Zbtb21

Functionⁱ

GO - Molecular functionⁱ

methyl-CpG binding Source: MGI

Complete GO annotation...

GO - Biological processⁱ

negative regulation of transcription, DNA-templated Source: MGI

Complete GO annotation...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MKIAA1227 proteinImported
Gene namesⁱ	Name:Zbtb21Imported Synonyms:mKIAA1227Imported, Zfp295Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:1927240. Zbtb21.

Subcellular locationⁱ

GO - Cellular componentⁱ

cytosol Source: MGI
nucleoplasm Source: MGI
nucleus Source: MGI

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q6ZPV6.

PaxDbⁱ

Q6ZPV6.

PTM databases

iPTMnetⁱ	Q6ZPV6.
PhosphoSitePlusⁱ	Q6ZPV6.

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q6ZPV6. MM.

Genevisibleⁱ

Q6ZPV6. MM.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6ZPV6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	38 – 104	BTB (POZ)InterPro annotationAdd BLAST	67
Domainⁱ	557 – 585	C2H2-typeInterPro annotationAdd BLAST	29
Domainⁱ	681 – 708	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	785 – 813	C2H2-typeInterPro annotationAdd BLAST	29
Domainⁱ	917 – 944	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	945 – 972	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	1051 – 1074	C2H2-typeInterPro annotationAdd BLAST	24

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
HOGENOMⁱ	HOG000237324.
HOVERGENⁱ	HBG056929.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210. BTB/POZ_dom. IPR011333. SKP1/BTB/POZ. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00651. BTB. 1 hit.
SMARTⁱ	View protein in SMART SM00225. BTB. 1 hit. SM00355. ZnF_C2H2. 8 hits.
SUPFAMⁱ	SSF54695. SSF54695. 1 hit. SSF57667. SSF57667. 6 hits.
PROSITEⁱ	View protein in PROSITE PS50097. BTB. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits.

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q6ZPV6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
RNSEIKCRME GLLHYINPAH AISLLSALNE ERLKGQLCDV LLIVGDQKFR 
        60         70         80         90        100
AHKNVLAASS EYFQSLFTNK ENEAQTVFQL DFCEPDAFDN VLNYIYSSSL 
       110        120        130        140        150
FVEKGSLAAV QELGYSLGIS FLTNIVAKAP QAPFPACPNR KRVPVEDDET 
       160        170        180        190        200
SSQKRSVIVC QGRSEVPGKA SGPAMQDLSH TARASPSASV KTTISKPHVA 
       210        220        230        240        250
KPPEQLHSLP LTEKSWTKDS AAVYAKSLEQ AGALDDPNRG SLVKRNTVLP 
       260        270        280        290        300
PKPSQDREAT DDKPGVSSQL PKGKAIELAL KRPRPPVLSL HSSSETPYLL 
       310        320        330        340        350
KETSKGGGQG EDRNLLYYSK LGLVVPSGGP ASANQSIDRS GPLVKSLLRR 
       360        370        380        390        400
SLSMDSQVPV YSPSIDLKSS QGSSTAANEA PGSVFCSMSQ KSSLKDCSEK 
       410        420        430        440        450
KALDDRPQVL QPHRLRSFSA SQSTDREEAS PVTEVRIKTE PSSPLSDPSD 
       460        470        480        490        500
IIRVTVGGDA AAAAVAAAAA AAATRDLPLK TEEDQRDMSR LPAKRRFQTD 
       510        520        530        540        550
RRSPLKKAKA NEHGPAVSEE NCEEGRSPPS LDSNFPDSDL NREEFGELEG 
       560        570        580        590        600
TRPNKKFKCK HCLKIFRSTA GLHRHVNMYH NPEKPYACDI CHKRFHTNFK 
       610        620        630        640        650
VWTHCQTQHG IVKNPSPASS SHAVLDEKFQ RKLIDIVRER EIKKALIIKL 
       660        670        680        690        700
RRSKPGFQGQ SSSPAQQVIK RNLRSRAKGA YICAYCGKAY RFLSQFKQHI 
       710        720        730        740        750
KMHPGERPLG VSRAAKPKER ALARAVENKE VYPCRLCNAK LSSLLEQGNH 
       760        770        780        790        800
ERLCRNATVC PYCSLRFFSP ALKQEHEDRC EYKKLTCLEC MRTFKSSFSI 
       810        820        830        840        850
WRHQVEVHNQ NNMALAENFA LATLDHNGEV AAASRPQTEP SKVNHVATPK 
       860        870        880        890        900
EDTAFSDSSE QVNFDSEDSS CLPEDLSLSK QLKVQVKEEP VEEAEEEAPE 
       910        920        930        940        950
ASAAPREAGP SKETGLWPCE KCGKMFTAHK QLERHQELLC SVKPFICHVC 
       960        970        980        990       1000
YKAFRTNFRL WSHFQTHMSQ ATEEPVQKES EVCPVPTNSP SPPPLPPPPP 
      1010       1020       1030       1040       1050
LPKIQPLEPD SPTGLPENPT PATEKLFAPQ ESDTLFYHAP PLSAITFKRQ 
      1060       1070 
FMCKLCHRTF KTAFSLWSHE QTHN

Length:1,074

Mass (Da):119,131

Last modified:July 5, 2004 - v1

Checksum:ⁱBF524487A0CBA605

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK129313 mRNA. Translation: BAC98123.1.
UniGeneⁱ	Mm.474489.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK129313 mRNA. Translation: BAC98123.1.
UniGeneⁱ	Mm.474489.

3D structure databases

ProteinModelPortalⁱ	Q6ZPV6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

PTM databases

iPTMnetⁱ	Q6ZPV6.
PhosphoSitePlusⁱ	Q6ZPV6.

Proteomic databases

PaxDbⁱ	Q6ZPV6.

PaxDbⁱ

Q6ZPV6.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Organism-specific databases

MGIⁱ	MGI:1927240. Zbtb21.

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
HOGENOMⁱ	HOG000237324.
HOVERGENⁱ	HBG056929.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Genevisibleⁱ	Q6ZPV6. MM.

Genevisibleⁱ

Q6ZPV6. MM.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210. BTB/POZ_dom. IPR011333. SKP1/BTB/POZ. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00651. BTB. 1 hit.
SMARTⁱ	View protein in SMART SM00225. BTB. 1 hit. SM00355. ZnF_C2H2. 8 hits.
SUPFAMⁱ	SSF54695. SSF54695. 1 hit. SSF57667. SSF57667. 6 hits.
PROSITEⁱ	View protein in PROSITE PS50097. BTB. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6ZPV6_MOUSE
Accessionⁱ	Q6ZPV6Primary (citable) accession number: Q6ZPV6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	July 5, 2017
	This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB

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UniRef

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Supporting data

UniProtKB - Q6ZPV6 (Q6ZPV6_MOUSE)

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MKIAA1227 protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

PTM databases

Proteomic databases

Protocols and materials databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ