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Q6XVF4

- Q6XVF4_MOUSE

UniProt

Q6XVF4 - Q6XVF4_MOUSE

Protein
Submitted name:

PSD-95 alpha

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering Source: Ensembl
    2. dendritic spine morphogenesis Source: Ensembl
    3. establishment of protein localization Source: Ensembl
    4. negative regulation of receptor internalization Source: Ensembl
    5. positive regulation of cytosolic calcium ion concentration Source: Ensembl
    6. positive regulation of excitatory postsynaptic membrane potential Source: Ensembl
    7. positive regulation of synaptic transmission Source: Ensembl
    8. protein complex assembly Source: Ensembl
    9. receptor localization to synapse Source: Ensembl
    10. regulation of N-methyl-D-aspartate selective glutamate receptor activity Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PSD-95 alphaImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Subcellular locationi

    GO - Cellular componenti

    1. cortical cytoskeleton Source: Ensembl
    2. dendrite cytoplasm Source: Ensembl
    3. excitatory synapse Source: Ensembl
    4. juxtaparanode region of axon Source: Ensembl
    5. neuronal postsynaptic density Source: Ensembl
    6. postsynaptic membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ6XVF4.
    BgeeiQ6XVF4.
    GenevestigatoriQ6XVF4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6XVF4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 2 PDZ (DHR) domains.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG104157.

    Family and domain databases

    Gene3Di2.30.42.10. 2 hits.
    InterProiIPR016313. DLG1.
    IPR019590. MAGUK_PEST_N.
    IPR001478. PDZ.
    [Graphical view]
    PANTHERiPTHR23119. PTHR23119. 1 hit.
    PfamiPF10608. MAGUK_N_PEST. 2 hits.
    PF00595. PDZ. 2 hits.
    [Graphical view]
    SMARTiSM00228. PDZ. 2 hits.
    [Graphical view]
    SUPFAMiSSF50156. SSF50156. 2 hits.
    PROSITEiPS50106. PDZ. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6XVF4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDCLCIVTTK KYRYQDEDTP PLEHSPAHLP NQANSPPVIV NTDTLEAPGY    50
    ELQVNGTEGE MEYEEITLER GNSGLGFSIA GGTDNPHIGD DPSIFITKII 100
    PGGAAAQDGR LRVNDSILFV NEVDVREVTH SAAVEALKEA GSIVRLYVMR 150
    RKPPAEKIIE IKLIKGPKGL GFSIAGGVGN QHIPGDNSIY VTKIIEGGAA 200
    HKDGRLQIGD KILAVNSVGL EDVMHEDAVA ALKNTYDVVY LKVAKPSNAY 250
    LSDSYAPPDI TT 262
    Length:262
    Mass (Da):28,145
    Last modified:July 5, 2004 - v1
    Checksum:i26EDFD568053A0ED
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei262 – 2621Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY207049, AY207048 Genomic DNA. Translation: AAQ56705.1.
    UniGeneiMm.27256.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY207049 , AY207048 Genomic DNA. Translation: AAQ56705.1 .
    UniGenei Mm.27256.

    3D structure databases

    ProteinModelPortali Q6XVF4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG104157.

    Miscellaneous databases

    ChiTaRSi DLG4. mouse.

    Gene expression databases

    ArrayExpressi Q6XVF4.
    Bgeei Q6XVF4.
    Genevestigatori Q6XVF4.

    Family and domain databases

    Gene3Di 2.30.42.10. 2 hits.
    InterProi IPR016313. DLG1.
    IPR019590. MAGUK_PEST_N.
    IPR001478. PDZ.
    [Graphical view ]
    PANTHERi PTHR23119. PTHR23119. 1 hit.
    Pfami PF10608. MAGUK_N_PEST. 2 hits.
    PF00595. PDZ. 2 hits.
    [Graphical view ]
    SMARTi SM00228. PDZ. 2 hits.
    [Graphical view ]
    SUPFAMi SSF50156. SSF50156. 2 hits.
    PROSITEi PS50106. PDZ. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analyses of murine postsynaptic density-95 identify novel isoforms and potential translational control elements."
      Bence M., Arbuckle M.I., Dickson K.S., Grant S.G.
      Brain Res. Mol. Brain Res. 133:143-152(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 129/SvEvTacfBrImported.

    Entry informationi

    Entry nameiQ6XVF4_MOUSE
    AccessioniPrimary (citable) accession number: Q6XVF4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)