Reviewed,
UniProtKB/Swiss-Prot Q6ZDE3 (ABAH2_ORYSJ)
Last modified
November 25, 2008.
Version 39.
History...
Clusters with 100%,
90%,
50% identity |
Documents (4) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Abscisic acid 8'-hydroxylase 2 Short name=ABA 8'-hydroxylase 2 EC=1.14.13.93 Alternative name(s): OsABA8ox2 Cytochrome P450 707A6 | ||||||||
| Gene names |
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| Organism | Oryza sativa subsp. japonica (Rice) | ||||||||
| Taxonomic identifier | 39947 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza |
Protein attributes
| Sequence length | 510 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Involved in the oxidative degradation of abscisic acid. |
| Catalytic activity | (+)-abscisate + NADPH + O(2) = 8'-hydroxyabscisate + NADP(+) + H(2)O. |
| Cofactor | Heme group By similarity. |
| Pathway | |
| Subcellular location | Membrane; Single-pass membrane proteinPotential. |
| Induction | Not induced by ethylene treatment or flooding. |
| Sequence similarities | Belongs to the cytochrome P450 family. |
| Sequence caution | The sequence EAZ43058.1 differs from that shown. Reason: Erroneous gene model prediction. |
Ontologies
Keywords | |
|---|---|
| Cellular component | Membrane |
| Domain | Transmembrane |
| Ligand | Heme Iron Metal-binding NADP |
| Molecular function | Monooxygenase Oxidoreductase |
Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | (+)-abscisic acid 8'-hydroxylase activity Inferred from electronic annotation. Source: EC electron carrier activityInferred from electronic annotation. Source: InterPro heme bindingInferred from electronic annotation. Source: InterPro iron ion bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 510 | 510 | Abscisic acid 8'-hydroxylase 2 | PRO_0000288646 | |||||
Regions | |||||||||
| Transmembrane | 3 – 23 | 21 | Potential | ||||||
| Compositional bias | 45 – 48 | 4 | Poly-Lys | ||||||
| Compositional bias | 260 – 284 | 25 | Gly-rich | ||||||
Sites | |||||||||
| Metal binding | 441 | 1 | Iron (heme axial ligand) By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 430 | 1 | T → S in AK120757. Ref.4 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare. |
| [2] | "Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare. |
| [3] | "The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. Yang H.PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare. |
| [4] | "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare. |
| [5] | "Ethylene promotes submergence-induced expression of OsABA8ox1, a gene that encodes ABA 8'-hydroxylase in rice." Saika H., Okamoto M., Miyoshi K., Kushiro T., Shinoda S., Jikumaru Y., Fujimoto M., Arikawa T., Takahashi H., Ando M., Arimura S., Miyao A., Hirochika H., Kamiya Y., Tsutsumi N., Nambara E., Nakazono M. Plant Cell Physiol. 48:287-298(2007) [PubMed: 17205969] [Abstract] Cited for: IDENTIFICATION, LACK OF INDUCTION. Strain: cv. Nipponbare. |
Cross-references
Sequence databases | |
|---|---|
| AP004457 Genomic DNA. Translation: BAD09367.1. AP008214 Genomic DNA. Translation: BAF23935.1. CM000145 Genomic DNA. Translation: EAZ43058.1. Sequence problems. AK120757 mRNA. No translation available. | |
| RefSeq | NP_001062021.1. |
| UniGene | Os.50329 |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4345810. |
| KEGG | osa:4345810. |
Organism-specific databases | |
| Gramene | Q6ZDE3. |
Family and domain databases | |
| InterPro | IPR001128. Cyt_P450. IPR002401. Cyt_P450_E_grp-I. [Graphical view] |
| Gene3D | G3DSA:1.10.630.10. Cyt_P450. 1 hit. |
| PANTHER | PTHR19383. Cyt_P450. 1 hit. |
| Pfam | PF00067. p450. 1 hit. [Graphical view] |
| PRINTS | PR00463. EP450I. PR00385. P450. |
| PROSITE | PS00086. CYTOCHROME_P450. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ABAH2_ORYSJ | ||||||||
| Accession | Primary (citable) accession number: Q6ZDE3 Secondary accession number(s): A3BU19 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Oryza sativa (rice) Index of Oryza sativa entries and their corresponding gene designations |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| UniProtKB secondary accession numbers Index of UniProtKB secondary accession numbers |
| SIMILARITY comments Index of protein domains and families |

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