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Q6ZNQ5

- Q6ZNQ5_HUMAN

UniProt

Q6ZNQ5 - Q6ZNQ5_HUMAN

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Protein
Submitted name:

cDNA FLJ27339 fis, clone TMS09615, highly similar to TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent DNA helicase activity Source: InterPro
  3. DNA binding Source: InterPro

GO - Biological processi

  1. nucleotide-excision repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HelicaseSAAS annotationImported, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ27339 fis, clone TMS09615, highly similar to TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ6ZNQ5.

Structurei

3D structure databases

ProteinModelPortaliQ6ZNQ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains helicase ATP-binding domain.SAAS annotation

Family and domain databases

InterProiIPR006555. ATP-dep_Helicase_C.
IPR013020. DNA_helicase_DNA-repair_Rad3.
IPR010643. DUF1227.
IPR001945. XPGD_DNA_repair.
[Graphical view]
PfamiPF06777. DUF1227. 1 hit.
PF13307. Helicase_C_2. 1 hit.
[Graphical view]
PRINTSiPR00852. XRODRMPGMNTD.
SMARTiSM00491. HELICc2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00604. rad3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6ZNQ5-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MRQWLFVTCR CTAWGCKFPK QAQCPPSLSA HCLGRQARDR RDGGGRAAGP
60 70 80 90 100
AHASVCPPTP SLLPARFCAE RLRSLLHTLE ITDLADFSPL TLLANFATLV
110 120 130 140 150
STYAKGFTII IEPFDDRTPT IANPILHFSC MDASLAIKPV FERFQSVIIT
160 170 180 190 200
SGTLSPLDIY PKILDFHPVT MATFTMTLAR VCLCPMIIGR GNDQVAISSK
210 220 230 240 250
LETREDIAVI RNYGNLLLEM SAVVPDGIVA FFTSYQYMES TVASWYEQGI
260 270 280 290 300
LENIQRNKLL FIETQDGAET SVALEKYQEA CENGRGAILL SVARGKVSEG
310 320 330 340 350
IDFVHHYGRA VIMFGVPYVY TQSRILKARL EYLRDQFQIR ENDFLTFDAM
360 370 380 390 400
RHAAQCVGRA IRGKTDYGLM VFADKRFARG DKRGKLPRWI QEHLTDANLN
410 420 430 440 450
LTVDEGVQVA KYFLRQMAQP FHREDQLGLS LLSLEQLESE ETLQRIEQIA

QQL
Length:453
Mass (Da):50,971
Last modified:July 5, 2004 - v1
Checksum:i2406B5BD7BA85858
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK130849 mRNA. Translation: BAC85446.1.
UniGeneiHs.487294.

Genome annotation databases

UCSCiuc002pbh.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK130849 mRNA. Translation: BAC85446.1 .
UniGenei Hs.487294.

3D structure databases

ProteinModelPortali Q6ZNQ5.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6ZNQ5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc002pbh.2. human.

Family and domain databases

InterProi IPR006555. ATP-dep_Helicase_C.
IPR013020. DNA_helicase_DNA-repair_Rad3.
IPR010643. DUF1227.
IPR001945. XPGD_DNA_repair.
[Graphical view ]
Pfami PF06777. DUF1227. 1 hit.
PF13307. Helicase_C_2. 1 hit.
[Graphical view ]
PRINTSi PR00852. XRODRMPGMNTD.
SMARTi SM00491. HELICc2. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00604. rad3. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project."
    Kawakami B., Sugiyama A., Takemoto M., Suzuki Y., Hata H., Nakagawa K., Mizuno S., Morinaga M., Kawamura M., Sugiyama T., Irie R., Otsuki T., Sato H., Nishikawa T., Nagai K., Isogai T., Sugano S.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ThymusImported.

Entry informationi

Entry nameiQ6ZNQ5_HUMAN
AccessioniPrimary (citable) accession number: Q6ZNQ5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.