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Q6ZQV5

- ZN788_HUMAN

UniProt

Q6ZQV5 - ZN788_HUMAN

Protein

Zinc finger protein 788

Gene

ZNF788

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 2 (10 Jul 2007)
      Previous versions | rss
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    Functioni

    May be involved in transcriptional regulation.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri56 – 7823C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri112 – 13423C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri140 – 16223C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri168 – 19023C2H2-type 4PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri196 – 21823C2H2-type 5PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri224 – 24623C2H2-type 6PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri252 – 27423C2H2-type 7PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri280 – 30223C2H2-type 8PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri308 – 33023C2H2-type 9PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri390 – 41223C2H2-type 10PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri418 – 44023C2H2-type 11; degeneratePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri446 – 46823C2H2-type 12PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri474 – 49623C2H2-type 13PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri502 – 52423C2H2-type 14PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri530 – 55223C2H2-type 15; degeneratePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri558 – 58023C2H2-type 16PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri586 – 60823C2H2-type 17; degeneratePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Zinc finger protein 788
    Gene namesi
    Name:ZNF788
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Unplaced

    Organism-specific databases

    HGNCiHGNC:33112. ZNF788.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 615615Zinc finger protein 788PRO_0000293696Add
    BLAST

    Proteomic databases

    PaxDbiQ6ZQV5.
    PRIDEiQ6ZQV5.

    PTM databases

    PhosphoSiteiQ6ZQV5.

    Expressioni

    Gene expression databases

    CleanExiHS_ZNF788.
    GenevestigatoriQ6ZQV5.

    Organism-specific databases

    HPAiHPA031128.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6ZQV5.
    SMRiQ6ZQV5. Positions 52-615.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 17 C2H2-type zinc fingers.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri56 – 7823C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri112 – 13423C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri140 – 16223C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri168 – 19023C2H2-type 4PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri196 – 21823C2H2-type 5PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri224 – 24623C2H2-type 6PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri252 – 27423C2H2-type 7PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri280 – 30223C2H2-type 8PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri308 – 33023C2H2-type 9PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri390 – 41223C2H2-type 10PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri418 – 44023C2H2-type 11; degeneratePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri446 – 46823C2H2-type 12PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri474 – 49623C2H2-type 13PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri502 – 52423C2H2-type 14PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri530 – 55223C2H2-type 15; degeneratePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri558 – 58023C2H2-type 16PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri586 – 60823C2H2-type 17; degeneratePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG316972.
    HOGENOMiHOG000234617.
    HOVERGENiHBG018163.
    InParanoidiQ6ZQV5.
    OMAiQKANDIA.
    PhylomeDBiQ6ZQV5.

    Family and domain databases

    Gene3Di3.30.160.60. 18 hits.
    InterProiIPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00096. zf-C2H2. 2 hits.
    [Graphical view]
    SMARTiSM00355. ZnF_C2H2. 16 hits.
    [Graphical view]
    PROSITEiPS00028. ZINC_FINGER_C2H2_1. 13 hits.
    PS50157. ZINC_FINGER_C2H2_2. 16 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6ZQV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNVRILRRHL VFPFIFIVIK ELTLEGTPMN VNNLENPLDA PQNFKCMQGL    50
    SVEKPYKCKK CEKAFNNLSS FQIHERMHRG GKYHACKGSG NTYRFSGFYH 100
    RHKMPHAGGK FYGCKKCGKA FISFCAFRYH QRTHTKEKPY ACKQCGKAYI 150
    SYTSFQYHQL NHTGAKCYEC KQCGKGFDLP NSIRYHEMTH TGEKPHECKQ 200
    CGKTFRCASS LRIHGRTHTG EKPYECKQCG KVSRYWSGLQ VHEVTHIGKK 250
    LYECKECGKS YYSSGSFLNH KRIHTREKSY ECKECGKAFG NPISFQKHEG 300
    SHRKWKPYEC KECGKVFSFS SSLRRHERTH TEKLCECKQH GKGFFHRSCP 350
    RHMKIDTGEI LHKRKIRGKV FHSPSSFQTC ERSHTREKRY KCKQCGKPFI 400
    YFNAFQRHQR SHTGENPYEC KQCGKACISS TAFQCRELSH TGAKRYKCKQ 450
    CGKGFNLPSS IRYHEMTHTG EKPYECKQCG RAFRSASHLR THERTHIGEK 500
    PYECKQCGKV YRYWSGLRIH GLTHIGKKPY EFNDRGKSFY SSNFFLNHKR 550
    VHTRVKTYEC KECGKAFDNP TSFQKHEGSH RKGKSYECKE CGKVFSFSRS 600
    FRRYERAHTG EKPCE 615
    Length:615
    Mass (Da):71,992
    Last modified:July 10, 2007 - v2
    Checksum:iD82640F0060AE848
    GO

    Sequence cautioni

    The sequence BAC87366.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti7 – 71R → G in BAC87578. (PubMed:14702039)Curated
    Sequence conflicti167 – 1671C → R in BAC87366. (PubMed:14702039)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK128282 mRNA. Translation: BAC87366.1. Different initiation.
    AK128700 mRNA. Translation: BAC87578.1.
    UniGeneiHs.127473.

    Genome annotation databases

    UCSCiuc002mtd.3. human.

    Polymorphism databases

    DMDMi152112418.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK128282 mRNA. Translation: BAC87366.1 . Different initiation.
    AK128700 mRNA. Translation: BAC87578.1 .
    UniGenei Hs.127473.

    3D structure databases

    ProteinModelPortali Q6ZQV5.
    SMRi Q6ZQV5. Positions 52-615.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q6ZQV5.

    Polymorphism databases

    DMDMi 152112418.

    Proteomic databases

    PaxDbi Q6ZQV5.
    PRIDEi Q6ZQV5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc002mtd.3. human.

    Organism-specific databases

    GeneCardsi GC19P012203.
    GC19P012204.
    HGNCi HGNC:33112. ZNF788.
    HPAi HPA031128.
    neXtProti NX_Q6ZQV5.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG316972.
    HOGENOMi HOG000234617.
    HOVERGENi HBG018163.
    InParanoidi Q6ZQV5.
    OMAi QKANDIA.
    PhylomeDBi Q6ZQV5.

    Miscellaneous databases

    ChiTaRSi ZNF788. human.
    PROi Q6ZQV5.

    Gene expression databases

    CleanExi HS_ZNF788.
    Genevestigatori Q6ZQV5.

    Family and domain databases

    Gene3Di 3.30.160.60. 18 hits.
    InterProi IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00096. zf-C2H2. 2 hits.
    [Graphical view ]
    SMARTi SM00355. ZnF_C2H2. 16 hits.
    [Graphical view ]
    PROSITEi PS00028. ZINC_FINGER_C2H2_1. 13 hits.
    PS50157. ZINC_FINGER_C2H2_2. 16 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Thymus and Uterus.

    Entry informationi

    Entry nameiZN788_HUMAN
    AccessioniPrimary (citable) accession number: Q6ZQV5
    Secondary accession number(s): Q6ZRE4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: July 10, 2007
    Last modified: October 1, 2014
    This is version 88 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3