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Q6Z4P2

- APY2_ORYSJ

UniProt

Q6Z4P2 - APY2_ORYSJ

Protein

Probable apyrase 2

Gene

APY2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates.By similarity

    Catalytic activityi

    A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

    Cofactori

    Calcium.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei192 – 1921Proton acceptorBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi70 – 8011ATP-bindingCuratedAdd
    BLAST
    Nucleotide bindingi216 – 22611ATP-bindingCuratedAdd
    BLAST

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. guanosine-diphosphatase activity Source: EnsemblPlants/Gramene
    3. inosine-diphosphatase activity Source: EnsemblPlants/Gramene
    4. uridine-diphosphatase activity Source: EnsemblPlants/Gramene

    GO - Biological processi

    1. pollen germination Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    ATP-binding, Calcium, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable apyrase 2 (EC:3.6.1.5)
    Short name:
    OsAPY2
    Alternative name(s):
    ATP-diphosphatase
    ATP-diphosphohydrolase
    Adenosine diphosphatase
    Short name:
    ADPase
    Gene namesi
    Name:APY2
    Ordered Locus Names:Os07g0682800, LOC_Os07g48430
    ORF Names:OsJ_25612, OSJNBa0060O17.4
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 7

    Organism-specific databases

    GrameneiQ6Z4P2.

    Subcellular locationi

    Membrane By similarity; Single-pass type II membrane protein By similarity

    GO - Cellular componenti

    1. endosome Source: EnsemblPlants/Gramene
    2. integral component of membrane Source: UniProtKB-KW
    3. trans-Golgi network Source: EnsemblPlants/Gramene

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 467467Probable apyrase 2PRO_0000419908Add
    BLAST

    Proteomic databases

    PRIDEiQ6Z4P2.

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2525CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini47 – 467421ExtracellularSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei26 – 4621Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi348 – 3536Poly-Gly

    Sequence similaritiesi

    Belongs to the GDA1/CD39 NTPase family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG5371.
    KOiK14641.
    OMAiDNIPYIC.

    Family and domain databases

    InterProiIPR000407. GDA1_CD39_NTPase.
    [Graphical view]
    PANTHERiPTHR11782. PTHR11782. 1 hit.
    PfamiPF01150. GDA1_CD39. 1 hit.
    [Graphical view]
    PROSITEiPS01238. GDA1_CD39_NTPASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6Z4P2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRRYSALPGG GARPDTLADR LHRYRGVLLV ILAPLALVSL VLLLMPRSPA    50
    SSSAAAGRRW GPLDANKYAV IFDAGSSGSR VHVFRFDANL DLLHIGDQIE 100
    LFVQKKPGLS EYANNPQEAA KSLVSLLEDA KRVVPVELRG QTPVRVGATA 150
    GLRALGAEKS EEILQAVRDL LREKSSFKTQ PDWVTVLDGP QEGAYEWVTI 200
    NYLLGKLGKT YADTVGVVDL GGGSVQMAYA IAEKDAVKAP KPSEGEDSYV 250
    KKLFLKGTTY YLYVHSYLHY GLLAARAEIL KAGNGKGYSY CTLEGHQGQY 300
    KYGNGKFEAS ASPSGASYSK CRDDVVKALK VDQACTHMKC SFGGIWNGGG 350
    GAGQKNLFVA SFFFDRAAEA GFVNPKAPVA KVKPSDFEKA AKRACKLNLK 400
    DAEAAYPGVQ KDNIPYICMD LVYQYTLLVD GFGVGSHQEM TLVKKVPYSN 450
    AFVEAAWPLG SAIEVAS 467
    Length:467
    Mass (Da):50,438
    Last modified:July 5, 2004 - v1
    Checksum:i22B61F6F36D43C3E
    GO

    Sequence cautioni

    The sequence AK066262 differs from that shown. Reason: Erroneous termination at position 464. Translated as Glu.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005167 Genomic DNA. Translation: BAC83798.1.
    AP008213 Genomic DNA. Translation: BAF22577.1.
    CM000144 Genomic DNA. Translation: EAZ41118.1.
    AK066262 mRNA. No translation available.
    RefSeqiNP_001060663.1. NM_001067198.1.
    UniGeneiOs.26730.

    Genome annotation databases

    GeneIDi4344315.
    KEGGiosa:4344315.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005167 Genomic DNA. Translation: BAC83798.1 .
    AP008213 Genomic DNA. Translation: BAF22577.1 .
    CM000144 Genomic DNA. Translation: EAZ41118.1 .
    AK066262 mRNA. No translation available.
    RefSeqi NP_001060663.1. NM_001067198.1.
    UniGenei Os.26730.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q6Z4P2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4344315.
    KEGGi osa:4344315.

    Organism-specific databases

    Gramenei Q6Z4P2.

    Phylogenomic databases

    eggNOGi COG5371.
    KOi K14641.
    OMAi DNIPYIC.

    Family and domain databases

    InterProi IPR000407. GDA1_CD39_NTPase.
    [Graphical view ]
    PANTHERi PTHR11782. PTHR11782. 1 hit.
    Pfami PF01150. GDA1_CD39. 1 hit.
    [Graphical view ]
    PROSITEi PS01238. GDA1_CD39_NTPASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    3. "The genomes of Oryza sativa: a history of duplications."
      Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
      , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
      PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiAPY2_ORYSJ
    AccessioniPrimary (citable) accession number: Q6Z4P2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2012
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3