Q6ZRY4 (RBPS2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
RNA-binding protein with multiple splicing 2

Gene names

Name:

RBPMS2

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 RRM (RNA recognition motif) domain.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	nucleic acid binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 209	209	RNA-binding protein with multiple splicing 2		PRO_0000274909
Regions
	Domain	31 – 108	78	RRM

Sequences

	Sequence		Length	Mass (Da)
	Q6ZRY4 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: E7924D0CD3AD860C	FASTA	209	22,497
	10 20 30 40 50 60 MSNLKPDGEH GGSTGTGSGA GSGGALEEEV RTLFVSGLPV DIKPRELYLL FRPFKGYEGS 70 80 90 100 110 120 LIKLTARQPV GFVIFDSRAG AEAAKNALNG IRFDPENPQT LRLEFAKANT KMAKSKLMAT 130 140 150 160 170 180 PNPSNVHPAL GAHFIARDPY DLMGAALIPA SPEAWAPYPL YTTELTPAIS HAAFTYPTAT 190 200 AAAAALHAQV RWYPSSDTTQ QGWKYRQFC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Huang C.Q., Wu S.L., Liu S. Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Prostate.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY369207 mRNA. Translation: AAQ73311.1. AK127873 mRNA. Translation: BAC87172.1.
IPI	IPI00238688.
RefSeq	NP_919248.1. NM_194272.1.
UniGene	Hs.436518.
3D structure databases
HSSP	HSSP built from PDB template 2U1A based on UniProtKB P09012.
ProteinModelPortal	Q6ZRY4.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000300069.
PTM databases
PhosphoSite	Q6ZRY4.
Polymorphism databases
DMDM	74762401.
Proteomic databases
PaxDb	Q6ZRY4.
PRIDE	Q6ZRY4.
Protocols and materials databases
DNASU	348093.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000300069; ENSP00000300069; ENSG00000166831.
GeneID	348093.
KEGG	hsa:348093.
UCSC	uc002anq.3. human.
Organism-specific databases
CTD	348093.
GeneCards	GC15M065032.
HGNC	HGNC:19098. RBPMS2.
neXtProt	NX_Q6ZRY4.
PharmGKB	PA134871904.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG255204.
HOGENOM	HOG000017369.
HOVERGEN	HBG069897.
InParanoid	Q6ZRY4.
OMA	KLTSRQP.
OrthoDB	EOG42RD8G.
PhylomeDB	Q6ZRY4.
Gene expression databases
ArrayExpress	Q6ZRY4.
Bgee	Q6ZRY4.
CleanEx	HS_RBPMS2.
Genevestigator	Q6ZRY4.
Family and domain databases
Gene3D	3.30.70.330. 1 hit.
InterPro	IPR012677. Nucleotide-bd_a/b_plait. IPR000504. RRM_dom. [Graphical view]
Pfam	PF00076. RRM_1. 1 hit. [Graphical view]
SMART	SM00360. RRM. 1 hit. [Graphical view]
PROSITE	PS50102. RRM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	RBPMS2. human.
GenomeRNAi	348093.
NextBio	99336.

Entry information

Entry name

RBPS2_HUMAN

Accession

Primary (citable) accession number: Q6ZRY4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.