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Q6YZE2

- GSA_ORYSJ

UniProt

Q6YZE2 - GSA_ORYSJ

Protein

Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic

Gene

GSA

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.

    Cofactori

    Pyridoxal phosphate.By similarity

    Pathwayi

    GO - Molecular functioni

    1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro
    3. transaminase activity Source: InterPro

    GO - Biological processi

    1. chlorophyll biosynthetic process Source: UniProtKB-UniPathway
    2. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Chlorophyll biosynthesis, Porphyrin biosynthesis

    Keywords - Ligandi

    Pyridoxal phosphate

    Enzyme and pathway databases

    ReactomeiREACT_222250. Degradation of GABA.
    UniPathwayiUPA00251; UER00317.
    UPA00668.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic (EC:5.4.3.8)
    Short name:
    GSA
    Alternative name(s):
    Glutamate-1-semialdehyde aminotransferase
    Short name:
    GSA-AT
    Gene namesi
    Name:GSA
    Ordered Locus Names:Os08g0532200, LOC_Os08g41990
    ORF Names:P0702E04.16
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 8

    Organism-specific databases

    GrameneiQ6YZE2.

    Subcellular locationi

    Plastidchloroplast Curated

    GO - Cellular componenti

    1. apoplast Source: EnsemblPlants/Gramene
    2. chloroplast envelope Source: EnsemblPlants/Gramene
    3. chloroplast stroma Source: EnsemblPlants/Gramene

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 4040ChloroplastSequence AnalysisAdd
    BLAST
    Chaini41 – 478438Glutamate-1-semialdehyde 2,1-aminomutase, chloroplasticPRO_0000247473Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei318 – 3181N6-(pyridoxal phosphate)lysineBy similarity

    Proteomic databases

    PaxDbiQ6YZE2.
    PRIDEiQ6YZE2.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ6YZE2.
    SMRiQ6YZE2. Positions 56-475.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiCOG0001.
    HOGENOMiHOG000020210.
    KOiK01845.
    OMAiKRLMEPG.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 2 hits.
    HAMAPiMF_00375. HemL_aminotrans_3.
    InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR00713. hemL. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6YZE2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGAAAASAA AAAVASGISA RPVAPRPSPS RARAPRSVVR AAISVEKGEK    50
    AYTVEKSEEI FNAAKELMPG GVNSPVRAFK SVGGQPIVFD SVKGSRMWDV 100
    DGNEYIDYVG SWGPAIIGHA DDTVNAALIE TLKKGTSFGA PCVLENVLAE 150
    MVISAVPSIE MVRFVNSGTE ACMGALRLVR AFTGREKILK FEGCYHGHAD 200
    SFLVKAGSGV ATLGLPDSPG VPKGATSETL TAPYNDVEAV KKLFEENKGQ 250
    IAAVFLEPVV GNAGFIPPQP GFLNALRDLT KQDGALLVFD EVMTGFRLAY 300
    GGAQEYFGIT PDVSTLGKII GGGLPVGAYG GRKDIMEMVA PAGPMYQAGT 350
    LSGNPLAMTA GIHTLKRLME PGTYDYLDKI TGDLVRGVLD AGAKTGHEMC 400
    GGHIRGMFGF FFTAGPVHNF GDAKKSDTAK FGRFYRGMLE EGVYLAPSQF 450
    EAGFTSLAHT SQDIEKTVEA AAKVLRRI 478
    Length:478
    Mass (Da):50,238
    Last modified:July 5, 2004 - v1
    Checksum:i672E23E08B8A0F11
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005529 Genomic DNA. Translation: BAD11647.1.
    AK064826 mRNA. No translation available.
    AK104694 mRNA. No translation available.
    RefSeqiNP_001062337.1. NM_001068872.1.
    UniGeneiOs.10144.

    Genome annotation databases

    EnsemblPlantsiOS08T0532200-01; OS08T0532200-01; OS08G0532200.
    OS08T0532200-03; OS08T0532200-03; OS08G0532200.
    GeneIDi4346136.
    KEGGiosa:4346136.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005529 Genomic DNA. Translation: BAD11647.1 .
    AK064826 mRNA. No translation available.
    AK104694 mRNA. No translation available.
    RefSeqi NP_001062337.1. NM_001068872.1.
    UniGenei Os.10144.

    3D structure databases

    ProteinModelPortali Q6YZE2.
    SMRi Q6YZE2. Positions 56-475.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q6YZE2.
    PRIDEi Q6YZE2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS08T0532200-01 ; OS08T0532200-01 ; OS08G0532200 .
    OS08T0532200-03 ; OS08T0532200-03 ; OS08G0532200 .
    GeneIDi 4346136.
    KEGGi osa:4346136.

    Organism-specific databases

    Gramenei Q6YZE2.

    Phylogenomic databases

    eggNOGi COG0001.
    HOGENOMi HOG000020210.
    KOi K01845.
    OMAi KRLMEPG.

    Enzyme and pathway databases

    UniPathwayi UPA00251 ; UER00317 .
    UPA00668 .
    Reactomei REACT_222250. Degradation of GABA.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 2 hits.
    HAMAPi MF_00375. HemL_aminotrans_3.
    InterProi IPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR00713. hemL. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiGSA_ORYSJ
    AccessioniPrimary (citable) accession number: Q6YZE2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 25, 2006
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3