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Q6ZQV5 (ZN788_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger protein 788
Gene names
Name:ZNF788
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length615 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in transcriptional regulation.

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Contains 17 C2H2-type zinc fingers.

Sequence caution

The sequence BAC87366.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainRepeat
Zinc-finger
   LigandDNA-binding
Metal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 615615Zinc finger protein 788
PRO_0000293696

Regions

Zinc finger56 – 7823C2H2-type 1
Zinc finger112 – 13423C2H2-type 2
Zinc finger140 – 16223C2H2-type 3
Zinc finger168 – 19023C2H2-type 4
Zinc finger196 – 21823C2H2-type 5
Zinc finger224 – 24623C2H2-type 6
Zinc finger252 – 27423C2H2-type 7
Zinc finger280 – 30223C2H2-type 8
Zinc finger308 – 33023C2H2-type 9
Zinc finger390 – 41223C2H2-type 10
Zinc finger418 – 44023C2H2-type 11; degenerate
Zinc finger446 – 46823C2H2-type 12
Zinc finger474 – 49623C2H2-type 13
Zinc finger502 – 52423C2H2-type 14
Zinc finger530 – 55223C2H2-type 15; degenerate
Zinc finger558 – 58023C2H2-type 16
Zinc finger586 – 60823C2H2-type 17; degenerate

Experimental info

Sequence conflict71R → G in BAC87578. Ref.1
Sequence conflict1671C → R in BAC87366. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q6ZQV5 [UniParc].

Last modified July 10, 2007. Version 2.
Checksum: D82640F0060AE848

FASTA61571,992
        10         20         30         40         50         60 
MNVRILRRHL VFPFIFIVIK ELTLEGTPMN VNNLENPLDA PQNFKCMQGL SVEKPYKCKK 

        70         80         90        100        110        120 
CEKAFNNLSS FQIHERMHRG GKYHACKGSG NTYRFSGFYH RHKMPHAGGK FYGCKKCGKA 

       130        140        150        160        170        180 
FISFCAFRYH QRTHTKEKPY ACKQCGKAYI SYTSFQYHQL NHTGAKCYEC KQCGKGFDLP 

       190        200        210        220        230        240 
NSIRYHEMTH TGEKPHECKQ CGKTFRCASS LRIHGRTHTG EKPYECKQCG KVSRYWSGLQ 

       250        260        270        280        290        300 
VHEVTHIGKK LYECKECGKS YYSSGSFLNH KRIHTREKSY ECKECGKAFG NPISFQKHEG 

       310        320        330        340        350        360 
SHRKWKPYEC KECGKVFSFS SSLRRHERTH TEKLCECKQH GKGFFHRSCP RHMKIDTGEI 

       370        380        390        400        410        420 
LHKRKIRGKV FHSPSSFQTC ERSHTREKRY KCKQCGKPFI YFNAFQRHQR SHTGENPYEC 

       430        440        450        460        470        480 
KQCGKACISS TAFQCRELSH TGAKRYKCKQ CGKGFNLPSS IRYHEMTHTG EKPYECKQCG 

       490        500        510        520        530        540 
RAFRSASHLR THERTHIGEK PYECKQCGKV YRYWSGLRIH GLTHIGKKPY EFNDRGKSFY 

       550        560        570        580        590        600 
SSNFFLNHKR VHTRVKTYEC KECGKAFDNP TSFQKHEGSH RKGKSYECKE CGKVFSFSRS 

       610 
FRRYERAHTG EKPCE 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Thymus and Uterus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK128282 mRNA. Translation: BAC87366.1. Different initiation.
AK128700 mRNA. Translation: BAC87578.1.
UniGeneHs.127473.

3D structure databases

ProteinModelPortalQ6ZQV5.
SMRQ6ZQV5. Positions 52-615.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ6ZQV5.

Polymorphism databases

DMDM152112418.

Proteomic databases

PaxDbQ6ZQV5.
PRIDEQ6ZQV5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc002mtd.3. human.

Organism-specific databases

GeneCardsGC19P012203.
GC19P012204.
HGNCHGNC:33112. ZNF788.
HPAHPA031128.
neXtProtNX_Q6ZQV5.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG316972.
HOGENOMHOG000234617.
HOVERGENHBG018163.
InParanoidQ6ZQV5.
OMAQKANDIA.
PhylomeDBQ6ZQV5.

Gene expression databases

CleanExHS_ZNF788.
GenevestigatorQ6ZQV5.

Family and domain databases

Gene3D3.30.160.60. 18 hits.
InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 16 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 16 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSZNF788. human.
PROQ6ZQV5.

Entry information

Entry nameZN788_HUMAN
AccessionPrimary (citable) accession number: Q6ZQV5
Secondary accession number(s): Q6ZRE4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: May 14, 2014
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM