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Protein
Submitted name:

MKIAA0049 protein

Gene

Nbr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
MKIAA0049 proteinImported
Submitted name:
Neighbor of Brca1 gene 1, isoform CRA_cImported
Gene namesi
Name:Nbr1Imported
Synonyms:mKIAA0049Imported
ORF Names:mCG_20206Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:108498. Nbr1.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099387.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 9583PB1InterPro annotationAdd
BLAST
Domaini221 – 26747ZZ-typeInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili305 – 33935Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains PB1 domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG4351. Eukaryota.
KOG4582. Eukaryota.
ENOG4111TKN. LUCA.
HOGENOMiHOG000220861.
HOVERGENiHBG052578.

Family and domain databases

InterProiIPR032350. N_BRCA1_central.
IPR000270. PB1_dom.
IPR000433. Znf_ZZ.
[Graphical view]
PfamiPF16158. N_BRCA1_IG. 1 hit.
PF00564. PB1. 1 hit.
PF00569. ZZ. 1 hit.
[Graphical view]
SMARTiSM00666. PB1. 1 hit.
SM00291. ZnF_ZZ. 1 hit.
[Graphical view]
PROSITEiPS51745. PB1. 1 hit.
PS01357. ZF_ZZ_1. 1 hit.
PS50135. ZF_ZZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6ZQK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LGLQLQPDSM EPQVTLNVTF KNETQSFLVS DPENTTWADV EAMVKVSFDL
60 70 80 90 100
NTIQIKYLDE ENEEISINSQ GEYEEALKMA NIKQGNQLQM QVHEGYHVVD
110 120 130 140 150
EALPKNVVEN QAAARTGKKP LAHYSSLVRV LGSDMKTTEE PAPEQCSSAP
160 170 180 190 200
CDTDQPQDKP PDWFTSYLEM FREQVVKETV EKLEQRLQEK LVLQKPLLSS
210 220 230 240 250
SPTEVSMPIS EETLFLPENQ FSWHIACSHC QKRIVGVRYQ CSLCPSYNIC
260 270 280 290 300
EDCEAGPYTH DTNHVLLKLR RPVVISSEPF FYSKYSAPRL PAALEQVRLQ
310 320 330 340 350
KQVDKNFVKA EKQRLRAEKK QRKAEVKELK KQLKLHRKIH LWNSIHGLQS
360 370 380 390 400
PKSPLGRPES LLQSNTLMLP LQPCAPVMPT LSAAFVDENL PDGTHLQPGT
410 420 430 440 450
KFIKHWRMKN TGNVKWNTDT KLKFMWGNLT LASTEKKDVL VPCLKAGHVG
460 470 480 490 500
VVSVEFIAPT LEGTYTSHWR LSHKGQQFGP RVWCSIIVDP FPSSESPDNV
510 520 530 540 550
EGDRISSSKA DDFSCEQEEA FLLAEEEIPL GEVTKQTEGT GASASQKTRR
560 570 580 590 600
AASERELYIP SVDLLTAQDL LSFELLDINI VQELERVPHN TPVDMTPCMS
610 620 630 640 650
PLPHDSPLIE KPGLGQIQEE SEGAGFKAPP DSTVSAKRKA ETPASVEETE
660 670 680 690 700
EDLSGTQFVC ETVIRSLTLD AAPDHNPPCR QRSPQRELQL YSTEGQQPLV
710 720 730 740 750
LPGFCRKDSS LKFALPEEGP RGDEREEIVH IVEEEVVEEE EEVQDEEVQS
760 770 780 790 800
QSSASSEDYI IILPECFDTS RPLGDSMYSS ALSQPGLERG AEGEPGIESG
810 820 830 840 850
LEPTEARERL PERESQPQEQ SISDILTTSQ PLDTVPLVPE VAGLPAALSR
860 870 880 890 900
SAPCGQCESS GVDSPGVDSP ATMHEVPPAP DDIRGEPRGS TGLANSRQRS
910
CDHSSPSFLK IRPQP
Length:915
Mass (Da):101,813
Last modified:July 5, 2004 - v1
Checksum:i86C520F6463D2D82
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129043 mRNA. Translation: BAC97853.1.
CH466558 Genomic DNA. Translation: EDL34056.1.
RefSeqiNP_001239152.1. NM_001252223.1.
UniGeneiMm.489817.
Mm.784.

Genome annotation databases

GeneIDi17966.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129043 mRNA. Translation: BAC97853.1.
CH466558 Genomic DNA. Translation: EDL34056.1.
RefSeqiNP_001239152.1. NM_001252223.1.
UniGeneiMm.489817.
Mm.784.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099387.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi17966.

Organism-specific databases

CTDi4077.
MGIiMGI:108498. Nbr1.

Phylogenomic databases

eggNOGiKOG4351. Eukaryota.
KOG4582. Eukaryota.
ENOG4111TKN. LUCA.
HOGENOMiHOG000220861.
HOVERGENiHBG052578.

Miscellaneous databases

ChiTaRSiNbr1. mouse.
NextBioi292899.
SOURCEiSearch...

Family and domain databases

InterProiIPR032350. N_BRCA1_central.
IPR000270. PB1_dom.
IPR000433. Znf_ZZ.
[Graphical view]
PfamiPF16158. N_BRCA1_IG. 1 hit.
PF00564. PB1. 1 hit.
PF00569. ZZ. 1 hit.
[Graphical view]
SMARTiSM00666. PB1. 1 hit.
SM00291. ZnF_ZZ. 1 hit.
[Graphical view]
PROSITEiPS51745. PB1. 1 hit.
PS01357. ZF_ZZ_1. 1 hit.
PS50135. ZF_ZZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
    DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Embryonic tailImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ6ZQK3_MOUSE
AccessioniPrimary (citable) accession number: Q6ZQK3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 11, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.