Q6ZNL6 (FGD5_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
FYVE, RhoGEF and PH domain-containing protein 5

Alternative name(s):
Zinc finger FYVE domain-containing protein 23

Gene names

Name:	FGD5
Synonyms:	ZFYVE23

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1462 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. Ref.6
Subcellular location	Cytoplasm › cytoskeleton. Cell projection › ruffle membrane. Endoplasmic reticulum. Golgi apparatus. Early endosome. Note: In peripheral membrane ruffles, colocolizes with F-actin. In confluent HUVECs, detected at cell-cell-contact sites where it colocalizes with vascular endothelial cadherin/CDH5. Ref.6
Tissue specificity	Expressed in endothelial cells (at protein level). Ref.6
Sequence similarities	Contains 1 DH (DBL-homology) domain. Contains 1 FYVE-type zinc finger. Contains 2 PH domains.
Sequence caution	The sequence BAC04878.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence BAC04989.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence BAC85128.1 differs from that shown. Reason: Frameshift at position 79. The sequence CAD98090.1 differs from that shown. Reason: Erroneous termination at position 1279. Translated as Lys.

Ontologies

Keywords
Cellular component	Cell membrane Cell projection Cytoplasm Cytoskeleton Endoplasmic reticulum Endosome Golgi apparatus Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat Zinc-finger
Ligand	Metal-binding Zinc
Molecular function	Guanine-nucleotide releasing factor
PTM	Phosphoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	actin cytoskeleton organization Inferred from sequence or structural similarity. Source: UniProtKB filopodium assembly Inferred from sequence or structural similarity. Source: UniProtKB regulation of Cdc42 GTPase activity Inferred from sequence or structural similarity. Source: UniProtKB regulation of cell shape Inferred from sequence or structural similarity. Source: UniProtKB
Cellular_component	Golgi apparatus Inferred from sequence or structural similarity. Source: UniProtKB cytoskeleton Inferred from electronic annotation. Source: UniProtKB-SubCell early endosome Inferred from electronic annotation. Source: UniProtKB-SubCell endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell lamellipodium Inferred from sequence or structural similarity. Source: UniProtKB ruffle Inferred from sequence or structural similarity. Source: UniProtKB ruffle membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	Rho guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: InterPro guanyl-nucleotide exchange factor activity Inferred from sequence or structural similarity. Source: UniProtKB metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phospholipid binding Inferred from electronic annotation. Source: InterPro small GTPase binding Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q6ZNL6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q6ZNL6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-922: Missing.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1462

1462

FYVE, RhoGEF and PH domain-containing protein 5

PRO_0000080950

Regions

Domain

892 – 1084

193

DH

Domain

1113 – 1207

95

PH 1

Domain

1363 – 1461

99

PH 2

Zinc finger

1242 – 1301

60

FYVE-type

Compositional bias

58 – 323

266

Glu-rich

Compositional bias

645 – 650

6

Poly-Lys

Amino acid modifications

Modified residue

632

1

Phosphoserine By similarity

Modified residue

635

1

Phosphoserine By similarity

Natural variations

Alternative sequence

1 – 922

922

Missing in isoform 2.

VSP_013088

Natural variant

403

1

G → R.
Corresponds to variant rs7636593 [ dbSNP | Ensembl ].

VAR_059799

Natural variant

828

1

A → T.
Corresponds to variant rs17038795 [ dbSNP | Ensembl ].

VAR_059800

Natural variant

941

1

E → K.
Corresponds to variant rs2307092 [ dbSNP | Ensembl ].

VAR_059801

Experimental info

Sequence conflict

124

1

A → T in BAC85128. Ref.1

Sequence conflict

213

1

A → G in BAC85128. Ref.1

Sequence conflict

354

1

S → G in CAE45896. Ref.5

Sequence conflict

574

1

H → Y in BAC04989. Ref.1

Sequence conflict

1112

1

R → M in CAE45896. Ref.5

Sequence conflict

1196

1

D → N in CAE45896. Ref.5

Sequence conflict

1289

1

M → T in CAE45896. Ref.5

Sequence conflict

1382

1

K → E in BAC04989. Ref.1

Sequence conflict

1400

1

D → G in CAD98090. Ref.5

Secondary structure

1

.

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1462

Helix Strand Turn

Details...

Helix

891 – 917

27

Helix

919 – 929

11

Helix

936 – 968

33

Turn

969 – 972

4

Helix

978 – 981

4

Turn

982 – 986

5

Helix

987 – 1008

22

Helix

1012 – 1022

11

Helix

1032 – 1054

23

Helix

1062 – 1084

23

Helix

1088 – 1100

13

Beta strand

1114 – 1116

3

Beta strand

1119 – 1124

6

Beta strand

1127 – 1145

19

Beta strand

1151 – 1158

8

Beta strand

1174 – 1179

6

Beta strand

1184 – 1188

5

Helix

1192 – 1204

13

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 18, 2010. Version 3. Checksum: 3012049C00F7384B	FASTA	1,462	159,891
	10 20 30 40 50 60 MFRGPKPPIA PKPRLTAPNE WRASVYLNDS LNKCSNGRLP CVDRGLDEGP RSIPKCSESE 70 80 90 100 110 120 TDEDYIVVPR VPLREDEPKD EGSVGNKALV SPESSAEEEE EREEGGEACG LEGTGAGEDS 130 140 150 160 170 180 VAPAAPGAGA LSREGEEGTD LALEDEGEGC ADEPGTLEQV SRSEEEEKLV QPHRECSLED 190 200 210 220 230 240 SGPWAGEGVF QSDLLLPHIH GEDQEPPDTP GEAEEDDEEG CASTDPAGAD EGSGPDRPTE 250 260 270 280 290 300 DMGQDAEDTS EEPPEKEELA GVQEAETATD CPEVLEEGCE EATGVTGGEQ VDLSEPPDHE 310 320 330 340 350 360 KKTNQEVAAA TLEDHAQDES AEESCQIVPF ENDCMEDFVT SLTGSPYEFF PTESTSFCSE 370 380 390 400 410 420 SCSPLSESAK GLESEQAPKL GLRAEENPMV GALCGQCGSL QGGAAEGPAA PDVVVVLEEE 430 440 450 460 470 480 ALDDALANPY VMGVGLPGQA APGEGGQAAS DALGGYGSKE ELNCEAEGGL VPADRKNTST 490 500 510 520 530 540 RVRPHSGKVA GYVPETVPEE TGPEAGSSAP GIGGAAEEVG KTLLSLEGKP LEASRALPAK 550 560 570 580 590 600 PRAFTLYPRS FSVEGREIPV SVYQEPEGSG LDDHRIKRKE DNLSLSCVIG SSGSFSQRNH 610 620 630 640 650 660 LPSSGTSTPS SMVDIPPPFD LACITKKPIT KSSPSLLIES DSPDKYKKKK SSFKRFLALT 670 680 690 700 710 720 FKKKTENKLH VDVNVSSSRS SSESSYHGPS RILEVDRRSL SNSPQLKSRT GKLRASESPS 730 740 750 760 770 780 SLIFYRDGKR KGVPFSRTVS RVESFEDRSR PPFLPLPLTK PRSISFPSAD TSDYENIPAM 790 800 810 820 830 840 NSDYENIQIP PRRPARAGAF TKLFEDQSRA LSTANENDGY VDMSSFNAFE SKQQSADQDA 850 860 870 880 890 900 ESAYTEPYKV CPISSAAPKE DLTSDEEQRS SEEEDSASRD PSVTHKVEGQ SRALVIAQEL 910 920 930 940 950 960 LSSEKAYVEM LQHLNLDFHG AVMRALDDMD HEGRDTLARE ELRQGLSELP AIHDLHQGIL 970 980 990 1000 1010 1020 EELEERLSNW ESQQKVADVF LAREQGFDHH ATHILQFDRY LGLLSENCLH SPRLAAAVRE 1030 1040 1050 1060 1070 1080 FEQSVQGGSQ TAKHRLLRVV QRLFQYQVLL TDYLNNLCPD SAEYDNTQGA LSLISKVTDR 1090 1100 1110 1120 1130 1140 ANDSMEQGEN LQKLVHIEHS VRGQGDLLQP GREFLKEGTL MKVTGKNRRP RHLFLMNDVL 1150 1160 1170 1180 1190 1200 LYTYPQKDGK YRLKNTLAVA NMKVSRPVME KVPYALKIET SESCLMLSAS SCAERDEWYG 1210 1220 1230 1240 1250 1260 CLSRALPEDY KAQALAAFHH SVEIRERLGV SLGERPPTLV PVTHVMMCMN CGCDFSLTLR 1270 1280 1290 1300 1310 1320 RHHCHACGKI VCRNCSRNKY PLKYLKDRMA KVCDGCFGEL KKRGRAVPGL MRERPVSMSF 1330 1340 1350 1360 1370 1380 PLSSPRFSGS AFSSVFQSIN PSTFKKQKKV PSALTEVAAS GEGSAISGYL SRCKRGKRHW 1390 1400 1410 1420 1430 1440 KKLWFVIKGK VLYTYMASED KVALESMPLL GFTIAPEKEE GSSEVGPIFH LYHKKTLFYS 1450 1460 FKAEDTNSAQ RWIEAMEDAS VL
	Isoform 2 [UniParc]. Checksum: A8ED7C2316625D0E	FASTA	540	61,238
	10 20 30 40 50 60 MRALDDMDHE GRDTLAREEL RQGLSELPAI HDLHQGILEE LEERLSNWES QQKVADVFLA 70 80 90 100 110 120 REQGFDHHAT HILQFDRYLG LLSENCLHSP RLAAAVREFE QSVQGGSQTA KHRLLRVVQR 130 140 150 160 170 180 LFQYQVLLTD YLNNLCPDSA EYDNTQGALS LISKVTDRAN DSMEQGENLQ KLVHIEHSVR 190 200 210 220 230 240 GQGDLLQPGR EFLKEGTLMK VTGKNRRPRH LFLMNDVLLY TYPQKDGKYR LKNTLAVANM 250 260 270 280 290 300 KVSRPVMEKV PYALKIETSE SCLMLSASSC AERDEWYGCL SRALPEDYKA QALAAFHHSV 310 320 330 340 350 360 EIRERLGVSL GERPPTLVPV THVMMCMNCG CDFSLTLRRH HCHACGKIVC RNCSRNKYPL 370 380 390 400 410 420 KYLKDRMAKV CDGCFGELKK RGRAVPGLMR ERPVSMSFPL SSPRFSGSAF SSVFQSINPS 430 440 450 460 470 480 TFKKQKKVPS ALTEVAASGE GSAISGYLSR CKRGKRHWKK LWFVIKGKVL YTYMASEDKV 490 500 510 520 530 540 ALESMPLLGF TIAPEKEEGS SEVGPIFHLY HKKTLFYSFK AEDTNSAQRW IEAMEDASVL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 77-1462 (ISOFORM 1). Tissue: Spleen and Testis.
[2]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Brain.
[4]	"Shotgun sequencing of the human transcriptome with ORF expressed sequence tags." Dias Neto E., Correa R.G., Verjovski-Almeida S., Briones M.R.S., Nagai M.A., da Silva W. Jr., Zago M.A., Bordin S., Costa F.F., Goldman G.H., Carvalho A.F., Matsukuma A., Baia G.S., Simpson D.H., Brunstein A., de Oliveira P.S.L., Bucher P., Jongeneel C.V. , O'Hare M.J., Soares F., Brentani R.R., Reis L.F.L., de Souza S.J., Simpson A.J.G. Proc. Natl. Acad. Sci. U.S.A. 97:3491-3496(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-215 (ISOFORM 1). Tissue: Placenta.
[5]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 318-1462 (ISOFORM 1). Tissue: Esophageal carcinoma and Uterus.
[6]	"FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells." Kurogane Y., Miyata M., Kubo Y., Nagamatsu Y., Kundu R.K., Uemura A., Ishida T., Quertermous T., Hirata K., Rikitake Y. Arterioscler. Thromb. Vasc. Biol. 32:988-996(2012) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[7]	"Crystal structure of the DH and PH-1 domains of human FGD5." Structural genomics consortium (SGC) Submitted (JUN-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 889-1304.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AK096856 mRNA. Translation: BAC04878.1. Different initiation.
AK097276 mRNA. Translation: BAC04989.1. Different initiation.
AK131078 mRNA. Translation: BAC85128.1. Frameshift.
AK123054 mRNA. Translation: BAG53865.1.
AC087591 Genomic DNA. No translation available.
AC090954 Genomic DNA. No translation available.
BC035364 mRNA. Translation: AAH35364.1.
BF989107 mRNA. No translation available.
BX640820 Transcribed RNA. Translation: CAE45896.2.
BX538312 mRNA. Translation: CAD98090.1. Sequence problems.

IPI

IPI00397955.
IPI00554548.

RefSeq

NP_689749.3. NM_152536.3.

UniGene

Hs.412406.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3MPX	X-ray	2.80	A	889-1304	[»]

ProteinModelPortal

Q6ZNL6.

SMR

Q6ZNL6. Positions 890-1205, 1245-1301, 1369-1461.

ModBase

Search...

Protein-protein interaction databases

STRING

9606.ENSP00000285046.

PTM databases

PhosphoSite

Q6ZNL6.

Polymorphism databases

DMDM

296439343.

Proteomic databases

PaxDb

Q6ZNL6.

PRIDE

Q6ZNL6.

Protocols and materials databases

DNASU

152273.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

Ensembl

ENST00000285046; ENSP00000285046; ENSG00000154783.

GeneID

152273.

KEGG

hsa:152273.

UCSC

uc003bzc.3. human.
uc003bzd.3. human.

Organism-specific databases

CTD

152273.

GeneCards

GC03P014860.

H-InvDB

HIX0003091.
HIX0003092.

HGNC

HGNC:19117. FGD5.

HPA

HPA014536.
HPA019191.

MIM

614788. gene.

neXtProt

NX_Q6ZNL6.

PharmGKB

PA134874843.

GenAtlas

Search...

Phylogenomic databases

eggNOG

NOG291216.

HOGENOM

HOG000168874.

HOVERGEN

HBG051609.

InParanoid

Q6ZNL6.

KO

K05724.

OMA

YVEMLQH.

OrthoDB

EOG4M65HM.

Gene expression databases

ArrayExpress

Q6ZNL6.

Bgee

Q6ZNL6.

CleanEx

HS_FGD5.

Genevestigator

Q6ZNL6.

GermOnline

ENSG00000154783. Homo sapiens.

Family and domain databases

Gene3D

1.20.900.10. 1 hit.
2.30.29.30. 2 hits.
3.30.40.10. 1 hit.

InterPro

IPR000219. DH-domain.
IPR011993. PH_like_dom.
IPR001849. Pleckstrin_homology.
IPR000306. Znf_FYVE.
IPR017455. Znf_FYVE-rel.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]

Pfam

PF01363. FYVE. 1 hit.
PF00169. PH. 2 hits.
PF00621. RhoGEF. 1 hit.
[Graphical view]

SMART

SM00064. FYVE. 1 hit.
SM00233. PH. 2 hits.
SM00325. RhoGEF. 1 hit.
[Graphical view]

SUPFAM

SSF48065. DH-domain. 1 hit.

PROSITE

PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 2 hits.
PS50178. ZF_FYVE. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q6ZNL6.

GenomeRNAi

152273.

NextBio

86934.

SOURCE

Search...

Entry information

Entry name

FGD5_HUMAN

Accession

Primary (citable) accession number: Q6ZNL6
Secondary accession number(s): B3KVQ3 , Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	May 18, 2010
Last modified:	May 1, 2013
This is version 95 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.