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Protein

Testis-expressed protein 2

Gene

Tex2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processLipid transport, Transport
LigandLipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed protein 2
Gene namesi
Name:Tex2
Synonyms:Kiaa1738
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:102465 Tex2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei473 – 493HelicalSequence analysisAdd BLAST21
Transmembranei495 – 515HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002444801 – 1128Testis-expressed protein 2Add BLAST1128

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei195PhosphoserineBy similarity1
Modified residuei261PhosphothreonineCombined sources1
Modified residuei264PhosphoserineCombined sources1
Modified residuei265PhosphoserineCombined sources1
Modified residuei269PhosphoserineCombined sources1
Modified residuei294PhosphoserineCombined sources1
Glycosylationi593N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei733PhosphoserineBy similarity1
Modified residuei739PhosphoserineBy similarity1
Modified residuei745PhosphoserineBy similarity1
Modified residuei749PhosphoserineCombined sources1
Modified residuei752PhosphoserineCombined sources1
Modified residuei799PhosphoserineCombined sources1
Modified residuei816PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

EPDiQ6ZPJ0
MaxQBiQ6ZPJ0
PaxDbiQ6ZPJ0
PeptideAtlasiQ6ZPJ0
PRIDEiQ6ZPJ0

PTM databases

iPTMnetiQ6ZPJ0
PhosphoSitePlusiQ6ZPJ0

Expressioni

Gene expression databases

BgeeiENSMUSG00000040548
CleanExiMM_TEX2
ExpressionAtlasiQ6ZPJ0 baseline and differential
GenevisibleiQ6ZPJ0 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041985

Structurei

3D structure databases

ProteinModelPortaliQ6ZPJ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini817 – 1102SMP-LTDPROSITE-ProRule annotationAdd BLAST286

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi43 – 51Poly-Glu9
Compositional biasi134 – 195Ser-richAdd BLAST62
Compositional biasi817 – 822Poly-Glu6
Compositional biasi1040 – 1043Poly-Pro4

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2238 Eukaryota
ENOG410Z3SZ LUCA
GeneTreeiENSGT00390000000463
HOGENOMiHOG000049176
HOVERGENiHBG062867
InParanoidiQ6ZPJ0
OMAiLGRIFWD
OrthoDBiEOG091G01R4
PhylomeDBiQ6ZPJ0
TreeFamiTF314900

Family and domain databases

InterProiView protein in InterPro
IPR031468 SMP_LBD
PROSITEiView protein in PROSITE
PS51847 SMP, 1 hit

Sequencei

Sequence statusi: Complete.

Q6ZPJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSLNGRHAE KTIDMPKPSA PKVHVQRSVS RDTIAIHFSA SGEEEEEEEE
60 70 80 90 100
EFRGYLEEGL DDQSIVTGLE AKEDLYLESQ GGHDPAGPVS TAPADGLSVS
110 120 130 140 150
ESPAILPVSE NTVKLLESPA PALQVLSPVP LALSPGSSSS GPLASSPSVS
160 170 180 190 200
SLSEQKTSSS SPLSSPSKSP VLSSSASSSA LSSAKPFMSL VKSLSTEVEP
210 220 230 240 250
KESPHPPRHR HLMKTLVKSL STDTSRQESD TVSYKPPDSK LNLHLFKQFT
260 270 280 290 300
QPRNTGGDSK TAPSSPLTSP SDTRSFFKVP EMEAKIEDTK RRLSEVIYEP
310 320 330 340 350
FQLLSKIIGE ESGSHRPKAL SASASELSSL SGLNGHLESN NYSIKEEEGD
360 370 380 390 400
SEGEGYGSDS NTSRSDHLKP TEDASKEVEP KGSQASSLKD LGLKTSSLVL
410 420 430 440 450
EKCSLSALVS KEDEEFCELY TEDFELETEG EGRLDKTLDL PLKPEVLASD
460 470 480 490 500
GVALESEDEE DSATEHQELP VKTLGFFIMC VYAYLILPLP YYMSGLFLGV
510 520 530 540 550
GLGFMTAVCM IWFFTPPSAH KHHKSLKALR HQSTRSLDIK EPEILKGWMN
560 570 580 590 600
EIYNYDPETY HATLTHSVFV RLEGGTLRLS KPNKNISRRA SYNETKPEVT
610 620 630 640 650
YISQKIYDLS DSKIYLVPKS LARKRIWNKK YPICIELGRQ DDFMSKAQSD
660 670 680 690 700
KEATEEKPPP EKELPSEDLK KPPQPQEGTK SSQRDPILYL FGRTGREKEE
710 720 730 740 750
WFRRFILASR LKSELRKPAG VSGSKSGLLP AHSRHSSPSG HLSHSRSSSK
760 770 780 790 800
GSVEEMMSQP KQKELVGSVR QKMLLDYSVY MGRCVPQDNR SPHRSPVQSA
810 820 830 840 850
ESSPTASKKL PEAPPSEEEE QEAWVNALLG RIFWDFLGEK YWSDVVSKKI
860 870 880 890 900
QMKLSKIKLP YFMNELTLTE LDMGVAVPKI LQAFKPYVDH QGLWIDLEMS
910 920 930 940 950
YNGSFLMTLE TKMNLTKLGK EPLVEALKVG EIGKEGCRPR AYCLADSDEE
960 970 980 990 1000
SSSAGSSEED DPPEPTAGDK QPLPGAEGYV GGHRTSKIMR FVDKITKSKY
1010 1020 1030 1040 1050
FQKATETEFI KKKIEEVSNT PLLLTVEVQE CRGTLAVNIP PPPTDRIWYG
1060 1070 1080 1090 1100
FRKPPYVELK ARPKLGEREV TLVHVTEWIE KKLEQELQKV FVMPNMDDVY
1110 1120
IPIMHSAMDP RSTSCLLKEP PVETSDQL
Length:1,128
Mass (Da):125,226
Last modified:June 27, 2006 - v2
Checksum:i38C2201896B5E479
GO

Sequence cautioni

The sequence BAC98244 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129434 mRNA Translation: BAC98244.1 Different initiation.
AL663053 Genomic DNA No translation available.
CCDSiCCDS25557.1
RefSeqiNP_938034.2, NM_198292.3
XP_006533206.1, XM_006533143.3
XP_006533207.1, XM_006533144.3
XP_006533208.1, XM_006533145.1
XP_006533209.1, XM_006533146.3
XP_006533210.1, XM_006533147.3
UniGeneiMm.102407

Genome annotation databases

EnsembliENSMUST00000042780; ENSMUSP00000041985; ENSMUSG00000040548
GeneIDi21763
KEGGimmu:21763
UCSCiuc007lzb.1 mouse

Similar proteinsi

Entry informationi

Entry nameiTEX2_MOUSE
AccessioniPrimary (citable) accession number: Q6ZPJ0
Secondary accession number(s): B1ATR1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: May 23, 2018
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health