDi339145.
GeneCardsiFAM92B.
HGNCiHGNC:24781. FAM92B.
HPAiHPA041022.
neXtProtiNX_Q6ZTR7.
PharmGKBiPA142671826.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFRR. Eukaryota.
ENOG410YE7H. LUCA.
GeneTreeiENSGT00390000010285.
HOGENOMiHOG000060253.
HOVERGENiHBG107895.
InParanoidiQ6ZTR7.
OMAiRTTHQLE.
PhylomeDBiQ6ZTR7.
TreeFamiTF324316.

Miscellaneous databases

GenomeRNAii339145.
PROiQ6ZTR7.

Gene expression databases

BgeeiENSG00000153789.
CleanExiHS_FAM92B.
ExpressionAtlasiQ6ZTR7. baseline and differential.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR009602. FAM92.
[Graphical view]
PANTHERiPTHR21223. PTHR21223. 1 hit.
PfamiPF06730. FAM92. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFA92B_HUMAN
AccessioniPrimary (citable) accession number: Q6ZTR7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.