SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6ZPU3

- Q6ZPU3_MOUSE

UniProt

Q6ZPU3 - Q6ZPU3_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: MKIAA1303 protein
Gene
Rptor, mKIAA1303
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. RNA polymerase III type 1 promoter DNA binding Source: Ensembl
  2. RNA polymerase III type 2 promoter DNA binding Source: Ensembl
  3. RNA polymerase III type 3 promoter DNA binding Source: Ensembl
Complete GO annotation...

GO - Biological processi

  1. TOR signaling Source: Ensembl
  2. cell growth Source: Ensembl
  3. cellular response to amino acid stimulus Source: Ensembl
  4. cellular response to nutrient levels Source: Ensembl
  5. positive regulation of TOR signaling Source: Ensembl
  6. positive regulation of endothelial cell proliferation Source: Ensembl
  7. positive regulation of protein serine/threonine kinase activity Source: Ensembl
  8. positive regulation of transcription from RNA polymerase III promoter Source: Ensembl
  9. regulation of cell size Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_213550. HSF1-dependent transactivation.
REACT_220701. Regulation of AMPK activity via LKB1.

Names & Taxonomyi

Protein namesi
Submitted name:
MKIAA1303 proteinImported
Gene namesi
Name:RptorImported
Synonyms:mKIAA1303Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1921620. Rptor.

Subcellular locationi

GO - Cellular componenti

  1. TORC1 complex Source: MGI
  2. lysosomal membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ6ZPU3.
GenevestigatoriQ6ZPU3.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026671.

Structurei

3D structure databases

ProteinModelPortaliQ6ZPU3.

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

InParanoidiQ6ZPU3.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR004083. Raptor.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PANTHERiPTHR12848. PTHR12848. 1 hit.
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6ZPU3-1 [UniParc]FASTAAdd to Basket

« Hide

SARYFAQPVM KIPEEHDLES QIRKEREWRF LRNTRVRKQA QQVIQKGITR    50
LDDQIFLNRN PGVPSVVKFH PFTPCIAVAD KDSICFWDWE KGEKLDYFHN 100
GNPRYTRVTA MEYLNGQDCS LLLTATDDGA IRVWKNFADL EKNPEMVTAW 150
QGLSDMLPTT RGAGMVVDWE QETGLLMSSG DVRIVRIWDT DRETKVQDIP 200
TGADSCVTSL SCDSHRSLIV AGLGDGSIRV YDRRMALSEC RVMTYREHTA 250
WVVKAYLQKH PEGHIVSVSV NGDVRFFDPR MPESVNVMQI VKGLTALDIH 300
PQANLIACGS MNQFTAIYNG NGELINNIKY YDGFMGQRVG AISCLAFHPH 350
WPHLAVGSND YYISVYSVEK RVR 373
Length:373
Mass (Da):42,468
Last modified:July 5, 2004 - v1
Checksum:iEB0D62D2B0F091F5
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK129326 mRNA. Translation: BAC98136.1.
UniGeneiMm.209933.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK129326 mRNA. Translation: BAC98136.1 .
UniGenei Mm.209933.

3D structure databases

ProteinModelPortali Q6ZPU3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000026671.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1921620. Rptor.

Phylogenomic databases

InParanoidi Q6ZPU3.

Enzyme and pathway databases

Reactomei REACT_213550. HSF1-dependent transactivation.
REACT_220701. Regulation of AMPK activity via LKB1.

Miscellaneous databases

ChiTaRSi RPTOR. mouse.
SOURCEi Search...

Gene expression databases

Bgeei Q6ZPU3.
Genevestigatori Q6ZPU3.

Family and domain databases

Gene3Di 2.130.10.10. 2 hits.
InterProi IPR004083. Raptor.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view ]
PANTHERi PTHR12848. PTHR12848. 1 hit.
Pfami PF00400. WD40. 2 hits.
[Graphical view ]
SMARTi SM00320. WD40. 7 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
PROSITEi PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
    DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Embryonic tailImported.

Entry informationi

Entry nameiQ6ZPU3_MOUSE
AccessioniPrimary (citable) accession number: Q6ZPU3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi