Q6ZQQ6 (WDR87_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
WD repeat-containing protein 87

Alternative name(s):
Testis development protein NYD-SP11

Gene names

Name:

WDR87

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	2873 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities	Contains 7 WD repeats.
Sequence caution	The sequence AAK20167.2 differs from that shown. Reason: Erroneous termination at position 825. Translated as Trp. The sequence AAK20167.2 differs from that shown. Reason: Frameshift at positions 126, 820, 1129 and 1140.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat WD repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q6ZQQ6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q6ZQQ6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     42-42: S → SQALFKESRYPQNMPCVCYYFSDAHFFASLSWVTSNTKEI

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 2873	2873	WD repeat-containing protein 87		PRO_0000314821
Regions
	Repeat	108 – 146	39	WD 1
	Repeat	199 – 239	41	WD 2
	Repeat	242 – 283	42	WD 3
	Repeat	368 – 407	40	WD 4
	Repeat	415 – 460	46	WD 5
	Repeat	516 – 553	38	WD 6
	Repeat	565 – 604	40	WD 7
	Compositional bias	1419 – 2347	929	Glu-rich
Natural variations
	Alternative sequence	42	1	S → SQALFKESRYPQNMPCVCYY FSDAHFFASLSWVTSNTKEI in isoform 2.		VSP_030380
	Natural variant	496	1	H → Y. Corresponds to variant rs12104280 [ dbSNP | Ensembl ].		VAR_057638
	Natural variant	1583	1	R → Q. Corresponds to variant rs6508750 [ dbSNP | Ensembl ].		VAR_057639
	Natural variant	1885	1	N → K. Corresponds to variant rs10422056 [ dbSNP | Ensembl ].		VAR_057640
	Natural variant	2570	1	H → L. Corresponds to variant rs10408510 [ dbSNP | Ensembl ].		VAR_057641
Experimental info
	Sequence conflict	135	1	T → S in AAK20167. Ref.3
	Sequence conflict	177	1	T → A in BAC87627. Ref.2
	Sequence conflict	226	1	I → T in AAK20167. Ref.3
	Sequence conflict	529	1	K → Q in AAK20167. Ref.3
	Sequence conflict	602	1	G → A in BAC87627. Ref.2
	Sequence conflict	602	1	G → A in AAK20167. Ref.3
	Sequence conflict	817 – 818	2	DR → NS in AAK20167. Ref.3
	Sequence conflict	821	1	E → G in AAK20167. Ref.3
	Sequence conflict	939	1	E → G in AAK20167. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 18, 2010. Version 3. Checksum: E4BC3A63C503BAB4	FASTA	2,873	333,185
	10 20 30 40 50 60 MSSPRLIPLW KDLKLLLNDT INKSKQPSED PKNCLIVLSD RSQAVAWMKS KTEDMVEKRT 70 80 90 100 110 120 FSMTERLPPI QSMVHAGSFH ILVVYCGDLI LRLFGDHFRA FKPLGKVPCR FNISCLCYDP 130 140 150 160 170 180 EMKMLLSGIL GAVVTWVIEL GGTGLQIAHM VSMPGDELVQ DIVLNGPSGS LLALCETVVR 190 200 210 220 230 240 VLMHQGKGQL GEVKRFTSTS SGSSITCCFT CFDQGFLYAG NQAGEIQVWS LQQGHPLHSF 250 260 270 280 290 300 QAHQSGVICI RSRPEAHTLL TAGSDSLIKE WNLTSGSLLR RLELGEELYR LQFIDSITFF 310 320 330 340 350 360 CQTAHSFSLH RLPCFYSLFN VCGSAPQQLR RVCCGNNWFR ILCTTEDGLL RFVSPVTGDL 370 380 390 400 410 420 LVITWPFSIL DQAVDWAYDP GKEELFVATG SSEVLVFDTT RCPCPAKYLL GTSPNSQDFV 430 440 450 460 470 480 QCLAYGHFNL GRGLEGLIFS GHQSGVIRVL SQHSCARLEK FMHFGAVLAL STLSGGIFGG 490 500 510 520 530 540 QGNSLLCSYG MDDYVHLSEA VLDGVKVQLR PLASILSSCH LTHLILLPKS VGAITETNCL 550 560 570 580 590 600 RLWKFHDFLS SGSQNGLKFI ETLPLHLCAI TSFDVCLSLS LFVTGSADGS VRIWDFHGRL 610 620 630 640 650 660 IGILDSSLHF GPVCFANDRG DLLVTFNQSL YLVSCLKLLP PALLTRLSFM SISDEVLEVP 670 680 690 700 710 720 KPFIPSFFFS FETMFVPKYI YPGQAQQKLV GLEKLVNNRA IAFDHSVPHV IEEDEEGSPV 730 740 750 760 770 780 LLRSSMHYSL QDMEDWMQVS KRYQCHYVLP PQLQLTSWDG LNPYQILRYY FGHGREWLFA 790 800 810 820 830 840 PDCYIPNSVI RARLWPEGTP IYLQCNLHAP QRELEWDRSQ EFFFWHSRVR AISNTEYPKN 850 860 870 880 890 900 KEEDEHFLEM RLSKDVTYSV LTDGANRSWL GRKMSEITIN SMIETMLNIM VHASLLKYQC 910 920 930 940 950 960 CVGALGQIFA SYQVSPALRS ETARRLLNDT TNSNPLIREL AWEGLKRLGM ITHLFAMPLA 970 980 990 1000 1010 1020 QGLMDKDERV RIKTLSLMAE IGIHSRTSLL QLTQKQETFR EMQQQMIGEE PLDHLLGMRA 1030 1040 1050 1060 1070 1080 TDLQILSTQV EQRLNENLTL SHRDEKPAFS LDVSMPSELK SSLKPPTVSE ESEVAIKPSK 1090 1100 1110 1120 1130 1140 GQRRGQAGVK KHSQKWLRGL KKTKERDSKQ MSTEPGLLED ESGTEAAPIE MEEASVYSQW 1150 1160 1170 1180 1190 1200 SSSTSVIKLS KDVDSQEKDI SKDHIALTLK RLQKIRDKRD KKATAQKLKK KHKKKGKEAK 1210 1220 1230 1240 1250 1260 VINEETTPPV MEQPVTKKVK IQGRGASGIS GRRSTAGDGS SWRDDLCRLM ALRISGSQTK 1270 1280 1290 1300 1310 1320 MSENLNAELV TFAQEMLVDR HPSWELFQEI CPLLKKESKV LLEDLDWDVV PPEKKPIFIQ 1330 1340 1350 1360 1370 1380 EGAIREDMIQ GVTQEVIRHK EVMPREEEQA QKKARDMLGL EETQVILKKG KKVIFLEPGN 1390 1400 1410 1420 1430 1440 VTMGKEISKK EEKKTFQKSP KQGRKAVQKE RKVGKIKREM TKEERDMSEE VEEMATLEEK 1450 1460 1470 1480 1490 1500 VVKQEGKLVM IERTPSWQDW KKAWDEWKQV HGETRKSWKA WKEEWEKRLL QEEEKLHQAG 1510 1520 1530 1540 1550 1560 EKLSPEEEML QEDKKLKWEE WKQVWENMLS SKSKEQQYKD EEEVTLEEEV SREGEEKEQQ 1570 1580 1590 1600 1610 1620 VTEEQRHIQE EHKWARIHRK RARAEKKRAQ EERKLAQEEE KLAQEERQLA QEERKLAQAY 1630 1640 1650 1660 1670 1680 VKITQDDREM AQAEGKFAQK EETLAQRGEK LSQEAEKLAQ KRKKLAKKWE KVAREEEKLA 1690 1700 1710 1720 1730 1740 KKGGKLAEVK NILAQKVEEL PQREQNLDWQ EKELAQELEE LEWDMEELSW KEEELNQEEG 1750 1760 1770 1780 1790 1800 KLVEEKKKLA EEEEALAWQR EKLSEEETKL AQEEELLIQE KEKLAQHKEK MPEEEERLGR 1810 1820 1830 1840 1850 1860 KREQLIEKKM KLAQKRERWI NSMEELTKNK MILYQKKNLA QEKKNLAQEK EKLAQRKENL 1870 1880 1890 1900 1910 1920 LYNKERLTHS KKQLVQVKNK LGMFNKILAQ VEEKLTQEKE TVIKKKEKLA ETEKKLVQVE 1930 1940 1950 1960 1970 1980 DSLAKKQEKL AQEKMKLALE KAMVQGKKRL RGELDIAKEE KALNLEMKRL AEEKMRLVEG 1990 2000 2010 2020 2030 2040 KETLSKGETP ETSRQRKMTQ VEQELFERKL SLEEKILLHE DRILAMEESE IAKGKLEFTR 2050 2060 2070 2080 2090 2100 GQRIFVQGQR KLAKASRKLI KKRESLSKEP AKLNKILKAL QKLTRDERKL TQEEIKMTKM 2110 2120 2130 2140 2150 2160 KRALFVKERR LSIEQSKLDI KEWDFSEKRS ELTKDEKKLA RKQRKLANKM RRMINKEEKM 2170 2180 2190 2200 2210 2220 TEEESKLARK HSEVILDDEE EGGIEEEEVI PFLKRRWRKR KEAKRGDKPK EKFSSQVDEV 2230 2240 2250 2260 2270 2280 ESEEHFSEEM ESLLDELEKQ ESLSSEEEEE REEEEEREEE EVREEEEERK EEEEGEEKQV 2290 2300 2310 2320 2330 2340 EKEEEEKKKK KKEKKKEEVQ EKEEVFEEKE EIMSEEETES LSDEEEEEES CSLEEEVDRE 2350 2360 2370 2380 2390 2400 KEILKKEKQF KLQEQRRKSL RGRERVLSIL RGVPHGKGRA IRLGVLKSPL KKLMSTALEM 2410 2420 2430 2440 2450 2460 KEKTPVPVPE KQISWEDKKA TVVEIPRKFL GTMDKEREVM GKYEPIPPHV LGTVLESQAQ 2470 2480 2490 2500 2510 2520 DLKTPFMSHI LRRTVEAEEL QHKPLGAWWK WFLQHPPLMG QTEVQLPLSQ IPAKEQHADV 2530 2540 2550 2560 2570 2580 SLSDVEWIRH VLERMEAGEQ LSRDGFHRLC QLLKDLASKG NLEWLHLAKH EAIVYRHRQA 2590 2600 2610 2620 2630 2640 LESQDTRISS RQSMSPKYLK VIPPIKAKEK ESWPKPLAVP TQKSPLATKR IPDPRAKNWH 2650 2660 2670 2680 2690 2700 LLGEPYRSER AQQISIAHKE MEMQYFYPAT RDIFPSAHAS VEKQTLALMF QKDFWDFKDK 2710 2720 2730 2740 2750 2760 RRFPKLPKLE KKTQPISKKK EELPLWETFV ALYHVLRMLQ QRYPKDSTAW MEQFYQLMDL 2770 2780 2790 2800 2810 2820 YQLKSPRIQK LLQELLMREE PQPQEIIYEE ALKATELVPG ERLFCCLFCG SSHTPRSPQE 2830 2840 2850 2860 2870 FQGAVPLPWQ NCVRTILPVG IARYGILELA WKSLPEADLH LTKALTHTVA PTL
	Isoform 2 [UniParc]. Checksum: F92E39FC2179E241	FASTA	2,912	337,777
	10 20 30 40 50 60 MSSPRLIPLW KDLKLLLNDT INKSKQPSED PKNCLIVLSD RSQALFKESR YPQNMPCVCY 70 80 90 100 110 120 YFSDAHFFAS LSWVTSNTKE IQAVAWMKSK TEDMVEKRTF SMTERLPPIQ SMVHAGSFHI 130 140 150 160 170 180 LVVYCGDLIL RLFGDHFRAF KPLGKVPCRF NISCLCYDPE MKMLLSGILG AVVTWVIELG 190 200 210 220 230 240 GTGLQIAHMV SMPGDELVQD IVLNGPSGSL LALCETVVRV LMHQGKGQLG EVKRFTSTSS 250 260 270 280 290 300 GSSITCCFTC FDQGFLYAGN QAGEIQVWSL QQGHPLHSFQ AHQSGVICIR SRPEAHTLLT 310 320 330 340 350 360 AGSDSLIKEW NLTSGSLLRR LELGEELYRL QFIDSITFFC QTAHSFSLHR LPCFYSLFNV 370 380 390 400 410 420 CGSAPQQLRR VCCGNNWFRI LCTTEDGLLR FVSPVTGDLL VITWPFSILD QAVDWAYDPG 430 440 450 460 470 480 KEELFVATGS SEVLVFDTTR CPCPAKYLLG TSPNSQDFVQ CLAYGHFNLG RGLEGLIFSG 490 500 510 520 530 540 HQSGVIRVLS QHSCARLEKF MHFGAVLALS TLSGGIFGGQ GNSLLCSYGM DDYVHLSEAV 550 560 570 580 590 600 LDGVKVQLRP LASILSSCHL THLILLPKSV GAITETNCLR LWKFHDFLSS GSQNGLKFIE 610 620 630 640 650 660 TLPLHLCAIT SFDVCLSLSL FVTGSADGSV RIWDFHGRLI GILDSSLHFG PVCFANDRGD 670 680 690 700 710 720 LLVTFNQSLY LVSCLKLLPP ALLTRLSFMS ISDEVLEVPK PFIPSFFFSF ETMFVPKYIY 730 740 750 760 770 780 PGQAQQKLVG LEKLVNNRAI AFDHSVPHVI EEDEEGSPVL LRSSMHYSLQ DMEDWMQVSK 790 800 810 820 830 840 RYQCHYVLPP QLQLTSWDGL NPYQILRYYF GHGREWLFAP DCYIPNSVIR ARLWPEGTPI 850 860 870 880 890 900 YLQCNLHAPQ RELEWDRSQE FFFWHSRVRA ISNTEYPKNK EEDEHFLEMR LSKDVTYSVL 910 920 930 940 950 960 TDGANRSWLG RKMSEITINS MIETMLNIMV HASLLKYQCC VGALGQIFAS YQVSPALRSE 970 980 990 1000 1010 1020 TARRLLNDTT NSNPLIRELA WEGLKRLGMI THLFAMPLAQ GLMDKDERVR IKTLSLMAEI 1030 1040 1050 1060 1070 1080 GIHSRTSLLQ LTQKQETFRE MQQQMIGEEP LDHLLGMRAT DLQILSTQVE QRLNENLTLS 1090 1100 1110 1120 1130 1140 HRDEKPAFSL DVSMPSELKS SLKPPTVSEE SEVAIKPSKG QRRGQAGVKK HSQKWLRGLK 1150 1160 1170 1180 1190 1200 KTKERDSKQM STEPGLLEDE SGTEAAPIEM EEASVYSQWS SSTSVIKLSK DVDSQEKDIS 1210 1220 1230 1240 1250 1260 KDHIALTLKR LQKIRDKRDK KATAQKLKKK HKKKGKEAKV INEETTPPVM EQPVTKKVKI 1270 1280 1290 1300 1310 1320 QGRGASGISG RRSTAGDGSS WRDDLCRLMA LRISGSQTKM SENLNAELVT FAQEMLVDRH 1330 1340 1350 1360 1370 1380 PSWELFQEIC PLLKKESKVL LEDLDWDVVP PEKKPIFIQE GAIREDMIQG VTQEVIRHKE 1390 1400 1410 1420 1430 1440 VMPREEEQAQ KKARDMLGLE ETQVILKKGK KVIFLEPGNV TMGKEISKKE EKKTFQKSPK 1450 1460 1470 1480 1490 1500 QGRKAVQKER KVGKIKREMT KEERDMSEEV EEMATLEEKV VKQEGKLVMI ERTPSWQDWK 1510 1520 1530 1540 1550 1560 KAWDEWKQVH GETRKSWKAW KEEWEKRLLQ EEEKLHQAGE KLSPEEEMLQ EDKKLKWEEW 1570 1580 1590 1600 1610 1620 KQVWENMLSS KSKEQQYKDE EEVTLEEEVS REGEEKEQQV TEEQRHIQEE HKWARIHRKR 1630 1640 1650 1660 1670 1680 ARAEKKRAQE ERKLAQEEEK LAQEERQLAQ EERKLAQAYV KITQDDREMA QAEGKFAQKE 1690 1700 1710 1720 1730 1740 ETLAQRGEKL SQEAEKLAQK RKKLAKKWEK VAREEEKLAK KGGKLAEVKN ILAQKVEELP 1750 1760 1770 1780 1790 1800 QREQNLDWQE KELAQELEEL EWDMEELSWK EEELNQEEGK LVEEKKKLAE EEEALAWQRE 1810 1820 1830 1840 1850 1860 KLSEEETKLA QEEELLIQEK EKLAQHKEKM PEEEERLGRK REQLIEKKMK LAQKRERWIN 1870 1880 1890 1900 1910 1920 SMEELTKNKM ILYQKKNLAQ EKKNLAQEKE KLAQRKENLL YNKERLTHSK KQLVQVKNKL 1930 1940 1950 1960 1970 1980 GMFNKILAQV EEKLTQEKET VIKKKEKLAE TEKKLVQVED SLAKKQEKLA QEKMKLALEK 1990 2000 2010 2020 2030 2040 AMVQGKKRLR GELDIAKEEK ALNLEMKRLA EEKMRLVEGK ETLSKGETPE TSRQRKMTQV 2050 2060 2070 2080 2090 2100 EQELFERKLS LEEKILLHED RILAMEESEI AKGKLEFTRG QRIFVQGQRK LAKASRKLIK 2110 2120 2130 2140 2150 2160 KRESLSKEPA KLNKILKALQ KLTRDERKLT QEEIKMTKMK RALFVKERRL SIEQSKLDIK 2170 2180 2190 2200 2210 2220 EWDFSEKRSE LTKDEKKLAR KQRKLANKMR RMINKEEKMT EEESKLARKH SEVILDDEEE 2230 2240 2250 2260 2270 2280 GGIEEEEVIP FLKRRWRKRK EAKRGDKPKE KFSSQVDEVE SEEHFSEEME SLLDELEKQE 2290 2300 2310 2320 2330 2340 SLSSEEEEER EEEEEREEEE VREEEEERKE EEEGEEKQVE KEEEEKKKKK KEKKKEEVQE 2350 2360 2370 2380 2390 2400 KEEVFEEKEE IMSEEETESL SDEEEEEESC SLEEEVDREK EILKKEKQFK LQEQRRKSLR 2410 2420 2430 2440 2450 2460 GRERVLSILR GVPHGKGRAI RLGVLKSPLK KLMSTALEMK EKTPVPVPEK QISWEDKKAT 2470 2480 2490 2500 2510 2520 VVEIPRKFLG TMDKEREVMG KYEPIPPHVL GTVLESQAQD LKTPFMSHIL RRTVEAEELQ 2530 2540 2550 2560 2570 2580 HKPLGAWWKW FLQHPPLMGQ TEVQLPLSQI PAKEQHADVS LSDVEWIRHV LERMEAGEQL 2590 2600 2610 2620 2630 2640 SRDGFHRLCQ LLKDLASKGN LEWLHLAKHE AIVYRHRQAL ESQDTRISSR QSMSPKYLKV 2650 2660 2670 2680 2690 2700 IPPIKAKEKE SWPKPLAVPT QKSPLATKRI PDPRAKNWHL LGEPYRSERA QQISIAHKEM 2710 2720 2730 2740 2750 2760 EMQYFYPATR DIFPSAHASV EKQTLALMFQ KDFWDFKDKR RFPKLPKLEK KTQPISKKKE 2770 2780 2790 2800 2810 2820 ELPLWETFVA LYHVLRMLQQ RYPKDSTAWM EQFYQLMDLY QLKSPRIQKL LQELLMREEP 2830 2840 2850 2860 2870 2880 QPQEIIYEEA LKATELVPGE RLFCCLFCGS SHTPRSPQEF QGAVPLPWQN CVRTILPVGI 2890 2900 2910 ARYGILELAW KSLPEADLHL TKALTHTVAP TL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and biology of human chromosome 19." Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M. Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1350 (ISOFORM 1). Tissue: Testis.
[3]	"Cloning of new testis gene (NYD-SP11) related to testis development from human testis cDNA library." Sha J.H. Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1170 (ISOFORM 2). Tissue: Testis.
[4]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC016582 Genomic DNA. No translation available. AK128826 mRNA. Translation: BAC87627.1. AY026504 mRNA. Translation: AAK20167.2. Sequence problems.
IPI	IPI00397715. IPI00744524.
RefSeq	NP_114157.3. NM_031951.3.
UniGene	Hs.664194.
3D structure databases
ProteinModelPortal	Q6ZQQ6.
SMR	Q6ZQQ6. Positions 87-125, 213-274, 566-598.
ModBase	Search...
PTM databases
PhosphoSite	Q6ZQQ6.
Polymorphism databases
DMDM	296453080.
Proteomic databases
PaxDb	Q6ZQQ6.
PRIDE	Q6ZQQ6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000303868; ENSP00000368025; ENSG00000171804.
GeneID	83889.
KEGG	hsa:83889.
UCSC	uc010efu.2. human.
Organism-specific databases
CTD	83889.
GeneCards	GC19M038376.
HGNC	HGNC:29934. WDR87.
HPA	HPA048269. HPA049455.
neXtProt	NX_Q6ZQQ6.
PharmGKB	PA145147633.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG129648.
HOGENOM	HOG000169123.
InParanoid	Q6ZQQ6.
Enzyme and pathway databases
SignaLink	Q6ZQQ6.
Gene expression databases
ArrayExpress	Q6ZQQ6.
Bgee	Q6ZQQ6.
CleanEx	HS_WDR87.
Genevestigator	Q6ZQQ6.
Family and domain databases
Gene3D	2.130.10.10. 4 hits.
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR017986. WD40_repeat_dom. [Graphical view]
Pfam	PF00400. WD40. 2 hits. [Graphical view]
SMART	SM00320. WD40. 4 hits. [Graphical view]
SUPFAM	SSF50978. WD40_like. 1 hit.
PROSITE	PS00678. WD_REPEATS_1. False negative. PS50082. WD_REPEATS_2. 2 hits. PS50294. WD_REPEATS_REGION. 2 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	83889.
NextBio	72969.

Entry information

Entry name

WDR87_HUMAN

Accession

Primary (citable) accession number: Q6ZQQ6
Secondary accession number(s): Q9BWV9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 18, 2010
Last modified:	May 29, 2013
This is version 77 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.