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Q6Z4P2

- APY2_ORYSJ

UniProt

Q6Z4P2 - APY2_ORYSJ

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Protein

Probable apyrase 2

Gene
APY2, Os07g0682800, LOC_Os07g48430, OsJ_25612, OSJNBa0060O17.4
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates By similarity.

Catalytic activityi

A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

Cofactori

Calcium By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei192 – 1921Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi70 – 8011ATP-binding InferredAdd
BLAST
Nucleotide bindingi216 – 22611ATP-binding InferredAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. guanosine-diphosphatase activity Source: EnsemblPlants/Gramene
  3. inosine-diphosphatase activity Source: EnsemblPlants/Gramene
  4. uridine-diphosphatase activity Source: EnsemblPlants/Gramene

GO - Biological processi

  1. pollen germination Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Calcium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable apyrase 2 (EC:3.6.1.5)
Short name:
OsAPY2
Alternative name(s):
ATP-diphosphatase
ATP-diphosphohydrolase
Adenosine diphosphatase
Short name:
ADPase
Gene namesi
Name:APY2
Ordered Locus Names:Os07g0682800, LOC_Os07g48430
ORF Names:OsJ_25612, OSJNBa0060O17.4
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 7

Organism-specific databases

GrameneiQ6Z4P2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2525Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei26 – 4621Helical; Signal-anchor for type II membrane protein; Reviewed predictionAdd
BLAST
Topological domaini47 – 467421Extracellular Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. endosome Source: EnsemblPlants/Gramene
  2. integral component of membrane Source: UniProtKB-KW
  3. trans-Golgi network Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Probable apyrase 2PRO_0000419908Add
BLAST

Proteomic databases

PRIDEiQ6Z4P2.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi348 – 3536Poly-Gly

Sequence similaritiesi

Belongs to the GDA1/CD39 NTPase family.

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5371.
KOiK14641.
OMAiDNIPYIC.

Family and domain databases

InterProiIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERiPTHR11782. PTHR11782. 1 hit.
PfamiPF01150. GDA1_CD39. 1 hit.
[Graphical view]
PROSITEiPS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6Z4P2-1 [UniParc]FASTAAdd to Basket

« Hide

MRRYSALPGG GARPDTLADR LHRYRGVLLV ILAPLALVSL VLLLMPRSPA    50
SSSAAAGRRW GPLDANKYAV IFDAGSSGSR VHVFRFDANL DLLHIGDQIE 100
LFVQKKPGLS EYANNPQEAA KSLVSLLEDA KRVVPVELRG QTPVRVGATA 150
GLRALGAEKS EEILQAVRDL LREKSSFKTQ PDWVTVLDGP QEGAYEWVTI 200
NYLLGKLGKT YADTVGVVDL GGGSVQMAYA IAEKDAVKAP KPSEGEDSYV 250
KKLFLKGTTY YLYVHSYLHY GLLAARAEIL KAGNGKGYSY CTLEGHQGQY 300
KYGNGKFEAS ASPSGASYSK CRDDVVKALK VDQACTHMKC SFGGIWNGGG 350
GAGQKNLFVA SFFFDRAAEA GFVNPKAPVA KVKPSDFEKA AKRACKLNLK 400
DAEAAYPGVQ KDNIPYICMD LVYQYTLLVD GFGVGSHQEM TLVKKVPYSN 450
AFVEAAWPLG SAIEVAS 467
Length:467
Mass (Da):50,438
Last modified:July 5, 2004 - v1
Checksum:i22B61F6F36D43C3E
GO

Sequence cautioni

The sequence AK066262 differs from that shown. Reason: Erroneous termination at position 464. Translated as Glu.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP005167 Genomic DNA. Translation: BAC83798.1.
AP008213 Genomic DNA. Translation: BAF22577.1.
CM000144 Genomic DNA. Translation: EAZ41118.1.
AK066262 mRNA. No translation available.
RefSeqiNP_001060663.1. NM_001067198.1.
UniGeneiOs.26730.

Genome annotation databases

GeneIDi4344315.
KEGGiosa:4344315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP005167 Genomic DNA. Translation: BAC83798.1 .
AP008213 Genomic DNA. Translation: BAF22577.1 .
CM000144 Genomic DNA. Translation: EAZ41118.1 .
AK066262 mRNA. No translation available.
RefSeqi NP_001060663.1. NM_001067198.1.
UniGenei Os.26730.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6Z4P2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4344315.
KEGGi osa:4344315.

Organism-specific databases

Gramenei Q6Z4P2.

Phylogenomic databases

eggNOGi COG5371.
KOi K14641.
OMAi DNIPYIC.

Family and domain databases

InterProi IPR000407. GDA1_CD39_NTPase.
[Graphical view ]
PANTHERi PTHR11782. PTHR11782. 1 hit.
Pfami PF01150. GDA1_CD39. 1 hit.
[Graphical view ]
PROSITEi PS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiAPY2_ORYSJ
AccessioniPrimary (citable) accession number: Q6Z4P2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2012
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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