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Protein

Lipocalin-like 1 protein

Gene

LCNL1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-32341-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipocalin-like 1 protein
Gene namesi
Name:LCNL1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:34436. LCNL1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000214402.
PharmGKBiPA164722092.

Polymorphism and mutation databases

BioMutaiLCNL1.
DMDMi296434562.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003484701 – 164Lipocalin-like 1 proteinAdd BLAST164

Proteomic databases

PaxDbiQ6ZST4.
PRIDEiQ6ZST4.

Expressioni

Gene expression databases

BgeeiENSG00000214402.
GenevisibleiQ6ZST4. HS.

Organism-specific databases

HPAiHPA060268.

Structurei

3D structure databases

ProteinModelPortaliQ6ZST4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the calycin superfamily. Lipocalin family.Curated

Phylogenomic databases

eggNOGiENOG410IXK6. Eukaryota.
ENOG411141C. LUCA.
GeneTreeiENSGT00620000088005.
HOGENOMiHOG000208505.
InParanoidiQ6ZST4.
OMAiVAFSDYQ.
OrthoDBiEOG091G0NUE.
PhylomeDBiQ6ZST4.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6ZST4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGVVSDDQD FLDSKDTMKM AVVLVTPLGN GDLALKFGYP TPHGGCQKMD
60 70 80 90 100
TTFTEGAVPG QFSNPAMALS DIRVAFSDYQ HFALLYLEMR KGGLRNQWLQ
110 120 130 140 150
LYGGRAAGRR PRHPRFGSGM SPLCLHQPFL HAEGGTAGSW CLWPRVPAPP
160
CPSLPLFAPP APSL
Length:164
Mass (Da):17,784
Last modified:May 18, 2010 - v2
Checksum:iE0C265A527C6A0BB
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_04618968A → T.1 PublicationCorresponds to variant rs17578859dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127160 mRNA. Translation: BAC86862.1.
AL807752 Genomic DNA. No translation available.
CCDSiCCDS43908.1.
RefSeqiNP_997393.3. NM_207510.3.
UniGeneiHs.695210.

Genome annotation databases

EnsembliENST00000408973; ENSP00000386162; ENSG00000214402.
GeneIDi401562.
KEGGihsa:401562.
UCSCiuc004ckh.2. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127160 mRNA. Translation: BAC86862.1.
AL807752 Genomic DNA. No translation available.
CCDSiCCDS43908.1.
RefSeqiNP_997393.3. NM_207510.3.
UniGeneiHs.695210.

3D structure databases

ProteinModelPortaliQ6ZST4.
ModBaseiSearch...
MobiDBiSearch...

Polymorphism and mutation databases

BioMutaiLCNL1.
DMDMi296434562.

Proteomic databases

PaxDbiQ6ZST4.
PRIDEiQ6ZST4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000408973; ENSP00000386162; ENSG00000214402.
GeneIDi401562.
KEGGihsa:401562.
UCSCiuc004ckh.2. human.

Organism-specific databases

CTDi401562.
GeneCardsiLCNL1.
HGNCiHGNC:34436. LCNL1.
HPAiHPA060268.
neXtProtiNX_Q6ZST4.
OpenTargetsiENSG00000214402.
PharmGKBiPA164722092.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IXK6. Eukaryota.
ENOG411141C. LUCA.
GeneTreeiENSGT00620000088005.
HOGENOMiHOG000208505.
InParanoidiQ6ZST4.
OMAiVAFSDYQ.
OrthoDBiEOG091G0NUE.
PhylomeDBiQ6ZST4.

Enzyme and pathway databases

BioCyciZFISH:G66-32341-MONOMER.

Miscellaneous databases

GenomeRNAii401562.
PROiQ6ZST4.

Gene expression databases

BgeeiENSG00000214402.
GenevisibleiQ6ZST4. HS.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
SUPFAMiSSF50814. SSF50814. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLCNL1_HUMAN
AccessioniPrimary (citable) accession number: Q6ZST4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: May 18, 2010
Last modified: November 2, 2016
This is version 95 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.