Reviewed, UniProtKB/Swiss-Prot Q6ZN03 (CU136_HUMAN)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein C21orf136

Gene names

Name:

C21orf136

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Uncharacterized protein C21orf136		PRO_0000311264
Amino acid modifications
	Modified residue	165	1	Phosphoserine Ref.2
	Modified residue	166	1	Phosphoserine Ref.2
	Modified residue	167	1	Phosphoserine Ref.2
	Modified residue	179	1	Phosphothreonine Ref.2
Natural variations
	Natural variant	116	1	L → F: dbSNP rs564352.		VAR_050931
	Natural variant	149	1	A → T: dbSNP rs2838262.		VAR_050932

Sequences

	Sequence		Length	Mass (Da)
	Q6ZN03-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B21AD348C60AA8CF	FASTA	302	32,374
	10 20 30 40 50 60 MALLITPAGV ATVNRHSTIP SDTHTSREKP RFHKPCRNDL ESLLSEGRLD TSVQTPCPQH 70 80 90 100 110 120 PHTQLSCEPQ PLEHSSCLST CLAGCFLPVP SSPHTHPLLP GSRWLPPPLA LLMGTLSPGL 130 140 150 160 170 180 AVKPSWVPRF PLLARQSPAT SVGMPLSAAT QPGSVGRLHF PKLRSSSPFS GHSDENKATG 190 200 210 220 230 240 QGRENRDQPQ RPSHLCECPE AAKQSATNGV AETNRSVFPL GSEARSLSLR RQESQPHSGS 250 260 270 280 290 300 SRRESVSCSP SFWCCWQPLA FLTCGCAAPI SVPGVTRPSP RPCCVSPPLV RLQSLGLGPT QI

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.

[2]

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed: 17081983] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-165; SER-166; SER-167 AND THR-179, MASS SPECTROMETRY. Tissue: Epithelium.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK131425 mRNA. Translation: BAD18572.1.
IPI	IPI00442033.
UniGene	Hs.473952
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	Q6ZN03.
Proteomic databases
PRIDE	Q6ZN03.
Genome annotation databases
Ensembl	ENST00000450517; ENSP00000407712; ENSG00000228761; Homo sapiens. [Genome view]
Organism-specific databases
GeneCards	GC21M043574.
HGNC	HGNC:33698. C21orf136.
GenAtlas	Search...
Gene expression databases
Bgee	Q6ZN03.
CleanEx	HS_C21orf136.
Genevestigator	Q6ZN03.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CU136_HUMAN

Accession

Primary (citable) accession number: Q6ZN03

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 13, 2007
Last sequence update:	July 5, 2004
Last modified:	November 24, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.