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Q6Z4P2 (APY2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable apyrase 2

Short name=OsAPY2
EC=3.6.1.5
Alternative name(s):
ATP-diphosphatase
ATP-diphosphohydrolase
Adenosine diphosphatase
Short name=ADPase
Gene names
Name:APY2
Ordered Locus Names:Os07g0682800, LOC_Os07g48430
ORF Names:OsJ_25612, OSJNBa0060O17.4
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length467 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates By similarity.

Catalytic activity

A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

Cofactor

Calcium By similarity.

Subcellular location

Membrane; Single-pass type II membrane protein By similarity.

Sequence similarities

Belongs to the GDA1/CD39 NTPase family.

Sequence caution

The sequence AK066262 differs from that shown. Reason: Erroneous termination at position 464. Translated as Glu.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   LigandATP-binding
Calcium
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpollen germination

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentendosome

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

trans-Golgi network

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

guanosine-diphosphatase activity

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

inosine-diphosphatase activity

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

uridine-diphosphatase activity

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 467467Probable apyrase 2
PRO_0000419908

Regions

Topological domain1 – 2525Cytoplasmic Potential
Transmembrane26 – 4621Helical; Signal-anchor for type II membrane protein; Potential
Topological domain47 – 467421Extracellular Potential
Nucleotide binding70 – 8011ATP-binding Probable
Nucleotide binding216 – 22611ATP-binding Probable
Compositional bias348 – 3536Poly-Gly

Sites

Active site1921Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6Z4P2 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 22B61F6F36D43C3E

FASTA46750,438
        10         20         30         40         50         60 
MRRYSALPGG GARPDTLADR LHRYRGVLLV ILAPLALVSL VLLLMPRSPA SSSAAAGRRW 

        70         80         90        100        110        120 
GPLDANKYAV IFDAGSSGSR VHVFRFDANL DLLHIGDQIE LFVQKKPGLS EYANNPQEAA 

       130        140        150        160        170        180 
KSLVSLLEDA KRVVPVELRG QTPVRVGATA GLRALGAEKS EEILQAVRDL LREKSSFKTQ 

       190        200        210        220        230        240 
PDWVTVLDGP QEGAYEWVTI NYLLGKLGKT YADTVGVVDL GGGSVQMAYA IAEKDAVKAP 

       250        260        270        280        290        300 
KPSEGEDSYV KKLFLKGTTY YLYVHSYLHY GLLAARAEIL KAGNGKGYSY CTLEGHQGQY 

       310        320        330        340        350        360 
KYGNGKFEAS ASPSGASYSK CRDDVVKALK VDQACTHMKC SFGGIWNGGG GAGQKNLFVA 

       370        380        390        400        410        420 
SFFFDRAAEA GFVNPKAPVA KVKPSDFEKA AKRACKLNLK DAEAAYPGVQ KDNIPYICMD 

       430        440        450        460 
LVYQYTLLVD GFGVGSHQEM TLVKKVPYSN AFVEAAWPLG SAIEVAS 

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP005167 Genomic DNA. Translation: BAC83798.1.
AP008213 Genomic DNA. Translation: BAF22577.1.
CM000144 Genomic DNA. Translation: EAZ41118.1.
AK066262 mRNA. No translation available.
RefSeqNP_001060663.1. NM_001067198.1.
UniGeneOs.26730.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ6Z4P2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4344315.
KEGGosa:4344315.

Organism-specific databases

GrameneQ6Z4P2.

Phylogenomic databases

eggNOGCOG5371.
KOK14641.
OMADNIPYIC.

Family and domain databases

InterProIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERPTHR11782. PTHR11782. 1 hit.
PfamPF01150. GDA1_CD39. 1 hit.
[Graphical view]
PROSITEPS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAPY2_ORYSJ
AccessionPrimary (citable) accession number: Q6Z4P2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2012
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations