SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6ZMS4

- ZN852_HUMAN

UniProt

Q6ZMS4 - ZN852_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Putative zinc finger protein 852
Gene
ZNF852
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri117 – 13923C2H2-type 1
Add
BLAST
Zinc fingeri145 – 16723C2H2-type 2
Add
BLAST
Zinc fingeri173 – 19523C2H2-type 3
Add
BLAST
Zinc fingeri201 – 22323C2H2-type 4
Add
BLAST
Zinc fingeri229 – 25123C2H2-type 5
Add
BLAST
Zinc fingeri257 – 27923C2H2-type 6
Add
BLAST
Zinc fingeri285 – 30723C2H2-type 7
Add
BLAST
Zinc fingeri313 – 33523C2H2-type 8
Add
BLAST
Zinc fingeri341 – 36323C2H2-type 9
Add
BLAST
Zinc fingeri369 – 39123C2H2-type 10
Add
BLAST
Zinc fingeri397 – 41923C2H2-type 11
Add
BLAST
Zinc fingeri425 – 44723C2H2-type 12
Add
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative zinc finger protein 852
Gene namesi
Name:ZNF852
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:27713. ZNF852.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 509509Putative zinc finger protein 852
PRO_0000332125Add
BLAST

Proteomic databases

PaxDbiQ6ZMS4.
PRIDEiQ6ZMS4.

PTM databases

PhosphoSiteiQ6ZMS4.

Expressioni

Gene expression databases

BgeeiQ6ZMS4.
GenevestigatoriQ6ZMS4.

Organism-specific databases

HPAiHPA048312.
HPA049885.

Structurei

3D structure databases

ProteinModelPortaliQ6ZMS4.
SMRiQ6ZMS4. Positions 96-489.

Family & Domainsi

Sequence similaritiesi

Contains 12 C2H2-type zinc fingers.

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG5048.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
OrthoDBiEOG7KSX7Q.
PhylomeDBiQ6ZMS4.
TreeFamiTF350837.

Family and domain databases

Gene3Di3.30.160.60. 12 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 12 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 12 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6ZMS4-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MMLENDRSMA SLAGRNMMES SELTPKQEIF KGSESSNSTS GGLFGVVPGG    50
TETGDVCEDT FKELEGQPSN EEGSRLESDF LEIIDEDKKK STKDRYEEYK 100
EVEEHPPLSS SPVEHEGVLK GQKSYRCDEC GKAFYWSSHL IGHRRIHTGE 150
KPYECNECGK TFRQTSQLIV HLRTHTGEKP YECSECGKAY RHSSHLIQHQ 200
RLHNGEKPYK CNECAKAFNQ SSKLFDHQRT HTGEKPYECK ECGAAFSRSK 250
NLVRHQFLHT GKKPYKCNEC GRAFCSNRNL IDHQRTHTGE KPYKCNECGK 300
AFSRSKCLIR HQSLHTGEKP YKCSECGKAF NQISQLVEHE RIHTGEKPFK 350
CSECGKAFGL SKCLIRHQRL HTSEKPYKCN ECGKSFNQNS YLIIHQRIHT 400
GEKPYECNEC GKVFSYNSSL MVHQRTHTGE KPYKCNSCGK AFSDSSQLTV 450
HQRVHTGEKN LMNVLSVGKP LVSVPLLITT SELMLERSPQ VWLGHLLKAW 500
FSETDSKDL 509
Length:509
Mass (Da):57,994
Last modified:June 15, 2010 - v3
Checksum:i69EB82FC9E8900D0
GO
Isoform 2 (identifier: Q6ZMS4-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-16: Missing.

Note: No experimental confirmation available.

Show »
Length:493
Mass (Da):56,216
Checksum:i89C5E2FF31D221AC
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 1616Missing in isoform 2.
VSP_039373Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC099669 Genomic DNA. No translation available.
BC014381 mRNA. No translation available.
AK131507 mRNA. No translation available.
UniGeneiHs.648974.

Genome annotation databases

EnsembliENST00000436261; ENSP00000389841; ENSG00000178917.
UCSCiuc011azx.2. human. [Q6ZMS4-2]
uc011azy.2. human. [Q6ZMS4-1]

Polymorphism databases

DMDMi298286894.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC099669 Genomic DNA. No translation available.
BC014381 mRNA. No translation available.
AK131507 mRNA. No translation available.
UniGenei Hs.648974.

3D structure databases

ProteinModelPortali Q6ZMS4.
SMRi Q6ZMS4. Positions 96-489.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q6ZMS4.

Polymorphism databases

DMDMi 298286894.

Proteomic databases

PaxDbi Q6ZMS4.
PRIDEi Q6ZMS4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000436261 ; ENSP00000389841 ; ENSG00000178917 .
UCSCi uc011azx.2. human. [Q6ZMS4-2 ]
uc011azy.2. human. [Q6ZMS4-1 ]

Organism-specific databases

GeneCardsi GC03M044517.
HGNCi HGNC:27713. ZNF852.
HPAi HPA048312.
HPA049885.
neXtProti NX_Q6ZMS4.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5048.
HOGENOMi HOG000234617.
HOVERGENi HBG018163.
OrthoDBi EOG7KSX7Q.
PhylomeDBi Q6ZMS4.
TreeFami TF350837.

Gene expression databases

Bgeei Q6ZMS4.
Genevestigatori Q6ZMS4.

Family and domain databases

Gene3Di 3.30.160.60. 12 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 12 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 12 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-384 (ISOFORM 1).
    Tissue: Melanoma.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-366 (ISOFORM 2).
    Tissue: Uterus.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.

Entry informationi

Entry nameiZN852_HUMAN
AccessioniPrimary (citable) accession number: Q6ZMS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: June 15, 2010
Last modified: June 11, 2014
This is version 81 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi