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Protein
Submitted name:

cDNA FLJ23935 fis, clone COLF0858

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: InterPro

GO - Biological processi

  1. neuropeptide signaling pathway Source: InterPro
Complete GO annotation...

Protein family/group databases

MEROPSiS63.023.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ23935 fis, clone COLF0858Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiQ6ZMH0.
ExpressionAtlasiQ6ZMH0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ6ZMH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains GPS domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG063831.

Family and domain databases

InterProiIPR017981. GPCR_2-like.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZMH0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVFSPKYNQK EFQLYSYACV YWNLSAKDWD TYGCQKDKGT DGFLRCRCNH
60 70 80 90 100
TTNFAVLMTF KKDYQYPKSL DILSNVGCAL SVTGLALTVI FQIVTRKVRK
110 120 130 140 150
TSVTWVLVNL CISMLIFNLL FVFGIENSNK NLQTSDGDIN NIDFDNNDIP
160 170 180 190 200
RTDTINIPNP MCTAIAALLH YFLLVTFTWN ALSAAQLYYL LIRTMKPLPR
210 220 230 240 250
HFILFISLIG WGVPAIVVAI TVGVIYSQNG NNPQWELDYR QEKICWLAIP
260 270 280 290 300
EPNGVIKSPL LWSFIVPVTI ILISNVVMFI TISIKVLWKN NQNLTSTKKV
310 320 330 340 350
SSMKKIVSTL SVAVVFGITW ILAYLMLVND DSIRIVFSYI FCLFNTTQGL
360 370 380 390 400
QIFILYTVRT KVFQSEASKV LMLLSSIGRR KSLPSVTRPR LRVKMYNFLR
410 420 430
SLPTLHERFR LLETSPSTEE ITLSESDNAK ESI
Length:433
Mass (Da):49,445
Last modified:July 5, 2004 - v1
Checksum:iC8E13FF2E01525A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK172774 mRNA. Translation: BAD18756.1.
UniGeneiHs.334511.

Genome annotation databases

UCSCiuc003dud.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK172774 mRNA. Translation: BAD18756.1.
UniGeneiHs.334511.

3D structure databases

ProteinModelPortaliQ6ZMH0.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS63.023.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc003dud.3. human.

Phylogenomic databases

HOVERGENiHBG063831.

Gene expression databases

BgeeiQ6ZMH0.
ExpressionAtlasiQ6ZMH0. baseline and differential.

Family and domain databases

InterProiIPR017981. GPCR_2-like.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project."
    Watanabe K., Kumagai A., Itakura S., Yamazaki M., Tashiro H., Ota T., Suzuki Y., Obayashi M., Nishi T., Shibahara T., Tanaka T., Nakamura Y., Isogai T., Sugano S.
    Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Colon mucosaImported.

Entry informationi

Entry nameiQ6ZMH0_HUMAN
AccessioniPrimary (citable) accession number: Q6ZMH0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 4, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.