Q6ZDQ1 (AGM1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoacetylglucosamine mutase
Short name=PAGM
EC=5.4.2.3

Alternative name(s):
Acetylglucosamine phosphomutase
N-acetylglucosamine-phosphate mutase

Gene names

Ordered Locus Names:	Os07g0195400, LOC_Os07g09720
ORF Names:	OJ1715_A07.21, P0589E08.4

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	562 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Interconverts GlcNAc-6-P and GlcNAc-1-P By similarity.
Catalytic activity	N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Pathway	Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	UDP-N-acetylglucosamine biosynthetic process Inferred from Biological aspect of Ancestor. Source: RefGenome carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro photoreactive repair Inferred from electronic annotation. Source: EnsemblPlants/Gramene response to UV Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Cellular_component	cytosol Inferred from Biological aspect of Ancestor. Source: RefGenome mitochondrion Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoacetylglucosamine mutase activity Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 562	562	Phosphoacetylglucosamine mutase		PRO_0000247307
Sites
	Active site	74	1	Phosphoserine intermediate By similarity
	Metal binding	74	1	Magnesium; via phosphate group By similarity
	Metal binding	291	1	Magnesium By similarity
	Metal binding	293	1	Magnesium By similarity
	Metal binding	295	1	Magnesium By similarity
Experimental info
	Sequence conflict	211	1	K → E Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q6ZDQ1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: CC80059ED8ECBC0D	FASTA	562	60,344
	10 20 30 40 50 60 MAELAAGGDQ RAALLAAATL FPPPPDGARF SYGTAGFRAE GAAMGPAVCR AGVVAALRSA 70 80 90 100 110 120 KLGGAAVGVV ITASHNPVRD NGVKIVDADG GMLSQDWEPF ADALANAPNP DALLQIVLQF 130 140 150 160 170 180 AKDEDIKLGG SHSAQVLLAR DTRPTGEYLL DVAVKGVNAV IGAVAVDMGI LTTPQLHWMV 190 200 210 220 230 240 RSKNKGLKSS ETDYFSQVID SFRCLLELVP KDKEADVINN RLIVDGANGI GGLKLEEIKA 250 260 270 280 290 300 KISGLDIHVR NSGKGEGILN ESCGADFVQK EKVVPLGFGP EDVGFRCASF DGDADRLVYF 310 320 330 340 350 360 RIVSSSDTRI DLVDGDKILS LFVLFIREQL DIINGKDNKG NEVLPTRFGV IQTAYANGAS 370 380 390 400 410 420 TDFLKNIGLE VVFTPTGVKY LHKEALKYDI GIYFEANGHG TVLFSDHFVS QLESLTSEFS 430 440 450 460 470 480 SKAAGSSQHQ AAMRLLATSQ LINQAVGDAL SGMLLVEAVL QYKGWSFQNW CDLYTDLPSR 490 500 510 520 530 540 QLKVKVQDRN SIVTTDAERR VCQPNGLQEL IDGEISNYSH GRCFVRPSGT EDVVRVYAEA 550 560 SSEEAADCLA KRVAQHVERI LG

References

[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP003848 Genomic DNA. Translation: BAD30377.1. AP004379 Genomic DNA. Translation: BAC83577.1. AK069901 mRNA. No translation available.
RefSeq	NP_001059117.1. NM_001065652.1.
UniGene	Os.5949.
3D structure databases
ProteinModelPortal	Q6ZDQ1.
ModBase	Search...
Proteomic databases
PRIDE	Q6ZDQ1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os07g09720.1; LOC_Os07g09720.1; LOC_Os07g09720.
GeneID	4342646.
KEGG	osa:4342646.
Organism-specific databases
Gramene	Q6ZDQ1.
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000210027.
KO	K01836.
OMA	DIVRVYA.
ProtClustDB	PLN02895.
Enzyme and pathway databases
UniPathway	UPA00113; UER00530.
Gene expression databases
ArrayExpress	Q6ZDQ1.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR016657. PAGM. [Graphical view]
PANTHER	PTHR22573:SF3. PTHR22573:SF3. 1 hit.
Pfam	PF02878. PGM_PMM_I. 2 hits. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PIRSF	PIRSF016408. PAGM. 1 hit.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 4 hits.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AGM1_ORYSJ

Accession

Primary (citable) accession number: Q6ZDQ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program