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Q6ZDE3

- ABAH2_ORYSJ

UniProt

Q6ZDE3 - ABAH2_ORYSJ

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Protein
Abscisic acid 8'-hydroxylase 2
Gene
CYP707A6, ABA8OX2, Os08g0472800, LOC_Os08g36860, OsJ_026541, P0013B04.19
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in the oxidative degradation of abscisic acid.

Catalytic activityi

+-abscisate + NADPH + O2 = 8'-hydroxyabscisate + NADP+ + H2O.

Cofactori

Heme group By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi441 – 4411Iron (heme axial ligand) By similarity

GO - Molecular functioni

  1. (+)-abscisic acid 8'-hydroxylase activity Source: UniProtKB-EC
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro

GO - Biological processi

  1. abscisic acid catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Ligandi

Heme, Iron, Metal-binding, NADP

Enzyme and pathway databases

UniPathwayiUPA00093.

Names & Taxonomyi

Protein namesi
Recommended name:
Abscisic acid 8'-hydroxylase 2 (EC:1.14.13.93)
Short name:
ABA 8'-hydroxylase 2
Alternative name(s):
Cytochrome P450 707A6
OsABA8ox2
Gene namesi
Name:CYP707A6
Synonyms:ABA8OX2
Ordered Locus Names:Os08g0472800, LOC_Os08g36860
ORF Names:OsJ_026541, P0013B04.19
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 8

Organism-specific databases

GrameneiQ6ZDE3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 510510Abscisic acid 8'-hydroxylase 2
PRO_0000288646Add
BLAST

Proteomic databases

PaxDbiQ6ZDE3.
PRIDEiQ6ZDE3.

Expressioni

Inductioni

Not induced by ethylene treatment or flooding.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os08g36860.1.

Structurei

3D structure databases

ProteinModelPortaliQ6ZDE3.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi45 – 484Poly-Lys
Compositional biasi260 – 28425Gly-rich
Add
BLAST

Sequence similaritiesi

Belongs to the cytochrome P450 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2124.
HOGENOMiHOG000237614.
KOiK09843.
OMAiKHETIAK.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ZDE3-1 [UniParc]FASTAAdd to Basket

« Hide

MAFLLFFVFV TAAVLCFVVP AFLLLCTSVQ RRRDVGQGGG RDWQKKKKLR    50
LPPGSMGWPY VGETLQLYSQ DPNVFFASKQ KRYGEIFKTN LLGCPCVMLA 100
SPEAARFVLV SQARLFKPTY PPSKERMIGP SALFFHQGEY HLRLRRLVQA 150
ALAPDSLRAL VPDVDAAVAA TLAAWSGGHV ASTFHAMKKL SFDVGVVTIF 200
GGRLGRRHRE ELRTNYSVVE RGYNCFPNRF PGTLYHKAIQ ARKRLRAILS 250
EIVAERRARG GGGGGGGDDL LGGLMRSRDD GTAGAVALLT DDQIADNVVG 300
VLFAAQDTTA SVLTWILKYL HDSPKLLEAV KAEQMAIYVA NEGGKRPLTW 350
TQTRSMTLTH QVILESLRMA SIISFTFREA VADVEYKGFL IPKGWKVMPL 400
FRNIHHNPDY FQDPQKFDPS RFKVAPRPST FLPFGSGVHA CPGNELAKLE 450
MLVLVHRLVT AYRWEIVGAS DEVEYSPFPV PRGGLNAKLW KQEAEEDMYM 500
AMGTITAAGA 510
Length:510
Mass (Da):56,556
Last modified:July 5, 2004 - v1
Checksum:iC1F583725741091E
GO

Sequence cautioni

The sequence EAZ43058.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti430 – 4301T → S in AK120757. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004457 Genomic DNA. Translation: BAD09367.1.
AP008214 Genomic DNA. Translation: BAF23935.1.
CM000145 Genomic DNA. Translation: EAZ43058.1. Sequence problems.
AK120757 mRNA. No translation available.
RefSeqiNP_001062021.1. NM_001068556.1.
UniGeneiOs.50329.

Genome annotation databases

EnsemblPlantsiOS08T0472800-01; OS08T0472800-01; OS08G0472800.
GeneIDi4345810.
KEGGiosa:4345810.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004457 Genomic DNA. Translation: BAD09367.1 .
AP008214 Genomic DNA. Translation: BAF23935.1 .
CM000145 Genomic DNA. Translation: EAZ43058.1 . Sequence problems.
AK120757 mRNA. No translation available.
RefSeqi NP_001062021.1. NM_001068556.1.
UniGenei Os.50329.

3D structure databases

ProteinModelPortali Q6ZDE3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os08g36860.1.

Proteomic databases

PaxDbi Q6ZDE3.
PRIDEi Q6ZDE3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS08T0472800-01 ; OS08T0472800-01 ; OS08G0472800 .
GeneIDi 4345810.
KEGGi osa:4345810.

Organism-specific databases

Gramenei Q6ZDE3.

Phylogenomic databases

eggNOGi COG2124.
HOGENOMi HOG000237614.
KOi K09843.
OMAi KHETIAK.

Enzyme and pathway databases

UniPathwayi UPA00093 .

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view ]
Pfami PF00067. p450. 1 hit.
[Graphical view ]
PRINTSi PR00463. EP450I.
PR00385. P450.
SUPFAMi SSF48264. SSF48264. 1 hit.
PROSITEi PS00086. CYTOCHROME_P450. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  5. Cited for: IDENTIFICATION, LACK OF INDUCTION.
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiABAH2_ORYSJ
AccessioniPrimary (citable) accession number: Q6ZDE3
Secondary accession number(s): A3BU19
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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