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Q6ZDY8

- SDHA_ORYSJ

UniProt

Q6ZDY8 - SDHA_ORYSJ

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Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

SDH1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).By similarity

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.

Cofactori

FAD.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei260 – 2601FADBy similarity
Binding sitei281 – 2811SubstrateBy similarity
Binding sitei293 – 2931SubstrateBy similarity
Active sitei325 – 3251Proton acceptorBy similarity
Binding sitei392 – 3921SubstrateBy similarity
Binding sitei426 – 4261FADBy similarity
Binding sitei437 – 4371SubstrateBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi52 – 576FADBy similarity
Nucleotide bindingi75 – 9016FADBy similarityAdd
BLAST
Nucleotide bindingi442 – 4432FADBy similarity

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: InterPro
  2. succinate dehydrogenase (ubiquinone) activity Source: UniProtKB-EC

GO - Biological processi

  1. electron transport chain Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Transport, Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01006.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC:1.3.5.1)
Alternative name(s):
Flavoprotein subunit of complex II
Short name:
FP
Gene namesi
Name:SDH1
Ordered Locus Names:Os07g0134800, LOC_Os07g04240
ORF Names:P0507H12.27
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 7

Organism-specific databases

GrameneiQ6ZDY8.

Subcellular locationi

Mitochondrion inner membrane By similarity; Peripheral membrane protein By similarity; Matrix side By similarity

GO - Cellular componenti

  1. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3131MitochondrionSequence AnalysisAdd
BLAST
Chaini32 – 630599Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialPRO_0000247593Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei83 – 831Tele-8alpha-FAD histidineBy similarity

Proteomic databases

PaxDbiQ6ZDY8.
PRIDEiQ6ZDY8.

Expressioni

Gene expression databases

ExpressionAtlasiQ6ZDY8. baseline and differential.

Interactioni

Subunit structurei

Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ6ZDY8.
SMRiQ6ZDY8. Positions 36-630.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG1053.
HOGENOMiHOG000160475.
InParanoidiQ6ZDY8.
KOiK00234.
OMAiRDGPILQ.

Family and domain databases

Gene3Di1.20.58.100. 1 hit.
3.90.700.10. 1 hit.
InterProiIPR003953. FAD_bind_dom.
IPR003952. FRD_SDH_FAD_BS.
IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
IPR027477. Succ_DH/fumarate_Rdtase_cat.
IPR011281. Succ_DH_flav_su_fwd.
IPR014006. Succ_Dhase_FrdA_Gneg.
[Graphical view]
PfamiPF00890. FAD_binding_2. 1 hit.
PF02910. Succ_DH_flav_C. 1 hit.
[Graphical view]
SUPFAMiSSF46977. SSF46977. 1 hit.
SSF56425. SSF56425. 1 hit.
TIGRFAMsiTIGR01816. sdhA_forward. 1 hit.
TIGR01812. sdhA_frdA_Gneg. 1 hit.
PROSITEiPS00504. FRD_SDH_FAD_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6ZDY8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWRGCVSRGL RSLSKGKGSS SSAPVSAAAR LFSTASSSYT VVDHSYDAVV
60 70 80 90 100
VGAGGAGLRA AIGLSEHGFN TACITKLFPT RSHTVAAQGG INAALGNMTE
110 120 130 140 150
DDWRWHMYDT VKGSDWLGDQ DSIQYMCREA PKAVIELENY GLPFSRTEDG
160 170 180 190 200
KIYQRAFGGQ SLDFGKGGQA YRCACAADRT GHAMLHTLYG QAMKHNTQFF
210 220 230 240 250
VEYFALDLIM DSEGTCQGVI ALNMEDGTLH RFRATNTILA TGGYGRAYFS
260 270 280 290 300
ATSAHTCTGD GNAMVARAGL PLQDLEFVQF HPTGIYGAGC LITEGSRGEG
310 320 330 340 350
GILRNSEGER FMERYAPTAK DLASRDVVSR SMTMEIREGR GVGPLKDHIY
360 370 380 390 400
LHLNHLPPEV LKERLPGISE TAAIFAGVDV TKEPIPVLPT VHYNMGGIPT
410 420 430 440 450
NYHGEVVTMK GDNPDSVVPG LMAAGEAACA SVHGANRLGA NSLLDIVVFG
460 470 480 490 500
RACANRVAET AKPGEKQKPL QKSAGEKTIA WLDKLRNANG SLPTSKIRLN
510 520 530 540 550
MQRVMQNNAA VFRTQETLEE GCKLITKAWE SYHDVKISDR SLIWNSDLIE
560 570 580 590 600
TIELENLLIN ACITMHSAEA RKESRGAHAR EDFTKRDDEQ WMKHSLGYWE
610 620 630
NEKVRLAYRP VHMNTLDSEV ESFPPKARVY
Length:630
Mass (Da):68,854
Last modified:July 5, 2004 - v1
Checksum:i9BDEE1ABC77CF08C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004338 Genomic DNA. Translation: BAC83515.1.
AK065901 mRNA. No translation available.
RefSeqiNP_001058845.1. NM_001065380.1.
UniGeneiOs.22581.

Genome annotation databases

EnsemblPlantsiOS07T0134800-01; OS07T0134800-01; OS07G0134800.
GeneIDi4342350.
KEGGiosa:4342350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004338 Genomic DNA. Translation: BAC83515.1 .
AK065901 mRNA. No translation available.
RefSeqi NP_001058845.1. NM_001065380.1.
UniGenei Os.22581.

3D structure databases

ProteinModelPortali Q6ZDY8.
SMRi Q6ZDY8. Positions 36-630.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q6ZDY8.
PRIDEi Q6ZDY8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS07T0134800-01 ; OS07T0134800-01 ; OS07G0134800 .
GeneIDi 4342350.
KEGGi osa:4342350.

Organism-specific databases

Gramenei Q6ZDY8.

Phylogenomic databases

eggNOGi COG1053.
HOGENOMi HOG000160475.
InParanoidi Q6ZDY8.
KOi K00234.
OMAi RDGPILQ.

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER01006 .

Gene expression databases

ExpressionAtlasi Q6ZDY8. baseline and differential.

Family and domain databases

Gene3Di 1.20.58.100. 1 hit.
3.90.700.10. 1 hit.
InterProi IPR003953. FAD_bind_dom.
IPR003952. FRD_SDH_FAD_BS.
IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
IPR027477. Succ_DH/fumarate_Rdtase_cat.
IPR011281. Succ_DH_flav_su_fwd.
IPR014006. Succ_Dhase_FrdA_Gneg.
[Graphical view ]
Pfami PF00890. FAD_binding_2. 1 hit.
PF02910. Succ_DH_flav_C. 1 hit.
[Graphical view ]
SUPFAMi SSF46977. SSF46977. 1 hit.
SSF56425. SSF56425. 1 hit.
TIGRFAMsi TIGR01816. sdhA_forward. 1 hit.
TIGR01812. sdhA_frdA_Gneg. 1 hit.
PROSITEi PS00504. FRD_SDH_FAD_BINDING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiSDHA_ORYSJ
AccessioniPrimary (citable) accession number: Q6ZDY8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3