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Q6ZN14

- Q6ZN14_HUMAN

UniProt

Q6ZN14 - Q6ZN14_HUMAN

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Protein
Submitted name: cDNA FLJ16524 fis, clone OCBBF2003327, moderately similar to ADAM-TS 6 (EC 3.4.24.-)
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metalloendopeptidase activity Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Protein family/group databases

    MEROPSiM12.235.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ16524 fis, clone OCBBF2003327, moderately similar to ADAM-TS 6 (EC 3.4.24.-)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. proteinaceous extracellular matrix Source: InterPro
    Complete GO annotation...

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA24537.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ6ZN14.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6ZN14.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000203663.
    KOiK08625.

    Family and domain databases

    InterProiIPR010294. ADAM_spacer1.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF05986. ADAM_spacer1. 1 hit.
    PF00090. TSP_1. 2 hits.
    [Graphical view]
    PRINTSiPR01857. ADAMTSFAMILY.
    SMARTiSM00209. TSP1. 3 hits.
    [Graphical view]
    SUPFAMiSSF82895. SSF82895. 3 hits.
    PROSITEiPS50092. TSP1. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6ZN14-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGPTSVLRAG LTPSCLPPPS GATNGSVSPL GRAQRVWTEP GGRGLHGATA    50
    AGPVAAACPL LAVTATAPGQ PSGASTVWVR EGGTAPATRM TVPLAPRTSE 100
    KCSVLNLTAS LSVGNSTSGK RTGEACSLTC LAEGFNFYTE RAAAVVDGTP 150
    CRPDTVDICV SGECKHVGCD RVLGSDLRED KCRVCGGDGS ACETIEGVFS 200
    PASPGAGYED VVWIPKGSVH IFIQDLNLSL NHLALKGDQE SLLLEGLPGT 250
    PQPHRLPLAG TTFQLRQGPD QVQSLEALGP INASLIVMVL ARTELPALRY 300
    RFNAPIARDS LPPYSWHYAP WTRCSAQCAG GSQVQAVECR NQLDGSAVAP 350
    HYCSAHSKLP KRQRACNTEP CPPDWVVGNW SLCSRSCDAG VRSRSVVCQR 400
    RVSAAEEKAL DDSACPQPRP PVLEACHGPT CPPEWAALDW SECTPSCGPG 450
    LRHRVVLCKS ADHRATLPPA HCSPAAKPPA TMRCNLRRCP PAR 493
    Length:493
    Mass (Da):51,830
    Last modified:July 5, 2004 - v1
    Checksum:i537BBDABE7D13009
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK131414 mRNA. Translation: BAD18561.1.
    RefSeqiNP_001269281.1. NM_001282352.1.
    NP_112219.3. NM_030957.3.
    UniGeneiHs.657508.

    Genome annotation databases

    GeneIDi81794.
    KEGGihsa:81794.
    UCSCiuc002mki.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK131414 mRNA. Translation: BAD18561.1 .
    RefSeqi NP_001269281.1. NM_001282352.1.
    NP_112219.3. NM_030957.3.
    UniGenei Hs.657508.

    3D structure databases

    ProteinModelPortali Q6ZN14.
    ModBasei Search...

    Protein family/group databases

    MEROPSi M12.235.

    Proteomic databases

    PRIDEi Q6ZN14.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 81794.
    KEGGi hsa:81794.
    UCSCi uc002mki.1. human.

    Organism-specific databases

    CTDi 81794.
    PharmGKBi PA24537.

    Phylogenomic databases

    HOGENOMi HOG000203663.
    KOi K08625.

    Miscellaneous databases

    GenomeRNAii 81794.
    NextBioi 72110.

    Family and domain databases

    InterProi IPR010294. ADAM_spacer1.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF05986. ADAM_spacer1. 1 hit.
    PF00090. TSP_1. 2 hits.
    [Graphical view ]
    PRINTSi PR01857. ADAMTSFAMILY.
    SMARTi SM00209. TSP1. 3 hits.
    [Graphical view ]
    SUPFAMi SSF82895. SSF82895. 3 hits.
    PROSITEi PS50092. TSP1. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ6ZN14_HUMAN
    AccessioniPrimary (citable) accession number: Q6ZN14
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: April 16, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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