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Protein

Delphilin

Gene

grid2ip

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Postsynaptic scaffolding protein.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Delphilin
Alternative name(s):
Glutamate receptor, ionotropic, delta 2-interacting protein 1
Gene namesi
Name:grid2ip
ORF Names:si:ch211-147h1.3
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 12

Organism-specific databases

ZFINiZDB-GENE-040724-161. grid2ipb.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003316261 – 1009DelphilinAdd BLAST1009

Proteomic databases

PaxDbiQ6ZM86.

Expressioni

Gene expression databases

BgeeiENSDARG00000095603.
ExpressionAtlasiQ6ZM86. baseline.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000116904.

Structurei

3D structure databases

ProteinModelPortaliQ6ZM86.
SMRiQ6ZM86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini95 – 172PDZPROSITE-ProRule annotationAdd BLAST78
Domaini629 – 1009FH2PROSITE-ProRule annotationAdd BLAST381

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi416 – 438Ser-richAdd BLAST23
Compositional biasi442 – 629Pro-richAdd BLAST188

Phylogenomic databases

eggNOGiKOG1922. Eukaryota.
KOG3589. Eukaryota.
ENOG410ZNSD. LUCA.
GeneTreeiENSGT00760000118986.
InParanoidiQ6ZM86.
PhylomeDBiQ6ZM86.
TreeFamiTF329416.

Family and domain databases

InterProiView protein in InterPro
IPR015425. FH2_Formin.
IPR001478. PDZ.
PfamiView protein in Pfam
PF02181. FH2. 1 hit.
PF00595. PDZ. 1 hit.
SMARTiView protein in SMART
SM00498. FH2. 1 hit.
SM00228. PDZ. 1 hit.
SUPFAMiSSF50156. SSF50156. 1 hit.
PROSITEiView protein in PROSITE
PS51444. FH2. 1 hit.
PS50106. PDZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6ZM86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFARIFIPKK HRQRFDEAVS QSLINRMCRS KSLGEPQNRL RRSRSQDHHE
60 70 80 90 100
RPQGSKRASS VPRDTGDEPA QNDRTLRKSN TMIPTQYVSG VNQRTIRVYR
110 120 130 140 150
GKKSFGFTLR GHAPVWIDSV MPGSPAEACG LKTGDRILFL NGLDMRNCSH
160 170 180 190 200
EKVVSMLQGS GAMPSLVVEE GPVDYPQSDS EPEETPSAPR SRSPALSSLQ
210 220 230 240 250
WVAEILPPSI RVHGRTFSQQ LEHLLTLQER YTICKALETF FQHRNVDTLI
260 270 280 290 300
VDVFPVLDTP AKQLIWQFIY QLLTYEEQEH CKTKIARFLG FKSAGNRKSG
310 320 330 340 350
LSLTWTDSFP GPQFETYQQT VASPDSVDSN PYVSLDSPPA SPLPSDELSP
360 370 380 390 400
LPQRRKLFTF SRPPRSRDTD KFLDALSEQL GHRVNIVDDF KGGENDYEEM
410 420 430 440 450
SFQDEQEVNM LPHELSSASS EDHSSSDDST SVSYSSGSDH IPPPPQSPPP
460 470 480 490 500
PPPPLQFTDS PSPLPITPEH LPQPPPAFQH HPIIAPPPPP PRPFLANRPS
510 520 530 540 550
LHKVLPTREE LRAQHSHPRR SSPQPSSQPI LQLHQPKAHP ILQSSPHTSP
560 570 580 590 600
QPPHTSAQHT RLQHPSQSIY QSQQTTVPRT SPSLTKQKSL HSQPSQQSFE
610 620 630 640 650
GTLSSKVPPP PPPPLPPPCD PPPLPKPSPK ASDNNHMSVK RLRWEQLGDD
660 670 680 690 700
PDYHKLSDMV KYLDLDLYFG TQRNSKPTFL PENLKKKDVV EILSHKKAYN
710 720 730 740 750
ASILIAHLKL APKELRDILM TMSTERLEPA HIKQLLLYAP DDEEVKQFQH
760 770 780 790 800
YDQDPAKLSE PDQFVLQMLL VPEYKTRLRS LLFKTTVQEK TEEMRAAYEC
810 820 830 840 850
IYKASLELKN SKRLAKILEF VLAMGNYLNN GQPKTNKTTG FKINFLTELN
860 870 880 890 900
TTKTVDGKST FLHILAKSLC QHFPELLGFS RDLITVPLAA KVNQRTITAD
910 920 930 940 950
LSDVHSTIQD IRTACVKIPA TAEDRFAAVM SSFLENCHPA VQSLDSLQQR
960 970 980 990 1000
AMDEFHKVAS YFGEDSKVTT TETFFGIFAE FISKFERALS ETQGTENPKS

PRIASPLAW
Length:1,009
Mass (Da):113,629
Last modified:July 5, 2004 - v1
Checksum:i2836245DF69B12D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772266 Genomic DNA. Translation: CAE49895.1.
RefSeqiNP_001038368.1. NM_001044903.1.
UniGeneiDr.74085.

Genome annotation databases

EnsembliENSDART00000161128; ENSDARP00000133025; ENSDARG00000095603.
GeneIDi559717.
KEGGidre:559717.

Similar proteinsi

Entry informationi

Entry nameiGRD2I_DANRE
AccessioniPrimary (citable) accession number: Q6ZM86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome