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Protein
Submitted name:

cDNA FLJ27339 fis, clone TMS09615, highly similar to TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ27339 fis, clone TMS09615, highly similar to TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiQ6ZNQ5.
PaxDbiQ6ZNQ5.
PeptideAtlasiQ6ZNQ5.
PRIDEiQ6ZNQ5.

Structurei

3D structure databases

ProteinModelPortaliQ6ZNQ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini235 – 379HELICc2InterPro annotationAdd BLAST145

Phylogenomic databases

eggNOGiKOG1131. Eukaryota.
COG1199. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR006555. ATP-dep_Helicase_C.
IPR013020. DNA_helicase_DNA-repair_Rad3.
IPR010643. HBB.
IPR001945. RAD3/XPD.
PfamiView protein in Pfam
PF06777. HBB. 1 hit.
PF13307. Helicase_C_2. 1 hit.
PRINTSiPR00852. XRODRMPGMNTD.
SMARTiView protein in SMART
SM00491. HELICc2. 1 hit.
TIGRFAMsiTIGR00604. rad3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6ZNQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQWLFVTCR CTAWGCKFPK QAQCPPSLSA HCLGRQARDR RDGGGRAAGP
60 70 80 90 100
AHASVCPPTP SLLPARFCAE RLRSLLHTLE ITDLADFSPL TLLANFATLV
110 120 130 140 150
STYAKGFTII IEPFDDRTPT IANPILHFSC MDASLAIKPV FERFQSVIIT
160 170 180 190 200
SGTLSPLDIY PKILDFHPVT MATFTMTLAR VCLCPMIIGR GNDQVAISSK
210 220 230 240 250
LETREDIAVI RNYGNLLLEM SAVVPDGIVA FFTSYQYMES TVASWYEQGI
260 270 280 290 300
LENIQRNKLL FIETQDGAET SVALEKYQEA CENGRGAILL SVARGKVSEG
310 320 330 340 350
IDFVHHYGRA VIMFGVPYVY TQSRILKARL EYLRDQFQIR ENDFLTFDAM
360 370 380 390 400
RHAAQCVGRA IRGKTDYGLM VFADKRFARG DKRGKLPRWI QEHLTDANLN
410 420 430 440 450
LTVDEGVQVA KYFLRQMAQP FHREDQLGLS LLSLEQLESE ETLQRIEQIA

QQL
Length:453
Mass (Da):50,971
Last modified:July 5, 2004 - v1
Checksum:i2406B5BD7BA85858
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK130849 mRNA. Translation: BAC85446.1.
UniGeneiHs.487294.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ6ZNQ5_HUMAN
AccessioniPrimary (citable) accession number: Q6ZNQ5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 5, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.