SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6ZSJ8

- CA122_HUMAN

UniProt

Q6ZSJ8 - CA122_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Uncharacterized protein C1orf122
Gene
C1orf122
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C1orf122
Alternative name(s):
Protein ALAESM
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:24789. C1orf122.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142672440.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 110110Uncharacterized protein C1orf122
PRO_0000254193Add
BLAST

Proteomic databases

MaxQBiQ6ZSJ8.
PaxDbiQ6ZSJ8.
PRIDEiQ6ZSJ8.

PTM databases

PhosphoSiteiQ6ZSJ8.

Expressioni

Gene expression databases

ArrayExpressiQ6ZSJ8.
BgeeiQ6ZSJ8.
CleanExiHS_C1orf122.
GenevestigatoriQ6ZSJ8.

Interactioni

Protein-protein interaction databases

BioGridi126077. 1 interaction.
IntActiQ6ZSJ8. 1 interaction.
STRINGi9606.ENSP00000362133.

Structurei

3D structure databases

ProteinModelPortaliQ6ZSJ8.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili36 – 6833 Reviewed prediction
Add
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG258495.
HOGENOMiHOG000111246.
OrthoDBiEOG7GBG0F.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6ZSJ8-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MEWGPGSDWS RGEAAGVDRG KAGLGLGGRP PPQPPREERA QQLLDAVEQR    50
QRQLLDTIAA CEEMLRQLGR RRPEPAGGGN VSAKPGAPPQ PAVSARGGFP 100
KDAGDGAAEP 110
Length:110
Mass (Da):11,471
Last modified:September 22, 2009 - v2
Checksum:iC63352FB57850CFE
GO
Isoform 2 (identifier: Q6ZSJ8-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-63: Missing.

Note: No experimental confirmation available.

Show »
Length:47
Mass (Da):4,650
Checksum:iB2CDF8E8200DCF93
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 6363Missing in isoform 2.
VSP_046648Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK127381 mRNA. Translation: BAC86950.1. Sequence problems.
AY517499 mRNA. Translation: AAS76640.1.
AL929472 Genomic DNA. Translation: CAH70085.1. Sequence problems.
BC057819 mRNA. Translation: AAH57819.1. Sequence problems.
CCDSiCCDS427.2. [Q6ZSJ8-1]
CCDS44112.1. [Q6ZSJ8-2]
RefSeqiNP_001136198.1. NM_001142726.1. [Q6ZSJ8-2]
NP_940848.2. NM_198446.2. [Q6ZSJ8-1]
UniGeneiHs.532749.

Genome annotation databases

EnsembliENST00000373042; ENSP00000362133; ENSG00000197982. [Q6ZSJ8-1]
ENST00000373043; ENSP00000362134; ENSG00000197982. [Q6ZSJ8-2]
ENST00000468084; ENSP00000434520; ENSG00000197982. [Q6ZSJ8-2]
GeneIDi127687.
KEGGihsa:127687.
UCSCiuc001ccd.2. human. [Q6ZSJ8-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK127381 mRNA. Translation: BAC86950.1 . Sequence problems.
AY517499 mRNA. Translation: AAS76640.1 .
AL929472 Genomic DNA. Translation: CAH70085.1 . Sequence problems.
BC057819 mRNA. Translation: AAH57819.1 . Sequence problems.
CCDSi CCDS427.2. [Q6ZSJ8-1 ]
CCDS44112.1. [Q6ZSJ8-2 ]
RefSeqi NP_001136198.1. NM_001142726.1. [Q6ZSJ8-2 ]
NP_940848.2. NM_198446.2. [Q6ZSJ8-1 ]
UniGenei Hs.532749.

3D structure databases

ProteinModelPortali Q6ZSJ8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 126077. 1 interaction.
IntActi Q6ZSJ8. 1 interaction.
STRINGi 9606.ENSP00000362133.

PTM databases

PhosphoSitei Q6ZSJ8.

Proteomic databases

MaxQBi Q6ZSJ8.
PaxDbi Q6ZSJ8.
PRIDEi Q6ZSJ8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000373042 ; ENSP00000362133 ; ENSG00000197982 . [Q6ZSJ8-1 ]
ENST00000373043 ; ENSP00000362134 ; ENSG00000197982 . [Q6ZSJ8-2 ]
ENST00000468084 ; ENSP00000434520 ; ENSG00000197982 . [Q6ZSJ8-2 ]
GeneIDi 127687.
KEGGi hsa:127687.
UCSCi uc001ccd.2. human. [Q6ZSJ8-1 ]

Organism-specific databases

CTDi 127687.
GeneCardsi GC01P038272.
HGNCi HGNC:24789. C1orf122.
neXtProti NX_Q6ZSJ8.
PharmGKBi PA142672440.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG258495.
HOGENOMi HOG000111246.
OrthoDBi EOG7GBG0F.

Miscellaneous databases

ChiTaRSi C1orf122. human.
GenomeRNAii 127687.
NextBioi 82162.

Gene expression databases

ArrayExpressi Q6ZSJ8.
Bgeei Q6ZSJ8.
CleanExi HS_C1orf122.
Genevestigatori Q6ZSJ8.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Subthalamic nucleus.
  2. Chen S., Guo J.H., Yu L.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  3. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.

Entry informationi

Entry nameiCA122_HUMAN
AccessioniPrimary (citable) accession number: Q6ZSJ8
Secondary accession number(s): A2RQF4, E9PQ13, Q56A71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: September 22, 2009
Last modified: July 9, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi