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Q6Z829

- WEE1_ORYSJ

UniProt

Q6Z829 - WEE1_ORYSJ

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Protein

Wee1-like protein kinase

Gene
WEE1, Os02g0135300, LOC_Os02g04240, P0585B01.27
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei296 – 2961ATP By similarity
Active sitei387 – 3871Proton acceptor By similarity
Metal bindingi392 – 3921Magnesium; via carbonyl oxygen By similarity
Metal bindingi404 – 4041Magnesium; via carbonyl oxygen By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi273 – 2819ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. non-membrane spanning protein tyrosine kinase activity Source: UniProtKB-EC
  4. protein serine/threonine kinase activity Source: InterPro

GO - Biological processi

  1. cell cycle arrest Source: EnsemblPlants/Gramene
  2. DNA replication checkpoint Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase, Tyrosine-protein kinase

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Wee1-like protein kinase (EC:2.7.10.2)
Gene namesi
Name:WEE1
Ordered Locus Names:Os02g0135300, LOC_Os02g04240
ORF Names:P0585B01.27
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 2

Organism-specific databases

GrameneiQ6Z829.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 520520Wee1-like protein kinasePRO_0000295673Add
BLAST

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliQ6Z829.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini267 – 510244Protein kinaseAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000083236.
OMAiRYRTDFH.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6Z829-1 [UniParc]FASTAAdd to Basket

« Hide

MLRTKTPRPR GGKSRRATAA AGKERERERE REREGRSPSG ELSLQLEHVS    50
LFSFLADAPR EGAAAARTPF TPFEELLEGS CDPDPTPPPP LPPLQPQATP 100
MDADEVVEEK DSGILSQDFF CTPDYITPDA PQLGSGFDAN KENIPCPNSP 150
EKSVCRSKRY KRDCSPKGLG SNDIFDSQWI APVQFEGLDD SEEEQLKESS 200
SHKRGSYVSQ SAVALRCRVM PPPCIRNPYL NTDHQIDDNV FGGRQCKSSG 250
FSPSVDGDGL SRYRTDFHEI EQIGRGNFSV VFKVLKRIDG CLYAVKRSIR 300
QLHNDRERRQ AVKEVQALAA LGCHENIVGY FTSWFENKQL FIQMELCDRC 350
LSMDRNQPLK CGEALELLYQ ICKGLDFIHE RGIAHLDVKP DNIYVRNGVY 400
KLGDFGCATL IDRSLAIEDG DSRYMPPEML NDKYEHLDKV DIFSLGAAIY 450
ELIRGTQLPD SGPQFTSLRE GKIALLPGCP MQFQSLIKSM MDPDPVRRPS 500
AKEVLRHPIF DKLHKAPAKK 520
Length:520
Mass (Da):58,391
Last modified:July 5, 2004 - v1
Checksum:i934F492877B99F9F
GO

Sequence cautioni

The sequence BAF07730.2 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004799 Genomic DNA. Translation: BAD10095.1.
AP008208 Genomic DNA. Translation: BAF07730.2. Sequence problems.
RefSeqiNP_001045816.2. NM_001052351.2.
UniGeneiOs.98767.

Genome annotation databases

EnsemblPlantsiOS02T0135300-00; OS02T0135300-00; OS02G0135300.
GeneIDi4328224.
KEGGiosa:4328224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP004799 Genomic DNA. Translation: BAD10095.1 .
AP008208 Genomic DNA. Translation: BAF07730.2 . Sequence problems.
RefSeqi NP_001045816.2. NM_001052351.2.
UniGenei Os.98767.

3D structure databases

ProteinModelPortali Q6Z829.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS02T0135300-00 ; OS02T0135300-00 ; OS02G0135300 .
GeneIDi 4328224.
KEGGi osa:4328224.

Organism-specific databases

Gramenei Q6Z829.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000083236.
OMAi RYRTDFH.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "Genome-wide identification and expression analysis of rice cell cycle genes."
    Guo J., Song J., Wang F., Zhang X.S.
    Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiWEE1_ORYSJ
AccessioniPrimary (citable) accession number: Q6Z829
Secondary accession number(s): Q0E458
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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