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Protein

Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic

Gene

GSA

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.

Cofactori

Pathwayi

GO - Molecular functioni

  1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro
  3. transaminase activity Source: InterPro

GO - Biological processi

  1. chlorophyll biosynthetic process Source: UniProtKB-UniPathway
  2. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Chlorophyll biosynthesis, Porphyrin biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00251; UER00317.
UPA00668.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic (EC:5.4.3.8)
Short name:
GSA
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name:
GSA-AT
Gene namesi
Name:GSA
Ordered Locus Names:Os08g0532200, LOC_Os08g41990
ORF Names:P0702E04.16
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 8

Organism-specific databases

GrameneiQ6YZE2.

Subcellular locationi

Plastidchloroplast Curated

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 4040ChloroplastSequence AnalysisAdd
BLAST
Chaini41 – 478438Glutamate-1-semialdehyde 2,1-aminomutase, chloroplasticPRO_0000247473Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei318 – 3181N6-(pyridoxal phosphate)lysineBy similarity

Proteomic databases

PaxDbiQ6YZE2.
PRIDEiQ6YZE2.

Expressioni

Gene expression databases

ExpressionAtlasiQ6YZE2. baseline.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ6YZE2.
SMRiQ6YZE2. Positions 56-475.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0001.
HOGENOMiHOG000020210.
InParanoidiQ6YZE2.
KOiK01845.
OMAiCGHAHPE.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00375. HemL_aminotrans_3.
InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00713. hemL. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6YZE2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAGAAAASAA AAAVASGISA RPVAPRPSPS RARAPRSVVR AAISVEKGEK
60 70 80 90 100
AYTVEKSEEI FNAAKELMPG GVNSPVRAFK SVGGQPIVFD SVKGSRMWDV
110 120 130 140 150
DGNEYIDYVG SWGPAIIGHA DDTVNAALIE TLKKGTSFGA PCVLENVLAE
160 170 180 190 200
MVISAVPSIE MVRFVNSGTE ACMGALRLVR AFTGREKILK FEGCYHGHAD
210 220 230 240 250
SFLVKAGSGV ATLGLPDSPG VPKGATSETL TAPYNDVEAV KKLFEENKGQ
260 270 280 290 300
IAAVFLEPVV GNAGFIPPQP GFLNALRDLT KQDGALLVFD EVMTGFRLAY
310 320 330 340 350
GGAQEYFGIT PDVSTLGKII GGGLPVGAYG GRKDIMEMVA PAGPMYQAGT
360 370 380 390 400
LSGNPLAMTA GIHTLKRLME PGTYDYLDKI TGDLVRGVLD AGAKTGHEMC
410 420 430 440 450
GGHIRGMFGF FFTAGPVHNF GDAKKSDTAK FGRFYRGMLE EGVYLAPSQF
460 470
EAGFTSLAHT SQDIEKTVEA AAKVLRRI
Length:478
Mass (Da):50,238
Last modified:July 5, 2004 - v1
Checksum:i672E23E08B8A0F11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005529 Genomic DNA. Translation: BAD11647.1.
AK064826 mRNA. No translation available.
AK104694 mRNA. No translation available.
RefSeqiNP_001062337.1. NM_001068872.1.
UniGeneiOs.10144.

Genome annotation databases

EnsemblPlantsiOS08T0532200-01; OS08T0532200-01; OS08G0532200.
OS08T0532200-03; OS08T0532200-03; OS08G0532200.
GeneIDi4346136.
KEGGiosa:4346136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005529 Genomic DNA. Translation: BAD11647.1.
AK064826 mRNA. No translation available.
AK104694 mRNA. No translation available.
RefSeqiNP_001062337.1. NM_001068872.1.
UniGeneiOs.10144.

3D structure databases

ProteinModelPortaliQ6YZE2.
SMRiQ6YZE2. Positions 56-475.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ6YZE2.
PRIDEiQ6YZE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS08T0532200-01; OS08T0532200-01; OS08G0532200.
OS08T0532200-03; OS08T0532200-03; OS08G0532200.
GeneIDi4346136.
KEGGiosa:4346136.

Organism-specific databases

GrameneiQ6YZE2.

Phylogenomic databases

eggNOGiCOG0001.
HOGENOMiHOG000020210.
InParanoidiQ6YZE2.
KOiK01845.
OMAiCGHAHPE.

Enzyme and pathway databases

UniPathwayiUPA00251; UER00317.
UPA00668.

Gene expression databases

ExpressionAtlasiQ6YZE2. baseline.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00375. HemL_aminotrans_3.
InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00713. hemL. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiGSA_ORYSJ
AccessioniPrimary (citable) accession number: Q6YZE2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 5, 2004
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.