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Q6Z8C8

- CDKF4_ORYSJ

UniProt

Q6Z8C8 - CDKF4_ORYSJ

Protein

Cyclin-dependent kinase F-4

Gene

CDKF-4

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.
    ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei33 – 331ATPPROSITE-ProRule annotation
    Active sitei125 – 1251Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 189ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
    3. RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cyclin-dependent kinase F-4 (EC:2.7.11.22, EC:2.7.11.23)
    Short name:
    CDKF;4
    Alternative name(s):
    Serine/threonine-protein kinase MHK-like protein 2
    Gene namesi
    Name:CDKF-4
    Ordered Locus Names:Os02g0700600, LOC_Os02g47220
    ORF Names:OJ1111_E07.13-1, P0459B01.42-1
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 2

    Organism-specific databases

    GrameneiQ6Z8C8.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 459459Cyclin-dependent kinase F-4PRO_0000296109Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei151 – 1511PhosphoserineBy similarity
    Modified residuei156 – 1561PhosphothreonineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PRIDEiQ6Z8C8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6Z8C8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 283280Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000233024.
    OMAiSEADEIH.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6Z8C8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDRFKMIKEV GDGTFGSVWR AINKQNGEVV AVKKMKRKYY SFEECMSLRE    50
    VKSLRRMNHP NIVKLKEVIR ENDILYFIME YMECNLYQLM KDRVKPFSEA 100
    EVRNWCFQIF QALAYMHQRG YFHRDLKPEN LLVSKDVIKL ADFGLAREVT 150
    SVPPYTEYVS TRWYRAPEVL LQSSIYDSAV DMWAMGAIMA ELLTLHPLFP 200
    GTSEADEILK ICNVIGSPDE QSWPQGLSLA ETMKFQFPQV SGNQLAEVMT 250
    SVSSEAVDLI SSLCSWDPCK RPKAAEVLQH TFFQGCTFVP PTVRSKAGVL 300
    PKTPPCVGVK GVSEHGMPRR YSTGTLSTTK PHSNASLKSS GLSKTGVQRK 350
    LQMDRQAPQK IKKPTESNNK LTTNRVPARN SPGHPVLRHS RSLPETGRAT 400
    MHKVSTLTER LTHMSVTSRT RTTPKPAAPL LKAGLGKSDL LGKTDEIPPA 450
    KRLTRKLVS 459
    Length:459
    Mass (Da):51,720
    Last modified:July 5, 2004 - v1
    Checksum:iB527ED78C8B15E1F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003994 Genomic DNA. Translation: BAD07520.1.
    AP004778 Genomic DNA. Translation: BAD07891.1.
    AP008208 Genomic DNA. Translation: BAF09755.1.
    AK100056 mRNA. No translation available.
    RefSeqiNP_001047841.1. NM_001054376.1.
    UniGeneiOs.12650.

    Genome annotation databases

    EnsemblPlantsiOS02T0700600-01; OS02T0700600-01; OS02G0700600.
    GeneIDi4330434.
    KEGGiosa:4330434.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP003994 Genomic DNA. Translation: BAD07520.1 .
    AP004778 Genomic DNA. Translation: BAD07891.1 .
    AP008208 Genomic DNA. Translation: BAF09755.1 .
    AK100056 mRNA. No translation available.
    RefSeqi NP_001047841.1. NM_001054376.1.
    UniGenei Os.12650.

    3D structure databases

    ProteinModelPortali Q6Z8C8.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q6Z8C8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS02T0700600-01 ; OS02T0700600-01 ; OS02G0700600 .
    GeneIDi 4330434.
    KEGGi osa:4330434.

    Organism-specific databases

    Gramenei Q6Z8C8.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000233024.
    OMAi SEADEIH.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    3. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.
    4. "Genome-wide identification and expression analysis of rice cell cycle genes."
      Guo J., Song J., Wang F., Zhang X.S.
      Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY.

    Entry informationi

    Entry nameiCDKF4_ORYSJ
    AccessioniPrimary (citable) accession number: Q6Z8C8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 24, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3