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Q6ZRY4 (RBPS2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-binding protein with multiple splicing 2
Gene names
Name:RBPMS2
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 RRM (RNA recognition motif) domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.3
Chain2 – 209208RNA-binding protein with multiple splicing 2
PRO_0000274909

Regions

Domain31 – 10878RRM

Amino acid modifications

Modified residue21N-acetylserine Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q6ZRY4 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: E7924D0CD3AD860C

FASTA20922,497
        10         20         30         40         50         60 
MSNLKPDGEH GGSTGTGSGA GSGGALEEEV RTLFVSGLPV DIKPRELYLL FRPFKGYEGS 

        70         80         90        100        110        120 
LIKLTARQPV GFVIFDSRAG AEAAKNALNG IRFDPENPQT LRLEFAKANT KMAKSKLMAT 

       130        140        150        160        170        180 
PNPSNVHPAL GAHFIARDPY DLMGAALIPA SPEAWAPYPL YTTELTPAIS HAAFTYPTAT 

       190        200 
AAAAALHAQV RWYPSSDTTQ QGWKYRQFC 

« Hide

References

« Hide 'large scale' references
[1]Huang C.Q., Wu S.L., Liu S.
Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Prostate.
[3]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY369207 mRNA. Translation: AAQ73311.1.
AK127873 mRNA. Translation: BAC87172.1.
RefSeqNP_919248.1. NM_194272.1.
UniGeneHs.436518.

3D structure databases

ProteinModelPortalQ6ZRY4.
SMRQ6ZRY4. Positions 27-106.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid131505. 2 interactions.
STRING9606.ENSP00000300069.

PTM databases

PhosphoSiteQ6ZRY4.

Polymorphism databases

DMDM74762401.

Proteomic databases

PaxDbQ6ZRY4.
PRIDEQ6ZRY4.

Protocols and materials databases

DNASU348093.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000300069; ENSP00000300069; ENSG00000166831.
GeneID348093.
KEGGhsa:348093.
UCSCuc002anq.3. human.

Organism-specific databases

CTD348093.
GeneCardsGC15M065032.
HGNCHGNC:19098. RBPMS2.
HPAHPA058366.
neXtProtNX_Q6ZRY4.
PharmGKBPA134871904.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG255204.
HOGENOMHOG000017369.
HOVERGENHBG069897.
InParanoidQ6ZRY4.
OMASRQPVGF.
PhylomeDBQ6ZRY4.
TreeFamTF351070.

Gene expression databases

ArrayExpressQ6ZRY4.
BgeeQ6ZRY4.
CleanExHS_RBPMS2.
GenevestigatorQ6ZRY4.

Family and domain databases

Gene3D3.30.70.330. 1 hit.
InterProIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTSM00360. RRM. 1 hit.
[Graphical view]
PROSITEPS50102. RRM. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSRBPMS2. human.
GenomeRNAi348093.
NextBio99336.
PROQ6ZRY4.

Entry information

Entry nameRBPS2_HUMAN
AccessionPrimary (citable) accession number: Q6ZRY4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: July 5, 2004
Last modified: March 19, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 15

Human chromosome 15: entries, gene names and cross-references to MIM