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Q6Z8C8

- CDKF4_ORYSJ

UniProt

Q6Z8C8 - CDKF4_ORYSJ

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Protein

Cyclin-dependent kinase F-4

Gene
CDKF-4, Os02g0700600, LOC_Os02g47220, OJ1111_E07.13-1, P0459B01.42-1
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331ATP By similarity
Active sitei125 – 1251Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
  3. RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase F-4 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKF;4
Alternative name(s):
Serine/threonine-protein kinase MHK-like protein 2
Gene namesi
Name:CDKF-4
Ordered Locus Names:Os02g0700600, LOC_Os02g47220
ORF Names:OJ1111_E07.13-1, P0459B01.42-1
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 2

Organism-specific databases

GrameneiQ6Z8C8.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459Cyclin-dependent kinase F-4PRO_0000296109Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei151 – 1511Phosphoserine By similarity
Modified residuei156 – 1561Phosphothreonine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ6Z8C8.

Structurei

3D structure databases

ProteinModelPortaliQ6Z8C8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 283280Protein kinaseAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
OMAiSEADEIH.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6Z8C8-1 [UniParc]FASTAAdd to Basket

« Hide

MDRFKMIKEV GDGTFGSVWR AINKQNGEVV AVKKMKRKYY SFEECMSLRE    50
VKSLRRMNHP NIVKLKEVIR ENDILYFIME YMECNLYQLM KDRVKPFSEA 100
EVRNWCFQIF QALAYMHQRG YFHRDLKPEN LLVSKDVIKL ADFGLAREVT 150
SVPPYTEYVS TRWYRAPEVL LQSSIYDSAV DMWAMGAIMA ELLTLHPLFP 200
GTSEADEILK ICNVIGSPDE QSWPQGLSLA ETMKFQFPQV SGNQLAEVMT 250
SVSSEAVDLI SSLCSWDPCK RPKAAEVLQH TFFQGCTFVP PTVRSKAGVL 300
PKTPPCVGVK GVSEHGMPRR YSTGTLSTTK PHSNASLKSS GLSKTGVQRK 350
LQMDRQAPQK IKKPTESNNK LTTNRVPARN SPGHPVLRHS RSLPETGRAT 400
MHKVSTLTER LTHMSVTSRT RTTPKPAAPL LKAGLGKSDL LGKTDEIPPA 450
KRLTRKLVS 459
Length:459
Mass (Da):51,720
Last modified:July 5, 2004 - v1
Checksum:iB527ED78C8B15E1F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP003994 Genomic DNA. Translation: BAD07520.1.
AP004778 Genomic DNA. Translation: BAD07891.1.
AP008208 Genomic DNA. Translation: BAF09755.1.
AK100056 mRNA. No translation available.
RefSeqiNP_001047841.1. NM_001054376.1.
UniGeneiOs.12650.

Genome annotation databases

EnsemblPlantsiOS02T0700600-01; OS02T0700600-01; OS02G0700600.
GeneIDi4330434.
KEGGiosa:4330434.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP003994 Genomic DNA. Translation: BAD07520.1 .
AP004778 Genomic DNA. Translation: BAD07891.1 .
AP008208 Genomic DNA. Translation: BAF09755.1 .
AK100056 mRNA. No translation available.
RefSeqi NP_001047841.1. NM_001054376.1.
UniGenei Os.12650.

3D structure databases

ProteinModelPortali Q6Z8C8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6Z8C8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS02T0700600-01 ; OS02T0700600-01 ; OS02G0700600 .
GeneIDi 4330434.
KEGGi osa:4330434.

Organism-specific databases

Gramenei Q6Z8C8.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
OMAi SEADEIH.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  4. "Genome-wide identification and expression analysis of rice cell cycle genes."
    Guo J., Song J., Wang F., Zhang X.S.
    Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiCDKF4_ORYSJ
AccessioniPrimary (citable) accession number: Q6Z8C8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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