Q6ZNQ5 (Q6ZNQ5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ27339 fis, clone TMS09615, highly similar to TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) EMBL BAC85446.1
Organism	Homo sapiens (Human) EMBL BAC85446.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	453 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + H2O = ADP + phosphate.
Sequence similarities	Contains 1 helicase ATP-binding domain. SAAS SAAS013020

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS006555
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase SAAS SAAS013020 EMBL BAC85446.1 Hydrolase
Gene Ontology (GO)
Biological_process	nucleotide-excision repair Inferred from electronic annotation. Source: InterPro
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent DNA helicase activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6ZNQ5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 2406B5BD7BA85858	FASTA	453	50,971
	10 20 30 40 50 60 MRQWLFVTCR CTAWGCKFPK QAQCPPSLSA HCLGRQARDR RDGGGRAAGP AHASVCPPTP 70 80 90 100 110 120 SLLPARFCAE RLRSLLHTLE ITDLADFSPL TLLANFATLV STYAKGFTII IEPFDDRTPT 130 140 150 160 170 180 IANPILHFSC MDASLAIKPV FERFQSVIIT SGTLSPLDIY PKILDFHPVT MATFTMTLAR 190 200 210 220 230 240 VCLCPMIIGR GNDQVAISSK LETREDIAVI RNYGNLLLEM SAVVPDGIVA FFTSYQYMES 250 260 270 280 290 300 TVASWYEQGI LENIQRNKLL FIETQDGAET SVALEKYQEA CENGRGAILL SVARGKVSEG 310 320 330 340 350 360 IDFVHHYGRA VIMFGVPYVY TQSRILKARL EYLRDQFQIR ENDFLTFDAM RHAAQCVGRA 370 380 390 400 410 420 IRGKTDYGLM VFADKRFARG DKRGKLPRWI QEHLTDANLN LTVDEGVQVA KYFLRQMAQP 430 440 450 FHREDQLGLS LLSLEQLESE ETLQRIEQIA QQL

References

[1]	"NEDO human cDNA sequencing project." Kawakami B., Sugiyama A., Takemoto M., Suzuki Y., Hata H., Nakagawa K., Mizuno S., Morinaga M., Kawamura M., Sugiyama T., Irie R., Otsuki T., Sato H., Nishikawa T., Nagai K., Isogai T., Sugano S. Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Thymus EMBL BAC85446.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK130849 mRNA. Translation: BAC85446.1.
IPI	IPI00745711.
UniGene	Hs.487294.
3D structure databases
ProteinModelPortal	Q6ZNQ5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6ZNQ5.
Proteomic databases
PRIDE	Q6ZNQ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc002pbh.2. human.
Family and domain databases
InterPro	IPR006555. ATP-dep_Helicase_C. IPR013020. DNA_helicase_DNA-repair_Rad3. IPR010643. DUF1227. IPR001945. XPGD_DNA_repair. [Graphical view]
Pfam	PF06777. DUF1227. 1 hit. PF13307. Helicase_C_2. 1 hit. [Graphical view]
PRINTS	PR00852. XRODRMPGMNTD.
SMART	SM00491. HELICc2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00604. rad3. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6ZNQ5_HUMAN

Accession

Primary (citable) accession number: Q6ZNQ5

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	October 3, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.