UniProtKB - Q6YZE2 (GSA_ORYSJ)
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Protein
Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic
Gene
GSA
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Catalytic activityi
(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.
Cofactori
pyridoxal 5'-phosphateBy similarity
: protoporphyrin-IX biosynthesis Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes 5-aminolevulinate from L-glutamyl-tRNA(Glu).Proteins known to be involved in the 2 steps of the subpathway in this organism are:
- Glutamyl-tRNA reductase, chloroplastic (Os10g0502400), Glutamyl-tRNA reductase (OsJ_32069)
- Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic (GSA)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-aminolevulinate from L-glutamyl-tRNA(Glu), the pathway protoporphyrin-IX biosynthesis and in Porphyrin-containing compound metabolism.
: chlorophyll biosynthesis Pathwayi
This protein is involved in the pathway chlorophyll biosynthesis, which is part of Porphyrin-containing compound metabolism.View all proteins of this organism that are known to be involved in the pathway chlorophyll biosynthesis and in Porphyrin-containing compound metabolism.
GO - Molecular functioni
- glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-EC
- pyridoxal phosphate binding Source: InterPro
- transaminase activity Source: InterPro
GO - Biological processi
- chlorophyll biosynthetic process Source: UniProtKB-UniPathway
- protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Isomerase |
Biological process | Chlorophyll biosynthesis, Porphyrin biosynthesis |
Ligand | Pyridoxal phosphate |
Enzyme and pathway databases
UniPathwayi | UPA00251; UER00317 UPA00668 |
Names & Taxonomyi
Protein namesi | Recommended name: Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic (EC:5.4.3.8)Short name: GSA Alternative name(s): Glutamate-1-semialdehyde aminotransferase Short name: GSA-AT |
Gene namesi | Name:GSA Ordered Locus Names:Os08g0532200, LOC_Os08g41990 ORF Names:OsJ_28060Imported, P0702E04.16 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 40 | ChloroplastSequence analysisAdd BLAST | 40 | |
ChainiPRO_0000247473 | 41 – 478 | Glutamate-1-semialdehyde 2,1-aminomutase, chloroplasticAdd BLAST | 438 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 318 | N6-(pyridoxal phosphate)lysineBy similarity | 1 |
Proteomic databases
PaxDbi | Q6YZE2 |
PRIDEi | Q6YZE2 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q6YZE2 baseline and differential |
Genevisiblei | Q6YZE2 OS |
Interactioni
Subunit structurei
Homodimer.By similarity
Protein-protein interaction databases
STRINGi | 39947.LOC_Os08g41990.1 |
Structurei
3D structure databases
ProteinModelPortali | Q6YZE2 |
SMRi | Q6YZE2 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | ENOG410IPFV Eukaryota COG0001 LUCA |
HOGENOMi | HOG000020210 |
InParanoidi | Q6YZE2 |
KOi | K01845 |
OMAi | WGPLIFG |
OrthoDBi | EOG093608WJ |
Family and domain databases
CDDi | cd00610 OAT_like, 1 hit |
Gene3Di | 3.40.640.101 hit 3.90.1150.102 hits |
HAMAPi | MF_00375 HemL_aminotrans_3, 1 hit |
InterProi | View protein in InterPro IPR004639 4pyrrol_synth_GluAld_NH2Trfase IPR005814 Aminotrans_3 IPR015424 PyrdxlP-dep_Trfase IPR015422 PyrdxlP-dep_Trfase_dom1 IPR015421 PyrdxlP-dep_Trfase_major |
Pfami | View protein in Pfam PF00202 Aminotran_3, 1 hit |
SUPFAMi | SSF53383 SSF53383, 1 hit |
TIGRFAMsi | TIGR00713 hemL, 1 hit |
PROSITEi | View protein in PROSITE PS00600 AA_TRANSFER_CLASS_3, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q6YZE2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGAAAASAA AAAVASGISA RPVAPRPSPS RARAPRSVVR AAISVEKGEK
60 70 80 90 100
AYTVEKSEEI FNAAKELMPG GVNSPVRAFK SVGGQPIVFD SVKGSRMWDV
110 120 130 140 150
DGNEYIDYVG SWGPAIIGHA DDTVNAALIE TLKKGTSFGA PCVLENVLAE
160 170 180 190 200
MVISAVPSIE MVRFVNSGTE ACMGALRLVR AFTGREKILK FEGCYHGHAD
210 220 230 240 250
SFLVKAGSGV ATLGLPDSPG VPKGATSETL TAPYNDVEAV KKLFEENKGQ
260 270 280 290 300
IAAVFLEPVV GNAGFIPPQP GFLNALRDLT KQDGALLVFD EVMTGFRLAY
310 320 330 340 350
GGAQEYFGIT PDVSTLGKII GGGLPVGAYG GRKDIMEMVA PAGPMYQAGT
360 370 380 390 400
LSGNPLAMTA GIHTLKRLME PGTYDYLDKI TGDLVRGVLD AGAKTGHEMC
410 420 430 440 450
GGHIRGMFGF FFTAGPVHNF GDAKKSDTAK FGRFYRGMLE EGVYLAPSQF
460 470
EAGFTSLAHT SQDIEKTVEA AAKVLRRI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP005529 Genomic DNA Translation: BAD11647.1 AP008214 Genomic DNA Translation: BAF24251.1 AP014964 Genomic DNA Translation: BAT06404.1 CM000145 Genomic DNA Translation: EAZ43454.1 AK064826 mRNA Translation: BAG89226.1 AK104694 mRNA Translation: BAG96887.1 |
RefSeqi | XP_015650872.1, XM_015795386.1 |
UniGenei | Os.10144 |
Genome annotation databases
EnsemblPlantsi | Os08t0532200-01; Os08t0532200-01; Os08g0532200 Os08t0532200-03; Os08t0532200-03; Os08g0532200 |
GeneIDi | 4346136 |
Gramenei | Os08t0532200-01; Os08t0532200-01; Os08g0532200 Os08t0532200-03; Os08t0532200-03; Os08g0532200 |
KEGGi | osa:4346136 |
Similar proteinsi
Entry informationi
Entry namei | GSA_ORYSJ | |
Accessioni | Q6YZE2Primary (citable) accession number: Q6YZE2 Secondary accession number(s): Q0J464 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 25, 2006 |
Last sequence update: | July 5, 2004 | |
Last modified: | February 28, 2018 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |