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Protein

Cytochrome c oxidase subunit 6B2

Gene

Cox6b2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. This protein may be one of the heme-binding subunits of the oxidase (By similarity).By similarity

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 6B2
Alternative name(s):
Cytochrome c oxidase subunit VIb isoform 2
Short name:
COX VIb-2
Cytochrome c oxidase subunit VIb, testis-specific isoform
Gene namesi
Name:Cox6b2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1591896. Cox6b2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8888Cytochrome c oxidase subunit 6B2PRO_0000194923Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi32 ↔ 67By similarity
Disulfide bondi42 ↔ 56By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ6YFQ1.
PRIDEiQ6YFQ1.

Expressioni

Tissue specificityi

Testis specific.1 Publication

Gene expression databases

BgeeiENSRNOG00000038616.
GenevisibleiQ6YFQ1. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000035591.

Structurei

3D structure databases

ProteinModelPortaliQ6YFQ1.
SMRiQ6YFQ1. Positions 14-88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3057. Eukaryota.
ENOG41121WM. LUCA.
GeneTreeiENSGT00390000001191.
HOGENOMiHOG000165128.
HOVERGENiHBG051090.
InParanoidiQ6YFQ1.
KOiK02267.
OMAiISWVQRW.
OrthoDBiEOG091G0UIB.
PhylomeDBiQ6YFQ1.
TreeFamiTF105065.

Family and domain databases

Gene3Di1.10.10.140. 1 hit.
InterProiIPR003213. Cyt_c_oxidase_su6B.
[Graphical view]
PfamiPF02297. COX6B. 1 hit.
[Graphical view]
PIRSFiPIRSF000278. Cyt_c_oxidase_6B. 1 hit.
SUPFAMiSSF47694. SSF47694. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6YFQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGVQAQMPA PGQWTTPPFD PRFPNQNQTR NCYQNFLDYH RCVKTMDRRG
60 70 80
KNTQACDYYF RVFHSLCPVS WVQRWNEQIK QGTFPGKI
Length:88
Mass (Da):10,472
Last modified:July 5, 2004 - v1
Checksum:iE20F30D1486EA1B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY152399 mRNA. Translation: AAN46752.1.
RefSeqiNP_001034174.1. NM_001039085.1.
UniGeneiRn.97699.

Genome annotation databases

EnsembliENSRNOT00000033197; ENSRNOP00000035591; ENSRNOG00000038616.
GeneIDi654441.
KEGGirno:654441.
UCSCiRGD:1591896. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY152399 mRNA. Translation: AAN46752.1.
RefSeqiNP_001034174.1. NM_001039085.1.
UniGeneiRn.97699.

3D structure databases

ProteinModelPortaliQ6YFQ1.
SMRiQ6YFQ1. Positions 14-88.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000035591.

Proteomic databases

PaxDbiQ6YFQ1.
PRIDEiQ6YFQ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000033197; ENSRNOP00000035591; ENSRNOG00000038616.
GeneIDi654441.
KEGGirno:654441.
UCSCiRGD:1591896. rat.

Organism-specific databases

CTDi125965.
RGDi1591896. Cox6b2.

Phylogenomic databases

eggNOGiKOG3057. Eukaryota.
ENOG41121WM. LUCA.
GeneTreeiENSGT00390000001191.
HOGENOMiHOG000165128.
HOVERGENiHBG051090.
InParanoidiQ6YFQ1.
KOiK02267.
OMAiISWVQRW.
OrthoDBiEOG091G0UIB.
PhylomeDBiQ6YFQ1.
TreeFamiTF105065.

Miscellaneous databases

PROiQ6YFQ1.

Gene expression databases

BgeeiENSRNOG00000038616.
GenevisibleiQ6YFQ1. RN.

Family and domain databases

Gene3Di1.10.10.140. 1 hit.
InterProiIPR003213. Cyt_c_oxidase_su6B.
[Graphical view]
PfamiPF02297. COX6B. 1 hit.
[Graphical view]
PIRSFiPIRSF000278. Cyt_c_oxidase_6B. 1 hit.
SUPFAMiSSF47694. SSF47694. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCX6B2_RAT
AccessioniPrimary (citable) accession number: Q6YFQ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.