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Q6ZMQ8

- LMTK1_HUMAN

UniProt

Q6ZMQ8 - LMTK1_HUMAN

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Protein
Serine/threonine-protein kinase LMTK1
Gene
AATK, AATYK, KIAA0641, LMR1, LMTK1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

May be involved in neuronal differentiation.1 Publication

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei156 – 1561ATP By similarity
Active sitei253 – 2531Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi131 – 1399ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein binding Source: IntAct
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
  4. protein tyrosine kinase activity Source: Ensembl

GO - Biological processi

  1. Rab protein signal transduction Source: Ensembl
  2. brain development Source: Ensembl
  3. negative regulation of axon extension Source: Ensembl
  4. neuron apoptotic process Source: Ensembl
  5. peptidyl-tyrosine autophosphorylation Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ6ZMQ8.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase LMTK1 (EC:2.7.11.1)
Alternative name(s):
Apoptosis-associated tyrosine kinase
Short name:
AATYK
Brain apoptosis-associated tyrosine kinase
CDK5-binding protein
Lemur tyrosine kinase 1
p35-binding protein
Short name:
p35BP
Gene namesi
Name:AATK
Synonyms:AATYK, KIAA0641, LMR1, LMTK1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:21. AATK.

Subcellular locationi

Membrane; Single-pass type I membrane protein By similarity. Cytoplasm. Cytoplasmperinuclear region
Note: Predominantly perinuclear.1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei32 – 5221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. axonal growth cone Source: Ensembl
  2. endoplasmic reticulum Source: Ensembl
  3. integral component of membrane Source: UniProtKB-KW
  4. perinuclear region of cytoplasm Source: UniProtKB-SubCell
  5. recycling endosome Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24370.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13741374Serine/threonine-protein kinase LMTK1
PRO_0000248300Add
BLAST

Post-translational modificationi

Autophosphorylated. Phosphorylated by CDK5.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ6ZMQ8.
PaxDbiQ6ZMQ8.
PRIDEiQ6ZMQ8.

PTM databases

PhosphoSiteiQ6ZMQ8.

Expressioni

Tissue specificityi

Expressed in brain.1 Publication

Inductioni

Up-regulated during apoptosis.

Gene expression databases

ArrayExpressiQ6ZMQ8.
BgeeiQ6ZMQ8.
CleanExiHS_AATK.
GenevestigatoriQ6ZMQ8.

Organism-specific databases

HPAiHPA009073.

Interactioni

Subunit structurei

Interacts with CDK5.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
CDK5R1Q150786EBI-2008441,EBI-746189

Protein-protein interaction databases

BioGridi114984. 3 interactions.
IntActiQ6ZMQ8. 5 interactions.
STRINGi9606.ENSP00000324196.

Structurei

3D structure databases

ProteinModelPortaliQ6ZMQ8.
SMRiQ6ZMQ8. Positions 119-395.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini125 – 395271Protein kinase
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi420 – 42910Poly-Gly
Compositional biasi709 – 829121Pro-rich
Add
BLAST
Compositional biasi847 – 8504Poly-Ser
Compositional biasi1052 – 1151100Pro-rich
Add
BLAST
Compositional biasi1159 – 11635Poly-Glu

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000049266.
HOVERGENiHBG080533.
InParanoidiQ6ZMQ8.
KOiK17480.
OMAiCPPFFED.
OrthoDBiEOG7MH0XB.
PhylomeDBiQ6ZMQ8.
TreeFamiTF332280.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6ZMQ8-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSSSFFNPSF AFSSHFDPDG APLSELSWPS SLAVVAVSFS GLFAVIVLML     50
ACLCCKKGGI GFKEFENAEG DEYAADLAQG SPATAAQNGP DVYVLPLTEV 100
SLPMAKQPGR SVQLLKSTDV GRHSLLYLKE IGRGWFGKVF LGEVNSGISS 150
AQVVVKELQA SASVQEQMQF LEEVQPYRAL KHSNLLQCLA QCAEVTPYLL 200
VMEFCPLGDL KGYLRSCRVA ESMAPDPRTL QRMACEVACG VLHLHRNNFV 250
HSDLALRNCL LTADLTVKIG DYGLAHCKYR EDYFVTADQL WVPLRWIAPE 300
LVDEVHSNLL VVDQTKSGNV WSLGVTIWEL FELGTQPYPQ HSDQQVLAYT 350
VREQQLKLPK PQLQLTLSDR WYEVMQFCWL QPEQRPTAEE VHLLLSYLCA 400
KGATEAEEEF ERRWRSLRPG GGGVGPGPGA AGPMLGGVVE LAAASSFPLL 450
EQFAGDGFHA DGDDVLTVTE TSRGLNFEYK WEAGRGAEAF PATLSPGRTA 500
RLQELCAPDG APPGVVPVLS AHSPSLGSEY FIRLEEAAPA AGHDPDCAGC 550
APSPPATADQ DDDSDGSTAA SLAMEPLLGH GPPVDVPWGR GDHYPRRSLA 600
RDPLCPSRSP SPSAGPLSLA EGGAEDADWG VAAFCPAFFE DPLGTSPLGS 650
SGAPPLPLTG EDELEEVGAR RAAQRGHWRS NVSANNNSGS RCPESWDPVS 700
AGGHAEGCPS PKQTPRASPE PGYPGEPLLG LQAASAQEPG CCPGLPHLCS 750
AQGLAPAPCL VTPSWTETAS SGGDHPQAEP KLATEAEGTT GPRLPLPSVP 800
SPSQEGAPLP SEEASAPDAP DALPDSPTPA TGGEVSAIKL ASALNGSSSS 850
PEVEAPSSED EDTAEATSGI FTDTSSDGLQ ARRPDVVPAF RSLQKQVGTP 900
DSLDSLDIPS SASDGGYEVF SPSATGPSGG QPRALDSGYD TENYESPEFV 950
LKEAQEGCEP QAFAELASEG EGPGPETRLS TSLSGLNEKN PYRDSAYFSD 1000
LEAEAEATSG PEKKCGGDRA PGPELGLPST GQPSEQVCLR PGVSGEAQGS 1050
GPGEVLPPLL QLEGSSPEPS TCPSGLVPEP PEPQGPAKVR PGPSPSCSQF 1100
FLLTPVPLRS EGNSSEFQGP PGLLSGPAPQ KRMGGPGTPR APLRLALPGL 1150
PAALEGRPEE EEEDSEDSDE SDEELRCYSV QEPSEDSEEE APAVPVVVAE 1200
SQSARNLRSL LKMPSLLSET FCEDLERKKK AVSFFDDVTV YLFDQESPTR 1250
ELGEPFPGAK ESPPTFLRGS PGSPSAPNRP QQADGSPNGS TAEEGGGFAW 1300
DDDFPLMTAK AAFAMALDPA APAPAAPTPT PAPFSRFTVS PAPTSRFSIT 1350
HVSDSDAESK RGPEAGAGGE SKEA 1374
Length:1,374
Mass (Da):144,569
Last modified:September 5, 2006 - v2
Checksum:iAD46BD688AF7103E
GO
Isoform 2 (identifier: Q6ZMQ8-2) [UniParc]FASTAAdd to Basket

Also known as: hAATYKs-p35BP

The sequence of this isoform differs from the canonical sequence as follows:
     1-433: Missing.
     468-503: Missing.
     897-915: VGTPDSLDSLDIPSSASDG → WPQREESLPRLCLLLRPRG
     916-1374: Missing.

Show »
Length:446
Mass (Da):45,358
Checksum:i38EA067D9AA55653
GO
Isoform 3 (identifier: Q6ZMQ8-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     468-503: Missing.
     897-915: VGTPDSLDSLDIPSSASDG → WPQREESLPRLCLLLRPRG
     916-1374: Missing.

Show »
Length:879
Mass (Da):93,226
Checksum:iB31470ED8B3E5E78
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti81 – 811S → F in an ovarian mucinous carcinoma sample; somatic mutation. 1 Publication
VAR_032679
Natural varianti97 – 971L → V in a lung adenocarcinoma sample; somatic mutation. 1 Publication
VAR_032680
Natural varianti104 – 1041M → V in an ovarian mucinous carcinoma sample; somatic mutation. 1 Publication
VAR_032681
Natural varianti118 – 1181T → M.
Corresponds to variant rs8082016 [ dbSNP | Ensembl ].
VAR_027267
Natural varianti703 – 7031G → C.3 Publications
Corresponds to variant rs7503604 [ dbSNP | Ensembl ].
VAR_032682
Natural varianti815 – 8151S → R.1 Publication
Corresponds to variant rs56032966 [ dbSNP | Ensembl ].
VAR_032683
Natural varianti923 – 9231S → L.1 Publication
Corresponds to variant rs56313973 [ dbSNP | Ensembl ].
VAR_032684
Natural varianti1160 – 11601E → K.1 Publication
Corresponds to variant rs55793641 [ dbSNP | Ensembl ].
VAR_032685
Natural varianti1192 – 11921P → S.1 Publication
Corresponds to variant rs55856613 [ dbSNP | Ensembl ].
VAR_032686
Natural varianti1266 – 12661F → S.2 Publications
Corresponds to variant rs36000545 [ dbSNP | Ensembl ].
VAR_032687
Natural varianti1332 – 13321A → T.1 Publication
Corresponds to variant rs55713566 [ dbSNP | Ensembl ].
VAR_032688

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 433433Missing in isoform 2.
VSP_020225Add
BLAST
Alternative sequencei468 – 50336Missing in isoform 2 and isoform 3.
VSP_020226Add
BLAST
Alternative sequencei897 – 91519VGTPD…SASDG → WPQREESLPRLCLLLRPRG in isoform 2 and isoform 3.
VSP_020227Add
BLAST
Alternative sequencei916 – 1374459Missing in isoform 2 and isoform 3.
VSP_020228Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti49 – 6315MLACL…GIGFK → HQVKVQGCWGRWRWQ1 Publication
Add
BLAST
Sequence conflicti511 – 5111A → T in BAD18667. 1 Publication
Sequence conflicti541 – 5411A → T in BAD18544. 1 Publication
Sequence conflicti557 – 5571T → I in BAD18544. 1 Publication
Sequence conflicti786 – 7861A → V in AAH47378. 1 Publication
Sequence conflicti790 – 7901T → A in BAD18667. 1 Publication
Sequence conflicti1028 – 10281P → R in AAH47378. 1 Publication
Sequence conflicti1271 – 12711P → H in AAH47378. 1 Publication
Sequence conflicti1324 – 13241P → R in AAH47378. 1 Publication
Sequence conflicti1360 – 13601K → E in AAH47378. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK131395 mRNA. Translation: BAD18544.1.
AK131529 mRNA. Translation: BAD18667.1.
AB014541 mRNA. Translation: BAA31616.2.
BC047378 mRNA. Translation: AAH47378.1.
CCDSiCCDS45807.1. [Q6ZMQ8-1]
RefSeqiNP_001073864.2. NM_001080395.2. [Q6ZMQ8-1]
NP_004911.2. NM_004920.2.
UniGeneiHs.514575.

Genome annotation databases

EnsembliENST00000326724; ENSP00000324196; ENSG00000181409. [Q6ZMQ8-1]
ENST00000374792; ENSP00000363924; ENSG00000181409. [Q6ZMQ8-3]
GeneIDi9625.
KEGGihsa:9625.
UCSCiuc010dia.3. human. [Q6ZMQ8-1]

Polymorphism databases

DMDMi114149222.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

CGP resequencing studies

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK131395 mRNA. Translation: BAD18544.1 .
AK131529 mRNA. Translation: BAD18667.1 .
AB014541 mRNA. Translation: BAA31616.2 .
BC047378 mRNA. Translation: AAH47378.1 .
CCDSi CCDS45807.1. [Q6ZMQ8-1 ]
RefSeqi NP_001073864.2. NM_001080395.2. [Q6ZMQ8-1 ]
NP_004911.2. NM_004920.2.
UniGenei Hs.514575.

3D structure databases

ProteinModelPortali Q6ZMQ8.
SMRi Q6ZMQ8. Positions 119-395.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 114984. 3 interactions.
IntActi Q6ZMQ8. 5 interactions.
STRINGi 9606.ENSP00000324196.

PTM databases

PhosphoSitei Q6ZMQ8.

Polymorphism databases

DMDMi 114149222.

Proteomic databases

MaxQBi Q6ZMQ8.
PaxDbi Q6ZMQ8.
PRIDEi Q6ZMQ8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000326724 ; ENSP00000324196 ; ENSG00000181409 . [Q6ZMQ8-1 ]
ENST00000374792 ; ENSP00000363924 ; ENSG00000181409 . [Q6ZMQ8-3 ]
GeneIDi 9625.
KEGGi hsa:9625.
UCSCi uc010dia.3. human. [Q6ZMQ8-1 ]

Organism-specific databases

CTDi 9625.
GeneCardsi GC17M079091.
HGNCi HGNC:21. AATK.
HPAi HPA009073.
MIMi 605276. gene.
neXtProti NX_Q6ZMQ8.
PharmGKBi PA24370.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000049266.
HOVERGENi HBG080533.
InParanoidi Q6ZMQ8.
KOi K17480.
OMAi CPPFFED.
OrthoDBi EOG7MH0XB.
PhylomeDBi Q6ZMQ8.
TreeFami TF332280.

Enzyme and pathway databases

SignaLinki Q6ZMQ8.

Miscellaneous databases

GeneWikii AATK.
GenomeRNAii 9625.
NextBioi 36117.
PROi Q6ZMQ8.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q6ZMQ8.
Bgeei Q6ZMQ8.
CleanExi HS_AATK.
Genevestigatori Q6ZMQ8.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view ]
Pfami PF07714. Pkinase_Tyr. 1 hit.
[Graphical view ]
PRINTSi PR00109. TYRKINASE.
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3), VARIANT CYS-703.
    Tissue: Cerebellum and Thalamus.
  2. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Ishikawa K., Nagase T., Suyama M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 49-1374 (ISOFORM 1), VARIANT CYS-703.
    Tissue: Brain.
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 786-1374 (ISOFORM 1), VARIANT SER-1266.
    Tissue: Brain.
  5. Cited for: ALTERNATIVE SPLICING (ISOFORM 2), INTERACTION WITH CDK5, PHOSPHORYLATION.
  6. "A novel kinase, AATYK induces and promotes neuronal differentiation in a human neuroblastoma (SH-SY5Y) cell line."
    Raghunath M., Patti R., Bannerman P., Lee C.M., Baker S., Sutton L.N., Phillips P.C., Damodar Reddy C.
    Brain Res. Mol. Brain Res. 77:151-162(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY, SUBCELLULAR LOCATION, FUNCTION.
  7. "Patterns of somatic mutation in human cancer genomes."
    Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S., O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S., Bhamra G., Buck G.
    , Choudhury B., Clements J., Cole J., Dicks E., Forbes S., Gray K., Halliday K., Harrison R., Hills K., Hinton J., Jenkinson A., Jones D., Menzies A., Mironenko T., Perry J., Raine K., Richardson D., Shepherd R., Small A., Tofts C., Varian J., Webb T., West S., Widaa S., Yates A., Cahill D.P., Louis D.N., Goldstraw P., Nicholson A.G., Brasseur F., Looijenga L., Weber B.L., Chiew Y.-E., DeFazio A., Greaves M.F., Green A.R., Campbell P., Birney E., Easton D.F., Chenevix-Trench G., Tan M.-H., Khoo S.K., Teh B.T., Yuen S.T., Leung S.Y., Wooster R., Futreal P.A., Stratton M.R.
    Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS PHE-81; VAL-97; VAL-104; CYS-703; ARG-815; LEU-923; LYS-1160; SER-1192; SER-1266 AND THR-1332.

Entry informationi

Entry nameiLMTK1_HUMAN
AccessioniPrimary (citable) accession number: Q6ZMQ8
Secondary accession number(s): O75136, Q6ZN31, Q86X28
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: July 9, 2014
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human and mouse protein kinases
    Human and mouse protein kinases: classification and index
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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