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Protein

Cyclin-dependent kinase F-4

Gene

CDKF-4

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33ATPPROSITE-ProRule annotation1
Active sitei125Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 18ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase F-4 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKF;4
Alternative name(s):
Serine/threonine-protein kinase MHK-like protein 2
Gene namesi
Name:CDKF-4
Ordered Locus Names:Os02g0700600, LOC_Os02g47220
ORF Names:OJ1111_E07.13-1, OsJ_08052Imported, P0459B01.42-1
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002961091 – 459Cyclin-dependent kinase F-4Add BLAST459

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei151PhosphoserineBy similarity1
Modified residuei156PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6Z8C8.
PRIDEiQ6Z8C8.

Expressioni

Gene expression databases

ExpressionAtlasiQ6Z8C8. baseline and differential.
GenevisibleiQ6Z8C8. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g47220.1.

Structurei

3D structure databases

ProteinModelPortaliQ6Z8C8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 283Protein kinasePROSITE-ProRule annotationAdd BLAST280

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0661. Eukaryota.
ENOG410XPBB. LUCA.
HOGENOMiHOG000233024.
InParanoidiQ6Z8C8.
OMAiSEADEIH.
OrthoDBiEOG093608EM.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6Z8C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRFKMIKEV GDGTFGSVWR AINKQNGEVV AVKKMKRKYY SFEECMSLRE
60 70 80 90 100
VKSLRRMNHP NIVKLKEVIR ENDILYFIME YMECNLYQLM KDRVKPFSEA
110 120 130 140 150
EVRNWCFQIF QALAYMHQRG YFHRDLKPEN LLVSKDVIKL ADFGLAREVT
160 170 180 190 200
SVPPYTEYVS TRWYRAPEVL LQSSIYDSAV DMWAMGAIMA ELLTLHPLFP
210 220 230 240 250
GTSEADEILK ICNVIGSPDE QSWPQGLSLA ETMKFQFPQV SGNQLAEVMT
260 270 280 290 300
SVSSEAVDLI SSLCSWDPCK RPKAAEVLQH TFFQGCTFVP PTVRSKAGVL
310 320 330 340 350
PKTPPCVGVK GVSEHGMPRR YSTGTLSTTK PHSNASLKSS GLSKTGVQRK
360 370 380 390 400
LQMDRQAPQK IKKPTESNNK LTTNRVPARN SPGHPVLRHS RSLPETGRAT
410 420 430 440 450
MHKVSTLTER LTHMSVTSRT RTTPKPAAPL LKAGLGKSDL LGKTDEIPPA

KRLTRKLVS
Length:459
Mass (Da):51,720
Last modified:July 5, 2004 - v1
Checksum:iB527ED78C8B15E1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003994 Genomic DNA. Translation: BAD07520.1.
AP004778 Genomic DNA. Translation: BAD07891.1.
AP008208 Genomic DNA. Translation: BAF09755.1.
AP014958 Genomic DNA. Translation: BAS80463.1.
CM000139 Genomic DNA. Translation: EEE57632.1.
AK100056 mRNA. Translation: BAG94420.1.
RefSeqiXP_015626442.1. XM_015770956.1.
XP_015626443.1. XM_015770957.1.
XP_015626444.1. XM_015770958.1.
UniGeneiOs.12650.

Genome annotation databases

EnsemblPlantsiOS02T0700600-01; OS02T0700600-01; OS02G0700600.
GeneIDi4330434.
GrameneiOS02T0700600-01; OS02T0700600-01; OS02G0700600.
KEGGiosa:4330434.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003994 Genomic DNA. Translation: BAD07520.1.
AP004778 Genomic DNA. Translation: BAD07891.1.
AP008208 Genomic DNA. Translation: BAF09755.1.
AP014958 Genomic DNA. Translation: BAS80463.1.
CM000139 Genomic DNA. Translation: EEE57632.1.
AK100056 mRNA. Translation: BAG94420.1.
RefSeqiXP_015626442.1. XM_015770956.1.
XP_015626443.1. XM_015770957.1.
XP_015626444.1. XM_015770958.1.
UniGeneiOs.12650.

3D structure databases

ProteinModelPortaliQ6Z8C8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os02g47220.1.

Proteomic databases

PaxDbiQ6Z8C8.
PRIDEiQ6Z8C8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS02T0700600-01; OS02T0700600-01; OS02G0700600.
GeneIDi4330434.
GrameneiOS02T0700600-01; OS02T0700600-01; OS02G0700600.
KEGGiosa:4330434.

Phylogenomic databases

eggNOGiKOG0661. Eukaryota.
ENOG410XPBB. LUCA.
HOGENOMiHOG000233024.
InParanoidiQ6Z8C8.
OMAiSEADEIH.
OrthoDBiEOG093608EM.

Gene expression databases

ExpressionAtlasiQ6Z8C8. baseline and differential.
GenevisibleiQ6Z8C8. OS.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCDKF4_ORYSJ
AccessioniPrimary (citable) accession number: Q6Z8C8
Secondary accession number(s): B7EPX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 5, 2004
Last modified: October 5, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.