Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6ZDY8

- SDHA_ORYSJ

UniProt

Q6ZDY8 - SDHA_ORYSJ

Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

SDH1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).By similarity

    Catalytic activityi

    Succinate + a quinone = fumarate + a quinol.

    Cofactori

    FAD.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei260 – 2601FADBy similarity
    Binding sitei281 – 2811SubstrateBy similarity
    Binding sitei293 – 2931SubstrateBy similarity
    Active sitei325 – 3251Proton acceptorBy similarity
    Binding sitei392 – 3921SubstrateBy similarity
    Binding sitei426 – 4261FADBy similarity
    Binding sitei437 – 4371SubstrateBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi52 – 576FADBy similarity
    Nucleotide bindingi75 – 9016FADBy similarityAdd
    BLAST
    Nucleotide bindingi442 – 4432FADBy similarity

    GO - Molecular functioni

    1. ATP binding Source: EnsemblPlants/Gramene
    2. cobalt ion binding Source: EnsemblPlants/Gramene
    3. flavin adenine dinucleotide binding Source: InterPro
    4. succinate dehydrogenase (ubiquinone) activity Source: UniProtKB-EC

    GO - Biological processi

    1. electron transport chain Source: InterPro
    2. tricarboxylic acid cycle Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Transport, Tricarboxylic acid cycle

    Keywords - Ligandi

    FAD, Flavoprotein

    Enzyme and pathway databases

    UniPathwayiUPA00223; UER01006.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC:1.3.5.1)
    Alternative name(s):
    Flavoprotein subunit of complex II
    Short name:
    FP
    Gene namesi
    Name:SDH1
    Ordered Locus Names:Os07g0134800, LOC_Os07g04240
    ORF Names:P0507H12.27
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 7

    Organism-specific databases

    GrameneiQ6ZDY8.

    Subcellular locationi

    Mitochondrion inner membrane By similarity; Peripheral membrane protein By similarity; Matrix side By similarity

    GO - Cellular componenti

    1. cell wall Source: EnsemblPlants/Gramene
    2. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 3131MitochondrionSequence AnalysisAdd
    BLAST
    Chaini32 – 630599Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialPRO_0000247593Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei83 – 831Tele-8alpha-FAD histidineBy similarity

    Proteomic databases

    PaxDbiQ6ZDY8.
    PRIDEiQ6ZDY8.

    Interactioni

    Subunit structurei

    Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ6ZDY8.
    SMRiQ6ZDY8. Positions 36-630.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiCOG1053.
    HOGENOMiHOG000160475.
    KOiK00234.
    OMAiRDGPILQ.

    Family and domain databases

    Gene3Di1.20.58.100. 1 hit.
    3.90.700.10. 1 hit.
    InterProiIPR003953. FAD_bind_dom.
    IPR003952. FRD_SDH_FAD_BS.
    IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
    IPR027477. Succ_DH/fumarate_Rdtase_cat.
    IPR011281. Succ_DH_flav_su_fwd.
    IPR014006. Succ_Dhase_FrdA_Gneg.
    [Graphical view]
    PfamiPF00890. FAD_binding_2. 1 hit.
    PF02910. Succ_DH_flav_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF46977. SSF46977. 1 hit.
    SSF56425. SSF56425. 1 hit.
    TIGRFAMsiTIGR01816. sdhA_forward. 1 hit.
    TIGR01812. sdhA_frdA_Gneg. 1 hit.
    PROSITEiPS00504. FRD_SDH_FAD_BINDING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6ZDY8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWRGCVSRGL RSLSKGKGSS SSAPVSAAAR LFSTASSSYT VVDHSYDAVV    50
    VGAGGAGLRA AIGLSEHGFN TACITKLFPT RSHTVAAQGG INAALGNMTE 100
    DDWRWHMYDT VKGSDWLGDQ DSIQYMCREA PKAVIELENY GLPFSRTEDG 150
    KIYQRAFGGQ SLDFGKGGQA YRCACAADRT GHAMLHTLYG QAMKHNTQFF 200
    VEYFALDLIM DSEGTCQGVI ALNMEDGTLH RFRATNTILA TGGYGRAYFS 250
    ATSAHTCTGD GNAMVARAGL PLQDLEFVQF HPTGIYGAGC LITEGSRGEG 300
    GILRNSEGER FMERYAPTAK DLASRDVVSR SMTMEIREGR GVGPLKDHIY 350
    LHLNHLPPEV LKERLPGISE TAAIFAGVDV TKEPIPVLPT VHYNMGGIPT 400
    NYHGEVVTMK GDNPDSVVPG LMAAGEAACA SVHGANRLGA NSLLDIVVFG 450
    RACANRVAET AKPGEKQKPL QKSAGEKTIA WLDKLRNANG SLPTSKIRLN 500
    MQRVMQNNAA VFRTQETLEE GCKLITKAWE SYHDVKISDR SLIWNSDLIE 550
    TIELENLLIN ACITMHSAEA RKESRGAHAR EDFTKRDDEQ WMKHSLGYWE 600
    NEKVRLAYRP VHMNTLDSEV ESFPPKARVY 630
    Length:630
    Mass (Da):68,854
    Last modified:July 5, 2004 - v1
    Checksum:i9BDEE1ABC77CF08C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004338 Genomic DNA. Translation: BAC83515.1.
    AK065901 mRNA. No translation available.
    RefSeqiNP_001058845.1. NM_001065380.1.
    UniGeneiOs.22581.

    Genome annotation databases

    EnsemblPlantsiOS07T0134800-01; OS07T0134800-01; OS07G0134800.
    GeneIDi4342350.
    KEGGiosa:4342350.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP004338 Genomic DNA. Translation: BAC83515.1 .
    AK065901 mRNA. No translation available.
    RefSeqi NP_001058845.1. NM_001065380.1.
    UniGenei Os.22581.

    3D structure databases

    ProteinModelPortali Q6ZDY8.
    SMRi Q6ZDY8. Positions 36-630.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q6ZDY8.
    PRIDEi Q6ZDY8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS07T0134800-01 ; OS07T0134800-01 ; OS07G0134800 .
    GeneIDi 4342350.
    KEGGi osa:4342350.

    Organism-specific databases

    Gramenei Q6ZDY8.

    Phylogenomic databases

    eggNOGi COG1053.
    HOGENOMi HOG000160475.
    KOi K00234.
    OMAi RDGPILQ.

    Enzyme and pathway databases

    UniPathwayi UPA00223 ; UER01006 .

    Family and domain databases

    Gene3Di 1.20.58.100. 1 hit.
    3.90.700.10. 1 hit.
    InterProi IPR003953. FAD_bind_dom.
    IPR003952. FRD_SDH_FAD_BS.
    IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
    IPR027477. Succ_DH/fumarate_Rdtase_cat.
    IPR011281. Succ_DH_flav_su_fwd.
    IPR014006. Succ_Dhase_FrdA_Gneg.
    [Graphical view ]
    Pfami PF00890. FAD_binding_2. 1 hit.
    PF02910. Succ_DH_flav_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46977. SSF46977. 1 hit.
    SSF56425. SSF56425. 1 hit.
    TIGRFAMsi TIGR01816. sdhA_forward. 1 hit.
    TIGR01812. sdhA_frdA_Gneg. 1 hit.
    PROSITEi PS00504. FRD_SDH_FAD_BINDING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiSDHA_ORYSJ
    AccessioniPrimary (citable) accession number: Q6ZDY8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 25, 2006
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3