Q6YYZ2 (4CLL3_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
4-coumarate--CoA ligase-like 3
EC=6.2.1.-

Gene names

Name:	4CLL3
Ordered Locus Names:	Os08g0143300, LOC_Os08g04770
ORF Names:	P0025F03.16, P0473D02.38

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	591 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Domain	Both substrate-binding domains (SBD1 and SBD2) are involved in the substrate recognition, and are sufficient to confer the substrate specificity.
Sequence similarities	Belongs to the ATP-dependent AMP-binding enzyme family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 591	591	4-coumarate--CoA ligase-like 3		PRO_0000351629
Regions
	Nucleotide binding	228 – 236	9	ATP By similarity
	Nucleotide binding	376 – 381	6	ATP By similarity
	Region	303 – 375	73	SBD1
	Region	376 – 440	65	SBD2
Sites
	Binding site	459	1	ATP By similarity
	Binding site	474	1	ATP By similarity
	Binding site	565	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6YYZ2 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B128A79F1B0934C1	FASTA	591	62,081
	10 20 30 40 50 60 MQRDAIAAAR NAGCSSGRIS QPPPPPFYSA ATGIYSSIHP PVALPTDPSL TLVAHLFARL 70 80 90 100 110 120 PLADPGAPTL VDAATASAVS RADLRRLVAS LAAGLRRRHG VRKGSVVLLL LPNSVAFPVS 130 140 150 160 170 180 FLAVLAAGAV ATTMNPSSSP AEIAAQARAT GACLVLASRD GAARLPPLAA PVVLVPEILD 190 200 210 220 230 240 HSAAADDGDD DQRVFAAFRA MLDGGGGDGT ETAVPVVGQD DAVAILYSSG TSGRSKGVVL 250 260 270 280 290 300 THRNLIAMTE LFVRFEASQY HARGARENVY MAALPMSHVY GLSLFAVGLL SIGATVVVMR 310 320 330 340 350 360 RFDAGDAVAA IGRYKVTHMP LVPPIMAAMV RAAAAGGVPP SQVASLVQVS CGAAPITAAL 370 380 390 400 410 420 IHEFLQAFPH VDFIQGYGMT ESTAVGTRGF NTSKHKKYTS VGLLAPNMHA KIVHLESSSC 430 440 450 460 470 480 LPPGFSGELW LHGPGIMKGY LSDDDDACTR KDGWLRTGDI AYFDLDGYLY IVGRLKDTIK 490 500 510 520 530 540 YKGFQIAPGD LEEVLIHHPE ILDVAVTSAE DEEAGEIPVA FVVRRSGSNL SCKQVMEYVA 550 560 570 580 590 KQVAPYKRVR KVVFVEAIPK SPAGKVLRRL LRNSHDTAAA ATSSCSISSK L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella." de Azevedo Souza C., Barbazuk B., Ralph S.G., Bohlmann J., Hamberger B., Douglas C.J. New Phytol. 179:987-1003(2008) [PubMed: 18627494] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP005542 Genomic DNA. Translation: BAD13196.1. AP004381 Genomic DNA. Translation: BAD17022.1.
RefSeq	NP_001175376.1. NM_001188447.1.
UniGene	Os.60700.
3D structure databases
HSSP	HSSP built from PDB template 1LCI based on UniProtKB P08659.
ProteinModelPortal	Q6YYZ2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os08g04770.1; LOC_Os08g04770.1; LOC_Os08g04770.
GeneID	9269113.
KEGG	osa:9269113.
Organism-specific databases
Gramene	Q6YYZ2.
Phylogenomic databases
GeneTree	EPGT00070000028073.
OMA	EASQYEY.
Family and domain databases
InterPro	IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

4CLL3_ORYSJ

Accession

Primary (citable) accession number: Q6YYZ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 14, 2008
Last sequence update:	July 5, 2004
Last modified:	September 21, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program