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Q6ZRI0

- OTOG_HUMAN

UniProt

Q6ZRI0 - OTOG_HUMAN

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Protein

Otogelin

Gene
OTOG, OTGN
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes By similarity.

GO - Molecular functioni

  1. alpha-L-arabinofuranosidase activity Source: InterPro
  2. structural molecule activity Source: Ensembl

GO - Biological processi

  1. adult locomotory behavior Source: Ensembl
  2. L-arabinose metabolic process Source: InterPro
  3. sensory perception of sound Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Otogelin
Gene namesi
Name:OTOG
Synonyms:OTGN
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:8516. OTOG.

Subcellular locationi

Apical cell membrane; Peripheral membrane protein; Extracellular side By similarity. Secretedextracellular space By similarity
Note: Found in fiber-like structures during the maturation process of the tectorial membrane By similarity.

GO - Cellular componenti

  1. apical plasma membrane Source: UniProtKB-SubCell
  2. cytosol Source: Ensembl
  3. extracellular space Source: UniProtKB-SubCell
  4. proteinaceous extracellular matrix Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane, Secreted

Pathology & Biotechi

Involvement in diseasei

Deafness, autosomal recessive, 18B (DFNB18B) [MIM:614945]: A form of non-syndromic deafness characterized by a moderate hearing impairment, which can be associated with vestibular dysfunction, and a flat to shallow "U" or slightly downsloping shaped audiograms.
Note: The disease is caused by mutations affecting the gene represented in this entry.1 Publication
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti2116 – 21161P → L in DFNB18B. 1 Publication
VAR_069250

Keywords - Diseasei

Deafness, Disease mutation, Non-syndromic deafness

Organism-specific databases

MIMi614945. phenotype.
Orphaneti90636. Autosomal recessive nonsyndromic sensorineural deafness type DFNB.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222 Reviewed predictionAdd
BLAST
Chaini23 – 29252903OtogelinPRO_0000312148Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi106 ↔ 120 By similarity
Disulfide bondi114 ↔ ?126 By similarity
Disulfide bondi128 ↔ 138 By similarity
Glycosylationi914 – 9141N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1478 – 14781N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1612 – 16121N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi2840 ↔ 2889 By similarity
Disulfide bondi2854 ↔ 2903 By similarity
Disulfide bondi2865 ↔ 2920 By similarity
Disulfide bondi2869 ↔ 2922 By similarity

Post-translational modificationi

N-glycosylated By similarity. Not O-glycosylated By similarity.

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ6ZRI0.
PRIDEiQ6ZRI0.

PTM databases

PhosphoSiteiQ6ZRI0.

Expressioni

Gene expression databases

BgeeiQ6ZRI0.
CleanExiHS_OTOG.
GenevestigatoriQ6ZRI0.

Interactioni

Protein-protein interaction databases

BioGridi131110. 1 interaction.
STRINGi9606.ENSP00000382323.

Structurei

3D structure databases

ProteinModelPortaliQ6ZRI0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini102 – 13938EGF-likeAdd
BLAST
Domaini151 – 353203VWFD 1Add
BLAST
Domaini513 – 727215VWFD 2Add
BLAST
Domaini768 – 83265TILAdd
BLAST
Domaini985 – 1187203VWFD 3Add
BLAST
Domaini2111 – 2323213VWFD 4Add
BLAST
Domaini2840 – 292586CTCKAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1482 – 1880399Pro-richAdd
BLAST
Compositional biasi2499 – 2647149Cys-richAdd
BLAST

Sequence similaritiesi

Belongs to the otogelin family.
Contains 1 EGF-like domain.
Contains 4 VWFD domains.

Keywords - Domaini

EGF-like domain, Repeat, Signal

Phylogenomic databases

eggNOGiNOG12793.
HOVERGENiHBG108222.
InParanoidiQ6ZRI0.
OMAiPYFEQCR.
PhylomeDBiQ6ZRI0.
TreeFamiTF300299.

Family and domain databases

InterProiIPR007934. AbfB.
IPR006207. Cys_knot_C.
IPR000742. EG-like_dom.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view]
PfamiPF05270. AbfB. 1 hit.
PF08742. C8. 4 hits.
PF01826. TIL. 1 hit.
PF00094. VWD. 4 hits.
[Graphical view]
SMARTiSM00832. C8. 4 hits.
SM00041. CT. 1 hit.
SM00214. VWC. 2 hits.
SM00216. VWD. 4 hits.
[Graphical view]
SUPFAMiSSF110221. SSF110221. 1 hit.
SSF57567. SSF57567. 4 hits.
PROSITEiPS01225. CTCK_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS51233. VWFD. 4 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6ZRI0-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MGVLASALCW LLCVWLPWGE QAAESLRVQR LGERVVDSGR SGARGMRNVK     50
GMRNGPAQTR VSSSSSHQEA TLAMGDKATV VGGQQAEAPD SVAMSSWERR 100
LHRAKCAPSY LFSCFNGGEC VHPAFCDCRR FNATGPRCQM VYNAGPERDS 150
ICRAWGQHHV ETFDGLYYYL SGKGSYTLVG RHEPEGQSFS IQVHNDPQCG 200
SSPYTCSRAV SLFFVGEQEI HLAKEVTHGG MRVQLPHVMG SARLQQLAGY 250
VIVRHQSAFT LAWDGASAVY IKMSPELLGW THGLCGNNNA DPKDDLVTSS 300
GKLTDDVVEF VHSWQEQAPN QPPGPTTSSL PRPPCLQQNP GTMQGVYEQC 350
EALLRPPFDA CHAYVSPLPF TASCTSDLCQ SMGDVATWCR ALAEYARACA 400
QAGRPLQGWR TQLRQCTVHC KEKAFTYNEC IACCPASCHP RASCVDSEIA 450
CVDGCYCPNG LIFEDGGCVA PAECPCEFHG TLYPPGSVVK EDCNTCTCTS 500
GKWECSTAVC PAECSVTGDI HFTTFDGRRY TFPATCQYIL AKSRSSGTFT 550
VTLQNAPCGL NQDGACVQSV SVILHQDPRR QVTLTQAGDV LLFDQYKIIP 600
PYTDDAFEIR RLSSVFLRVR TNVGVRVLYD REGLRLYLQV DQRWVEDTVG 650
LCGTFNGNTQ DDFLSPVGVP ESTPQLFGNS WKTLSACSPL VSGSPLDPCD 700
VHLQAASYSV QACSVLTGEM FAPCSAFLSP VPYFEQCRRD ACRCGQPCLC 750
ATLAHYAHLC RRHGLPVDFR ARLPACALSC EASKEYSPCV APCGRTCQDL 800
ASPEACGVDG GDDLSRDECV EGCACPPDTY LDTQADLCVP RNQCSCHFQG 850
VDYPPGDSDI PSLGHCHCKD GVMSCDSRAP AAACPAGQVF VNCSDLHTDL 900
ELSRERTCEQ QLLNLSVSAR GPCLSGCACP QGLLRHGDAC FLPEECPCTW 950
KGKEYFPGDQ VMSPCHTCVC QRGSFQCTLH PCASTCTAYG DRHYRTFDGL 1000
PFDFVGACKV HLVKSTSDVS FSVIVENVNC YSSGMICRKF ISINVGNSLI 1050
VFDDDSGNPS PESFLDDKQE VHTWRVGFFT LVHFPQEHIT LLWDQRTTVH 1100
VQAGPQWQGQ LAGLCGNFDL KTINEMRTPE NLELTNPQEF GSSWAAVECP 1150
DTLDPRDMCV LNPLREPFAK KECSILLSEV FEICHPVVDV TWFYSNCLTD 1200
TCGCSQGGDC ECFCASVSAY AHQCCQHGVA VDWRTPRLCP YDCDFFNKVL 1250
GKGPYQLSSL AAGGALVGMK AVGDDIVLVR TEDVAPADIV SFLLTAALYK 1300
AKAHDPDVVS LEAADRPNFF LHVTANGSLE LAKWQGRDTF QQHASFLLHR 1350
GTRQAGLVAL ESLAKPSSFL YVSGAVLALR LYEHTEVFRR GTLFRLLDAK 1400
PSGAAYPICE WRYDACASPC FQTCRDPRAA SCRDVPRVEG CVPVCPTPQV 1450
LDEVTQRCVY LEDCVEPAVW VPTEALGNET LPPSQGLPTP SDEEPQLSQE 1500
SPRTPTHRPA LTPAAPLTTA LNPPVTATEE PVVSPGPTQT TLQQPLELTA 1550
SQLPAGPTES PASKGVTASL LAIPHTPESS SLPVALQTPT PGMVSGAMET 1600
TRVTVIFAGS PNITVSSRSP PAPRFPLMTK AVTVRGHGSL PVRTTPPQPS 1650
LTASPSSRPV ASPGAISRSP TSSGSHKAVL TPAVTKVISR TGVPQPTQAQ 1700
SASSPSTPLT VAGTAAEQVP VSPLATRSLE IVLSTEKGEA GHSQPMGSPA 1750
SPQPHPLPSA PPRPAQHTTM ATRSPALPPE TPAAASLSTA TDGLAATPFM 1800
SLESTRPSQL LSGLPPDTSL PLAKVGTSAP VATPGPKASV ITTPLQPQAT 1850
TLPAQTLSPV LPFTPAAMTQ AHPPTHIAPP AAGTAPGLLL GATLPTSGVL 1900
PVAEGTASMV SVVPRKSTTG KVAILSKQVS LPTSMYGSAE GGPTELTPAT 1950
SHPLTPLVAE PEGAQAGTAL PVPTSYALSR VSARTAPQDS MLVLLPQLAE 2000
AHGTSAGPHL AAEPVDEATT EPSGRSAPAL SIVEGLAEAL ATTTEANTST 2050
TCVPIAEQDC VRHICLEGQL IRVNQSQHCP QGAAPPRCGI LGLAVRVGGD 2100
RCCPLWECAC RCSIFPDLSF VTFDGSHVAL FKEAIYILSQ SPDEMLTVHV 2150
LDCKSANLGH LNWPPFCLVM LNMTHLAHQV TIDRFNRKVT VDLQPVWPPV 2200
SRYGFRIEDT GHMYMILTPS DIQIQWLHSS GLMIVEASKT SKAQGHGLCG 2250
ICDGDAANDL TLKDGSVVGG AEDPAPFLDS WQVPSSLTSV GQTRFRPDSC 2300
ATTDCSPCLR MVSNRTFSAC HRFVPPESFC ELWIRDTKYV QQPCVALTVY 2350
VAMCHKFHVC IEWRRSDYCP FLCSSDSTYQ ACVTACEPPK TCQDGILGPL 2400
DPEHCQVLGE GCVCSEGTIL HRRHSALCIP EAKCACTDSM GVPRALGETW 2450
NSSLSGCCQH QCQAPDTIVP VDLGCPSPRP ESCLRFGEVA LLLPTKDPCC 2500
LGTVCVCNQT LCEGLAPTCR PGHRLLTHFQ EDSCCPSYSC ECDPDLCEAE 2550
LVPSCRQDQI LITGRLGDSC CTSYFCACGD CPDSIPECQE GEALTVHRNT 2600
TELCCPLYQC VCENFRCPQV QCGLGTALVE VWSPDRCCPY KSCECDCDTI 2650
PVPRCHLWEK SQLDEEFMHS VENVCGCAKY ECVKAPVCLS RELGVMQPGQ 2700
TVVELSADGV CHTSRCTTVL DPLTNFYQIN TTSVLCDIHC EANQEYEHPR 2750
DLAACCGSCR NVSCLFTFPN GTTSLFLPGA SWIADCARHH CSSTPLGAVL 2800
VRSPISCPPL NETECAKVGG SVVPSLEGCC RTCKEDGRSC KKVTIRMTIR 2850
KNECRSSTPV NLVSCDGRCP SASIYNYNIN TYARFCKCCR EVGLQRRSVQ 2900
LFCATNATWV PYTVQEPTDC ACQWS 2925

Note: No experimental confirmation available.

Length:2,925
Mass (Da):314,794
Last modified:November 25, 2008 - v3
Checksum:iD3555CAA3D9AE5FA
GO
Isoform 2 (identifier: Q6ZRI0-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-985: Missing.
     986-1014: CTAYGDRHYRTFDGLPFDFVGACKVHLVK → MFPARGVPLHLEGEGVFPWGPGDVSLPYL
     1240-1249: PYDCDFFNKV → L
     2434-2575: Missing.
     2644-2644: E → G
     2645-2925: Missing.

Note: No experimental confirmation available.

Show »
Length:1,508
Mass (Da):160,321
Checksum:iCEFB9E9A41CE0FF2
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti375 – 3751T → S.
Corresponds to variant rs7130190 [ dbSNP | Ensembl ].
VAR_037406
Natural varianti391 – 3911A → D.
Corresponds to variant rs61611064 [ dbSNP | Ensembl ].
VAR_061161
Natural varianti659 – 6591T → M.
Corresponds to variant rs7112749 [ dbSNP | Ensembl ].
VAR_037407
Natural varianti692 – 6921S → P.
Corresponds to variant rs7106548 [ dbSNP | Ensembl ].
VAR_037408
Natural varianti919 – 9191A → T.
Corresponds to variant rs2355466 [ dbSNP | Ensembl ].
VAR_037409
Natural varianti1075 – 10751R → Q.
Corresponds to variant rs11024333 [ dbSNP | Ensembl ].
VAR_037410
Natural varianti1112 – 11121A → V.
Corresponds to variant rs7936324 [ dbSNP | Ensembl ].
VAR_037411
Natural varianti1129 – 11291P → L.
Corresponds to variant rs7936354 [ dbSNP | Ensembl ].
VAR_037412
Natural varianti1399 – 13991A → G.
Corresponds to variant rs4491195 [ dbSNP | Ensembl ].
VAR_037413
Natural varianti1646 – 16461P → L.
Corresponds to variant rs2041028 [ dbSNP | Ensembl ].
VAR_037414
Natural varianti1832 – 18321A → V.
Corresponds to variant rs1003490 [ dbSNP | Ensembl ].
VAR_037415
Natural varianti1947 – 19471T → M.
Corresponds to variant rs7111528 [ dbSNP | Ensembl ].
VAR_037416
Natural varianti2006 – 20061A → V.
Corresponds to variant rs11024341 [ dbSNP | Ensembl ].
VAR_047262
Natural varianti2116 – 21161P → L in DFNB18B. 1 Publication
VAR_069250
Natural varianti2750 – 27501R → Q.
Corresponds to variant rs12422210 [ dbSNP | Ensembl ].
VAR_037417
Natural varianti2909 – 29091W → S.
Corresponds to variant rs11024357 [ dbSNP | Ensembl ].
VAR_037418

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 985985Missing in isoform 2. VSP_029709Add
BLAST
Alternative sequencei986 – 101429CTAYG…VHLVK → MFPARGVPLHLEGEGVFPWG PGDVSLPYL in isoform 2. VSP_029710Add
BLAST
Alternative sequencei1240 – 124910PYDCDFFNKV → L in isoform 2. VSP_029711
Alternative sequencei2434 – 2575142Missing in isoform 2. VSP_029712Add
BLAST
Alternative sequencei2644 – 26441E → G in isoform 2. VSP_029713
Alternative sequencei2645 – 2925281Missing in isoform 2. VSP_029714Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1375 – 13751A → P in BAC87330. 1 Publication
Sequence conflicti2121 – 21211V → A in BAC87330. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK128214 mRNA. Translation: BAC87330.1.
AC124799 Genomic DNA. No translation available.
CCDSiCCDS59225.1. [Q6ZRI0-1]
RefSeqiNP_001264198.1. NM_001277269.1. [Q6ZRI0-1]
UniGeneiHs.688380.

Genome annotation databases

EnsembliENST00000342528; ENSP00000341666; ENSG00000188162. [Q6ZRI0-2]
ENST00000399391; ENSP00000382323; ENSG00000188162. [Q6ZRI0-1]
GeneIDi340990.
KEGGihsa:340990.
UCSCiuc001mnh.1. human. [Q6ZRI0-2]
uc031pzc.1. human. [Q6ZRI0-1]

Polymorphism databases

DMDMi215274227.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK128214 mRNA. Translation: BAC87330.1 .
AC124799 Genomic DNA. No translation available.
CCDSi CCDS59225.1. [Q6ZRI0-1 ]
RefSeqi NP_001264198.1. NM_001277269.1. [Q6ZRI0-1 ]
UniGenei Hs.688380.

3D structure databases

ProteinModelPortali Q6ZRI0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 131110. 1 interaction.
STRINGi 9606.ENSP00000382323.

PTM databases

PhosphoSitei Q6ZRI0.

Polymorphism databases

DMDMi 215274227.

Proteomic databases

PaxDbi Q6ZRI0.
PRIDEi Q6ZRI0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000342528 ; ENSP00000341666 ; ENSG00000188162 . [Q6ZRI0-2 ]
ENST00000399391 ; ENSP00000382323 ; ENSG00000188162 . [Q6ZRI0-1 ]
GeneIDi 340990.
KEGGi hsa:340990.
UCSCi uc001mnh.1. human. [Q6ZRI0-2 ]
uc031pzc.1. human. [Q6ZRI0-1 ]

Organism-specific databases

CTDi 340990.
GeneCardsi GC11P017530.
HGNCi HGNC:8516. OTOG.
MIMi 604487. gene.
614945. phenotype.
neXtProti NX_Q6ZRI0.
Orphaneti 90636. Autosomal recessive nonsyndromic sensorineural deafness type DFNB.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG12793.
HOVERGENi HBG108222.
InParanoidi Q6ZRI0.
OMAi PYFEQCR.
PhylomeDBi Q6ZRI0.
TreeFami TF300299.

Miscellaneous databases

GenomeRNAii 340990.
NextBioi 98054.
PROi Q6ZRI0.
SOURCEi Search...

Gene expression databases

Bgeei Q6ZRI0.
CleanExi HS_OTOG.
Genevestigatori Q6ZRI0.

Family and domain databases

InterProi IPR007934. AbfB.
IPR006207. Cys_knot_C.
IPR000742. EG-like_dom.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view ]
Pfami PF05270. AbfB. 1 hit.
PF08742. C8. 4 hits.
PF01826. TIL. 1 hit.
PF00094. VWD. 4 hits.
[Graphical view ]
SMARTi SM00832. C8. 4 hits.
SM00041. CT. 1 hit.
SM00214. VWC. 2 hits.
SM00216. VWD. 4 hits.
[Graphical view ]
SUPFAMi SSF110221. SSF110221. 1 hit.
SSF57567. SSF57567. 4 hits.
PROSITEi PS01225. CTCK_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS51233. VWFD. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Testis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: VARIANT DFNB18B LEU-2116.

Entry informationi

Entry nameiOTOG_HUMAN
AccessioniPrimary (citable) accession number: Q6ZRI0
Secondary accession number(s): A8MTX6, A8MUJ0, B7WPC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: November 25, 2008
Last modified: July 9, 2014
This is version 87 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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