Q6YFJ8 (Q6YFJ8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Paired box transcription factor EMBL AAN77899.1

Gene names

Name:

PAX2 EMBL AAN77899.1

Organism

Homo sapiens (Human) EMBL AAN77899.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	308 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU000491.
Sequence similarities	Contains 1 paired domain. RuleBase RU000491 SAAS SAAS001523

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU000491 SAAS SAAS001523
Cellular component	Nucleus RuleBase RU000491 SAAS SAAS001523
Domain	Paired box RuleBase RU000491 SAAS SAAS001523
Ligand	DNA-binding RuleBase RU000491 SAAS SAAS001523
Molecular function	Developmental protein RuleBase RU000491 SAAS SAAS001523
Gene Ontology (GO)
Biological_process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	308	1	EMBL AAN77899.1

Sequences

	Sequence		Length	Mass (Da)
	Q6YFJ8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C08BE9F0A4049A83	FASTA	308	32,788
	10 20 30 40 50 60 MAGPCCVWGV VFFSCLSPAG HGGVNQLGGV FVNGRPLPDV VRQRIVELAH QGVRPCDISR 70 80 90 100 110 120 QLRVSHGCVS KILGRYYETG SIKPGVIGGS KPKVATPKVV DKIAEYKRQN PTMFAWEIRD 130 140 150 160 170 180 RLLAEGICDN DTVPSVSSIN RIIRTKVQQP FHPTPDGAGT GVTAPGHTIV PSTASPPVSS 190 200 210 220 230 240 ASNDPVGSYS INGILGIPRS NDVSEGSVPN GDSQSGVDSL RKHLRADTFT QQQLEALDRV 250 260 270 280 290 300 FERPSYPDVF QASEHIKSEQ GNEYSLPALT PGLDEVKSSL SASTNPELGS NVSGTQTYPV VTGRDMAS

References

[1]	"Accumulation and developmental regulation of exon 1- and intron 1-containing PAX2 transcripts in fetal kidney and Wilms tumor." Zhou C., Bockett N., Eccles M.R. Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Kidney EMBL AAN77899.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY153483 mRNA. Translation: AAN77899.1.
IPI	IPI01026454.
UniGene	Hs.155644.
3D structure databases
ProteinModelPortal	Q6YFJ8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc001krp.1. human.
Phylogenomic databases
HOGENOM	HOG000230938.
HOVERGEN	HBG009115.
OrthoDB	EOG49S66H.
Gene expression databases
ArrayExpress	Q6YFJ8.
Bgee	Q6YFJ8.
Family and domain databases
Gene3D	1.10.10.10. 2 hits.
InterPro	IPR009057. Homeodomain-like. IPR001523. Paired_dom. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00292. PAX. 1 hit. [Graphical view]
PRINTS	PR00027. PAIREDBOX.
SMART	SM00351. PAX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00034. PAIRED_1. 1 hit. PS51057. PAIRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6YFJ8_HUMAN

Accession

Primary (citable) accession number: Q6YFJ8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 29, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.