UniProtKB - Q6Z8C8 (CDKF4_ORYSJ)
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Protein
Cyclin-dependent kinase F-4
Gene
CDKF-4
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Catalytic activityi
ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 33 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 125 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 10 – 18 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
- protein serine/threonine kinase activity Source: GO_Central
- RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC
GO - Biological processi
- intracellular signal transduction Source: GO_Central
- regulation of gene expression Source: GO_Central
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:CDKF-4 Ordered Locus Names:Os02g0700600, LOC_Os02g47220 ORF Names:OJ1111_E07.13-1, OsJ_08052Imported, P0459B01.42-1 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000296109 | 1 – 459 | Cyclin-dependent kinase F-4Add BLAST | 459 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 151 | PhosphoserineBy similarity | 1 | |
Modified residuei | 156 | PhosphothreonineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | Q6Z8C8. |
PRIDEi | Q6Z8C8. |
Expressioni
Gene expression databases
ExpressionAtlasi | Q6Z8C8. baseline and differential. |
Genevisiblei | Q6Z8C8. OS. |
Structurei
3D structure databases
ProteinModelPortali | Q6Z8C8. |
SMRi | Q6Z8C8. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 283 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 280 |
Sequence similaritiesi
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.Curated
Phylogenomic databases
eggNOGi | KOG0661. Eukaryota. ENOG410XPBB. LUCA. |
HOGENOMi | HOG000233024. |
InParanoidi | Q6Z8C8. |
OMAi | ENIMCNG. |
OrthoDBi | EOG093608EM. |
Family and domain databases
InterProi | View protein in InterPro IPR011009. Kinase-like_dom_sf. IPR000719. Prot_kinase_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS. |
Pfami | View protein in Pfam PF00069. Pkinase. 1 hit. |
SMARTi | View protein in SMART SM00220. S_TKc. 1 hit. |
SUPFAMi | SSF56112. SSF56112. 1 hit. |
PROSITEi | View protein in PROSITE PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q6Z8C8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDRFKMIKEV GDGTFGSVWR AINKQNGEVV AVKKMKRKYY SFEECMSLRE
60 70 80 90 100
VKSLRRMNHP NIVKLKEVIR ENDILYFIME YMECNLYQLM KDRVKPFSEA
110 120 130 140 150
EVRNWCFQIF QALAYMHQRG YFHRDLKPEN LLVSKDVIKL ADFGLAREVT
160 170 180 190 200
SVPPYTEYVS TRWYRAPEVL LQSSIYDSAV DMWAMGAIMA ELLTLHPLFP
210 220 230 240 250
GTSEADEILK ICNVIGSPDE QSWPQGLSLA ETMKFQFPQV SGNQLAEVMT
260 270 280 290 300
SVSSEAVDLI SSLCSWDPCK RPKAAEVLQH TFFQGCTFVP PTVRSKAGVL
310 320 330 340 350
PKTPPCVGVK GVSEHGMPRR YSTGTLSTTK PHSNASLKSS GLSKTGVQRK
360 370 380 390 400
LQMDRQAPQK IKKPTESNNK LTTNRVPARN SPGHPVLRHS RSLPETGRAT
410 420 430 440 450
MHKVSTLTER LTHMSVTSRT RTTPKPAAPL LKAGLGKSDL LGKTDEIPPA
KRLTRKLVS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP003994 Genomic DNA. Translation: BAD07520.1. AP004778 Genomic DNA. Translation: BAD07891.1. AP008208 Genomic DNA. Translation: BAF09755.1. AP014958 Genomic DNA. Translation: BAS80463.1. CM000139 Genomic DNA. Translation: EEE57632.1. AK100056 mRNA. Translation: BAG94420.1. |
RefSeqi | XP_015626442.1. XM_015770956.1. XP_015626443.1. XM_015770957.1. XP_015626444.1. XM_015770958.1. |
UniGenei | Os.12650. |
Genome annotation databases
EnsemblPlantsi | Os02t0700600-01; Os02t0700600-01; Os02g0700600. |
GeneIDi | 4330434. |
Gramenei | Os02t0700600-01; Os02t0700600-01; Os02g0700600. |
KEGGi | osa:4330434. |
Similar proteinsi
Entry informationi
Entry namei | CDKF4_ORYSJ | |
Accessioni | Q6Z8C8Primary (citable) accession number: Q6Z8C8 Secondary accession number(s): B7EPX3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 24, 2007 |
Last sequence update: | July 5, 2004 | |
Last modified: | February 28, 2018 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |