Q6YNI5 (NTD_LACFE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nucleoside deoxyribosyltransferase
Short name=N-deoxyribosyltransferase
EC=2.4.2.6

Gene names

Name:

ntd

Organism

Lactobacillus fermentum

Taxonomic identifier

1613 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the cleavage of the glycosidic bond of 2'-deoxyribonucleosides and the transfer of the deoxyribosyl moiety to an acceptor purine or pyrimidine base By similarity.
Catalytic activity	2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.
Pathway	Nucleotide metabolism; nucleotide salvage pathway.
Sequence similarities	Belongs to the nucleoside deoxyribosyltransferase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Transferase
Gene Ontology (GO)
Biological_process	deoxyribonucleoside monophosphate catabolic process Inferred from electronic annotation. Source: InterPro nucleotide salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	deoxyribonucleoside 5'-monophosphate N-glycosidase activity Inferred from electronic annotation. Source: InterPro nucleoside deoxyribosyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 168	168	Nucleoside deoxyribosyltransferase		PRO_0000220065
Sites
	Active site	103	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6YNI5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 362162F43586C317	FASTA	168	18,896
	10 20 30 40 50 60 MKNTDPVANT KIYLATSFFN EEQRARIPQA LAQLEANPTV GVVHQPFDFQ YKDARVDSDP 70 80 90 100 110 120 AGVFGSLEWQ IATYNNDLNA VGTSDVCVAL YDMDQIDEGI CMEIGMFVAL HKPIVLLPFT 130 140 150 160 KKDKSAYEAN LMLARGVTTW LEPNDFSPLK DFNFNHPMAQ PFPPFKVF

References

[1]	"Characteriztion of the Lactobacillus fermentum N-deoxyribosyltransferase." Kaminski P.A. Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 14931 / DSM 20052 / JCM 1173 / NBRC 15885 / NCIMB 11840 / VTT E-93489.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY064168 Genomic DNA. Translation: AAL73115.1.
3D structure databases
ProteinModelPortal	Q6YNI5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00312.
Family and domain databases
Gene3D	3.40.50.1810. 1 hit.
InterPro	IPR007710. Nucleoside_deoxyribTrfase. [Graphical view]
Pfam	PF05014. Nuc_deoxyrib_tr. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NTD_LACFE

Accession

Primary (citable) accession number: Q6YNI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2004
Last sequence update:	July 5, 2004
Last modified:	May 29, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program