Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q6ZDE3 (ABAH2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Abscisic acid 8'-hydroxylase 2

Short name=ABA 8'-hydroxylase 2
EC=1.14.13.93
Alternative name(s):
Cytochrome P450 707A6
OsABA8ox2
Gene names
Name:CYP707A6
Synonyms:ABA8OX2
Ordered Locus Names:Os08g0472800, LOC_Os08g36860
ORF Names:OsJ_026541, P0013B04.19
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length510 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in the oxidative degradation of abscisic acid.

Catalytic activity

+-abscisate + NADPH + O2 = 8'-hydroxyabscisate + NADP+ + H2O.

Cofactor

Heme group By similarity.

Pathway

Plant hormone degradation; abscisic acid degradation.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Induction

Not induced by ethylene treatment or flooding. Ref.5

Sequence similarities

Belongs to the cytochrome P450 family.

Sequence caution

The sequence EAZ43058.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 510510Abscisic acid 8'-hydroxylase 2
PRO_0000288646

Regions

Transmembrane3 – 2321Helical; Potential
Compositional bias45 – 484Poly-Lys
Compositional bias260 – 28425Gly-rich

Sites

Metal binding4411Iron (heme axial ligand) By similarity

Experimental info

Sequence conflict4301T → S in AK120757. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q6ZDE3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: C1F583725741091E

FASTA51056,556
        10         20         30         40         50         60 
MAFLLFFVFV TAAVLCFVVP AFLLLCTSVQ RRRDVGQGGG RDWQKKKKLR LPPGSMGWPY 

        70         80         90        100        110        120 
VGETLQLYSQ DPNVFFASKQ KRYGEIFKTN LLGCPCVMLA SPEAARFVLV SQARLFKPTY 

       130        140        150        160        170        180 
PPSKERMIGP SALFFHQGEY HLRLRRLVQA ALAPDSLRAL VPDVDAAVAA TLAAWSGGHV 

       190        200        210        220        230        240 
ASTFHAMKKL SFDVGVVTIF GGRLGRRHRE ELRTNYSVVE RGYNCFPNRF PGTLYHKAIQ 

       250        260        270        280        290        300 
ARKRLRAILS EIVAERRARG GGGGGGGDDL LGGLMRSRDD GTAGAVALLT DDQIADNVVG 

       310        320        330        340        350        360 
VLFAAQDTTA SVLTWILKYL HDSPKLLEAV KAEQMAIYVA NEGGKRPLTW TQTRSMTLTH 

       370        380        390        400        410        420 
QVILESLRMA SIISFTFREA VADVEYKGFL IPKGWKVMPL FRNIHHNPDY FQDPQKFDPS 

       430        440        450        460        470        480 
RFKVAPRPST FLPFGSGVHA CPGNELAKLE MLVLVHRLVT AYRWEIVGAS DEVEYSPFPV 

       490        500        510 
PRGGLNAKLW KQEAEEDMYM AMGTITAAGA 

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[5]"Ethylene promotes submergence-induced expression of OsABA8ox1, a gene that encodes ABA 8'-hydroxylase in rice."
Saika H., Okamoto M., Miyoshi K., Kushiro T., Shinoda S., Jikumaru Y., Fujimoto M., Arikawa T., Takahashi H., Ando M., Arimura S., Miyao A., Hirochika H., Kamiya Y., Tsutsumi N., Nambara E., Nakazono M.
Plant Cell Physiol. 48:287-298(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION, LACK OF INDUCTION.
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP004457 Genomic DNA. Translation: BAD09367.1.
AP008214 Genomic DNA. Translation: BAF23935.1.
CM000145 Genomic DNA. Translation: EAZ43058.1. Sequence problems.
AK120757 mRNA. No translation available.
RefSeqNP_001062021.1. NM_001068556.1.
UniGeneOs.50329.

3D structure databases

ProteinModelPortalQ6ZDE3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os08g36860.1.

Proteomic databases

PaxDbQ6ZDE3.
PRIDEQ6ZDE3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS08T0472800-01; OS08T0472800-01; OS08G0472800.
GeneID4345810.
KEGGosa:4345810.

Organism-specific databases

GrameneQ6ZDE3.

Phylogenomic databases

eggNOGCOG2124.
HOGENOMHOG000237614.
KOK09843.
OMANPEYFSD.
ProtClustDBCLSN2697395.

Enzyme and pathway databases

UniPathwayUPA00093.

Family and domain databases

Gene3D1.10.630.10. 1 hit.
InterProIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamPF00067. p450. 1 hit.
[Graphical view]
PRINTSPR00463. EP450I.
PR00385. P450.
SUPFAMSSF48264. SSF48264. 1 hit.
PROSITEPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameABAH2_ORYSJ
AccessionPrimary (citable) accession number: Q6ZDE3
Secondary accession number(s): A3BU19
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways