Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Onion yellows phytoplasma (strain OY-M)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi498MagnesiumUniRule annotation1
Metal bindingi504MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, RNA-binding, Transferase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciOYEL262768:G1G26-308-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:PAM_251
OrganismiOnion yellows phytoplasma (strain OY-M)
Taxonomic identifieri262768 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeCandidatus PhytoplasmaCandidatus Phytoplasma asteris
Proteomesi
  • UP000002523 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003297451 – 715Polyribonucleotide nucleotidyltransferaseAdd BLAST715

Interactioni

Protein-protein interaction databases

STRINGi262768.PAM_251

Structurei

3D structure databases

ProteinModelPortaliQ6YQX2
SMRiQ6YQX2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini565 – 625KHUniRule annotationAdd BLAST61
Domaini635 – 706S1 motifUniRule annotationAdd BLAST72

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QUF Bacteria
COG1185 LUCA
HOGENOMiHOG000218326
KOiK00962
OMAiRYMHNYN
OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50084 KH_TYPE_1, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Q6YQX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKVFETTN LKDSFQVEIG TYARNVDASI LVRYQDTVVL TTTVFSRKPN
60 70 80 90 100
NLDFLPLTVI YQEKLYAAGK IPGSFLRREG RSNDHEILTS RLIDRSLRPL
110 120 130 140 150
FPDYFQQEVQ VINTVLSLDP DFKSELASML GSSLSLLISE IPFFEAISGV
160 170 180 190 200
YVGKINDKFI INPTLQQLAN STLHLMVAGT KHNVTMIEAH ANEVSEQDFL
210 220 230 240 250
EAINFAHQYI KKLCLFQENI KQQFAPAKIT NTLHQTEQTQ QQAFFAKHQS
260 270 280 290 300
QVKQAILSCN SKNDLQQLKE QILDQAKQTP FFKTIDTATV FDYEAHKKHL
310 320 330 340 350
QTTETLFQKL SKQETRSLIL QEKIRPDKRG LEEIRTLESQ IDLLPRAHGS
360 370 380 390 400
ALFTRGQTQS LAAVTLGCLS ESKIIDGLSD EQNKRFMLHY NFPPFSVGAV
410 420 430 440 450
GRYTAPSRRE IGHGTLAEKA ISQVLPEEKD FPYTIRVVSE ILESNGSSSQ
460 470 480 490 500
ATVCASSLAL MASGVPLKKA VAGMSVGLVF DQATNKYVIL SDIQGLEDHV
510 520 530 540 550
GDMDLKIAGT NKGITALQMD LKIQGIHFKI LQEAFLQAKK GRLHILEHMS
560 570 580 590 600
QTISQPRLEV SKYAPKVCMM QIKPEKIRDI IGSGGKIINQ IIESHDGVKI
610 620 630 640 650
DIEQDGRVFV MHSNLETVKK TVAFIESLIQ EIQIGTCYQA SILRFLSDKQ
660 670 680 690 700
GKMIGAVAQV CPGIEGLIHV NQKKFQKITD VLKIGETVSV KCTKINDRGR
710
IDFLLLPKNT QEKNS
Length:715
Mass (Da):80,121
Last modified:July 5, 2004 - v1
Checksum:iF77537184C982E9B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006628 Genomic DNA Translation: BAD04336.1
RefSeqiWP_011160625.1, NC_005303.2

Genome annotation databases

EnsemblBacteriaiBAD04336; BAD04336; PAM_251
KEGGipoy:PAM_251

Similar proteinsi

Entry informationi

Entry nameiPNP_ONYPE
AccessioniPrimary (citable) accession number: Q6YQX2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health