Q6ZSG2 (F196A_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein FAM196A

Gene names

Name:	FAM196A
Synonyms:	C10orf141

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	479 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the FAM196 family.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 479	479	Protein FAM196A		PRO_0000329446
Regions
	Coiled coil	353 – 379	27	Potential
Natural variations
	Natural variant	147	1	A → V. Corresponds to variant rs11594560 [ dbSNP | Ensembl ].		VAR_042679

Sequences

	Sequence		Length	Mass (Da)
	Q6ZSG2 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 839D6E8DB895F308	FASTA	479	52,909
	10 20 30 40 50 60 MVSKDTGKCI LTTSESEVEP AACLALEMKY ALDPNRQIKK RNKALQVRFK DICEAQNEQR 70 80 90 100 110 120 DTQLSSGQLG EKREAKPVSC RAAYRKYMTV PARRSIPNVT KSTGVQTSPD LKKCYQTFPL 130 140 150 160 170 180 DRKKGNLKSL PAADPFKSQN NGFLTDAKEK NEAGPMEEAR PCGAGRVHKT TALVFHSNQH 190 200 210 220 230 240 MNTVDQPLGV NCTEPCKSPE PLSYGEAALQ NSTRPPSEEP DYQLLGRAKQ DRGRPNSEEP 250 260 270 280 290 300 APPALRRVFK TEVATVYAPA LSARAPEPGL SDSAAASQWS LCPADDERRR ATHLNGLQAP 310 320 330 340 350 360 SETALACSPP MQCLSPECSE QPSQTHTPPG LGNQPSPTAV AAGEECQRIV PHTEVVDLKA 370 380 390 400 410 420 QLQMMENLIS SSQETIKVLL GVIQELEKGE AHREGLSYRT GQDTANCDTC RNSACIIYSV 430 440 450 460 470 ELDFKQQEDK LQPVLRKLHP IEETQVIPSP YSQETYSSTP KQKSKTESKK HGRWKLWFL

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Thalamus.

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK127465 mRNA. Translation: BAC86991.1. BC131825 mRNA. Translation: AAI31826.1. BC137112 mRNA. Translation: AAI37113.1.
IPI	IPI00412891.
RefSeq	NP_001034851.1. NM_001039762.2.
UniGene	Hs.613882.
3D structure databases
ProteinModelPortal	Q6ZSG2.
ModBase	Search...
PTM databases
PhosphoSite	Q6ZSG2.
Polymorphism databases
DMDM	74711413.
Proteomic databases
PRIDE	Q6ZSG2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	642938.
KEGG	hsa:642938.
UCSC	uc001lju.1. human.
Organism-specific databases
CTD	642938.
GeneCards	GC10M128934.
HGNC	HGNC:33859. FAM196A.
HPA	HPA035898. HPA035899.
neXtProt	NX_Q6ZSG2.
PharmGKB	PA162377658. PA165548646.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG19146.
GeneTree	ENSGT00530000063787.
HOVERGEN	HBG064694.
InParanoid	Q6ZSG2.
PhylomeDB	Q6ZSG2.
Gene expression databases
Bgee	Q6ZSG2.
CleanEx	HS_C10orf141.
Genevestigator	Q6ZSG2.
Family and domain databases
ProtoNet	Search...
Other
NextBio	114319.

Entry information

Entry name

F196A_HUMAN

Accession

Primary (citable) accession number: Q6ZSG2
Secondary accession number(s): B2RNT4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.