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Q6YXY2

- HACL1_ORYSJ

UniProt

Q6YXY2 - HACL1_ORYSJ

Protein

Probable histone acetyltransferase HAC-like 1

Gene

Os02g0137500

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 2 (09 Jan 2007)
      Previous versions | rss
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    Functioni

    Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation By similarity.By similarity

    Catalytic activityi

    Acetyl-CoA + [histone] = CoA + acetyl-[histone].

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri651 – 73282TAZ-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri1002 – 107978PHD-typeAdd
    BLAST
    Zinc fingeri1411 – 145848ZZ-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri1553 – 163482TAZ-type 2PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. histone acetyltransferase activity Source: UniProtKB-EC
    2. transcription cofactor activity Source: InterPro
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator, Acyltransferase, Chromatin regulator, Transferase

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable histone acetyltransferase HAC-like 1 (EC:2.3.1.48)
    Gene namesi
    Ordered Locus Names:Os02g0137500, LOC_Os02g04490
    ORF Names:OSJNBa0026E05.8, OSJNBa0081C13.32
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 2

    Organism-specific databases

    GrameneiQ6YXY2.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 16681668Probable histone acetyltransferase HAC-like 1PRO_0000269745Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ6YXY2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili1342 – 136524Sequence AnalysisAdd
    BLAST
    Coiled coili1630 – 165021Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi111 – 13525Gln-richAdd
    BLAST
    Compositional biasi397 – 620224Gln-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 PHD-type zinc finger.Curated
    Contains 2 TAZ-type zinc fingers.PROSITE-ProRule annotation
    Contains 1 ZZ-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri651 – 73282TAZ-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri1002 – 107978PHD-typeAdd
    BLAST
    Zinc fingeri1411 – 145848ZZ-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri1553 – 163482TAZ-type 2PROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Coiled coil, Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG269711.
    KOiK04498.

    Family and domain databases

    Gene3Di1.20.1020.10. 2 hits.
    3.30.40.10. 1 hit.
    InterProiIPR013178. Histone_H3-K56_AcTrfase_RTT109.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR000197. Znf_TAZ.
    IPR000433. Znf_ZZ.
    [Graphical view]
    PfamiPF08214. KAT11. 1 hit.
    PF02135. zf-TAZ. 2 hits.
    [Graphical view]
    SMARTiSM00551. ZnF_TAZ. 2 hits.
    SM00291. ZnF_ZZ. 1 hit.
    [Graphical view]
    SUPFAMiSSF57903. SSF57903. 1 hit.
    SSF57933. SSF57933. 2 hits.
    PROSITEiPS01359. ZF_PHD_1. 1 hit.
    PS50134. ZF_TAZ. 2 hits.
    PS01357. ZF_ZZ_1. 1 hit.
    PS50135. ZF_ZZ_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6YXY2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNVGQAAHLS GQMSGQAPQT NQVGGSGVGG ADGLPQQMQD VVGLGGLDTQ     50
    FLLMRNTMRD RIFEYIGRKQ SSTDWRRRLP ELAKRLEEIL YRKFLNKADY 100
    LNMMRGPVEP QLQFAIKTLS AQNQQNQQNQ QMPRQMASSS GYGTMIPTPG 150
    ITQSATGNSR MPYVTDNTGL PSSGATMVPQ GANTGSMSNG YQHLTTSVPL 200
    NSTTSSIPST MGPVGIQRQV THMIPTPGFN NQQNVPVNPD FSNGAGYFNG 250
    EPTVTSQMQQ QKQFPSNQNS HQIQHIGGHS NSGMHSNMLE NSSAYGLSDG 300
    HVNGGMGVHG SNMQLTNRSA ASEAYINIST YGNSPKPVQQ QFNQHPPQRI 350
    PTPVDISGSG NFYNTGSSAL TAANNHSMGA TNLPSRSRMN SMLHTNQLNM 400
    QSIQPQPQIK TEVLDQPEKM NFQSSQLTHE QLIRQQHSMQ QHQMQPSSQF 450
    VQNQYHLNQQ QPNSQHQQSI LRSNSLKQPQ LSSSHSMQLS EQGALPHTEL 500
    ISSQATEHAD IPIYQGQYQQ RSAHDNVKGG QVFGHLSSSQ NFHSNASHDS 550
    QQLLPTNQQL DDSSNDVSYV LKGSQPEQMH QAQWRPQTME KAPVTNDSSL 600
    EKQIQADLCQ RTMSQDGAQQ PFSSDWRLPG CTVTPADPAL PKLPSGGLEQ 650
    AAGNIYYFRQ MKWLLLLFHA KSCLTPVGSC KFHRCFQVQE LVKHFENCKR 700
    KDCSYRDCRR SRMVTEHYKA CVDLQCPVCS NAKKLLQRSA ELASKQKPPE 750
    PRKIAQQNTA QRIMNGVEGD IMDIDLVSDE IFDSQPSVPK RLKMQPVSPS 800
    TAEREVSMPS NAGLILQETH SELPDQNNKV GQLKMDVKID PRPLQKPAKI 850
    GYGTDGNVPT ARHNVAPGGS NEIKTHVKQE IMPIDKETSE TAPEVKNEAN 900
    DSTDITVSKS GKPKIKGVSM TELFTPEQIQ EHINSLRLWV GQSKAKAEKN 950
    QLMGHNENEN SCQLCKVEKL TFEPPPIYCS PCGARIKRNA PYYTVGTGDT 1000
    RHFFCIPCYN ESRGDTIEVE GQNFLKARFE KKRNDEETEE WWVQCDKCEC 1050
    WQHQICALFN GRRNDGGQAE YTCPNCYVEE VKRGLRMPLP QSAVLGAKDL 1100
    PRTVLSDHIE DRLFKRLKQE RQDRAAQERK SIEEVPGAEG LVVRVVSSVD 1150
    KKLEVKPRFL EIFQEDNYPT EFPYKSKAVL LFQKIEGVEV CLFGMYVQEF 1200
    GAECSYPNQR RVYLSYLDSV KYFRPEIRTV SGEALRTFVY HEILIGYLEY 1250
    CKQRGFTSCY IWACPPLKGE DYILYCHPEI QKTPKSDKLR EWYLSMLRKA 1300
    TKEEIVVELT NLYDHFFITM GECKAKVTAS RLPYFDGDYW PGAAEDMINQ 1350
    LRQEEDDRKQ QKKGKTKKII TKRALKAAGH TDLSGNASKD AMLMHKLGET 1400
    IYPMKEDFIM VHLQYSCSHC CTLMVSGKRW VCHQCRSFYI CDKCYDAEQQ 1450
    LEDRERHPSN SRDTHTLHPV DIVGLPKDTK DRDDILESEF FDTRQAFLSL 1500
    CQGNHYQYDT LRRAKHSSMM VLYHLHNPTA PAFVTTCNVC CHDIETGQGW 1550
    RCEVCPDFDL RKMLDLLVHA STCRSGSCQY PNCRKVKGLF RHGMQCKTRA 1600
    SGGCVLCKKM WYMLQLHARA CRDSGCNVPR CRDLKEHLRR LQQQSDSRRR 1650
    AAVNEMMRQR AAEVAANE 1668
    Length:1,668
    Mass (Da):188,439
    Last modified:January 9, 2007 - v2
    Checksum:i3319FB6DD28BB3DC
    GO

    Sequence cautioni

    The sequence BAD10378.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence BAD10522.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence BAF07744.2 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005647 Genomic DNA. Translation: BAD10522.1. Sequence problems.
    AP005474 Genomic DNA. Translation: BAD10378.1. Sequence problems.
    AP008208 Genomic DNA. Translation: BAF07744.2. Sequence problems.
    RefSeqiNP_001045830.2. NM_001052365.2.
    UniGeneiOs.59276.

    Genome annotation databases

    GeneIDi4328238.
    KEGGiosa:4328238.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP005647 Genomic DNA. Translation: BAD10522.1 . Sequence problems.
    AP005474 Genomic DNA. Translation: BAD10378.1 . Sequence problems.
    AP008208 Genomic DNA. Translation: BAF07744.2 . Sequence problems.
    RefSeqi NP_001045830.2. NM_001052365.2.
    UniGenei Os.59276.

    3D structure databases

    ProteinModelPortali Q6YXY2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4328238.
    KEGGi osa:4328238.

    Organism-specific databases

    Gramenei Q6YXY2.

    Phylogenomic databases

    eggNOGi NOG269711.
    KOi K04498.

    Family and domain databases

    Gene3Di 1.20.1020.10. 2 hits.
    3.30.40.10. 1 hit.
    InterProi IPR013178. Histone_H3-K56_AcTrfase_RTT109.
    IPR019786. Zinc_finger_PHD-type_CS.
    IPR011011. Znf_FYVE_PHD.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR000197. Znf_TAZ.
    IPR000433. Znf_ZZ.
    [Graphical view ]
    Pfami PF08214. KAT11. 1 hit.
    PF02135. zf-TAZ. 2 hits.
    [Graphical view ]
    SMARTi SM00551. ZnF_TAZ. 2 hits.
    SM00291. ZnF_ZZ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57903. SSF57903. 1 hit.
    SSF57933. SSF57933. 2 hits.
    PROSITEi PS01359. ZF_PHD_1. 1 hit.
    PS50134. ZF_TAZ. 2 hits.
    PS01357. ZF_ZZ_1. 1 hit.
    PS50135. ZF_ZZ_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.

    Entry informationi

    Entry nameiHACL1_ORYSJ
    AccessioniPrimary (citable) accession number: Q6YXY2
    Secondary accession number(s): Q0E444
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 61 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3