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Q6ZQV5

- ZN788_HUMAN

UniProt

Q6ZQV5 - ZN788_HUMAN

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Protein

Zinc finger protein 788

Gene

ZNF788

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri56 – 7823C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri112 – 13423C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri140 – 16223C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri168 – 19023C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri196 – 21823C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri224 – 24623C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri252 – 27423C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri280 – 30223C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri308 – 33023C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri390 – 41223C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri418 – 44023C2H2-type 11; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri446 – 46823C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri474 – 49623C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri502 – 52423C2H2-type 14PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri530 – 55223C2H2-type 15; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri558 – 58023C2H2-type 16PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri586 – 60823C2H2-type 17; degeneratePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 788
Gene namesi
Name:ZNF788
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:33112. ZNF788.

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 615615Zinc finger protein 788PRO_0000293696Add
BLAST

Proteomic databases

PaxDbiQ6ZQV5.
PRIDEiQ6ZQV5.

PTM databases

PhosphoSiteiQ6ZQV5.

Expressioni

Gene expression databases

CleanExiHS_ZNF788.
GenevestigatoriQ6ZQV5.

Organism-specific databases

HPAiHPA031128.

Structurei

3D structure databases

ProteinModelPortaliQ6ZQV5.
SMRiQ6ZQV5. Positions 52-615.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 17 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri56 – 7823C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri112 – 13423C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri140 – 16223C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri168 – 19023C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri196 – 21823C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri224 – 24623C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri252 – 27423C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri280 – 30223C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri308 – 33023C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri390 – 41223C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri418 – 44023C2H2-type 11; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri446 – 46823C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri474 – 49623C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri502 – 52423C2H2-type 14PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri530 – 55223C2H2-type 15; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri558 – 58023C2H2-type 16PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri586 – 60823C2H2-type 17; degeneratePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG316972.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ6ZQV5.
OMAiQKANDIA.
PhylomeDBiQ6ZQV5.

Family and domain databases

Gene3Di3.30.160.60. 18 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 16 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 16 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZQV5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNVRILRRHL VFPFIFIVIK ELTLEGTPMN VNNLENPLDA PQNFKCMQGL
60 70 80 90 100
SVEKPYKCKK CEKAFNNLSS FQIHERMHRG GKYHACKGSG NTYRFSGFYH
110 120 130 140 150
RHKMPHAGGK FYGCKKCGKA FISFCAFRYH QRTHTKEKPY ACKQCGKAYI
160 170 180 190 200
SYTSFQYHQL NHTGAKCYEC KQCGKGFDLP NSIRYHEMTH TGEKPHECKQ
210 220 230 240 250
CGKTFRCASS LRIHGRTHTG EKPYECKQCG KVSRYWSGLQ VHEVTHIGKK
260 270 280 290 300
LYECKECGKS YYSSGSFLNH KRIHTREKSY ECKECGKAFG NPISFQKHEG
310 320 330 340 350
SHRKWKPYEC KECGKVFSFS SSLRRHERTH TEKLCECKQH GKGFFHRSCP
360 370 380 390 400
RHMKIDTGEI LHKRKIRGKV FHSPSSFQTC ERSHTREKRY KCKQCGKPFI
410 420 430 440 450
YFNAFQRHQR SHTGENPYEC KQCGKACISS TAFQCRELSH TGAKRYKCKQ
460 470 480 490 500
CGKGFNLPSS IRYHEMTHTG EKPYECKQCG RAFRSASHLR THERTHIGEK
510 520 530 540 550
PYECKQCGKV YRYWSGLRIH GLTHIGKKPY EFNDRGKSFY SSNFFLNHKR
560 570 580 590 600
VHTRVKTYEC KECGKAFDNP TSFQKHEGSH RKGKSYECKE CGKVFSFSRS
610
FRRYERAHTG EKPCE
Length:615
Mass (Da):71,992
Last modified:July 10, 2007 - v2
Checksum:iD82640F0060AE848
GO

Sequence cautioni

The sequence BAC87366.1 differs from that shown. Reason: Erroneous initiation.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti7 – 71R → G in BAC87578. (PubMed:14702039)Curated
Sequence conflicti167 – 1671C → R in BAC87366. (PubMed:14702039)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK128282 mRNA. Translation: BAC87366.1. Different initiation.
AK128700 mRNA. Translation: BAC87578.1.
UniGeneiHs.127473.

Genome annotation databases

UCSCiuc002mtd.3. human.

Polymorphism databases

DMDMi152112418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK128282 mRNA. Translation: BAC87366.1 . Different initiation.
AK128700 mRNA. Translation: BAC87578.1 .
UniGenei Hs.127473.

3D structure databases

ProteinModelPortali Q6ZQV5.
SMRi Q6ZQV5. Positions 52-615.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q6ZQV5.

Polymorphism databases

DMDMi 152112418.

Proteomic databases

PaxDbi Q6ZQV5.
PRIDEi Q6ZQV5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc002mtd.3. human.

Organism-specific databases

GeneCardsi GC19P012203.
GC19P012204.
HGNCi HGNC:33112. ZNF788.
HPAi HPA031128.
neXtProti NX_Q6ZQV5.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG316972.
HOGENOMi HOG000234617.
HOVERGENi HBG018163.
InParanoidi Q6ZQV5.
OMAi QKANDIA.
PhylomeDBi Q6ZQV5.

Miscellaneous databases

ChiTaRSi ZNF788. human.
PROi Q6ZQV5.

Gene expression databases

CleanExi HS_ZNF788.
Genevestigatori Q6ZQV5.

Family and domain databases

Gene3Di 3.30.160.60. 18 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF00096. zf-C2H2. 2 hits.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 16 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 16 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Thymus and Uterus.

Entry informationi

Entry nameiZN788_HUMAN
AccessioniPrimary (citable) accession number: Q6ZQV5
Secondary accession number(s): Q6ZRE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: October 29, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3