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Protein
Submitted name:

Tropomyosin 1 (Alpha), isoform CRA_f

Gene

TPM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tropomyosin 1 (Alpha), isoform CRA_fImported
Submitted name:
Tropomyosin alpha-1 chainImported
Submitted name:
cDNA FLJ16459 fis, clone BRCAN2002473, moderately similar to Tropomyosin, fibroblast isoform 2Imported
Gene namesi
Name:TPM1Imported
ORF Names:hCG_33495Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000140416.19
HGNCiHGNC:12010 TPM1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000140416

PTM / Processingi

Proteomic databases

MaxQBiQ6ZN40
PeptideAtlasiQ6ZN40
PRIDEiQ6ZN40

Expressioni

Gene expression databases

BgeeiENSG00000140416
ExpressionAtlasiQ6ZN40 baseline and differential

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 315Sequence analysisAdd BLAST315

Sequence similaritiesi

Belongs to the tropomyosin family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00550000074494
HOGENOMiHOG000231521
HOVERGENiHBG107404
OMAiQDKADTC
OrthoDBiEOG091G0UO7

Family and domain databases

InterProiView protein in InterPro
IPR000533 Tropomyosin
PfamiView protein in Pfam
PF00261 Tropomyosin, 1 hit
PRINTSiPR00194 TROPOMYOSIN
PROSITEiView protein in PROSITE
PS00326 TROPOMYOSIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q6ZN40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEDRSKQLE EDIAAKEKLL
60 70 80 90 100
RVSEDERDRV LEELHKAEDS LLAAEEAAAK LEDELVSLQK KLKGTEDELD
110 120 130 140 150
KYSEALKDAQ EKLELAEKKA TDAEADVASL NRRIQLVEEE LDRAQERLAT
160 170 180 190 200
ALQKLEEAEK AADESERGMK VIESRAQKDE EKMEIQEIQL KEAKHIAEDA
210 220 230 240 250
DRKYEEVARK LVIIESDLER AEERAELSEG KCAELEEELK TVTNNLKSLE
260 270 280 290 300
AQAEKYSQKE DRYEEEIKVL SDKLKEAETR AEFAERSVTK LEKSIDDLEE
310 320
KVAHAKEENL SMHQMLDQTL LELNNM
Length:326
Mass (Da):37,453
Last modified:July 5, 2004 - v1
Checksum:iB7FADB9BB1508DD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079328 Genomic DNA No translation available.
AK131384 mRNA Translation: BAD18535.1
CH471082 Genomic DNA Translation: EAW77624.1
RefSeqiXP_005254694.1, XM_005254637.1
UniGeneiHs.133892
Hs.602995

Genome annotation databases

EnsembliENST00000357980; ENSP00000350667; ENSG00000140416
GeneIDi7168
UCSCiuc002alm.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6ZN40_HUMAN
AccessioniPrimary (citable) accession number: Q6ZN40
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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