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Q6ZNQ5

- Q6ZNQ5_HUMAN

UniProt

Q6ZNQ5 - Q6ZNQ5_HUMAN

Protein
Submitted name:

cDNA FLJ27339 fis, clone TMS09615, highly similar to TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + H2O = ADP + phosphate.SAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. ATP-dependent DNA helicase activity Source: InterPro
    3. DNA binding Source: InterPro

    GO - Biological processi

    1. nucleotide-excision repair Source: InterPro

    Keywords - Molecular functioni

    HelicaseSAAS annotationImported, Hydrolase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ27339 fis, clone TMS09615, highly similar to TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-KW

    Keywords - Cellular componenti

    NucleusSAAS annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiQ6ZNQ5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6ZNQ5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains helicase ATP-binding domain.SAAS annotation

    Family and domain databases

    InterProiIPR006555. ATP-dep_Helicase_C.
    IPR013020. DNA_helicase_DNA-repair_Rad3.
    IPR010643. DUF1227.
    IPR001945. XPGD_DNA_repair.
    [Graphical view]
    PfamiPF06777. DUF1227. 1 hit.
    PF13307. Helicase_C_2. 1 hit.
    [Graphical view]
    PRINTSiPR00852. XRODRMPGMNTD.
    SMARTiSM00491. HELICc2. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00604. rad3. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6ZNQ5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRQWLFVTCR CTAWGCKFPK QAQCPPSLSA HCLGRQARDR RDGGGRAAGP    50
    AHASVCPPTP SLLPARFCAE RLRSLLHTLE ITDLADFSPL TLLANFATLV 100
    STYAKGFTII IEPFDDRTPT IANPILHFSC MDASLAIKPV FERFQSVIIT 150
    SGTLSPLDIY PKILDFHPVT MATFTMTLAR VCLCPMIIGR GNDQVAISSK 200
    LETREDIAVI RNYGNLLLEM SAVVPDGIVA FFTSYQYMES TVASWYEQGI 250
    LENIQRNKLL FIETQDGAET SVALEKYQEA CENGRGAILL SVARGKVSEG 300
    IDFVHHYGRA VIMFGVPYVY TQSRILKARL EYLRDQFQIR ENDFLTFDAM 350
    RHAAQCVGRA IRGKTDYGLM VFADKRFARG DKRGKLPRWI QEHLTDANLN 400
    LTVDEGVQVA KYFLRQMAQP FHREDQLGLS LLSLEQLESE ETLQRIEQIA 450
    QQL 453
    Length:453
    Mass (Da):50,971
    Last modified:July 5, 2004 - v1
    Checksum:i2406B5BD7BA85858
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK130849 mRNA. Translation: BAC85446.1.
    UniGeneiHs.487294.

    Genome annotation databases

    UCSCiuc002pbh.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK130849 mRNA. Translation: BAC85446.1 .
    UniGenei Hs.487294.

    3D structure databases

    ProteinModelPortali Q6ZNQ5.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q6ZNQ5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc002pbh.2. human.

    Family and domain databases

    InterProi IPR006555. ATP-dep_Helicase_C.
    IPR013020. DNA_helicase_DNA-repair_Rad3.
    IPR010643. DUF1227.
    IPR001945. XPGD_DNA_repair.
    [Graphical view ]
    Pfami PF06777. DUF1227. 1 hit.
    PF13307. Helicase_C_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00852. XRODRMPGMNTD.
    SMARTi SM00491. HELICc2. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00604. rad3. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project."
      Kawakami B., Sugiyama A., Takemoto M., Suzuki Y., Hata H., Nakagawa K., Mizuno S., Morinaga M., Kawamura M., Sugiyama T., Irie R., Otsuki T., Sato H., Nishikawa T., Nagai K., Isogai T., Sugano S.
      Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: ThymusImported.

    Entry informationi

    Entry nameiQ6ZNQ5_HUMAN
    AccessioniPrimary (citable) accession number: Q6ZNQ5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.