Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable apyrase 2

Gene

APY2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates.By similarity

Catalytic activityi

A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

Cofactori

Ca2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei192Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi70 – 80ATP-bindingCuratedAdd BLAST11
Nucleotide bindingi216 – 226ATP-bindingCuratedAdd BLAST11

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Calcium, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-8850843 Phosphate bond hydrolysis by NTPDase proteins

Names & Taxonomyi

Protein namesi
Recommended name:
Probable apyrase 2 (EC:3.6.1.5)
Short name:
OsAPY2
Alternative name(s):
ATP-diphosphatase
ATP-diphosphohydrolase
Adenosine diphosphatase
Short name:
ADPase
Gene namesi
Name:APY2
Ordered Locus Names:Os07g0682800, LOC_Os07g48430
ORF Names:OsJ_25612, OSJNBa0060O17.4
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25CytoplasmicSequence analysisAdd BLAST25
Transmembranei26 – 46Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini47 – 467ExtracellularSequence analysisAdd BLAST421

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004199081 – 467Probable apyrase 2Add BLAST467

Proteomic databases

PaxDbiQ6Z4P2

Expressioni

Gene expression databases

ExpressionAtlasiQ6Z4P2 differential
GenevisibleiQ6Z4P2 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os07g48430.1

Structurei

3D structure databases

SMRiQ6Z4P2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi348 – 353Poly-Gly6

Sequence similaritiesi

Belongs to the GDA1/CD39 NTPase family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1385 Eukaryota
COG5371 LUCA
InParanoidiQ6Z4P2
KOiK14641
OrthoDBiEOG09360CC7

Family and domain databases

InterProiView protein in InterPro
IPR000407 GDA1_CD39_NTPase
PANTHERiPTHR11782 PTHR11782, 1 hit
PfamiView protein in Pfam
PF01150 GDA1_CD39, 1 hit
PROSITEiView protein in PROSITE
PS01238 GDA1_CD39_NTPASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q6Z4P2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRYSALPGG GARPDTLADR LHRYRGVLLV ILAPLALVSL VLLLMPRSPA
60 70 80 90 100
SSSAAAGRRW GPLDANKYAV IFDAGSSGSR VHVFRFDANL DLLHIGDQIE
110 120 130 140 150
LFVQKKPGLS EYANNPQEAA KSLVSLLEDA KRVVPVELRG QTPVRVGATA
160 170 180 190 200
GLRALGAEKS EEILQAVRDL LREKSSFKTQ PDWVTVLDGP QEGAYEWVTI
210 220 230 240 250
NYLLGKLGKT YADTVGVVDL GGGSVQMAYA IAEKDAVKAP KPSEGEDSYV
260 270 280 290 300
KKLFLKGTTY YLYVHSYLHY GLLAARAEIL KAGNGKGYSY CTLEGHQGQY
310 320 330 340 350
KYGNGKFEAS ASPSGASYSK CRDDVVKALK VDQACTHMKC SFGGIWNGGG
360 370 380 390 400
GAGQKNLFVA SFFFDRAAEA GFVNPKAPVA KVKPSDFEKA AKRACKLNLK
410 420 430 440 450
DAEAAYPGVQ KDNIPYICMD LVYQYTLLVD GFGVGSHQEM TLVKKVPYSN
460
AFVEAAWPLG SAIEVAS
Length:467
Mass (Da):50,438
Last modified:July 5, 2004 - v1
Checksum:i22B61F6F36D43C3E
GO

Sequence cautioni

The sequence AK066262 differs from that shown. Reason: Erroneous termination at position 464. Translated as Glu.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005167 Genomic DNA Translation: BAC83798.1
AP008213 Genomic DNA Translation: BAF22577.1
AP014963 Genomic DNA No translation available.
CM000144 Genomic DNA Translation: EAZ41118.1
AK066262 mRNA No translation available.
RefSeqiXP_015647007.1, XM_015791521.1
UniGeneiOs.26730

Genome annotation databases

EnsemblPlantsiOs07t0682800-01; Os07t0682800-01; Os07g0682800
GeneIDi4344315
GrameneiOs07t0682800-01; Os07t0682800-01; Os07g0682800
KEGGiosa:4344315

Similar proteinsi

Entry informationi

Entry nameiAPY2_ORYSJ
AccessioniPrimary (citable) accession number: Q6Z4P2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2012
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health