Q6ZS81 (WDFY4_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
WD repeat- and FYVE domain-containing protein 4

Gene names

Name:	WDFY4
Synonyms:	C10orf64, KIAA1607

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	3184 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Contains 1 BEACH domain. Contains 5 WD repeats.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat Transmembrane Transmembrane helix WD repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q6ZS81-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q6ZS81-2)

The sequence of this isoform differs from the canonical sequence as follows:
     627-654: SLLRILVTPKGRAAFRVSSGFNGLLSLL → VISSPPLRLASLWICTKRSTFAQAFVFM
     655-3184: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q6ZS81-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1007-1042: SPRNLQPQRAALAPSFVEFDMSVEGYGCLFIPTLST → FPACWKPNIWKDNLAQKPVAGDAAQCNIFPPASSVL
     1043-3184: Missing.

Isoform 4 (identifier: Q6ZS81-4)

The sequence of this isoform differs from the canonical sequence as follows:
     3111-3184: RPAGEEPPAQ...GRIFCWSADG → LQMGRKREAA...QPSPWPMGLL

Note: No experimental confirmation available.

Isoform 5 (identifier: Q6ZS81-5)

The sequence of this isoform differs from the canonical sequence as follows:
     2862-2920: DMYLFSLGSE...DFSCCLGSYG → GDSLAMHCLV...SRGVSSLGSV
     2921-3184: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 3184	3184	WD repeat- and FYVE domain-containing protein 4		PRO_0000251254
Regions
	Transmembrane	1627 – 1647	21	Helical; Potential
	Transmembrane	2048 – 2068	21	Helical; Potential
	Domain	2527 – 2821	295	BEACH
	Repeat	2930 – 2970	41	WD 1
	Repeat	2980 – 3019	40	WD 2
	Repeat	3022 – 3061	40	WD 3
	Repeat	3071 – 3109	39	WD 4
	Repeat	3151 – 3184	34	WD 5
Natural variations
	Alternative sequence	627 – 654	28	SLLRI…LLSLL → VISSPPLRLASLWICTKRST FAQAFVFM in isoform 2.		VSP_020750
	Alternative sequence	655 – 3184	2530	Missing in isoform 2.		VSP_020751
	Alternative sequence	1007 – 1042	36	SPRNL…PTLST → FPACWKPNIWKDNLAQKPVA GDAAQCNIFPPASSVL in isoform 3.		VSP_035683
	Alternative sequence	1043 – 3184	2142	Missing in isoform 3.		VSP_035684
	Alternative sequence	2862 – 2920	59	DMYLF…LGSYG → GDSLAMHCLVSCPRVVPSVA GFLWRSSTTYLGKVLGTDFE WLHLQSQPDSRGVSSLGSV in isoform 5.		VSP_035685
	Alternative sequence	2921 – 3184	264	Missing in isoform 5.		VSP_035686
	Alternative sequence	3111 – 3184	74	RPAGE…WSADG → LQMGRKREAAEALAQQCQAE GGRGDWGLSSAYRRNPQGLL PHSSQGRASGNHSSAAQPSP WPMGLL in isoform 4.		VSP_035687
	Natural variant	214	1	S → P. Ref.1 Corresponds to variant rs7072606 [ dbSNP | Ensembl ].		VAR_027684
	Natural variant	944	1	S → F. Corresponds to variant rs12242384 [ dbSNP | Ensembl ].		VAR_027685
	Natural variant	2527	1	S → N. Ref.3 Ref.4 Ref.5 Corresponds to variant rs2663046 [ dbSNP | Ensembl ].		VAR_047261
Experimental info
	Sequence conflict	1337	1	A → G in BAB84911. Ref.4
	Sequence conflict	2595	1	D → G in AAH47574. Ref.3
	Sequence conflict	2683	1	E → K in AAH47574. Ref.3
	Sequence conflict	3118	1	P → L in AAH47574. Ref.3
	Sequence conflict	3118	1	P → L in BAB13433. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 25, 2008. Version 3. Checksum: 6743F924EE534E44	FASTA	3,184	353,610
	10 20 30 40 50 60 MEAEDLSKAE DRNEDPGSKN EGQLAAVQPD VPHGGQSSSP TALWDMLERK FLEYQQLTHK 70 80 90 100 110 120 SPIERQKSLL SLLPLFLKAW EHSVGIICFP SLQRLAEDVS DQLAQQLQKA LVGKPAEQAR 130 140 150 160 170 180 LAAGQLLWWK GDVDQDGYLL LKSVYVLTGT DSETLGRVAE SGLPALLLQC LYLFFVFPLD 190 200 210 220 230 240 KDELLESDLQ VQKMFVQMLL NICSDSQGLE GLLSGSELQS LLIATTCLRE HSCCFWKEPT 250 260 270 280 290 300 FCVLRAISKA QNLSIIQYLQ ATDCVRLSLQ NLSRLTDTLP APEVSEAVSL ILGFVKDSYP 310 320 330 340 350 360 VSSALFLEFE NSEGYPLLLK VLLRYDGLTQ SEVDPHLEEL LGLVVWLTTC GRSELKVFDS 370 380 390 400 410 420 ITYPQLEGFK FHHEASGVTV KNLQAFQVLQ NVFHKASDSV LCIQVLSVIR TMWAWNARNF 430 440 450 460 470 480 FLLEWTLQPI SQFVEIMPLK PAPVQEHFFQ LLEALVFELH YVPHEILRKV QHLIKESPGP 490 500 510 520 530 540 SCTLMALQSI LSIAGGDPLF TDIFRDSGLL GLLLAQLRKQ AKIMRKSGNK VSTPGVQDPE 550 560 570 580 590 600 RELTCVMLRI VVTLLKGSVR NAVVLKDHGM VPFIKIFLDD ECYREASLSI LEQLSAINAE 610 620 630 640 650 660 EYMSIIVGAL CSSTQGELQL KLDLLKSLLR ILVTPKGRAA FRVSSGFNGL LSLLSDLEGS 670 680 690 700 710 720 LQEPPLQAWG AVSPRQTLEL VLYTLCAVSA ALHWDPVNGY FFRRNGLFEK LAEDLCLLGC 730 740 750 760 770 780 FGALEEEGNL LRSWVDTKAR PFADLLGTAF SSSGSLPPRI QSCLQILGFL DSMASGTLHL 790 800 810 820 830 840 RGDLKESLRT KQGPVVDVQK GETGSDPQRN FKQWPDLEER MDEGDAAIMH PGVVCIMVRL 850 860 870 880 890 900 LPRLYHEDHP QLSEEIQCSL ASHIQSLVKS EKNRQVMCEA GLLGTLMASC HRALVTSGSP 910 920 930 940 950 960 LHSRLIRIFE KLASQAIEPD VLRQFLGLGI PSSLSATTKI LDSSHTHRGN PGCSGSQTAQ 970 980 990 1000 1010 1020 GLAEGPWPAA PDAGLHPGVT QAPQPLGESQ DSTTALQTAL SLISMTSPRN LQPQRAALAP 1030 1040 1050 1060 1070 1080 SFVEFDMSVE GYGCLFIPTL STVMGTSTEY SVSGGIGTGA TRPFPPPGGL TFSCWFLISR 1090 1100 1110 1120 1130 1140 HGAATEGHPL RFLTLVRHLA RTEQPFVCFS VSLCPDDLSL VVSTEEKEFQ PLDVMEPEDD 1150 1160 1170 1180 1190 1200 SEPSAGCQLQ VRCGQLLACG QWHHLAVVVT KEMKRHCTVS TCLDGQVIGS AKMLYIQALP 1210 1220 1230 1240 1250 1260 GPFLSMDPSA FVDVYGYIAT PRVWKQKSSL IWRLGPTYLF EEAISMETLE VINKLGPRYC 1270 1280 1290 1300 1310 1320 GNFQAVHVQG EDLDSEATPF VAEERVSFGL HIASSSITSV ADIRNAYNEV DSRLIAKEMN 1330 1340 1350 1360 1370 1380 ISSRDNAMPV FLLRNCAGHL SGSLRTIGAV AVGQLGVRVF HSSPAASSLD FIGGPAILLG 1390 1400 1410 1420 1430 1440 LISLATDDHT MYAAVKVLHS VLTSNAMCDF LMQHICGYQI MAFLLRKKAS LLNHRIFQLI 1450 1460 1470 1480 1490 1500 LSVAGTVELG FRSSAITNTG VFQHILCNFE LWMNTADNLE LSLFSHLLEI LQSPREGPRN 1510 1520 1530 1540 1550 1560 AEAAHQAQLI PKLIFLFNEP SLIPSKISTI IGILACQLRG HFSTQDLLRI GLFVVYTLKP 1570 1580 1590 1600 1610 1620 SSVNERQICM DGALDPSLPA GSQTSGKTIW LRNQLLEMLL SVISSPQLHL SSESKEEMFL 1630 1640 1650 1660 1670 1680 KLGPDWFLLL LQGHLHASTT VLALKLLLYF LASPSLRTRF RDGLCAGSWV ERSTEGVDIV 1690 1700 1710 1720 1730 1740 MDNLKSQSPL PEQSPCLLPG FRVLNDFLAH HVHIPEVYLI VSTFFLQTPL TELMDGPKDS 1750 1760 1770 1780 1790 1800 LDAMLQWLLQ RHHQEEVLQA GLCTEGALLL LEMLKATMSQ PLAGSEDGAW AQTFPASVLQ 1810 1820 1830 1840 1850 1860 FLSLVHRTYP QDPAWRAPEF LQTLAIAAFP LGAQKGVGAE STRNTSSPEA AAEGDSTVEG 1870 1880 1890 1900 1910 1920 LQAPTKAHPA RRKLREFTQL LLRELLLGAS SPKQWLPLEV LLEASPDHAT SQQKRDFQSE 1930 1940 1950 1960 1970 1980 VLLSAMELFH MTSGGDAAMF RDGKEPQPSA EAAAAPSLAN ISCFTQKLVE KLYSGMFSAD 1990 2000 2010 2020 2030 2040 PRHILLFILE HIMVVIETAS SQRDTVLSTL YSSLNKVILY CLSKPQQSLS ECLGLLSILG 2050 2060 2070 2080 2090 2100 FLQEHWDVVF ATYNSNISFL LCLMHCLLLL NERSYPEGFG LEPKPRMSTY HQVFLSPNED 2110 2120 2130 2140 2150 2160 VKEKREDLPS LSDVQHNIQK TVQTLWQQLV AQRQQTLEDA FKIDLSVKPG EREVKIEEVT 2170 2180 2190 2200 2210 2220 PLWEETMLKA WQHYLASEKK SLASRSNVAH HSKVTLWSGS LSSAMKLMPG RQAKDPECKT 2230 2240 2250 2260 2270 2280 EDFVSCIENY RRRGQELYAS LYKDHVQRRK CGNIKAANAW ARIQEQLFGE LGLWSQGEET 2290 2300 2310 2320 2330 2340 KPCSPWELDW REGPARMRKR IKRLSPLEAL SSGRHKESQD KNDHISQTNA ENQDELTLRE 2350 2360 2370 2380 2390 2400 AEGEPDEVGV DCTQLTFFPA LHESLHSEDF LELCRERQVI LQELLDKEKV TQKFSLVIVQ 2410 2420 2430 2440 2450 2460 GHLVSEGVLL FGHQHFYICE NFTLSPTGDV YCTRHCLSNI SDPFIFNLCS KDRSTDHYSC 2470 2480 2490 2500 2510 2520 QCHSYADMRE LRQARFLLQD IALEIFFHNG YSKFLVFYNN DRSKAFKSFC SFQPSLKGKA 2530 2540 2550 2560 2570 2580 TSEDTLSLRR YPGSDRIMLQ KWQKRDISNF EYLMYLNTAA GRTCNDYMQY PVFPWVLADY 2590 2600 2610 2620 2630 2640 TSETLNLANP KIFRDLSKPM GAQTKERKLK FIQRFKEVEK TEGDMTVQCH YYTHYSSAII 2650 2660 2670 2680 2690 2700 VASYLVRMPP FTQAFCALQG GSFDVADRMF HSVKSTWESA SRENMSDVRE LTPEFFYLPE 2710 2720 2730 2740 2750 2760 FLTNCNGVEF GCMQDGTVLG DVQLPPWADG DPRKFISLHR KALESDFVSA NLHHWIDLIF 2770 2780 2790 2800 2810 2820 GYKQQGPAAV DAVNIFHPYF YGDRMDLSSI TDPLIKSTIL GFVSNFGQVP KQLFTKPHPA 2830 2840 2850 2860 2870 2880 RTAAGKPLPG KDVSTPVSLP GHPQPFFYSL QSLRPSQVTV KDMYLFSLGS ESPKGAIGHI 2890 2900 2910 2920 2930 2940 VSTEKTILAV ERNKVLLPPL WNRTFSWGFD DFSCCLGSYG SDKVLMTFEN LAAWGRCLCA 2950 2960 2970 2980 2990 3000 VCPSPTTIVT SGTSTVVCVW ELSMTKGRPR GLRLRQALYG HTQAVTCLAA SVTFSLLVSG 3010 3020 3030 3040 3050 3060 SQDCTCILWD LDHLTHVTRL PAHREGISAI TISDVSGTIV SCAGAHLSLW NVNGQPLASI 3070 3080 3090 3100 3110 3120 TTAWGPEGAI TCCCLMEGPA WDTSQIIITG SQDGMVRVWK TEDVKMSVPG RPAGEEPPAQ 3130 3140 3150 3160 3170 3180 PPSPRGHKWE KNLALSRELD VSIALTGKPS KTSPAVTALA VSRNHTKLLV GDERGRIFCW SADG
	Isoform 2 [UniParc]. Checksum: EC85C73B9A9BBE16	FASTA	654	73,196
	10 20 30 40 50 60 MEAEDLSKAE DRNEDPGSKN EGQLAAVQPD VPHGGQSSSP TALWDMLERK FLEYQQLTHK 70 80 90 100 110 120 SPIERQKSLL SLLPLFLKAW EHSVGIICFP SLQRLAEDVS DQLAQQLQKA LVGKPAEQAR 130 140 150 160 170 180 LAAGQLLWWK GDVDQDGYLL LKSVYVLTGT DSETLGRVAE SGLPALLLQC LYLFFVFPLD 190 200 210 220 230 240 KDELLESDLQ VQKMFVQMLL NICSDSQGLE GLLSGSELQS LLIATTCLRE HSCCFWKEPT 250 260 270 280 290 300 FCVLRAISKA QNLSIIQYLQ ATDCVRLSLQ NLSRLTDTLP APEVSEAVSL ILGFVKDSYP 310 320 330 340 350 360 VSSALFLEFE NSEGYPLLLK VLLRYDGLTQ SEVDPHLEEL LGLVVWLTTC GRSELKVFDS 370 380 390 400 410 420 ITYPQLEGFK FHHEASGVTV KNLQAFQVLQ NVFHKASDSV LCIQVLSVIR TMWAWNARNF 430 440 450 460 470 480 FLLEWTLQPI SQFVEIMPLK PAPVQEHFFQ LLEALVFELH YVPHEILRKV QHLIKESPGP 490 500 510 520 530 540 SCTLMALQSI LSIAGGDPLF TDIFRDSGLL GLLLAQLRKQ AKIMRKSGNK VSTPGVQDPE 550 560 570 580 590 600 RELTCVMLRI VVTLLKGSVR NAVVLKDHGM VPFIKIFLDD ECYREASLSI LEQLSAINAE 610 620 630 640 650 EYMSIIVGAL CSSTQGELQL KLDLLKVISS PPLRLASLWI CTKRSTFAQA FVFM
	Isoform 3 [UniParc]. Checksum: 534C48ABE2A94BB1	FASTA	1,042	114,924
	10 20 30 40 50 60 MEAEDLSKAE DRNEDPGSKN EGQLAAVQPD VPHGGQSSSP TALWDMLERK FLEYQQLTHK 70 80 90 100 110 120 SPIERQKSLL SLLPLFLKAW EHSVGIICFP SLQRLAEDVS DQLAQQLQKA LVGKPAEQAR 130 140 150 160 170 180 LAAGQLLWWK GDVDQDGYLL LKSVYVLTGT DSETLGRVAE SGLPALLLQC LYLFFVFPLD 190 200 210 220 230 240 KDELLESDLQ VQKMFVQMLL NICSDSQGLE GLLSGSELQS LLIATTCLRE HSCCFWKEPT 250 260 270 280 290 300 FCVLRAISKA QNLSIIQYLQ ATDCVRLSLQ NLSRLTDTLP APEVSEAVSL ILGFVKDSYP 310 320 330 340 350 360 VSSALFLEFE NSEGYPLLLK VLLRYDGLTQ SEVDPHLEEL LGLVVWLTTC GRSELKVFDS 370 380 390 400 410 420 ITYPQLEGFK FHHEASGVTV KNLQAFQVLQ NVFHKASDSV LCIQVLSVIR TMWAWNARNF 430 440 450 460 470 480 FLLEWTLQPI SQFVEIMPLK PAPVQEHFFQ LLEALVFELH YVPHEILRKV QHLIKESPGP 490 500 510 520 530 540 SCTLMALQSI LSIAGGDPLF TDIFRDSGLL GLLLAQLRKQ AKIMRKSGNK VSTPGVQDPE 550 560 570 580 590 600 RELTCVMLRI VVTLLKGSVR NAVVLKDHGM VPFIKIFLDD ECYREASLSI LEQLSAINAE 610 620 630 640 650 660 EYMSIIVGAL CSSTQGELQL KLDLLKSLLR ILVTPKGRAA FRVSSGFNGL LSLLSDLEGS 670 680 690 700 710 720 LQEPPLQAWG AVSPRQTLEL VLYTLCAVSA ALHWDPVNGY FFRRNGLFEK LAEDLCLLGC 730 740 750 760 770 780 FGALEEEGNL LRSWVDTKAR PFADLLGTAF SSSGSLPPRI QSCLQILGFL DSMASGTLHL 790 800 810 820 830 840 RGDLKESLRT KQGPVVDVQK GETGSDPQRN FKQWPDLEER MDEGDAAIMH PGVVCIMVRL 850 860 870 880 890 900 LPRLYHEDHP QLSEEIQCSL ASHIQSLVKS EKNRQVMCEA GLLGTLMASC HRALVTSGSP 910 920 930 940 950 960 LHSRLIRIFE KLASQAIEPD VLRQFLGLGI PSSLSATTKI LDSSHTHRGN PGCSGSQTAQ 970 980 990 1000 1010 1020 GLAEGPWPAA PDAGLHPGVT QAPQPLGESQ DSTTALQTAL SLISMTFPAC WKPNIWKDNL 1030 1040 AQKPVAGDAA QCNIFPPASS VL
	Isoform 4 [UniParc]. Checksum: D7F5CFF17F2AADA1	FASTA	3,176	352,667
	10 20 30 40 50 60 MEAEDLSKAE DRNEDPGSKN EGQLAAVQPD VPHGGQSSSP TALWDMLERK FLEYQQLTHK 70 80 90 100 110 120 SPIERQKSLL SLLPLFLKAW EHSVGIICFP SLQRLAEDVS DQLAQQLQKA LVGKPAEQAR 130 140 150 160 170 180 LAAGQLLWWK GDVDQDGYLL LKSVYVLTGT DSETLGRVAE SGLPALLLQC LYLFFVFPLD 190 200 210 220 230 240 KDELLESDLQ VQKMFVQMLL NICSDSQGLE GLLSGSELQS LLIATTCLRE HSCCFWKEPT 250 260 270 280 290 300 FCVLRAISKA QNLSIIQYLQ ATDCVRLSLQ NLSRLTDTLP APEVSEAVSL ILGFVKDSYP 310 320 330 340 350 360 VSSALFLEFE NSEGYPLLLK VLLRYDGLTQ SEVDPHLEEL LGLVVWLTTC GRSELKVFDS 370 380 390 400 410 420 ITYPQLEGFK FHHEASGVTV KNLQAFQVLQ NVFHKASDSV LCIQVLSVIR TMWAWNARNF 430 440 450 460 470 480 FLLEWTLQPI SQFVEIMPLK PAPVQEHFFQ LLEALVFELH YVPHEILRKV QHLIKESPGP 490 500 510 520 530 540 SCTLMALQSI LSIAGGDPLF TDIFRDSGLL GLLLAQLRKQ AKIMRKSGNK VSTPGVQDPE 550 560 570 580 590 600 RELTCVMLRI VVTLLKGSVR NAVVLKDHGM VPFIKIFLDD ECYREASLSI LEQLSAINAE 610 620 630 640 650 660 EYMSIIVGAL CSSTQGELQL KLDLLKSLLR ILVTPKGRAA FRVSSGFNGL LSLLSDLEGS 670 680 690 700 710 720 LQEPPLQAWG AVSPRQTLEL VLYTLCAVSA ALHWDPVNGY FFRRNGLFEK LAEDLCLLGC 730 740 750 760 770 780 FGALEEEGNL LRSWVDTKAR PFADLLGTAF SSSGSLPPRI QSCLQILGFL DSMASGTLHL 790 800 810 820 830 840 RGDLKESLRT KQGPVVDVQK GETGSDPQRN FKQWPDLEER MDEGDAAIMH PGVVCIMVRL 850 860 870 880 890 900 LPRLYHEDHP QLSEEIQCSL ASHIQSLVKS EKNRQVMCEA GLLGTLMASC HRALVTSGSP 910 920 930 940 950 960 LHSRLIRIFE KLASQAIEPD VLRQFLGLGI PSSLSATTKI LDSSHTHRGN PGCSGSQTAQ 970 980 990 1000 1010 1020 GLAEGPWPAA PDAGLHPGVT QAPQPLGESQ DSTTALQTAL SLISMTSPRN LQPQRAALAP 1030 1040 1050 1060 1070 1080 SFVEFDMSVE GYGCLFIPTL STVMGTSTEY SVSGGIGTGA TRPFPPPGGL TFSCWFLISR 1090 1100 1110 1120 1130 1140 HGAATEGHPL RFLTLVRHLA RTEQPFVCFS VSLCPDDLSL VVSTEEKEFQ PLDVMEPEDD 1150 1160 1170 1180 1190 1200 SEPSAGCQLQ VRCGQLLACG QWHHLAVVVT KEMKRHCTVS TCLDGQVIGS AKMLYIQALP 1210 1220 1230 1240 1250 1260 GPFLSMDPSA FVDVYGYIAT PRVWKQKSSL IWRLGPTYLF EEAISMETLE VINKLGPRYC 1270 1280 1290 1300 1310 1320 GNFQAVHVQG EDLDSEATPF VAEERVSFGL HIASSSITSV ADIRNAYNEV DSRLIAKEMN 1330 1340 1350 1360 1370 1380 ISSRDNAMPV FLLRNCAGHL SGSLRTIGAV AVGQLGVRVF HSSPAASSLD FIGGPAILLG 1390 1400 1410 1420 1430 1440 LISLATDDHT MYAAVKVLHS VLTSNAMCDF LMQHICGYQI MAFLLRKKAS LLNHRIFQLI 1450 1460 1470 1480 1490 1500 LSVAGTVELG FRSSAITNTG VFQHILCNFE LWMNTADNLE LSLFSHLLEI LQSPREGPRN 1510 1520 1530 1540 1550 1560 AEAAHQAQLI PKLIFLFNEP SLIPSKISTI IGILACQLRG HFSTQDLLRI GLFVVYTLKP 1570 1580 1590 1600 1610 1620 SSVNERQICM DGALDPSLPA GSQTSGKTIW LRNQLLEMLL SVISSPQLHL SSESKEEMFL 1630 1640 1650 1660 1670 1680 KLGPDWFLLL LQGHLHASTT VLALKLLLYF LASPSLRTRF RDGLCAGSWV ERSTEGVDIV 1690 1700 1710 1720 1730 1740 MDNLKSQSPL PEQSPCLLPG FRVLNDFLAH HVHIPEVYLI VSTFFLQTPL TELMDGPKDS 1750 1760 1770 1780 1790 1800 LDAMLQWLLQ RHHQEEVLQA GLCTEGALLL LEMLKATMSQ PLAGSEDGAW AQTFPASVLQ 1810 1820 1830 1840 1850 1860 FLSLVHRTYP QDPAWRAPEF LQTLAIAAFP LGAQKGVGAE STRNTSSPEA AAEGDSTVEG 1870 1880 1890 1900 1910 1920 LQAPTKAHPA RRKLREFTQL LLRELLLGAS SPKQWLPLEV LLEASPDHAT SQQKRDFQSE 1930 1940 1950 1960 1970 1980 VLLSAMELFH MTSGGDAAMF RDGKEPQPSA EAAAAPSLAN ISCFTQKLVE KLYSGMFSAD 1990 2000 2010 2020 2030 2040 PRHILLFILE HIMVVIETAS SQRDTVLSTL YSSLNKVILY CLSKPQQSLS ECLGLLSILG 2050 2060 2070 2080 2090 2100 FLQEHWDVVF ATYNSNISFL LCLMHCLLLL NERSYPEGFG LEPKPRMSTY HQVFLSPNED 2110 2120 2130 2140 2150 2160 VKEKREDLPS LSDVQHNIQK TVQTLWQQLV AQRQQTLEDA FKIDLSVKPG EREVKIEEVT 2170 2180 2190 2200 2210 2220 PLWEETMLKA WQHYLASEKK SLASRSNVAH HSKVTLWSGS LSSAMKLMPG RQAKDPECKT 2230 2240 2250 2260 2270 2280 EDFVSCIENY RRRGQELYAS LYKDHVQRRK CGNIKAANAW ARIQEQLFGE LGLWSQGEET 2290 2300 2310 2320 2330 2340 KPCSPWELDW REGPARMRKR IKRLSPLEAL SSGRHKESQD KNDHISQTNA ENQDELTLRE 2350 2360 2370 2380 2390 2400 AEGEPDEVGV DCTQLTFFPA LHESLHSEDF LELCRERQVI LQELLDKEKV TQKFSLVIVQ 2410 2420 2430 2440 2450 2460 GHLVSEGVLL FGHQHFYICE NFTLSPTGDV YCTRHCLSNI SDPFIFNLCS KDRSTDHYSC 2470 2480 2490 2500 2510 2520 QCHSYADMRE LRQARFLLQD IALEIFFHNG YSKFLVFYNN DRSKAFKSFC SFQPSLKGKA 2530 2540 2550 2560 2570 2580 TSEDTLSLRR YPGSDRIMLQ KWQKRDISNF EYLMYLNTAA GRTCNDYMQY PVFPWVLADY 2590 2600 2610 2620 2630 2640 TSETLNLANP KIFRDLSKPM GAQTKERKLK FIQRFKEVEK TEGDMTVQCH YYTHYSSAII 2650 2660 2670 2680 2690 2700 VASYLVRMPP FTQAFCALQG GSFDVADRMF HSVKSTWESA SRENMSDVRE LTPEFFYLPE 2710 2720 2730 2740 2750 2760 FLTNCNGVEF GCMQDGTVLG DVQLPPWADG DPRKFISLHR KALESDFVSA NLHHWIDLIF 2770 2780 2790 2800 2810 2820 GYKQQGPAAV DAVNIFHPYF YGDRMDLSSI TDPLIKSTIL GFVSNFGQVP KQLFTKPHPA 2830 2840 2850 2860 2870 2880 RTAAGKPLPG KDVSTPVSLP GHPQPFFYSL QSLRPSQVTV KDMYLFSLGS ESPKGAIGHI 2890 2900 2910 2920 2930 2940 VSTEKTILAV ERNKVLLPPL WNRTFSWGFD DFSCCLGSYG SDKVLMTFEN LAAWGRCLCA 2950 2960 2970 2980 2990 3000 VCPSPTTIVT SGTSTVVCVW ELSMTKGRPR GLRLRQALYG HTQAVTCLAA SVTFSLLVSG 3010 3020 3030 3040 3050 3060 SQDCTCILWD LDHLTHVTRL PAHREGISAI TISDVSGTIV SCAGAHLSLW NVNGQPLASI 3070 3080 3090 3100 3110 3120 TTAWGPEGAI TCCCLMEGPA WDTSQIIITG SQDGMVRVWK TEDVKMSVPG LQMGRKREAA 3130 3140 3150 3160 3170 EALAQQCQAE GGRGDWGLSS AYRRNPQGLL PHSSQGRASG NHSSAAQPSP WPMGLL
	Isoform 5 [UniParc]. Checksum: 73B0497433628D5D	FASTA	2,920	325,232
	10 20 30 40 50 60 MEAEDLSKAE DRNEDPGSKN EGQLAAVQPD VPHGGQSSSP TALWDMLERK FLEYQQLTHK 70 80 90 100 110 120 SPIERQKSLL SLLPLFLKAW EHSVGIICFP SLQRLAEDVS DQLAQQLQKA LVGKPAEQAR 130 140 150 160 170 180 LAAGQLLWWK GDVDQDGYLL LKSVYVLTGT DSETLGRVAE SGLPALLLQC LYLFFVFPLD 190 200 210 220 230 240 KDELLESDLQ VQKMFVQMLL NICSDSQGLE GLLSGSELQS LLIATTCLRE HSCCFWKEPT 250 260 270 280 290 300 FCVLRAISKA QNLSIIQYLQ ATDCVRLSLQ NLSRLTDTLP APEVSEAVSL ILGFVKDSYP 310 320 330 340 350 360 VSSALFLEFE NSEGYPLLLK VLLRYDGLTQ SEVDPHLEEL LGLVVWLTTC GRSELKVFDS 370 380 390 400 410 420 ITYPQLEGFK FHHEASGVTV KNLQAFQVLQ NVFHKASDSV LCIQVLSVIR TMWAWNARNF 430 440 450 460 470 480 FLLEWTLQPI SQFVEIMPLK PAPVQEHFFQ LLEALVFELH YVPHEILRKV QHLIKESPGP 490 500 510 520 530 540 SCTLMALQSI LSIAGGDPLF TDIFRDSGLL GLLLAQLRKQ AKIMRKSGNK VSTPGVQDPE 550 560 570 580 590 600 RELTCVMLRI VVTLLKGSVR NAVVLKDHGM VPFIKIFLDD ECYREASLSI LEQLSAINAE 610 620 630 640 650 660 EYMSIIVGAL CSSTQGELQL KLDLLKSLLR ILVTPKGRAA FRVSSGFNGL LSLLSDLEGS 670 680 690 700 710 720 LQEPPLQAWG AVSPRQTLEL VLYTLCAVSA ALHWDPVNGY FFRRNGLFEK LAEDLCLLGC 730 740 750 760 770 780 FGALEEEGNL LRSWVDTKAR PFADLLGTAF SSSGSLPPRI QSCLQILGFL DSMASGTLHL 790 800 810 820 830 840 RGDLKESLRT KQGPVVDVQK GETGSDPQRN FKQWPDLEER MDEGDAAIMH PGVVCIMVRL 850 860 870 880 890 900 LPRLYHEDHP QLSEEIQCSL ASHIQSLVKS EKNRQVMCEA GLLGTLMASC HRALVTSGSP 910 920 930 940 950 960 LHSRLIRIFE KLASQAIEPD VLRQFLGLGI PSSLSATTKI LDSSHTHRGN PGCSGSQTAQ 970 980 990 1000 1010 1020 GLAEGPWPAA PDAGLHPGVT QAPQPLGESQ DSTTALQTAL SLISMTSPRN LQPQRAALAP 1030 1040 1050 1060 1070 1080 SFVEFDMSVE GYGCLFIPTL STVMGTSTEY SVSGGIGTGA TRPFPPPGGL TFSCWFLISR 1090 1100 1110 1120 1130 1140 HGAATEGHPL RFLTLVRHLA RTEQPFVCFS VSLCPDDLSL VVSTEEKEFQ PLDVMEPEDD 1150 1160 1170 1180 1190 1200 SEPSAGCQLQ VRCGQLLACG QWHHLAVVVT KEMKRHCTVS TCLDGQVIGS AKMLYIQALP 1210 1220 1230 1240 1250 1260 GPFLSMDPSA FVDVYGYIAT PRVWKQKSSL IWRLGPTYLF EEAISMETLE VINKLGPRYC 1270 1280 1290 1300 1310 1320 GNFQAVHVQG EDLDSEATPF VAEERVSFGL HIASSSITSV ADIRNAYNEV DSRLIAKEMN 1330 1340 1350 1360 1370 1380 ISSRDNAMPV FLLRNCAGHL SGSLRTIGAV AVGQLGVRVF HSSPAASSLD FIGGPAILLG 1390 1400 1410 1420 1430 1440 LISLATDDHT MYAAVKVLHS VLTSNAMCDF LMQHICGYQI MAFLLRKKAS LLNHRIFQLI 1450 1460 1470 1480 1490 1500 LSVAGTVELG FRSSAITNTG VFQHILCNFE LWMNTADNLE LSLFSHLLEI LQSPREGPRN 1510 1520 1530 1540 1550 1560 AEAAHQAQLI PKLIFLFNEP SLIPSKISTI IGILACQLRG HFSTQDLLRI GLFVVYTLKP 1570 1580 1590 1600 1610 1620 SSVNERQICM DGALDPSLPA GSQTSGKTIW LRNQLLEMLL SVISSPQLHL SSESKEEMFL 1630 1640 1650 1660 1670 1680 KLGPDWFLLL LQGHLHASTT VLALKLLLYF LASPSLRTRF RDGLCAGSWV ERSTEGVDIV 1690 1700 1710 1720 1730 1740 MDNLKSQSPL PEQSPCLLPG FRVLNDFLAH HVHIPEVYLI VSTFFLQTPL TELMDGPKDS 1750 1760 1770 1780 1790 1800 LDAMLQWLLQ RHHQEEVLQA GLCTEGALLL LEMLKATMSQ PLAGSEDGAW AQTFPASVLQ 1810 1820 1830 1840 1850 1860 FLSLVHRTYP QDPAWRAPEF LQTLAIAAFP LGAQKGVGAE STRNTSSPEA AAEGDSTVEG 1870 1880 1890 1900 1910 1920 LQAPTKAHPA RRKLREFTQL LLRELLLGAS SPKQWLPLEV LLEASPDHAT SQQKRDFQSE 1930 1940 1950 1960 1970 1980 VLLSAMELFH MTSGGDAAMF RDGKEPQPSA EAAAAPSLAN ISCFTQKLVE KLYSGMFSAD 1990 2000 2010 2020 2030 2040 PRHILLFILE HIMVVIETAS SQRDTVLSTL YSSLNKVILY CLSKPQQSLS ECLGLLSILG 2050 2060 2070 2080 2090 2100 FLQEHWDVVF ATYNSNISFL LCLMHCLLLL NERSYPEGFG LEPKPRMSTY HQVFLSPNED 2110 2120 2130 2140 2150 2160 VKEKREDLPS LSDVQHNIQK TVQTLWQQLV AQRQQTLEDA FKIDLSVKPG EREVKIEEVT 2170 2180 2190 2200 2210 2220 PLWEETMLKA WQHYLASEKK SLASRSNVAH HSKVTLWSGS LSSAMKLMPG RQAKDPECKT 2230 2240 2250 2260 2270 2280 EDFVSCIENY RRRGQELYAS LYKDHVQRRK CGNIKAANAW ARIQEQLFGE LGLWSQGEET 2290 2300 2310 2320 2330 2340 KPCSPWELDW REGPARMRKR IKRLSPLEAL SSGRHKESQD KNDHISQTNA ENQDELTLRE 2350 2360 2370 2380 2390 2400 AEGEPDEVGV DCTQLTFFPA LHESLHSEDF LELCRERQVI LQELLDKEKV TQKFSLVIVQ 2410 2420 2430 2440 2450 2460 GHLVSEGVLL FGHQHFYICE NFTLSPTGDV YCTRHCLSNI SDPFIFNLCS KDRSTDHYSC 2470 2480 2490 2500 2510 2520 QCHSYADMRE LRQARFLLQD IALEIFFHNG YSKFLVFYNN DRSKAFKSFC SFQPSLKGKA 2530 2540 2550 2560 2570 2580 TSEDTLSLRR YPGSDRIMLQ KWQKRDISNF EYLMYLNTAA GRTCNDYMQY PVFPWVLADY 2590 2600 2610 2620 2630 2640 TSETLNLANP KIFRDLSKPM GAQTKERKLK FIQRFKEVEK TEGDMTVQCH YYTHYSSAII 2650 2660 2670 2680 2690 2700 VASYLVRMPP FTQAFCALQG GSFDVADRMF HSVKSTWESA SRENMSDVRE LTPEFFYLPE 2710 2720 2730 2740 2750 2760 FLTNCNGVEF GCMQDGTVLG DVQLPPWADG DPRKFISLHR KALESDFVSA NLHHWIDLIF 2770 2780 2790 2800 2810 2820 GYKQQGPAAV DAVNIFHPYF YGDRMDLSSI TDPLIKSTIL GFVSNFGQVP KQLFTKPHPA 2830 2840 2850 2860 2870 2880 RTAAGKPLPG KDVSTPVSLP GHPQPFFYSL QSLRPSQVTV KGDSLAMHCL VSCPRVVPSV 2890 2900 2910 2920 AGFLWRSSTT YLGKVLGTDF EWLHLQSQPD SRGVSSLGSV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2587-3184 (ISOFORM 5), VARIANT PRO-214. Tissue: Spleen.
[2]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed: 15164054] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2286-3184 (ISOFORM 1), VARIANT ASN-2527. Tissue: B-cell, Brain and Lymph.
[4]	"The nucleotide sequence of a long cDNA clone isolated from human spleen." Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O. Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1290-3184 (ISOFORM 4), VARIANT ASN-2527. Tissue: Spleen.
[5]	"Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Nakayama M., Hirosawa M., Ohara O. DNA Res. 7:273-281(2000) [PubMed: 10997877] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1915-3184 (ISOFORM 1), VARIANT ASN-2527. Tissue: Brain.
[6]	"Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico." Katoh M., Katoh M. Int. J. Mol. Med. 14:333-338(2004) [PubMed: 15254788] [Abstract] Cited for: IDENTIFICATION.
[7]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed: 21269460] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK024502 mRNA. Translation: BAB15792.1. AK127650 mRNA. Translation: BAC87073.1. AC035139 Genomic DNA. No translation available. AC060234 Genomic DNA. No translation available. AC068898 Genomic DNA. No translation available. BC015694 mRNA. Translation: AAH15694.2. BC034937 mRNA. Translation: AAH34937.1. BC047574 mRNA. Translation: AAH47574.1. AK074085 mRNA. Translation: BAB84911.1. AB046827 mRNA. Translation: BAB13433.1.
IPI	IPI00472883. IPI00550834. IPI00641442. IPI00887548. IPI00914858.
RefSeq	NP_065996.1. NM_020945.1.
UniGene	Hs.287379.
3D structure databases
ProteinModelPortal	Q6ZS81.
SMR	Q6ZS81. Positions 2389-2821, 2904-3183.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6ZS81. 1 interaction.
STRING	Q6ZS81.
PTM databases
PhosphoSite	Q6ZS81.
Polymorphism databases
DMDM	215274123.
Proteomic databases
PRIDE	Q6ZS81.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000325239; ENSP00000320563; ENSG00000128815.
GeneID	57705.
KEGG	hsa:57705.
UCSC	uc001jgy.2. human.
Organism-specific databases
CTD	57705.
GeneCards	GC10P049892.
HGNC	HGNC:29323. WDFY4.
HPA	HPA040634.
MIM	613316. gene.
neXtProt	NX_Q6ZS81.
PharmGKB	PA134967634.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
GeneTree	ENSGT00600000084290.
OMA	IATPRVW.
PhylomeDB	Q6ZS81.
Gene expression databases
ArrayExpress	Q6ZS81.
Bgee	Q6ZS81.
CleanEx	HS_WDFY4.
Genevestigator	Q6ZS81.
GermOnline	ENSG00000128815. Homo sapiens.
Family and domain databases
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR000409. BEACH_dom. IPR023362. PH-BEACH_dom. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR011046. WD40_repeat-like_dom. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. [Graphical view]
Gene3D	G3DSA:1.25.10.10. ARM-like. 2 hits. G3DSA:1.10.1540.10. Beige_BEACH. 1 hit. G3DSA:2.30.29.40. G3DSA:2.30.29.40. 1 hit. G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 2 hits.
Pfam	PF02138. Beach. 1 hit. PF00400. WD40. 2 hits. [Graphical view]
SMART	SM01026. Beach. 1 hit. SM00320. WD40. 5 hits. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 1 hit. SSF81837. Beige_BEACH. 1 hit. SSF50978. WD40_like. 1 hit.
PROSITE	PS50197. BEACH. 1 hit. PS00678. WD_REPEATS_1. 1 hit. PS50082. WD_REPEATS_2. 2 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

WDFY4_HUMAN

Accession

Primary (citable) accession number: Q6ZS81
Secondary accession number(s): B9ZVP2 , Q86WZ4, Q8N4A3, Q8TEN7, Q96BE1, Q9H7H8, Q9HCG5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2006
Last sequence update:	November 25, 2008
Last modified:	January 25, 2012
This is version 65 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.