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Protein
Submitted name:

Tropomyosin 1 (Alpha), isoform CRA_f

Gene

TPM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tropomyosin 1 (Alpha), isoform CRA_fImported
Submitted name:
Tropomyosin alpha-1 chainImported
Submitted name:
cDNA FLJ16459 fis, clone BRCAN2002473, moderately similar to Tropomyosin, fibroblast isoform 2Imported
Gene namesi
Name:TPM1Imported
ORF Names:hCG_33495Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:12010. TPM1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000140416.

PTM / Processingi

Proteomic databases

MaxQBiQ6ZN40.
PeptideAtlasiQ6ZN40.
PRIDEiQ6ZN40.

Expressioni

Gene expression databases

BgeeiENSG00000140416.
ExpressionAtlasiQ6ZN40. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ6ZN40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 315Sequence analysisAdd BLAST315

Sequence similaritiesi

Belongs to the tropomyosin family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00550000074494.
HOGENOMiHOG000231521.
HOVERGENiHBG107404.
OMAiAGKLELX.
OrthoDBiEOG091G0UO7.
PhylomeDBiQ6ZN40.

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZN40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEDRSKQLE EDIAAKEKLL
60 70 80 90 100
RVSEDERDRV LEELHKAEDS LLAAEEAAAK LEDELVSLQK KLKGTEDELD
110 120 130 140 150
KYSEALKDAQ EKLELAEKKA TDAEADVASL NRRIQLVEEE LDRAQERLAT
160 170 180 190 200
ALQKLEEAEK AADESERGMK VIESRAQKDE EKMEIQEIQL KEAKHIAEDA
210 220 230 240 250
DRKYEEVARK LVIIESDLER AEERAELSEG KCAELEEELK TVTNNLKSLE
260 270 280 290 300
AQAEKYSQKE DRYEEEIKVL SDKLKEAETR AEFAERSVTK LEKSIDDLEE
310 320
KVAHAKEENL SMHQMLDQTL LELNNM
Length:326
Mass (Da):37,453
Last modified:July 5, 2004 - v1
Checksum:iB7FADB9BB1508DD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079328 Genomic DNA. No translation available.
AK131384 mRNA. Translation: BAD18535.1.
CH471082 Genomic DNA. Translation: EAW77624.1.
RefSeqiXP_005254694.1. XM_005254637.1.
UniGeneiHs.133892.
Hs.602995.

Genome annotation databases

EnsembliENST00000357980; ENSP00000350667; ENSG00000140416.
GeneIDi7168.
UCSCiuc002alm.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079328 Genomic DNA. No translation available.
AK131384 mRNA. Translation: BAD18535.1.
CH471082 Genomic DNA. Translation: EAW77624.1.
RefSeqiXP_005254694.1. XM_005254637.1.
UniGeneiHs.133892.
Hs.602995.

3D structure databases

ProteinModelPortaliQ6ZN40.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ6ZN40.
PeptideAtlasiQ6ZN40.
PRIDEiQ6ZN40.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000357980; ENSP00000350667; ENSG00000140416.
GeneIDi7168.
UCSCiuc002alm.4. human.

Organism-specific databases

CTDi7168.
HGNCiHGNC:12010. TPM1.
OpenTargetsiENSG00000140416.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00550000074494.
HOGENOMiHOG000231521.
HOVERGENiHBG107404.
OMAiAGKLELX.
OrthoDBiEOG091G0UO7.
PhylomeDBiQ6ZN40.

Miscellaneous databases

ChiTaRSiTPM1. human.
GenomeRNAii7168.

Gene expression databases

BgeeiENSG00000140416.
ExpressionAtlasiQ6ZN40. baseline and differential.

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6ZN40_HUMAN
AccessioniPrimary (citable) accession number: Q6ZN40
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.