Reviewed, UniProtKB/Swiss-Prot Q6ZAG3 (CDKC3_ORYSJ)

Names and origin

Protein names

Recommended name:
    Cyclin-dependent kinase C-3
      Short name=CDKC;3
    EC=2.7.11.22
    EC=2.7.11.23

Gene names

Name:	CDKC-1
Ordered Locus Names:	Os08g0453800, LOC_Os08g35220
ORF Names:	P0048G02.5, OsJ_026440

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	324 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Sequence similarities	Belongs to the Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.
Sequence caution	The sequence BAD09782.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAF23871.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA polymerase II carboxy-terminal domain kinase activity Inferred from electronic annotation. Source: EC cyclin-dependent protein kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 324	324	Cyclin-dependent kinase C-3		PRO_0000296102
Regions
	Domain	27 – 320	294	Protein kinase
	Nucleotide binding	33 – 41	9	ATP By similarity
Sites
	Active site	160	1	Proton acceptor By similarity
	Binding site	56	1	ATP By similarity
Amino acid modifications
	Modified residue	37	1	Phosphothreonine By similarity
	Modified residue	38	1	Phosphotyrosine By similarity
	Modified residue	193	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6ZAG3-1 [UniParc]. Last modified July 24, 2007. Version 2. Checksum: 5E56F7CC256597F9	FASTA	324	36,762
	10 20 30 40 50 60 MDGEEAPPGA LNLADYAPAG ARTVDCFRRI RKIGEGTYGE VFEAMDIITG ERAALKKIKL 70 80 90 100 110 120 DDGKEGFPRQ ILREIKLLKK LDHENIIRLK EIVVSPGTAH GAGGSDDYMY RGDIYMVFEY 130 140 150 160 170 180 MDHDLKKVLH HSTPSQVKYY MEQLLKGLHY CHVNNVLHRD IKGANLLISG GGKLLKLADF 190 200 210 220 230 240 GLARPFTRDG SFTNHVITLW YRPPELLLGA TNYAEAVDIW SVGCIFAEFL LRKPLFPGRT 250 260 270 280 290 300 EQEQLSKIFE LCGFPNEENW PGVSKLPLYK TIRPTTPTKR RLRDIFHNFD SHAVDLIDRM 310 320 LILNPTERIS AHDALCAAYF ITKM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Genome-wide identification and expression analysis of rice cell cycle genes." Guo J., Song J., Wang F., Zhang X.S. Plant Mol. Biol. 64:349-360(2007) [PubMed: 17443292] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP004662 Genomic DNA. Translation: BAD09782.1. Sequence problems. AP008214 Genomic DNA. Translation: BAF23871.1. Sequence problems. CM000145 Genomic DNA. No translation available.
RefSeq	NP_001061957.1.
UniGene	Os.80607
3D structure databases
HSSP	HSSP built from PDB template 1B38 based on UniProtKB P24941.
ModBase	Search...
Genome annotation databases
GeneID	4345743.
KEGG	osa:4345743.
Organism-specific databases
Gramene	Q6ZAG3.
Family and domain databases
InterPro	IPR000719. Prot_kinase_core. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_pkinase-rel. IPR008271. Ser_thr_pkin_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CDKC3_ORYSJ

Accession

Primary (citable) accession number: Q6ZAG3
Secondary accession number(s): Q0J594

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	November 3, 2009
This is version 51 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)