Reviewed, UniProtKB/Swiss-Prot Q6YW46 (EF1G2_ORYSJ)

Names and origin

Protein names

Recommended name:
    Elongation factor 1-gamma 2
      Short name=EF-1-gamma 2
Alternative name(s):
    eEF-1B gamma 2

Gene names

Ordered Locus Names:	Os02g0220500, LOC_Os02g12800
ORF Names:	B1131G07.11

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components By similarity.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Coding sequence diversity	Alternative splicing
Molecular function	Elongation factor
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: InterPro
Cellular component	eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q6YW46-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q6YW46-2)

The sequence of this isoform differs from the canonical sequence as follows:
     237-240: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 418	418	Elongation factor 1-gamma 2		PRO_0000228123
Regions
	Domain	1 – 82	82	GST N-terminal
	Domain	87 – 215	129	GST C-terminal
	Domain	258 – 418	161	EF-1-gamma C-terminal
Natural variations
	Alternative sequence	237 – 240	4	Missing in isoform 2.		VSP_017654

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 21, 2006. Version 2. Checksum: 73C7123AB0605E56	FASTA	418	47,356
	10 20 30 40 50 60 MALVLHAGSG NKNAFKALIA AEYSGVKVEL VKNFQMGVSN KTPEFLKMNP IGKIPVLETP 70 80 90 100 110 120 DGPVFESNAI ARYVTRSKAD NPLYGSSLIE YAHIEQWNDF SATEVDANIG KWLYPRLGIA 130 140 150 160 170 180 PYVAVSEEAA IAALKRSLGA LNTHLASNTY LVGHSVTLAD IVMTCNLYMG FARIMTKSFT 190 200 210 220 230 240 SEFPHVERYF WTMVNQPNFK KVLGDVKQAE SVPPVQKKAP PPKEQKPKEA KKEAPKEAPK 250 260 270 280 290 300 PKAVEKPEEE EEAPKPKPKN PLDLLPPSKM ILDEWKRLYS NTKTNFREVA IKGFWDMYDP 310 320 330 340 350 360 EGYSLWFCDY KYNDENTVSF VTMNKVGGFL QRMDLCRKYA FGKMLVIGSE PPFKVKGLWL 370 380 390 400 410 FRGPEIPKFV MDEVYDMELY EWTKVDISDE AQKERVSAMI EDLEPFEGES LLDAKCFK
	Isoform 2. Checksum: 276119311BE75736	FASTA	414	46,930
	10 20 30 40 50 60 MALVLHAGSG NKNAFKALIA AEYSGVKVEL VKNFQMGVSN KTPEFLKMNP IGKIPVLETP 70 80 90 100 110 120 DGPVFESNAI ARYVTRSKAD NPLYGSSLIE YAHIEQWNDF SATEVDANIG KWLYPRLGIA 130 140 150 160 170 180 PYVAVSEEAA IAALKRSLGA LNTHLASNTY LVGHSVTLAD IVMTCNLYMG FARIMTKSFT 190 200 210 220 230 240 SEFPHVERYF WTMVNQPNFK KVLGDVKQAE SVPPVQKKAP PPKEQKPKEA KKEAPKPKAV 250 260 270 280 290 300 EKPEEEEEAP KPKPKNPLDL LPPSKMILDE WKRLYSNTKT NFREVAIKGF WDMYDPEGYS 310 320 330 340 350 360 LWFCDYKYND ENTVSFVTMN KVGGFLQRMD LCRKYAFGKM LVIGSEPPFK VKGLWLFRGP 370 380 390 400 410 EIPKFVMDEV YDMELYEWTK VDISDEAQKE RVSAMIEDLE PFEGESLLDA KCFK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Oryza sativa nipponbare chromosome 2 genomic DNA sequence." The international rice genome sequencing project (IRGSP) consortium Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Strain: cv. Nipponbare.
[3]	"A network of rice genes associated with stress response and seed development." Cooper B., Clarke J.D., Budworth P., Kreps J., Hutchison D., Park S., Guimil S., Dunn M., Luginbuehl P., Ellero C., Goff S.A., Glazebrook J. Proc. Natl. Acad. Sci. U.S.A. 100:4945-4950(2003) [PubMed: 12684538] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 10-418 (ISOFORM 1). Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP005797 Genomic DNA. Translation: BAD17614.1. AK103901 mRNA. No translation available. AY224455 mRNA. Translation: AAO72574.1.
UniGene	Os.4765
3D structure databases
HSSP	HSSP built from PDB template 1PBU based on UniProtKB P26641.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6YW46. 3 interactions.
Organism-specific databases
Gramene	Q6YW46.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012335. Thioredoxin_fold. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
ProDom	PD006217. EF1_G. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G2_ORYSJ

Accession

Primary (citable) accession number: Q6YW46
Secondary accession number(s): Q84PA8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 21, 2006
Last sequence update:	March 21, 2006
Last modified:	June 16, 2009
This is version 29 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)