Q6YXT7 (GUN19_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endoglucanase 19
EC=3.2.1.4

Alternative name(s):
Endo-1,4-beta glucanase 19

Gene names

Ordered Locus Names:	Os08g0114200, LOC_Os08g02220
ORF Names:	P0427G12.14

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	523 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 9 (cellulase E) family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Cell wall biogenesis/degradation Cellulose degradation Polysaccharide degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellulose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cellulase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 52	52	Potential
	Chain	53 – 523	471	Endoglucanase 19		PRO_0000249296
Sites
	Active site	442	1	By similarity
	Active site	493	1	By similarity
	Active site	502	1	By similarity
Amino acid modifications
	Glycosylation	279	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q6YXT7 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F047BC4FC913A022	FASTA	523	56,214
	10 20 30 40 50 60 MCSWSLSSHT LTSPVRQAAM EPKSSSCGGA GIRLRLLVVL HLLLLVPSSA MAFNYADALA 70 80 90 100 110 120 KSIIFFEGQR SGKLPPGNRM PWRADSGLTD GAQYNVDLVG GYYDAGDNVK FGLPMAFSTT 130 140 150 160 170 180 MLAWSVLDFG KFMGAELPNA RAAVRWGADY LLKAATATPG ALYVQVADPN QDHRCWERPE 190 200 210 220 230 240 DMDTPRSVYR VTADKPGSDV AGETAAALAA SSMVFRRADP AYSARLLHAA TQVFDFADRH 250 260 270 280 290 300 RGSYSDSLAS SVCPFYCSYS GYHDELLWGA SWLHRASRNA SFMSYVEANG MQLGAGDDDY 310 320 330 340 350 360 SFSWDDKRVG TKVLLAKGFL RNRLHGLELY KAHSDSYICS LVPGTASFQS RYTPGGLLYR 370 380 390 400 410 420 EGSSNMQYVT TATFLMLAYA KYLRSSGATA SCGDGGGGAR GEVSAAELVA VAKRQVDYIL 430 440 450 460 470 480 GKNPAGMSYM VGFGCRYPRR AHHRGASMPS VRAHPGRISC DAGFGYLHSG EPNPNVLVGA 490 500 510 520 VVGGPDSRDA FADDRGNFAQ SEPATYINAP LVGALAYFAG TTK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP005657 Genomic DNA. Translation: BAD10555.1. AP008214 Genomic DNA. Translation: BAF22762.1. AK106851 mRNA. Translation: BAG97853.1.
RefSeq	NP_001060848.1. NM_001067383.1.
UniGene	Os.54829.
3D structure databases
HSSP	HSSP built from PDB template 1TF4 based on UniProtKB P26221.
ProteinModelPortal	Q6YXT7.
ModBase	Search...
Protein family/group databases
CAZy	GH9. Glycoside Hydrolase Family 9.
Proteomic databases
PaxDb	Q6YXT7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os08g02220.1; LOC_Os08g02220.1; LOC_Os08g02220.
GeneID	4344508.
KEGG	osa:4344508.
Organism-specific databases
Gramene	Q6YXT7.
Phylogenomic databases
eggNOG	NOG05134.
HOGENOM	HOG000021033.
OMA	LPPGNRM.
ProtClustDB	CLSN2697079.
Gene expression databases
ArrayExpress	Q6YXT7.
Family and domain databases
Gene3D	1.50.10.10. 1 hit.
InterPro	IPR008928. 6-hairpin_glycosidase-like. IPR012341. 6hp_glycosidase. IPR001701. Glyco_hydro_9. IPR018221. Glyco_hydro_9_AS. [Graphical view]
Pfam	PF00759. Glyco_hydro_9. 1 hit. [Graphical view]
SUPFAM	SSF48208. Glyco_trans_6hp. 1 hit.
PROSITE	PS00592. GLYCOSYL_HYDROL_F9_1. False negative. PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GUN19_ORYSJ

Accession

Primary (citable) accession number: Q6YXT7
Secondary accession number(s): Q0J8F3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program