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Protein

Cytochrome c oxidase subunit 6B2

Gene

Cox6b2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. This protein may be one of the heme-binding subunits of the oxidase (By similarity).By similarity

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 6B2
Alternative name(s):
Cytochrome c oxidase subunit VIb isoform 2
Short name:
COX VIb-2
Cytochrome c oxidase subunit VIb, testis-specific isoform
Gene namesi
Name:Cox6b2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1591896. Cox6b2.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001949231 – 88Cytochrome c oxidase subunit 6B2Add BLAST88

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi32 ↔ 67PROSITE-ProRule annotation
Disulfide bondi42 ↔ 56PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ6YFQ1.
PRIDEiQ6YFQ1.

Expressioni

Tissue specificityi

Testis specific.1 Publication

Gene expression databases

BgeeiENSRNOG00000038616.
GenevisibleiQ6YFQ1. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000035591.

Structurei

3D structure databases

ProteinModelPortaliQ6YFQ1.
SMRiQ6YFQ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 75CHCHPROSITE-ProRule annotationAdd BLAST47

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi32 – 42Cx9C motifPROSITE-ProRule annotationAdd BLAST11
Motifi56 – 67Cx10C motifPROSITE-ProRule annotationAdd BLAST12

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3057. Eukaryota.
ENOG41121WM. LUCA.
GeneTreeiENSGT00390000001191.
HOGENOMiHOG000165128.
HOVERGENiHBG051090.
InParanoidiQ6YFQ1.
KOiK02267.
OMAiISWVQRW.
OrthoDBiEOG091G0UIB.
PhylomeDBiQ6YFQ1.
TreeFamiTF105065.

Family and domain databases

CDDicd00926. Cyt_c_Oxidase_VIb. 1 hit.
InterProiView protein in InterPro
IPR003213. Cyt_c_oxidase_su6B.
PANTHERiPTHR11387. PTHR11387. 1 hit.
PfamiView protein in Pfam
PF02297. COX6B. 1 hit.
PIRSFiPIRSF000278. Cyt_c_oxidase_6B. 1 hit.
SUPFAMiSSF47694. SSF47694. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6YFQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGVQAQMPA PGQWTTPPFD PRFPNQNQTR NCYQNFLDYH RCVKTMDRRG
60 70 80
KNTQACDYYF RVFHSLCPVS WVQRWNEQIK QGTFPGKI
Length:88
Mass (Da):10,472
Last modified:July 5, 2004 - v1
Checksum:iE20F30D1486EA1B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY152399 mRNA. Translation: AAN46752.1.
RefSeqiNP_001034174.1. NM_001039085.1.
UniGeneiRn.97699.

Genome annotation databases

EnsembliENSRNOT00000033197; ENSRNOP00000035591; ENSRNOG00000038616.
GeneIDi654441.
KEGGirno:654441.
UCSCiRGD:1591896. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY152399 mRNA. Translation: AAN46752.1.
RefSeqiNP_001034174.1. NM_001039085.1.
UniGeneiRn.97699.

3D structure databases

ProteinModelPortaliQ6YFQ1.
SMRiQ6YFQ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000035591.

Proteomic databases

PaxDbiQ6YFQ1.
PRIDEiQ6YFQ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000033197; ENSRNOP00000035591; ENSRNOG00000038616.
GeneIDi654441.
KEGGirno:654441.
UCSCiRGD:1591896. rat.

Organism-specific databases

CTDi125965.
RGDi1591896. Cox6b2.

Phylogenomic databases

eggNOGiKOG3057. Eukaryota.
ENOG41121WM. LUCA.
GeneTreeiENSGT00390000001191.
HOGENOMiHOG000165128.
HOVERGENiHBG051090.
InParanoidiQ6YFQ1.
KOiK02267.
OMAiISWVQRW.
OrthoDBiEOG091G0UIB.
PhylomeDBiQ6YFQ1.
TreeFamiTF105065.

Miscellaneous databases

PROiPR:Q6YFQ1.

Gene expression databases

BgeeiENSRNOG00000038616.
GenevisibleiQ6YFQ1. RN.

Family and domain databases

CDDicd00926. Cyt_c_Oxidase_VIb. 1 hit.
InterProiView protein in InterPro
IPR003213. Cyt_c_oxidase_su6B.
PANTHERiPTHR11387. PTHR11387. 1 hit.
PfamiView protein in Pfam
PF02297. COX6B. 1 hit.
PIRSFiPIRSF000278. Cyt_c_oxidase_6B. 1 hit.
SUPFAMiSSF47694. SSF47694. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCX6B2_RAT
AccessioniPrimary (citable) accession number: Q6YFQ1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: July 5, 2004
Last modified: April 12, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.