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Q6ZRY4

- RBPS2_HUMAN

UniProt

Q6ZRY4 - RBPS2_HUMAN

Protein

RNA-binding protein with multiple splicing 2

Gene

RBPMS2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. nucleic acid binding Source: InterPro
    2. nucleotide binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA-binding protein with multiple splicing 2
    Gene namesi
    Name:RBPMS2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:19098. RBPMS2.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134871904.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 209208RNA-binding protein with multiple splicing 2PRO_0000274909Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylserine1 Publication

    Keywords - PTMi

    Acetylation

    Proteomic databases

    PaxDbiQ6ZRY4.
    PRIDEiQ6ZRY4.

    PTM databases

    PhosphoSiteiQ6ZRY4.

    Expressioni

    Gene expression databases

    ArrayExpressiQ6ZRY4.
    BgeeiQ6ZRY4.
    CleanExiHS_RBPMS2.
    GenevestigatoriQ6ZRY4.

    Organism-specific databases

    HPAiHPA058366.

    Interactioni

    Protein-protein interaction databases

    BioGridi131505. 2 interactions.
    STRINGi9606.ENSP00000300069.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6ZRY4.
    SMRiQ6ZRY4. Positions 27-106.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini31 – 10878RRMPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG255204.
    HOGENOMiHOG000017369.
    HOVERGENiHBG069897.
    InParanoidiQ6ZRY4.
    OMAiSRQPVGF.
    PhylomeDBiQ6ZRY4.
    TreeFamiTF351070.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view]
    PfamiPF00076. RRM_1. 1 hit.
    [Graphical view]
    SMARTiSM00360. RRM. 1 hit.
    [Graphical view]
    PROSITEiPS50102. RRM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6ZRY4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNLKPDGEH GGSTGTGSGA GSGGALEEEV RTLFVSGLPV DIKPRELYLL    50
    FRPFKGYEGS LIKLTARQPV GFVIFDSRAG AEAAKNALNG IRFDPENPQT 100
    LRLEFAKANT KMAKSKLMAT PNPSNVHPAL GAHFIARDPY DLMGAALIPA 150
    SPEAWAPYPL YTTELTPAIS HAAFTYPTAT AAAAALHAQV RWYPSSDTTQ 200
    QGWKYRQFC 209
    Length:209
    Mass (Da):22,497
    Last modified:July 5, 2004 - v1
    Checksum:iE7924D0CD3AD860C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY369207 mRNA. Translation: AAQ73311.1.
    AK127873 mRNA. Translation: BAC87172.1.
    CCDSiCCDS32271.1.
    RefSeqiNP_919248.1. NM_194272.1.
    UniGeneiHs.436518.

    Genome annotation databases

    EnsembliENST00000300069; ENSP00000300069; ENSG00000166831.
    GeneIDi348093.
    KEGGihsa:348093.
    UCSCiuc002anq.3. human.

    Polymorphism databases

    DMDMi74762401.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY369207 mRNA. Translation: AAQ73311.1 .
    AK127873 mRNA. Translation: BAC87172.1 .
    CCDSi CCDS32271.1.
    RefSeqi NP_919248.1. NM_194272.1.
    UniGenei Hs.436518.

    3D structure databases

    ProteinModelPortali Q6ZRY4.
    SMRi Q6ZRY4. Positions 27-106.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 131505. 2 interactions.
    STRINGi 9606.ENSP00000300069.

    PTM databases

    PhosphoSitei Q6ZRY4.

    Polymorphism databases

    DMDMi 74762401.

    Proteomic databases

    PaxDbi Q6ZRY4.
    PRIDEi Q6ZRY4.

    Protocols and materials databases

    DNASUi 348093.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000300069 ; ENSP00000300069 ; ENSG00000166831 .
    GeneIDi 348093.
    KEGGi hsa:348093.
    UCSCi uc002anq.3. human.

    Organism-specific databases

    CTDi 348093.
    GeneCardsi GC15M065032.
    HGNCi HGNC:19098. RBPMS2.
    HPAi HPA058366.
    neXtProti NX_Q6ZRY4.
    PharmGKBi PA134871904.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG255204.
    HOGENOMi HOG000017369.
    HOVERGENi HBG069897.
    InParanoidi Q6ZRY4.
    OMAi SRQPVGF.
    PhylomeDBi Q6ZRY4.
    TreeFami TF351070.

    Miscellaneous databases

    ChiTaRSi RBPMS2. human.
    GenomeRNAii 348093.
    NextBioi 99336.
    PROi Q6ZRY4.

    Gene expression databases

    ArrayExpressi Q6ZRY4.
    Bgeei Q6ZRY4.
    CleanExi HS_RBPMS2.
    Genevestigatori Q6ZRY4.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR000504. RRM_dom.
    [Graphical view ]
    Pfami PF00076. RRM_1. 1 hit.
    [Graphical view ]
    SMARTi SM00360. RRM. 1 hit.
    [Graphical view ]
    PROSITEi PS50102. RRM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Huang C.Q., Wu S.L., Liu S.
      Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Prostate.
    3. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiRBPS2_HUMAN
    AccessioniPrimary (citable) accession number: Q6ZRY4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 6, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3